New design of helix bundle peptide-polymer conjugates.

abstract：:Numerous catechol-containing polymers, including biodegradable polymers, are currently heavily discussed for modern biomaterials. However, there is no report combining poly(phosphoester)s (PPEs) with catechols. Adhesive PPEs have been prepared via acyclic diene metathesis polymerization. A novel acetal-protected catec...

journal_title：Biomacromolecules

authors： Becker G,Ackermann LM,Schechtel E,Klapper M,Tremel W,Wurm FR

更新日期：2017-03-13 00:00:00

abstract：:Hydrogels are attractive materials for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. Recent advances in organic and polymer chemistry, bioengineering and nanotechnology have resulted in several new developments in the field of hydro...

journal_title：Biomacromolecules

authors： Buwalda SJ,Vermonden T,Hennink WE

更新日期：2017-02-13 00:00:00

abstract：:The leading cause of death in the United States is cardiovascular disease. The majority of these cases result from heart failure post-myocardial infarction (MI). We present data providing evidence for use of acetalated dextran (AcDex) microparticles as a delivery vehicle for therapeutics to the heart post-MI. We harne...

journal_title：Biomacromolecules

authors： Suarez S,Grover GN,Braden RL,Christman KL,Almutairi A

更新日期：2013-11-11 00:00:00

abstract：:New type of N-glycosylated peptides having periodic sequence of -[X-Gln(beta-D-GlcNAc)-Aib]- [X = L-Glu(OMe), L-Lys(Ac), L-Ala; Aib = alpha-aminoisobutyric acid] were synthesized by polymerization of glycosylated tripeptides with an active ester methods using Cl(-+)H(3)N-L-Glu(OMe)-Gln[beta-D-GlcNAc(Ac)(3)]-Aib-ONp (N...

journal_title：Biomacromolecules

authors： Takasu A,Horikoshi S,Hirabayashi T

更新日期：2005-07-01 00:00:00

abstract：:The SEC-MALS-QELS (size-exclusion chromatography equipped with multiangle light scattering and quasi-elastic light scattering detectors) method using lithium chloride/N,N-dimethylacetamide (LiCl/DMAc) and LiCl/1,3-dimethyl-2-imidazolidinone (LiCl/DMI) as mobile phases was applied to cellulose and cellulose tricarbanil...

journal_title：Biomacromolecules

authors： Yanagisawa M,Isogai A

更新日期：2005-05-01 00:00:00

abstract：:As a first step toward utilizing self-assembling peptide scaffolds to create tunable matrices for drug delivery, peptide RADAFI and RADAFII, containing the same amino acid composition but different positions of one phenylalanine residue, scaffolds were prepared for controlled release of chiral enantiomers. The release...

journal_title：Biomacromolecules

authors： Zhao Y,Tanaka M,Kinoshita T,Higuchi M,Tan T

更新日期：2009-12-14 00:00:00

abstract：:The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelat...

journal_title：Biomacromolecules

authors： Agulhon P,Robitzer M,David L,Quignard F

更新日期：2012-01-09 00:00:00

abstract：:Softwood and hardwood celluloses were oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation. The TEMPO-oxidized cellulose fibers were converted to transparent dispersions in water, which consisted of individual nanofibers 3-4 nm in width. Films were then prepared from the TEMPO-oxidized c...

journal_title：Biomacromolecules

authors： Fukuzumi H,Saito T,Iwata T,Kumamoto Y,Isogai A

更新日期：2009-01-12 00:00:00

abstract：:The interaction of polysaccharides with water has a critical impact on their biological function as well as their technological applications. We performed ellipsometry experiments at different relative humidities (RH) to measure the equilibrium swelling of ultrathin films of different polysaccharides: native and modif...

journal_title：Biomacromolecules

authors： Grossutti M,Dutcher JR

更新日期：2020-12-14 00:00:00

abstract：:Biobased poly(γ-butyrolactone) (PγBL) as a fully biodegradable and bioabsorbable biomaterial has shown superior properties compared to those of other aliphatic polyesters. It is of great importance to prepare amphiphilic block copolymer containing PγBL block to make ordered nano-objects for biomedical applications suc...

journal_title：Biomacromolecules

authors： Shen Y,Zhang J,Zhao Z,Zhao N,Liu F,Li Z

更新日期：2019-01-14 00:00:00

abstract：:Highly fluorescent N-substituted 1-cyanobenz[f]isoindole chitosans (CBI-CSs) with various degrees of N-substitution (DS) were synthesized by reacting chitosan (CS) with naphthalene-2,3-dicarboxaldehyde (NDA) in the presence of cyanide under mild acidic conditions. Introduction of 1-cyanobenz[f]isoindole moieties into ...

