Altered Thermal and Mechanical Properties of Spruce Galactoglucomannan Films Modified with an Etherification Reaction.

abstract：:Multifunctional cellulose nanocrystals have been synthesized and applied as a new type of glyconanomaterial in lectin binding and bacterial imaging. The cellulose nanocrystals were prepared by TEMPO-mediated oxidation and acidic hydrolysis, followed by functionalization with a quinolone fluorophore and carbohydrate li...

journal_title：Biomacromolecules

authors： Zhou J,Butchosa N,Jayawardena HS,Park J,Zhou Q,Yan M,Ramström O

更新日期：2015-04-13 00:00:00

abstract：:The need for thermosets from renewable resources is continuously increasing to find eco-friendly alternatives to petroleum-derived materials. Products obtained from biomass have shown to play an important role in this challenge. Here, we present the structural characterization of new biobased thermosets made of humins...

journal_title：Biomacromolecules

authors： Cantarutti C,Dinu R,Mija A

更新日期：2020-02-10 00:00:00

abstract：:A dual-targeted siRNA nanocarrier has been synthesized and validated that is selectively activated in environments where there is colocalization of two breast cancer hallmarks, elevated matrix metalloproteinase (MMP) activity and folate receptor overexpression. This siRNA nanocarrier is self-assembled from two polymer...

journal_title：Biomacromolecules

authors： Li H,Miteva M,Kirkbride KC,Cheng MJ,Nelson CE,Simpson EM,Gupta MK,Duvall CL,Giorgio TD

更新日期：2015-01-12 00:00:00

abstract：:Multicomponent poly(ethylene glycol) (PEG) brushes (i.e., ≥ 2 adjacent PEG brushes) can be used to engineer culture substrates with microscale, nonfouling regions decorated with covalently immobilized ligands that mediate biospecific interactions. However, synthesizing such brushes with orthogonal immobilization chemi...

journal_title：Biomacromolecules

authors： Sha J,Lippmann ES,McNulty J,Ma Y,Ashton RS

更新日期：2013-09-09 00:00:00

abstract：:A His-tagged coiled coil stem loop peptide with stable secondary structure was designed and biosynthesized. A series of oligopeptides related to the EBV envelope glycoprotein 350/220 N-terminal nonapeptide as potential CD21 receptor-binding epitopes were engineered into the loop region of the peptide scaffold. It was ...

journal_title：Biomacromolecules

authors： Tang A,Kopecek J

更新日期：2002-05-01 00:00:00

abstract：:On-line size-exclusion chromatography monitoring of potato phosphorylase catalyzed amylose synthesis--starting from alpha-D-glucose-1-P and maltohexaose--revealed rather monodisperse amylose populations. In the presence of lipids, amylose-lipid complexes spontaneously formed and precipitated. They were recovered by ce...

journal_title：Biomacromolecules

authors： Gelders GG,Goesaert H,Delcour JA

更新日期：2005-09-01 00:00:00

abstract：:Hydrogels are attractive materials for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. Recent advances in organic and polymer chemistry, bioengineering and nanotechnology have resulted in several new developments in the field of hydro...

journal_title：Biomacromolecules

authors： Buwalda SJ,Vermonden T,Hennink WE

更新日期：2017-02-13 00:00:00

abstract：:Gastric mucin, a high molecular weight glycoprotein, is responsible for providing the gel-forming properties and protective function of the gastric mucus layer. Bulk rheology measurements in the linear viscoelastic regime show that gastric mucin undergoes a pH-dependent sol-gel transition from a viscoelastic solution ...

journal_title：Biomacromolecules

authors： Celli JP,Turner BS,Afdhal NH,Ewoldt RH,McKinley GH,Bansil R,Erramilli S

更新日期：2007-05-01 00:00:00

abstract：:Surface pressure isotherms and structural and surface dilatational properties of three hydroxypropylmethycelluloses (HPMCs, called E4M, E50LV, and F4M) adsorbed films at the air-water interface were determined. In this work we present evidence that HPMC molecules are able to diffuse and saturate the air-water interfac...

journal_title：Biomacromolecules

authors： Pérez OE,Sánchez CC,Rodríguez Patino JM,Pilosof AM

更新日期：2006-01-01 00:00:00

abstract：:Orb-weaving spider silk fibers are assembled from very large, highly repetitive proteins. The repeated segments contain, in turn, short, simple, and repetitive amino acid motifs that account for the physical and mechanical properties of the assembled fiber. Of the six orb-weaver silk fibroins, the piriform silk that m...

