Construction and assembly of chimeric DNA: oligonucleotide hybrid molecules composed of parallel or antiparallel duplexes and tetrameric i-motifs.

abstract：:This Article describes the synthesis and characterization of renewable self-adhesive coatings with tunable viscoelastic properties and equipped with well-defined amounts of carboxylic acid "sticker" groups with adhesion promoting characteristics. Hydroxyl-ended polyesters with various architectures (linear, branched) ...

journal_title：Biomacromolecules

authors： Vendamme R,Olaerts K,Gomes M,Degens M,Shigematsu T,Eevers W

更新日期：2012-06-11 00:00:00

abstract：:This work demonstrates a versatile and environmentally friendly route for the development of new orthogonal monomers that can be used for postfunctionalizable polymer networks. A monomer containing both vinyl ether (VE) and cyclic disulfide moieties was synthesized via enzyme catalysis under benign reaction conditions...

journal_title：Biomacromolecules

authors： Brännström S,Johansson M,Malmström E

更新日期：2019-03-11 00:00:00

abstract：:Oligonucleotide-spider silk conjugates can be placed on silicon wafers by complementary DNA strands, which are coupled chemically to the surface. Such specific immobilization of spider silk proteins allows the nucleation and guided growth of β-sheet-rich nanofibrils in the presence of phosphate ions on the surface. Ad...

journal_title：Biomacromolecules

authors： Molina A,Scheibel T,Humenik M

更新日期：2019-01-14 00:00:00

abstract：:Semicrystalline, thermoresponsive poly(2-isopropyl-2-oxazoline) (PIPOx) layers covalently bonded to glass or silica wafers were obtained via the surface-termination of the living polymer chains. Polymer solutions in acetonitrile were exposed to 50 °C for various time periods and were poured onto the functionalized sol...

journal_title：Biomacromolecules

authors： Oleszko N,Wałach W,Utrata-Wesołek A,Kowalczuk A,Trzebicka B,Klama-Baryła A,Hoff-Lenczewska D,Kawecki M,Lesiak M,Sieroń AL,Dworak A

更新日期：2015-09-14 00:00:00

abstract：:Amyloid-like fibrils are prepared from protein in the lab by controlled heat treatments, yet these must be further assembled to match the desirable mechanical and structural properties of biological fibers. Here, β-lactoglobulin fibrils were incorporated into poly(ethylene oxide) fibers of 40-180 nm diameter by electr...

journal_title：Biomacromolecules

authors： Chen D,Narayanan N,Federici E,Yang Z,Zuo X,Gao J,Fang F,Deng M,Campanella OH,Jones OG

更新日期：2020-07-13 00:00:00

abstract：:Binding human serum albumin (HSA) of three polyoxometalates (POMs) with the Wells-Dawson structure, alpha(2)-[P2W17O61]10- (abbreviated as alpha(2)-P2W17) and two of its metal-substituted derivatives, alpha(2)-[NiP2W17O61]8- and alpha(2)-[CuP2W17O61]8- (alpha(2)-P2W17Ni and alpha(2)-P2W17Cu, respectively) was studied ...

journal_title：Biomacromolecules

authors： Zhang G,Keita B,Craescu CT,Miron S,de Oliveira P,Nadjo L

更新日期：2008-03-01 00:00:00

abstract：:Mammalian synovial joints are extremely efficient lubrication systems reaching friction coefficient μ as low as 0.001 at high pressures (up to 100 atm) and shear rates (up to 10(6) to 10(7) Hz); however, despite much previous work, the exact mechanism responsible for this behavior is still unknown. In this work, we st...

journal_title：Biomacromolecules

authors： Seror J,Merkher Y,Kampf N,Collinson L,Day AJ,Maroudas A,Klein J

更新日期：2011-10-10 00:00:00

abstract：:The development of improved cryopreservative materials is necessary to enable complete recovery of living cells and tissue after frozen storage. Remarkably, poly(vinyl alcohol) (PVA) displays some of the same cryoprotective properties as many antifreeze proteins found in cold tolerant organisms. In particular, PVA is ...

journal_title：Biomacromolecules

authors： Burkey AA,Riley CL,Wang LK,Hatridge TA,Lynd NA

更新日期：2018-01-08 00:00:00

abstract：:Combining poly(ethylene glycol) (PEG) with sequence-defined peptides in PEG-peptide conjugates offers opportunities to realize next-generation drug formulation additives for overcoming undesired pharmacological profiles of difficult small molecule drugs. The tailored peptide segments provide sequence-specific, noncova...

journal_title：Biomacromolecules

authors： Wieczorek S,Schwaar T,Senge MO,Börner HG

更新日期：2015-10-12 00:00:00

abstract：:The polymerization of N-isopropylacrylamide (NIPAAm) with ionizable monomers results in pH-responsive lower critical solution temperature (LCST) polymer which works in an ionization-dependent manner. However, gradual ionization of the comonomer occurs at a broad pH range due to the electrostatic field generated by the...