journal_title：Biomacromolecules

authors： Gonil P,Sajomsang W,Ruktanonchai UR,Na Ubol P,Treetong A,Opanasopit P,Puttipipatkhachorn S

更新日期：2014-08-11 00:00:00

abstract：:A comprehensive understanding of the mechanism by which type I collagen (Col) interacts with hydroxyapatite nanoparticles (Hap NPs) in aqueous solutions is a pivotal step for guiding the design of biologically relevant nanocomposites with controlled hierarchical structure. In this paper we use a variety of Hap NPs dif...

journal_title：Biomacromolecules

authors： Colaço E,Brouri D,Aissaoui N,Cornette P,Dupres V,Domingos RF,Lambert JF,Maisonhaute E,Kirat KE,Landoulsi J

更新日期：2019-12-09 00:00:00

abstract：:Hydrogel fibers that possessed a cell-adhesive surface and were degradable via enzymatic reactions were developed for fabricating tubular constructs with smooth muscle cell (SMC) and endothelial cell (EC) layers, similar to native blood vessels, in collagen gels. The fibers were prepared by soaking hydrogel fibers pre...

journal_title：Biomacromolecules

authors： Sakai S,Yamaguchi S,Takei T,Kawakami K

更新日期：2008-07-01 00:00:00

abstract：:A one-pot synthetic methodology for fabricating stimuli-responsive hemicellulose-based hydrogels was developed that consists of the in situ formation of magnetic iron oxide (Fe3O4) nanoparticles during the covalent cross-linking of O-acetyl-galactoglucomannan (AcGGM). The Fe3O4 nanoparticle content controlled the ther...

journal_title：Biomacromolecules

authors： Zhao W,Odelius K,Edlund U,Zhao C,Albertsson AC

更新日期：2015-08-10 00:00:00

abstract：:The short average service life of traditional dental composite restorative materials and increasing occurrence of secondary caries adjacent to composite restorations and sealants are necessitating the development of new, longer lasting compositions. Novel monomers and their polymers, reinforcing fillers, and adhesive ...

journal_title：Biomacromolecules

authors： Gonzalez-Bonet A,Kaufman G,Yang Y,Wong C,Jackson A,Huyang G,Bowen R,Sun J

更新日期：2015-10-12 00:00:00

abstract：:Oligosaccharides of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, and methyl cellulose were investigated by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The cellulose ether oligosaccharides were produced either by enzymatic depolymerization utilizing the purified family 5 endoglu...

journal_title：Biomacromolecules

authors： Momcilovic D,Schagerlöf H,Wittgren B,Wahlund KG,Brinkmalm G

更新日期：2005-09-01 00:00:00

abstract：:Textile chitosan fiber scaffolds were developed and tested in terms of biocompatibility for human bone marrow stromal cells (hBMSCs). A part of the scaffolds was further modified by coating with fibrillar collagen type I in order to biologize the surface. hBMSCs of two donors were used for cell culture experiments in ...

journal_title：Biomacromolecules

authors： Heinemann C,Heinemann S,Lode A,Bernhardt A,Worch H,Hanke T

更新日期：2009-05-11 00:00:00

abstract：:Polymer therapeutics, including polymeric drugs and polymer-protein conjugates, are clinically established as first-generation nanomedicines. Knowing that the coiled-coil peptide motif is fundamentally important in the regulation of many cellular and pathological processes, the aim of these studies was to examine the ...

journal_title：Biomacromolecules

authors： Deacon SP,Apostolovic B,Carbajo RJ,Schott AK,Beck K,Vicent MJ,Pineda-Lucena A,Klok HA,Duncan R

更新日期：2011-01-10 00:00:00

abstract：:Hyperbranched poly(amino ester)s containing tertiary amines in the core and primary, secondary, and tertiary amines in the periphery, respectively, were evaluated for DNA delivery in vitro. The same core structure facilitated the investigation on the effects of the terminal amine type on the properties of hyperbranche...

journal_title：Biomacromolecules

authors： Wu D,Liu Y,Jiang X,He C,Goh SH,Leong KW

更新日期：2006-06-01 00:00:00

abstract：:Ternary compatible blends of chitosan, poly(vinyl alcohol), and poly(lactic acid) were prepared by an oil-in-water (O/W) emulsion process. Solutions of chitosan in aqueous acetic acid, poly(vinyl alcohol) (PVA) in water, and poly(lactic acid) (PLA) in chloroform were blended with a high-shear mixer. PVA was used as an...

journal_title：Biomacromolecules

authors： Grande R,Carvalho AJ

更新日期：2011-04-11 00:00:00

abstract：:Ionic liquids (ILs) are composed only of ions. Of special interest to this review are those where at least one ion (the cation) is organic and whose melting points are below or not far above room temperature. ILs are designated as "green" solvents because they have extremely low vapor pressure, are non-inflammable, an...