journal_title：Biomacromolecules

authors： Perry DJ,Bittencourt D,Siltberg-Liberles J,Rech EL,Lewis RV

更新日期：2010-11-08 00:00:00

abstract：:Poor cell survival in vitro and in vivo is one of the key challenges in tissue engineering. Prosurvival therapeutic proteins, such as insulin-like growth factor-1 (IGF-1), can promote cell viability but require controlled delivery systems due to their short half-lives and rapid clearance. Biocompatible materials are c...

journal_title：Biomacromolecules

authors： Parker J,Mitrousis N,Shoichet MS

更新日期：2016-02-08 00:00:00

abstract：:Biocompatible photoresponsive materials are of interest for targeted drug delivery, tissue engineering, 2D and 3D protein patterning, and other biomedical applications. We prepared light degradable hydrogels using a natural alginate polysaccharide cross-linked with iron(III) cations. The "hard" iron(III) cations used ...

journal_title：Biomacromolecules

authors： Narayanan RP,Melman G,Letourneau NJ,Mendelson NL,Melman A

更新日期：2012-08-13 00:00:00

abstract：:Gelatin microspheres are well-known for their capacity to release growth factors in a controlled manner, but gelatin microspheres do not calcify in the absence of so-called bioactive substances that induce deposition of calcium phosphate (CaP) bone mineral. This study has investigated if CaP nanocrystals can be incorp...

journal_title：Biomacromolecules

authors： Leeuwenburgh SC,Jo J,Wang H,Yamamoto M,Jansen JA,Tabata Y

更新日期：2010-10-11 00:00:00

abstract：:Oligopeptide hydrogels are emerging as useful matrices for cell culture with commercial products on the market, but L-oligopeptides are labile to proteases. An obvious solution is to create D-oligopeptide hydrogels, which lack enzymatic recognition. However, D-oligopeptide matrices do not support cell growth as well a...

journal_title：Biomacromolecules

authors： Hyland LL,Twomey JD,Vogel S,Hsieh AH,Yu YB

更新日期：2013-02-11 00:00:00

abstract：:Chitosan hydrogel microspheres were obtained by cross-linking chitosan in its inverse emulsion using genipin as cross-linker. The genipin-cross-linked chitosan microspheres (ChGp) swell significantly in water at pH values below 6.5 and shrink to a smaller extent at pH values above 6.5. ChGp microspheres bind heparin i...

journal_title：Biomacromolecules

authors： Kamiński K,Zazakowny K,Szczubiałka K,Nowakowska M

更新日期：2008-11-01 00:00:00

abstract：:The controlled delivery of growth factors is a very challenging task because many different issues have to be addressed to develop the best suited system. A wide range of approaches have been employed for the controlled delivery of growth factors by hydrogels. Direct loading, electrostatic interaction, covalent bindin...

journal_title：Biomacromolecules

authors： Silva AK,Richard C,Bessodes M,Scherman D,Merten OW

更新日期：2009-01-12 00:00:00

abstract：:Biopolymers bearing hydrophobic side-chains, such as hydrophobically modified chitosan (hmC), can connect liposomes into a gel network via hydrophobic interactions. In this paper, we show that such liposome gels possess an attractive combination of properties for certain drug delivery applications. Their shear-thinnin...

journal_title：Biomacromolecules

authors： Lee JH,Oh H,Baxa U,Raghavan SR,Blumenthal R

更新日期：2012-10-08 00:00:00

abstract：:A recombinant silk-elastin-like protein copolymer SELP-47K containing tandemly repeated amino acid sequence blocks from silk, GAGAGS, and elastin, GVGVP, was fabricated into microdiameter fibers using a wet-spinning technique. Raman spectral analysis revealed the formation of antiparallel beta-sheet crystals of the si...

journal_title：Biomacromolecules

authors： Qiu W,Teng W,Cappello J,Wu X

更新日期：2009-03-09 00:00:00

abstract：:A series of structurally diverse polymers, containing either peptide or vinyl-derived backbones, was tested for ice recrystallization inhibition activity, which is commonly associated with antifreeze (glyco)proteins. It was revealed that only polymers bearing hydroxyl groups in the side chain could inhibit ice growth....

journal_title：Biomacromolecules

authors： Gibson MI,Barker CA,Spain SG,Albertin L,Cameron NR

更新日期：2009-02-09 00:00:00

abstract：:Tethering drug substances to a gel network is an effective way of controlling the release kinetics of hydrogel-based drug delivery systems. Here, we report on in situ forming, biodegradable hydrogels that allow for the covalent attachment of peptides or proteins. Hydrogels were prepared by step-growth polymerization o...

