In Situ Synthesis of Magnetic Field-Responsive Hemicellulose Hydrogels for Drug Delivery.

abstract：:A new, convenient pathway is developed to synthesize highly hydrolytically labile poly(ortho ester amide) (POEA) copolymers that overcomes some of the major weaknesses of the traditional methods of synthesizing poly(ortho esters) and their derivatives. A diamine monomer containing a built-in, stabilized ortho ester gr...

journal_title：Biomacromolecules

authors： Tang R,Palumbo RN,Ji W,Wang C

更新日期：2009-04-13 00:00:00

abstract：:For efficient reversal of multidrug resistance (MDR) in chemotherapy for breast cancer, multifunctional self-assembled nanoparticles (MSN) based on a new amphiphilic copolymer consisting of bioreducible poly[bis(2-hydroxylethyl)-disulfide-diacrylate-β-tetraethylenepentamine] and polycaprolactone (PBD-PCL) were constru...

journal_title：Biomacromolecules

authors： Yin Q,Shen J,Zhang Z,Yu H,Chen L,Gu W,Li Y

更新日期：2013-07-08 00:00:00

abstract：:Coiled coils are a common structural motif in many natural proteins that can also be utilized in the design and preparation of drug delivery systems for the noncovalent connection of two macromolecules. In this work, two different pairs of peptides forming coiled coil hetero-oligomers were designed, synthesized, and c...

journal_title：Biomacromolecules

authors： Pechar M,Pola R,Laga R,Braunová A,Filippov SK,Bogomolova A,Bednárová L,Vaněk O,Ulbrich K

更新日期：2014-07-14 00:00:00

abstract：:Silkworm silk has excellent mechanical properties, biocompatibility, and promising applications in the biomedical sector. Silkworms spin silk at the beginning and end of each of their five instar stages, as well as spinning mature silk after the fifth instar. We evaluated the mechanical properties and structure of 10 ...

journal_title：Biomacromolecules

authors： Peng Z,Yang X,Liu C,Dong Z,Wang F,Wang X,Hu W,Zhang X,Zhao P,Xia Q

更新日期：2019-03-11 00:00:00

abstract：:The objective of this study was to explore the use of reverse thermo-responsive (RTG) polymers for generating implants at their site of performance, following minimally invasive surgical procedures. Aiming at combining syringability and enhanced mechanical properties, a new family of injectable RTG-displaying polymers...

journal_title：Biomacromolecules

authors： Cohn D,Sosnik A,Garty S

更新日期：2005-05-01 00:00:00

abstract：:The thermally induced aggregation of bovine β-lactoglobulin in the glass state was studied both as the pure protein and in trehalose mixtures. Calorimetric measurements and size exclusion chromatography were used to characterize the glass state and aggregation, respectively. The initial aggregation rate was characteri...

journal_title：Biomacromolecules

authors： Pérez-Moral N,Adnet C,Noel TR,Parker R

更新日期：2010-11-08 00:00:00

abstract：:Collagen is a versatile structural molecule in nature and is used as a building block in many highly organized tissues, such as bone, skin, and cornea. The functionality and performance of these tissues are controlled by their hierarchical organization ranging from the molecular up to macroscopic length scales. In the...

journal_title：Biomacromolecules

authors： Masic A,Bertinetti L,Schuetz R,Galvis L,Timofeeva N,Dunlop JW,Seto J,Hartmann MA,Fratzl P

更新日期：2011-11-14 00:00:00

abstract：:This study shows the application of the electrospinning technique as a viable method for the encapsulation and stabilization of bifidobacterial strains. Poly(vinyl alcohol) (PVOH) was used as the encapsulating material because it is generally recognized as safe (GRAS), has a high oxygen barrier when dry, and is water ...

journal_title：Biomacromolecules

authors： López-Rubio A,Sanchez E,Sanz Y,Lagaron JM

更新日期：2009-10-12 00:00:00

abstract：:An appropriate modification technique for silk materials is needed to effectively improve their physical properties for specific applications. A telechelic-type polyalanine (T-polyA) was synthesized by papain-catalyzed polymerization as a novel reinforcing agent for silk materials. A silk fibroin obtained from Bombyx ...

journal_title：Biomacromolecules

authors： Tsuchiya K,Masunaga H,Numata K

更新日期：2017-03-13 00:00:00

abstract：:The purpose of this study was to gain mechanistic insights into the effect of different formulation parameters on the degradation and release behavior of protein-loaded nanoparticulate carrier systems based on an aliphatic polyester with pendant hydroxyl groups, poly(lactic-co-glycolic-hydroxymethyl glycolic acid) (pL...

journal_title：Biomacromolecules

authors： Samadi N,van Nostrum CF,Vermonden T,Amidi M,Hennink WE

更新日期：2013-04-08 00:00:00

abstract：:Marine mussels tether to seashore surfaces with byssal threads, proteinaceous fibers that effectively dissipate energy from crashing waves. Protein-metal coordination bonds have been proposed to contribute to the characteristic mechanical and self-healing properties of byssal threads; however, very little is understoo...

