Photoresponsive Micelle-Incorporated Doxorubicin for Chemo-Photodynamic Therapy to Achieve Synergistic Antitumor Effects.

abstract：:Nature shows excellent control over the mechanics of fibrous hydrogels by assembling protein fibers into bundles of well-defined dimensions. Yet, obtaining artificial materials displaying controlled bundling remains a challenge. Here, we developed genetically engineered protein-based polymers functionalized with hepar...

journal_title：Biomacromolecules

authors： Włodarczyk-Biegun MK,Slingerland CJ,Werten MW,van Hees IA,de Wolf FA,de Vries R,Stuart MA,Kamperman M

更新日期：2016-06-13 00:00:00

abstract：:Peptide RATEA16 spontaneously self-assembled into higher-order nanofiber hydrogels with extremely high water content (>99.5% (wt/vol)) under physiological condition. The hydrogels could undergo pH-reversible transitions from viscous solution to elastic hydrogel and to precipitate. The supramolecular self-assembly and ...

journal_title：Biomacromolecules

authors： Zhao Y,Yokoi H,Tanaka M,Kinoshita T,Tan T

更新日期：2008-06-01 00:00:00

abstract：:Enzymatic adsorption and degradation of three types of aliphatic polyester films and two types of polyolefin films by the extracellular PHB depolymerase from Alcaligenes faecalis T1 have been studied by using a quartz crystal microbalance (QCM) technique. Hydrolysis of poly[(R)-3-hydroxybutyrate] was quantitatively fo...

journal_title：Biomacromolecules

authors： Yamashita K,Aoyagi Y,Abe H,Doi Y

更新日期：2001-04-01 00:00:00

abstract：:We described the preparation of the glycol chitosan/heparin immobilized iron oxide nanoparticles (composite NPs) as a magnetic resonance imaging agent with a tumor-targeting characteristic. The iron oxide nanoseeds used clinically as a magnetic resonance imaging agent were immobilized into the glycol chitosan/heparin ...

journal_title：Biomacromolecules

authors： Yuk SH,Oh KS,Cho SH,Lee BS,Kim SY,Kwak BK,Kim K,Kwon IC

更新日期：2011-06-13 00:00:00

abstract：:The coefficient of thermal expansion (CTE) of cellulose nanocrystal (CNC) films was characterized using novel experimental techniques complemented by molecular simulations. The characteristic birefringence exhibited by CNC films was utilized to calculate the in-plane CTE of self-organized and shear-oriented self-stand...

journal_title：Biomacromolecules

authors： Diaz JA,Wu X,Martini A,Youngblood JP,Moon RJ

更新日期：2013-08-12 00:00:00

abstract：:We demonstrate the formation of polyethylene glycol (PEG) based hydrogels via oxime ligation and the photoinitiated thiol-ene 3D patterning of peptides within the hydrogel matrix postgelation. The gelation process and final mechanical strength of the hydrogels can be tuned using pH and the catalyst concentration. The ...

journal_title：Biomacromolecules

authors： Lin F,Yu J,Tang W,Zheng J,Defante A,Guo K,Wesdemiotis C,Becker ML

更新日期：2013-10-14 00:00:00

abstract：:A variety of natural polymers and proteins are considered to be 3D cell culture structures able to mimic the extracellular matrix (ECM) to promote bone tissue regeneration. Pectin, a natural polysaccharide extracted from the plant cell walls and having a chemical structure similar to alginate, provides interesting pro...

journal_title：Biomacromolecules

authors： Munarin F,Guerreiro SG,Grellier MA,Tanzi MC,Barbosa MA,Petrini P,Granja PL

更新日期：2011-03-14 00:00:00

abstract：:Molecular dynamics (MD) simulations have been applied to study the interactions between hydrophobic and hydrophilic faces of ordered cellulose chains and a single layer of graphene in explicit aqueous solvent. The hydrophobic cellulose face is predicted to form a stable complex with graphene. This interface remains so...

journal_title：Biomacromolecules

authors： Alqus R,Eichhorn SJ,Bryce RA

更新日期：2015-06-08 00:00:00

abstract：:Bone fractures constitute a major cause of morbidity and mortality especially in the elderly. Complications associated with osteoporosis drugs and the age of the patient slow bone turnover and render such fractures difficult to heal. Increasing the speed of fracture repair by administration of a fracture-targeted bone...

journal_title：Biomacromolecules

authors： Low SA,Galliford CV,Yang J,Low PS,Kopeček J

更新日期：2015-10-12 00:00:00

abstract：:Semicrystalline, thermoresponsive poly(2-isopropyl-2-oxazoline) (PIPOx) layers covalently bonded to glass or silica wafers were obtained via the surface-termination of the living polymer chains. Polymer solutions in acetonitrile were exposed to 50 °C for various time periods and were poured onto the functionalized sol...