journal_title：Biomacromolecules

authors： Muttaqien SE,Nomoto T,Takemoto H,Matsui M,Tomoda K,Nishiyama N

更新日期：2019-04-08 00:00:00

abstract：:The growing importance of biodegradable conducting polymers (CPs) have fueled the rapid development of this unique class of polymeric materials in recent years. Possessing both the electrical conductivity approaching those of metallic conductors and the biodegradability of biocompatible polymers, biodegradable CPs are...

journal_title：Biomacromolecules

authors： Kenry,Liu B

更新日期：2018-06-11 00:00:00

abstract：:Poor cell survival in vitro and in vivo is one of the key challenges in tissue engineering. Prosurvival therapeutic proteins, such as insulin-like growth factor-1 (IGF-1), can promote cell viability but require controlled delivery systems due to their short half-lives and rapid clearance. Biocompatible materials are c...

journal_title：Biomacromolecules

authors： Parker J,Mitrousis N,Shoichet MS

更新日期：2016-02-08 00:00:00

abstract：:A poly[(R)-3-hydroxybutyrate] (P(3HB))-degrading marine bacterium (strain NK-1, JCM10458) was isolated from the Pacific Ocean deep-sea floor (1165 m in depth) in Japan. The organism was a motile and Gram negative, aerobic, and rod-shaped bacterium, and its DNA had a guanine-plus-cytosine content of 57.7 mol%. On the b...

journal_title：Biomacromolecules

authors： Kasuya K,Mitomo H,Nakahara M,Akiba A,Kudo T,Doi Y

更新日期：2000-07-01 00:00:00

abstract：:Silk-elastin-like proteins (SELPs) have enormous potential for use as customizable biomaterials in numerous biomedical and materials applications, yet success in harnessing this potential has been limited by the lack of a commercially viable industrially relevant production process. We have developed a scalable fed-ba...

journal_title：Biomacromolecules

authors： Collins T,Barroca M,Branca F,Padrão J,Machado R,Casal M

更新日期：2014-07-14 00:00:00

abstract：:Dextrin, a glucose polymer with low molecular weight, was used to develop a fully resorbable hydrogel, without using chemical initiators. Dextrin was first oxidized (oDex) with sodium periodate and then cross-linked with adipic acid dihidrazide, a nontoxic cross-linking molecule. Furthermore, a new bidimensional compo...

journal_title：Biomacromolecules

authors： Molinos M,Carvalho V,Silva DM,Gama FM

更新日期：2012-02-13 00:00:00

abstract：:In this work, cell-responsive polysaccharide hydrogels were prepared by a simple procedure based on the sequential bioconjugation and cross-linking of the polysaccharide backbone with bioactive peptides and poly(ethylene glycol)-bis(thiol) (PEG-(SH)2), respectively. Using thiol-ene reactions, we successfully functiona...

journal_title：Biomacromolecules

authors： Jing J,Fournier A,Szarpak-Jankowska A,Block MR,Auzély-Velty R

更新日期：2015-03-09 00:00:00

abstract：:The manufacture of biodegradable materials from agricultural sources is a real challenge, because of environmental concerns and the need to make full use of resources. Cottonseed is an important protein source that could be used in nonfood applications, as a substitute for synthetic polymers. For the first time, the v...

journal_title：Biomacromolecules

authors： Grevellec J,Marquié C,Ferry L,Crespy A,Vialettes V

更新日期：2001-01-01 00:00:00

abstract：:Electrospun natural polymer membranes were fabricated from collagen or gelatin coated with a bioactive recombinant fragment of perlecan, a natural heparan sulfate proteoglycan. The electrospinning process allowed the facile processing of a three-dimensional, porous fibril (2-6 microm in diameter) matrix suitable for t...

journal_title：Biomacromolecules

authors： Casper CL,Yang W,Farach-Carson MC,Rabolt JF

更新日期：2007-04-01 00:00:00

abstract：:Hydrogels derived from resilin-like polypeptides (RLPs) have shown outstanding mechanical resilience and cytocompatibility; expanding the versatility of RLP-based materials via conjugation with other polypeptides and polymers would offer great promise in the design of a range of materials. Here, we present an investig...

journal_title：Biomacromolecules

authors： McGann CL,Akins RE,Kiick KL

更新日期：2016-01-11 00:00:00

abstract：:New pH-responsive polymersomes for active anticancer oligonucleotide delivery were prepared from triblock copolymers. The delivery systems were formed by two terminal hydrophilic blocks, PEG and polyglycerolmethacrylate (poly-GMA), and a central weakly basic block, polyimidazole-hexyl methacrylate (poly-ImHeMA), which...

journal_title：Biomacromolecules

authors： Gallon E,Matini T,Sasso L,Mantovani G,Armiñan de Benito A,Sanchis J,Caliceti P,Alexander C,Vicent MJ,Salmaso S

