Experimental and computational studies reveal an alternative supramolecular structure for fmoc-dipeptide self-assembly.

abstract：:Antibacterial nanodevices could bring coatings of plastic materials and wound dressings a big step forward if the release of the antibacterial agents could be triggered by the presence of the bacteria themselves. Here, we show that novel hyaluronic acid (HA)-based nanocapsules containing the antimicrobial agent polyhe...

journal_title：Biomacromolecules

authors： Baier G,Cavallaro A,Vasilev K,Mailänder V,Musyanovych A,Landfester K

更新日期：2013-04-08 00:00:00

abstract：:A novel pH-sensitive amphiphilic copolymer brush poly(methyl methacrylate-co-methacrylic acid)-b-poly(poly(ethylene glycol) methyl ether monomethacrylate) [P(MMA-co-MAA)-b-PPEGMA] was defined and synthesized by atom transfer radical polymerization (ATRP) technique. The molecular structures and characteristics of this ...

journal_title：Biomacromolecules

authors： Yang YQ,Zheng LS,Guo XD,Qian Y,Zhang LJ

更新日期：2011-01-10 00:00:00

abstract：:A novel family of amphiphilic temperature- and pH-sensitive poly(organophosphazenes) with varying ratios of ethylene oxide, alkyl chains and free acid units was synthesized by living cationic polymerization. Depending on their composition, these poly(organophosphazenes) exhibited lower critical solution temperatures r...

journal_title：Biomacromolecules

authors： Couffin-Hoarau AC,Leroux JC

更新日期：2004-11-01 00:00:00

abstract：:The effect of increasing water composition on the rheological and microstructural behavior of a ternary cellulose acetate (CA)/N,N-dimethylacetamide (DMA)/water system is examined. Addition of water to the CA/DMA system results in enhanced steady shear viscosity and dynamic viscoelastic properties and ultimately to ph...

journal_title：Biomacromolecules

authors： Appaw C,Gilbert RD,Khan SA,Kadla JF

更新日期：2007-05-01 00:00:00

abstract：:Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis of forisome structure and assembly, we used confocal laser scanning mi...

journal_title：Biomacromolecules

authors： Groscurth S,Müller B,Schwan S,Menzel M,Diekstall F,Senft M,Kendall A,Kommor BA,Neumann U,Kalischuk M,Kawchuk LM,Krzyzanek V,Heilmann A,Stubbs G,Twyman RM,Prüfer D,Noll GA

更新日期：2012-10-08 00:00:00

abstract：:Neutral cellulose nanocrystals dispersed in water were shown in a previous work to stabilize oil/water interfaces and produce Pickering emulsions with outstanding stability, whereas sulfated nanocrystals obtained from cotton did not show interfacial properties. To develop a better understanding of the stabilization me...

journal_title：Biomacromolecules

authors： Kalashnikova I,Bizot H,Cathala B,Capron I

更新日期：2012-01-09 00:00:00

abstract：:Polycations often suffer from the irreconcilable inconsistency between transfection efficiency and toxicity. Polymers with high molecular weight (MW) and cationic charge feature potent gene delivery capabilities, while in the meantime suffer from strong chemotoxicity, restricted intracellular DNA release, and low stab...

journal_title：Biomacromolecules

authors： He H,Bai Y,Wang J,Deng Q,Zhu L,Meng F,Zhong Z,Yin L

更新日期：2015-04-13 00:00:00

abstract：:Selectively spooling single plasmid DNA (pDNA), as a giant polyelectrolyte, into a nanosized toroidal structure or folding it into a rod-like structure has been accomplished by polyion complexation with block catiomers to form polymeric micelles in varying NaCl concentrations. The interactive potency between the pDNA ...

journal_title：Biomacromolecules

authors： Li Y,Osada K,Chen Q,Tockary TA,Dirisala A,Takeda KM,Uchida S,Nagata K,Itaka K,Kataoka K

更新日期：2015-09-14 00:00:00

abstract：:Images of high methoxyl orange pectin deposited from solution and high methoxyl sugar acid gels (HMSAG) were obtained by atomic force microscopy (AFM) in the tapping mode. For the first time, images of pectin deposited from water revealed that the transition from pectin networks to individual molecules or aggregates t...

journal_title：Biomacromolecules

authors： Fishman ML,Cooke PH,Chau HK,Coffin DR,Hotchkiss AT Jr

更新日期：2007-02-01 00:00:00

abstract：:In this work, biodegradable branched polycationic polymers were synthesized by Michael addition polymerization from different amine monomers and the triacrylate monomer trimethylolpropane triacrylate. The polymers varied in the number of amines that dissociate in different pH ranges, which are considered to be benefic...