journal_title：Biomacromolecules

authors： Oleszko N,Wałach W,Utrata-Wesołek A,Kowalczuk A,Trzebicka B,Klama-Baryła A,Hoff-Lenczewska D,Kawecki M,Lesiak M,Sieroń AL,Dworak A

更新日期：2015-09-14 00:00:00

abstract：:The application of nanoparticles comprising amphiphilic block copolymers for the delivery of drugs is a subject of great interest as they hold promise for more effective and selective therapies. In order to achieve this ambition, it is of critical importance to develop our understanding of the self-assembly mechanisms...

journal_title：Biomacromolecules

authors： Ridolfo R,Arends JJ,van Hest JCM,Williams DS

更新日期：2020-06-08 00:00:00

abstract：:As a means to stimulate wound healing, a hollow fiber membrane system might be placed within a wound bed to provide local and externally regulated controlled delivery of regenerative factors. After sufficient healing, it would be desirable to triggerably degrade these fibers as opposed to pulling them out. Accordingly...

journal_title：Biomacromolecules

authors： Fu HL,Hong Y,Little SR,Wagner WR

更新日期：2014-08-11 00:00:00

abstract：:To broaden the application scope of lactic acid polymers, a new miniemulsion of poly(alkyl methacrylate-graft-lactic acid)s has been developed. The graft copolymer synthesis was based on a poly(lactic acid) macromonomer having a methacryloyl polymerizable group. The macromonomer and a comonomer of n-butyl methacrylate...

journal_title：Biomacromolecules

authors： Ishimoto K,Arimoto M,Ohara H,Kobayashi S,Ishii M,Morita K,Yamashita H,Yabuuchi N

更新日期：2009-10-12 00:00:00

abstract：:The development of large-scale suspension cell cultures using microcarriers has long been a focus of attention in the fields of pharmacy and biotechnology. Previously, we developed cell-detachable microcarriers based on temperature-responsive poly(N-isopropylacrylamide) (PIPAAm)-grafted beads, on which adhering cells ...

journal_title：Biomacromolecules

authors： Tamura A,Nishi M,Kobayashi J,Nagase K,Yajima H,Yamato M,Okano T

更新日期：2012-06-11 00:00:00

abstract：:The dynamics of bacterial colonies is complex in nature because it correlates the behavior of numerous individual cells in space and time and is characterized by emergent properties such as virulence or antibiotics resistance. Because there is no clear-cut evidence that periodic swarming of P. mirabilis colonies is ru...

journal_title：Biomacromolecules

authors： Lahaye E,Aubry T,Kervarec N,Douzenel P,Sire O

更新日期：2007-04-01 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:The unsatisfied results of cancer therapy are caused by many issues and metastasis of cancer cells is one of the major challenge. It has been reported that inhibiting the SDF1/CXCR4 interaction can significantly reduce the metastasis of breast cancer cells to regional lymph nodes and lung. Herein, a nanogel system equ...

journal_title：Biomacromolecules

authors： Zhang F,Gong S,Wu J,Li H,Oupicky D,Sun M

更新日期：2017-06-12 00:00:00

abstract：:Placing a physical barrier between the injured site and the adjacent tissues is a very common and highly effective approach to prevent abdominal adhesions in these days. A biodegradable trilayered barrier was fabricated to prevent formation of abdominal adhesions, in which a poly(lactide-co-glycolide)/poly(lactide)-b-...

journal_title：Biomacromolecules

authors： Xia Q,Liu Z,Wang C,Zhang Z,Xu S,Han CC

更新日期：2015-09-14 00:00:00

abstract：:Glycerol derivatives of cutin and suberin monomers were synthesized by acid catalysis. Their dispersion in an aqueous solution was examined by phase contrast microscopy, neutron scattering, and solid state NMR. It is shown that the phase behavior strongly depends on the nature of the derivatives forming either lumps o...

journal_title：Biomacromolecules

authors： Douliez JP,Barrault J,Jerome F,Heredia A,Navailles L,Nallet F

更新日期：2005-01-01 00:00:00

abstract：:This study describes the formulation and physicochemical characterization of poly(acrylic acid) (PAA) organogels, designed as bioactive implants for improved treatment of infectious diseases of the oral cavity. Organogels were formulated containing a range of concentrations of PAA (3-10% w/w) and metronidazole (2 or 5...

journal_title：Biomacromolecules

authors： Jones DS,Muldoon BC,Woolfson AD,Andrews GP,Sanderson FD

更新日期：2008-02-01 00:00:00

abstract：:Biomimetic nanoengineering built through integrating the specific cell membrane with artificially synthetic nanomedicines represents one of the most promising directions for the actualization of personalized therapy. For addressing the technical hurdle against the development of this biomimetic technology, the present...