journal_title：Biomacromolecules

authors： El Seoud OA,Koschella A,Fidale LC,Dorn S,Heinze T

更新日期：2007-09-01 00:00:00

abstract：:Natural selection has endorsed proteins with amazing structures and functionalities that cannot be matched by synthetic means, explaining the exponential interest in developing protein-based materials. Protein self-assembly allows fabricating complex supramolecular structures from relatively simple building blocks, a ...

journal_title：Biomacromolecules

authors： Wang W,Azizyan RA,Garro A,Kajava AV,Ventura S

更新日期：2020-10-12 00:00:00

abstract：:Bacterial cellulose (BC) is a polysaccharide known as a suitable matrix for proper wound healing. To improve this ability, BC was functionalized with silk sericin (SS) that has cytoprotective and mitogenic effects. The composites obtained by solution impregnation were stabilized by hydrogen bonds, and SS could be rele...

journal_title：Biomacromolecules

authors： Lamboni L,Li Y,Liu J,Yang G

更新日期：2016-09-12 00:00:00

abstract：:The polymerization of N-isopropylacrylamide (NIPAAm) with ionizable monomers results in pH-responsive lower critical solution temperature (LCST) polymer which works in an ionization-dependent manner. However, gradual ionization of the comonomer occurs at a broad pH range due to the electrostatic field generated by the...

journal_title：Biomacromolecules

authors： Muttaqien SE,Nomoto T,Takemoto H,Matsui M,Tomoda K,Nishiyama N

更新日期：2019-04-08 00:00:00

abstract：:Biomimetic nanocomposites and scaffolds hold the key to a wide range of biomedical applications. Here we show, for the first time, a facile scheme of cofibrillizing pathogenic and functional amyloid fibrils via gold nanoparticles (AuNPs) and their applications against amyloidogenesis. This scheme was realized by β-she...

journal_title：Biomacromolecules

authors： Javed I,Sun Y,Adamcik J,Wang B,Kakinen A,Pilkington EH,Ding F,Mezzenga R,Davis TP,Ke PC

更新日期：2017-12-11 00:00:00

abstract：:Chimeric DNA containing parallel (ps) and antiparallel (aps) duplex elements as well as poly-dC tracts were designed and synthesized. Oligonucleotide duplexes with ps chain orientation containing reverse Watson-Crick dA-dT base pairs and short d(C)2 tails are stabilized under slightly acidic conditions by hemiprotonat...

journal_title：Biomacromolecules

authors： Mei H,Budow S,Seela F

更新日期：2012-12-10 00:00:00

abstract：:A first attempt to attenuate the quorum sensing (QS) of a marine heterotroph microorganism, Vibrio fischeri , using signal molecule-sequestering polymers (SSPs) is presented. A set of rationally designed polymers with affinity toward a signal molecule of V. fischeri , N-(beta-ketocaproyl)-l-homoserine lactone (3-oxo-C...

journal_title：Biomacromolecules

authors： Piletska EV,Stavroulakis G,Karim K,Whitcombe MJ,Chianella I,Sharma A,Eboigbodin KE,Robinson GK,Piletsky SA

更新日期：2010-04-12 00:00:00

abstract：:Enzymatic ring-opening copolymerization of 5-benzyloxy-trimethylene carbonate (BTMC) and 1,4-dioxan-2-one (DON) was investigated for the first time. Immobilized porcine pancreas lipase (IPPL) on silica particles was selected to perform the copolymerization. A series of novel biodegradable copolymers with different com...

journal_title：Biomacromolecules

authors： He F,Jia HL,Liu G,Wang YP,Feng J,Zhuo RX

更新日期：2006-08-01 00:00:00

abstract：:Enzyme-responsive polypeptide vesicles have attracted considerable attention for precision theranostics because of their biocompatibility, biodegradability, and unique secondary conformation transition triggered by the catalytic actions of enzymes. These promising potentials of polypeptide vesicles could be limited in...

journal_title：Biomacromolecules

authors： Duan W,Ji S,Guan Y,Mu X,Fang S,Lu Y,Zhou X,Sun J,Li Z

更新日期：2020-12-14 00:00:00

abstract：:The objective of this study was to explore the use of reverse thermo-responsive (RTG) polymers for generating implants at their site of performance, following minimally invasive surgical procedures. Aiming at combining syringability and enhanced mechanical properties, a new family of injectable RTG-displaying polymers...

journal_title：Biomacromolecules

authors： Cohn D,Sosnik A,Garty S

更新日期：2005-05-01 00:00:00