journal_title：Biomacromolecules

authors： Chew SA,Hacker MC,Saraf A,Raphael RM,Kasper FK,Mikos AG

更新日期：2010-03-08 00:00:00

abstract：:We investigated the rheological properties and the penetration of differently sized carboxylated nanoparticles in pig pulmonary mucus, on different distance and time scales. Nanoparticles were either mechanically mixed into the mucus samples or deposited as an aerosol, the latter resembling a more physiologically rele...

journal_title：Biomacromolecules

authors： Murgia X,Pawelzyk P,Schaefer UF,Wagner C,Willenbacher N,Lehr CM

更新日期：2016-04-11 00:00:00

abstract：:Heparin, a sulfated polysaccharide derived from animal sources, is the most commonly used parenteral anticoagulant drug, but it suffers from significant safety and supply issues. Herein, we describe the preparation of heparin mimetic homo- and copolymers via the reversible addition-fragmentation chain transfer (RAFT) ...

journal_title：Biomacromolecules

authors： Nahain AA,Ignjatovic V,Monagle P,Tsanaktsidis J,Vamvounis G,Ferro V

更新日期：2020-02-10 00:00:00

abstract：:Inulin, the polydisperse reserve polysaccharide from chicory, has been modified by carbamoylation in organic solvents. The reaction of inulin with a range of alkyl isocyanates resulted, after crystalization, in a variety of carbamoylated inulins from which the interfacial properties were determined. The medium and lon...

journal_title：Biomacromolecules

authors： Stevens CV,Meriggi A,Peristeropoulou M,Christov PP,Booten K,Levecke B,Vandamme A,Pittevils N,Tadros TF

更新日期：2001-01-01 00:00:00

abstract：:Native hemicellulose lacks many of the properties that make fossil fuel-based polymers excellent for use in today's industrial products and processes. The mechanical and thermal properties of the hemicellulose can, however, be modified, and its processability increased. We functionalized galactoglucomannan to lower it...

journal_title：Biomacromolecules

authors： Härdelin L,Bernin D,Börjesson M,Ström A,Larsson A

更新日期：2020-05-11 00:00:00

abstract：:Exendin-4 (EX4), a glucagon-like peptide-1 receptor (GLP-1R) agonist that regulates blood glucose levels, has been used in the management of type-2 diabetes mellitus. EX4 can be PEGylated to improve its antidiabetic effects by enhancing its stability and extending the circulation half-life. Here, to determine whether ...

journal_title：Biomacromolecules

authors： Lee W,Park EJ,Kwak S,Lee KC,Na DH,Bae JS

更新日期：2016-03-14 00:00:00

abstract：:Specific folate receptors are abundantly overexpressed in chronically activated macrophages and in most cancer cells. Directed folate receptor targeting using liposomes is usually achieved using folate linked to a phospholipid or cholesterol anchor. This link is formed using a large spacer like polyethylene glycol. He...

journal_title：Biomacromolecules

authors： Nogueira E,Mangialavori IC,Loureiro A,Azoia NG,Sárria MP,Nogueira P,Freitas J,Härmark J,Shimanovich U,Rollett A,Lacroix G,Bernardes GJ,Guebitz G,Hebert H,Moreira A,Carmo AM,Rossi JP,Gomes AC,Preto A,Cavaco-Paulo A

更新日期：2015-09-14 00:00:00

abstract：:Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium erraticum endodextranase and the Aspergillus niger α-glucosidase was used to hydrolyze W. confusa dextran to glucose and a set...

journal_title：Biomacromolecules

authors： Maina NH,Virkki L,Pynnönen H,Maaheimo H,Tenkanen M

更新日期：2011-02-14 00:00:00

abstract：:Poly(dimethyl siloxane) (PDMS) is extensively used for biomedical applications due to its low cost, ease of fabrication, high durability and flexibility, oxygen permeability, and self-healing properties. PDMS, however, has some significant drawbacks. PDMS endures unacceptably high levels of nonspecific protein fouling...

journal_title：Biomacromolecules

authors： Keefe AJ,Brault ND,Jiang S

更新日期：2012-05-14 00:00:00

abstract：:The oxidation reaction of regenerated cellulose fibers mediated by N-hydroxyphthalimide (NHPI) and various cocatalysts at room temperature for different time intervals and various amounts of low concentration sodium hypochlorite solution has been investigated to produce oxidized cellulose (OC), a biocompatible and bio...

journal_title：Biomacromolecules

authors： Coseri S,Nistor G,Fras L,Strnad S,Harabagiu V,Simionescu BC

更新日期：2009-08-10 00:00:00

abstract：:Periodic patterns resembling spirals were observed to form spontaneously upon unassisted cooling of d-glucaric acid- and d-galactaric acid-based polyamide solutions in N-methyl-N-morpholine oxide (NMMO) monohydrate. Similar observations were made in d-galactaric acid-based polyamide/ionic liquid (IL) solutions. The mo...