journal_title：Biomacromolecules

authors： Zhu J,Zhang M,Zheng D,Hong S,Feng J,Zhang XZ

更新日期：2018-06-11 00:00:00

abstract：:The aim of this work was to evaluate the potential of INVITE-based nanomicelles, an amphiphilic polymer constituted by inulin (INU) and vitamin E (VITE), as a platform for improving the biopharmaceutical properties of hydrophobic drugs. For this purpose, curcumin was selected as a model and curcumin-INVITE nanomicelle...

journal_title：Biomacromolecules

authors： Tripodo G,Pasut G,Trapani A,Mero A,Lasorsa FM,Chlapanidas T,Trapani G,Mandracchia D

更新日期：2015-02-09 00:00:00

abstract：:In the fields of surgery and regenerative medicine, it is crucial to understand the interactions of proteins with the biomaterials used as implants. Protein adsorption directly influences cell-material interactions in vivo and, as a result, regulates, for example, cell adhesion on the surface of the implant. Therefore...

journal_title：Biomacromolecules

authors： Schönwälder SM,Bally F,Heinke L,Azucena C,Bulut ÖD,Heißler S,Kirschhöfer F,Gebauer TP,Neffe AT,Lendlein A,Brenner-Weiß G,Lahann J,Welle A,Overhage J,Wöll C

更新日期：2014-07-14 00:00:00

abstract：:A well-defined fluorescent conjugated polyfluorene with pendant lactopyranosyl ligands was easily prepared through Cu(I)-catalyzed azide/alkyne "click" ligation and Suzuki coupling polymerization. As a fluorescent multivalent model system of glycoconjugates, the polymer was first used for studies of metal ion-mediated...

journal_title：Biomacromolecules

authors： Chen Q,Cui Y,Zhang TL,Cao J,Han BH

更新日期：2010-01-11 00:00:00

abstract：:Chitosan hydrogel microspheres were obtained by cross-linking chitosan in its inverse emulsion using genipin as cross-linker. The genipin-cross-linked chitosan microspheres (ChGp) swell significantly in water at pH values below 6.5 and shrink to a smaller extent at pH values above 6.5. ChGp microspheres bind heparin i...

journal_title：Biomacromolecules

authors： Kamiński K,Zazakowny K,Szczubiałka K,Nowakowska M

更新日期：2008-11-01 00:00:00

abstract：:Glycosaminoglycan (GAG)-protein binding governs critically important signaling events in living matter. Aiming at a quantitative analysis of the involved processes, we herein present a thermodynamic study of the interaction of the model GAG heparin and lysozyme in aqueous solution. Heparin is a highly charged linear p...

journal_title：Biomacromolecules

authors： Walkowiak JJ,Ballauff M,Zimmermann R,Freudenberg U,Werner C

更新日期：2020-11-09 00:00:00

abstract：:A wool fiber sample was submitted to chemical-free steam explosion in view of potential exploitation of keratin-based industrial and farm wastes. Fiber keratin was converted into a dark-yellow sludge that was submitted to phase separation by filtration, centrifugation, and precipitation of the soluble materials from t...

journal_title：Biomacromolecules

authors： Tonin C,Zoccola M,Aluigi A,Varesano A,Montarsolo A,Vineis C,Zimbardi F

更新日期：2006-12-01 00:00:00

abstract：:Control of the photoluminescence properties of cellulose is conducted by introduction of conducting polymers including fluorene (F) and 3-hexylthiophene (3HT) on cellulose surface through FeCl3 oxidative polymerization. The UV-vis absorption peak of cellulose grafted with the 3-hexylthiophene and fluorene copolymer wa...

journal_title：Biomacromolecules

authors： Phung Hai TA,Sugimoto R

更新日期：2017-12-11 00:00:00

abstract：:A multiple targeted drug carrying bilayer membrane for preventing an abdominal adhesion is prepared by electrospinning. Two bioactive drugs were successfully incorporated into this bilayer membrane and can be independently released from nanofibrous scaffolds without losing structural integrity and functionality of the...

journal_title：Biomacromolecules

authors： Wang H,Li M,Hu J,Wang C,Xu S,Han CC

更新日期：2013-04-08 00:00:00

abstract：:The interaction between DNA and different types of amino acid-based cationic surfactants was investigated. Particular attention was directed to determine the extent of influence of surfactant head-group geometry toward tuning the interaction behavior of these surfactants with DNA. An overview is obtained by gel retard...

journal_title：Biomacromolecules

authors： Jadhav V,Maiti S,Dasgupta A,Das PK,Dias RS,Miguel MG,Lindman B

更新日期：2008-07-01 00:00:00