journal_title：Biomacromolecules

authors： Brandl F,Hammer N,Blunk T,Tessmar J,Goepferich A

更新日期：2010-02-08 00:00:00

abstract：:To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers...

journal_title：Biomacromolecules

authors： Lligadas G,Enayati M,Grama S,Smail R,Sherman SE,Percec V

更新日期：2017-08-14 00:00:00

abstract：:Fibrin sealants are a type of soft tissue adhesive that employs biochemical reactions from the late stages of the blood coagulation cascade. Intrinsic to these adhesives are a structural protein and a transglutaminase crosslinking enzyme. We are investigating an alternative biomimetic adhesive based on gelatin and a c...

journal_title：Biomacromolecules

authors： McDermott MK,Chen T,Williams CM,Markley KM,Payne GF

更新日期：2004-07-01 00:00:00

abstract：:For efficient reversal of multidrug resistance (MDR) in chemotherapy for breast cancer, multifunctional self-assembled nanoparticles (MSN) based on a new amphiphilic copolymer consisting of bioreducible poly[bis(2-hydroxylethyl)-disulfide-diacrylate-β-tetraethylenepentamine] and polycaprolactone (PBD-PCL) were constru...

journal_title：Biomacromolecules

authors： Yin Q,Shen J,Zhang Z,Yu H,Chen L,Gu W,Li Y

更新日期：2013-07-08 00:00:00

abstract：:Hydrogels derived from resilin-like polypeptides (RLPs) have shown outstanding mechanical resilience and cytocompatibility; expanding the versatility of RLP-based materials via conjugation with other polypeptides and polymers would offer great promise in the design of a range of materials. Here, we present an investig...

journal_title：Biomacromolecules

authors： McGann CL,Akins RE,Kiick KL

更新日期：2016-01-11 00:00:00

abstract：:A major challenge in drug delivery is the internalization through the apical plasma membrane of the polarized epithelial cells lining organs facing the external environment, e.g., lungs and the gastrointestinal tract. The reduced permeation of drugs entering through this pathway is in part due to the mucosal barrier a...

journal_title：Biomacromolecules

authors： Harush-Frenkel O,Rozentur E,Benita S,Altschuler Y

更新日期：2008-02-01 00:00:00

abstract：:To devise a sensitive cellulase assay based on substrates having most of the physical characteristics of native cellulose, 5-(4,6-dichlorotriazinyl)aminofluorescein (DTAF) was used as a grafting agent to prepare suspensions of fluorescent microfibrils from bacterial cellulose. These suspensions were digested by a seri...

journal_title：Biomacromolecules

authors： Helbert W,Chanzy H,Husum TL,Schülein M,Ernst S

更新日期：2003-05-01 00:00:00

abstract：:Self-assembly in aqueous solution of two oppositely charged globular proteins, hen egg white lysozyme (LYS) and bovine calcium-depleted α-lactalbumin (apo α-LA), was investigated at pH 7.5. The aggregation rate of equimolar mixtures of the two proteins was determined using static and dynamic light scattering as a func...

journal_title：Biomacromolecules

authors： Salvatore D,Croguennec T,Bouhallab S,Forge V,Nicolai T

更新日期：2011-05-09 00:00:00

abstract：:Chitosan is a linear cationic biopolymer composed of glucosamine and N-acetyl-glucosamine that is only soluble in acidic aqueous solutions and precipitates when neutralized. However, it was recently discovered that chitosan dissolved in solutions containing glycerol phosphate was soluble at near neutral pH and produce...

journal_title：Biomacromolecules

authors： Filion D,Lavertu M,Buschmann MD

更新日期：2007-10-01 00:00:00

abstract：:Ambidextrous supergelators are developed through structure-gelation screening of rationally designed cyclic dipeptides (CDPs). The organo- and hydrogels of CDPs were thoroughly characterized by their minimal gelation concentration (MGC) for organic and aqueous solvents, thermal stability (Tg), and viscoelastic propert...

journal_title：Biomacromolecules

authors： Manchineella S,Murugan NA,Govindaraju T

更新日期：2017-11-13 00:00:00

abstract：:Dynamic mechanical properties of aqueous solutions of hydroxypropyl methyl cellulose (HPMC) were investigated using oscillatory shear measurements. The structure was investigated with light scattering. A systematic investigation of the frequency dependence of the shear moduli showed that HPMC forms two distinct interp...

journal_title：Biomacromolecules

authors： Shahin A,Nicolai T,Benyahia L,Tassin JF,Chassenieux C

更新日期：2014-01-13 00:00:00