更新日期：2015-07-13 00:00:00

abstract：:In a previous study, we have reported chemical synthesis of novel aliphatic poly(butylene succinate-co-cyclic carbonate) P(BS-co-CC)s bearing various functionalizable carbonate building blocks, and this work will continue to present our new studies on their enzymatic degradation and in vitro cell biocompatibility assa...

journal_title：Biomacromolecules

authors： Yang J,Tian W,Li Q,Li Y,Cao A

更新日期：2004-11-01 00:00:00

abstract：:Electrospun biopolyelectrolyte nanofibers hold potential for use in a range of biomedical applications, but eliminating toxic chemicals involved in their production remains a key challenge. In this study, we successfully electrospun nanofibers from an aqueous complex coacervate solution composed of chitosan and hyalur...

journal_title：Biomacromolecules

authors： Sun J,Perry SL,Schiffman JD

更新日期：2019-11-11 00:00:00

abstract：:New type of N-glycosylated peptides having periodic sequence of -[X-Gln(beta-D-GlcNAc)-Aib]- [X = L-Glu(OMe), L-Lys(Ac), L-Ala; Aib = alpha-aminoisobutyric acid] were synthesized by polymerization of glycosylated tripeptides with an active ester methods using Cl(-+)H(3)N-L-Glu(OMe)-Gln[beta-D-GlcNAc(Ac)(3)]-Aib-ONp (N...

journal_title：Biomacromolecules

authors： Takasu A,Horikoshi S,Hirabayashi T

更新日期：2005-07-01 00:00:00

abstract：:Spiders have evolved a complex system of silk producing glands. Each of the glands produces silk with strength and elasticity tailored to its biological purpose. Sequence analysis of the major ampullate silk reveals four highly conserved concatenated blocks of amino acids: (GA) n , A n , GPGXX, and GGX. While the GPGX...

journal_title：Biomacromolecules

authors： Brooks AE,Stricker SM,Joshi SB,Kamerzell TJ,Middaugh CR,Lewis RV

更新日期：2008-06-01 00:00:00

abstract：:Recent findings suggest that visible light-promoted photooxidative processes mediated by sensitizers of appropriate chemical structure could represent a useful tool for properly addressing the problem of the increasing occurrence of infectious diseases caused by multiantibiotic-resistant microbial pathogens. The monoc...

journal_title：Biomacromolecules

authors： Ferro S,Jori G,Sortino S,Stancanelli R,Nikolov P,Tognon G,Ricchelli F,Mazzaglia A

更新日期：2009-09-14 00:00:00

abstract：:The structure of the Ca--alginate junction zones was investigated with X-ray scattering on gels prepared with different methods. Fiber diffraction reveals the popular egg-box model may not be the only possible structure for the junction zones. The (001) reflection, which should be extinguished due to 2/1 helical confo...

journal_title：Biomacromolecules

authors： Li L,Fang Y,Vreeker R,Appelqvist I,Mendes E

更新日期：2007-02-01 00:00:00

abstract：:Reversible addition-fragmentation chain transfer (RAFT) radical polymerization, mediated by 4-cyanopentanoic acid dithiobenzoate and 4,4'-azobis(4-cyanovaleric acid) (V-501) in water at 70 degrees C, of biocompatible 2-(methacryloyloxy)ethyl phosphorylcholine (MPC) yields a macro-chain transfer agent (CTA) that was em...

journal_title：Biomacromolecules

authors： Yu B,Lowe AB,Ishihara K

更新日期：2009-04-13 00:00:00

abstract：:Poly((N-vinylpyrrolidone)-block-poly(vinyl acetate)) (PVP-b-PVAc) block copolymers of varying molecular weight and hydrophobic block lengths were synthesized via controlled radical polymerization and investigated as carriers for the solubilization of highly hydrophobic riminophenazine compounds. These compounds have r...

journal_title：Biomacromolecules

authors： Bailly N,Thomas M,Klumperman B

更新日期：2012-12-10 00:00:00

abstract：:Collagen is a versatile structural molecule in nature and is used as a building block in many highly organized tissues, such as bone, skin, and cornea. The functionality and performance of these tissues are controlled by their hierarchical organization ranging from the molecular up to macroscopic length scales. In the...

journal_title：Biomacromolecules

authors： Masic A,Bertinetti L,Schuetz R,Galvis L,Timofeeva N,Dunlop JW,Seto J,Hartmann MA,Fratzl P

更新日期：2011-11-14 00:00:00

abstract：:A new series of cationic, thermo-sensitive, and biodegradable poly(L-lactide)-poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PLLA-PEOz-PLLA) triblock copolymers were synthesized by ring-opening polymerization. With increasing molecular weight and crystallinity of hydrophobic PLLA blocks, the critical micellization concent...

journal_title：Biomacromolecules

authors： Wang CH,Hsiue GH

更新日期：2003-11-01 00:00:00