journal_title：Biomacromolecules

authors： Rosu C,Russo PS,Daly WH,Cueto R,Pople JA,Laine RA,Negulescu II

更新日期：2015-09-14 00:00:00

abstract：:The intermolecular distributions of amide groups within two commercial LMA pectins was studied after removal of the methyl esters followed by fractionation of the different populations by anion exchange chromatography. The populations obtained had almost equal degrees of amidation while the values of the degree of blo...

journal_title：Biomacromolecules

authors： Guillotin SE,Mey N,Ananta E,Boulenguer P,Schols HA,Voragen AG

更新日期：2006-06-01 00:00:00

abstract：:An increase in hyaluronan (HA) synthesis, cellular uptake, and metabolism occurs during the remodeling of tissue microenvironments following injury and during disease processes such as cancer. We hypothesized that multimodality HA-based probes selectively target and detectably accumulate at sites of high HA metabolism...

journal_title：Biomacromolecules

authors： Veiseh M,Breadner D,Ma J,Akentieva N,Savani RC,Harrison R,Mikilus D,Collis L,Gustafson S,Lee TY,Koropatnick J,Luyt LG,Bissell MJ,Turley EA

更新日期：2012-01-09 00:00:00

abstract：:Minimization of drug side effects is a hallmark of advanced targeted therapy. Herein we describe the synthesis of polysaccharide-based nanocapsules prepared from furcellaran and chitosan via layer-by-layer deposition using electrostatic interaction. Using doxorubicin as a model drug, prepared nanocapsules showed excel...

journal_title：Biomacromolecules

authors： Milosavljevic V,Jamroz E,Gagic M,Haddad Y,Michalkova H,Balkova R,Tesarova B,Moulick A,Heger Z,Richtera L,Kopel P,Adam V

更新日期：2020-02-10 00:00:00

abstract：:A combination of chemo-photodynamic therapy has been manifested as a promising strategy for efficient cancer treatment due to the enhanced therapeutic efficacy. Here, we designed doxorubicin (DOX)-loaded photoresponsive micelles (DPRMs) based on a combination of chlorin e6 (Ce6) and lipoic acid (LA) conjugated methoxy...

journal_title：Biomacromolecules

authors： Kim DH,Hwang HS,Na K

更新日期：2018-08-13 00:00:00

abstract：:Introducing exogenous genes into plant cells is essential for a wide range of applications in agriculture and plant biotechnology fields. Cationic peptide carriers with cell-penetrating and DNA-binding domains successfully deliver exogenous genes into plants. However, their cell-penetrating activity may be attenuated ...

journal_title：Biomacromolecules

authors： Miyamoto T,Tsuchiya K,Numata K

更新日期：2019-02-11 00:00:00

abstract：:Poly(L-lactide)-based microspheres having cationic or anionic surfaces were prepared using polydepsipeptide-block-poly(L-lactide)s as surfactants. Polydepsipeptide-block-poly(L-lactide)s having amino or carboxylic acid groups on their side chains were synthesized through anionic ring-opening polymerizations of L-lacti...

journal_title：Biomacromolecules

authors： Ouchi T,Toyohara M,Arimura H,Ohya Y

更新日期：2002-09-01 00:00:00

abstract：:Gene therapy is rapidly regaining traction in terms of research activity and investment across the globe, with clear potential to revolutionize medicine and tissue regeneration. Viral vectors remain the most commonly utilized gene delivery vehicles, due to their high efficiency, however, they are acknowledged to have ...

journal_title：Biomacromolecules

authors： Wong LY,Xia B,Wolvetang E,Cooper-White J

更新日期：2018-02-12 00:00:00

abstract：:Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens. Here we report on a generic polymer-protein ligation strategy to formulate protein antigens into reversible polymeric conjugates for ...

journal_title：Biomacromolecules

authors： Lybaert L,Vanparijs N,Fierens K,Schuijs M,Nuhn L,Lambrecht BN,De Geest BG

更新日期：2016-03-14 00:00:00

abstract：:Phase separation mechanisms and kinetics were studied using small-angle light scattering in a gelatin/maltodextrin system where phase separation could be studied in both liquid and gelled states. Nucleation and growth or spinodal decomposition occurred, depending on the quench depth. The transition between the two mec...

journal_title：Biomacromolecules

authors： Butler MF

更新日期：2002-07-01 00:00:00

abstract：:To provide for prolonged, site-specific delivery of basic fibroblast growth factor (bFGF) to the grafted skin in a convenient manner, biodegradable chitosan-gelatin microspheres containing bFGF were fabricated and incorporated into a porous chitosan-gelatin scaffold in this study. The microspheres are an integral part...

journal_title：Biomacromolecules

authors： Liu H,Fan H,Cui Y,Chen Y,Yao K,Goh JC

更新日期：2007-05-01 00:00:00