journal_title：Biomacromolecules

authors： Schmitt CN,Politi Y,Reinecke A,Harrington MJ

更新日期：2015-09-14 00:00:00

abstract：:Hemicellulose-based hydrogels were prepared by radical polymerization of 2-hydroxyethyl methacrylate or poly(ethylene glycol) dimethacrylate with oligomeric hydrosoluble hemicellulose modified with well-defined amounts of methacrylic functions. The polymerization reaction was carried out in water at 40 degrees C using...

journal_title：Biomacromolecules

authors： Söderqvist Lindblad M,Albertsson AC,Ranucci E,Laus M,Giani E

更新日期：2005-03-01 00:00:00

abstract：:This article reports on the successful preparation and characterization of cellulose nanocrystals (CNCs) surface-modified with polylactide (PLA) and poly(butylene succinate) (PBS) binary mixed homopolymer brushes. Their synthesis was designed as a three-step procedure combining polyester synthesis and surface-modifica...

journal_title：Biomacromolecules

authors： Mincheva R,Jasmani L,Josse T,Paint Y,Raquez JM,Gerbaux P,Eyley S,Thielemans W,Dubois P

更新日期：2016-09-12 00:00:00

abstract：:To evaluate the antidiarrheal effect of ginseng, the active principals of ginseng were studied in vitro model of rotavirus infection, the leading cause of severe diarrhea. Two pectic polysaccharides, named as GP50-dHR (56.0 kDa) and GP50-eHR (77.0 kDa), were purified from hot water extract of ginseng by bioassay-linke...

journal_title：Biomacromolecules

authors： Baek SH,Lee JG,Park SY,Bae ON,Kim DH,Park JH

更新日期：2010-08-09 00:00:00

abstract：:A hyperbranched conjugated polyelectrolyte (HCPE) with a core-shell structure is designed and synthesized via alkyne polycyclotrimerization and click chemistry. The HCPE has an emission maximum at 565 nm with a quantum yield of 12% and a large Stokes shift of 143 nm in water. By virtue of its poly(ethylene glycol) she...

journal_title：Biomacromolecules

authors： Pu KY,Shi J,Cai L,Li K,Liu B

更新日期：2011-08-08 00:00:00

abstract：:Macromolecular dynamics in biological systems, which play a crucial role for biomolecular function and activity at ambient temperature, depend strongly on moisture content. Yet, a generally accepted quantitative model of hydration-dependent phenomena based on local relaxation and diffusive dynamics of both polymer and...

journal_title：Biomacromolecules

authors： Chen P,Terenzi C,Furó I,Berglund LA,Wohlert J

更新日期：2018-07-09 00:00:00

abstract：:pH-dependent release from monoolein (MO) cubic phase was obtained by taking advantage of complex coacervation between hydrophobically modified alginate (HmAL) and hydrophobically modified silk fibroin (HmSF) in the water channels. The degree of coacervation was investigated at pH 3.0 by a light scattering method and t...

journal_title：Biomacromolecules

authors： Kwon TK,Kim JC

更新日期：2011-02-14 00:00:00

abstract：:Effects of poly(ethylene glycol) (PEG) conjugation on peptide interactions with lipid membranes and lipopolysaccharide (LPS) were investigated for KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), an antimicrobial and anti-inflammatory peptide derived from human heparin cofactor II. In particular, effects of PEG length and locali...

journal_title：Biomacromolecules

authors： Singh S,Papareddy P,Mörgelin M,Schmidtchen A,Malmsten M

更新日期：2014-04-14 00:00:00

abstract：:A three-dimensional structure consisting of poly(ε-caprolactone) (PCL) nanofibers covered by periodically spaced PCL crystal lamellae, a self-induced nanohybrid shish-kebab (SINSK) structure, was created using electrospinning followed by a self-induced crystallization. The resulting structure that resembles the nanoto...

journal_title：Biomacromolecules

authors： Wang X,Salick MR,Wang X,Cordie T,Han W,Peng Y,Li Q,Turng LS

更新日期：2013-10-14 00:00:00

abstract：:Reversible stereoselective complexes were spontaneously obtained from mixing acetonitrile solutions of enatiomeric d-poly(lactic acid) (d-PLA), l-poly(lactic acid) (l-PLA), and leuprolide, a l-configured nonapeptide LHRH analogue. The complex spontaneously aggregated and precipitated in high yields (>90%) from acetoni...

journal_title：Biomacromolecules

authors： Slager J,Domb AJ

更新日期：2003-09-01 00:00:00

abstract：:Noncontact mode atomic force microscopy was used to investigate native silk proteins prepared in different ways. Low protein concentrations revealed that single protein molecules exhibit a simple, round shape with apparent diameters of 20-25 nm. Shearing the native protein solutions after extraction from the gland and...

journal_title：Biomacromolecules

authors： Greving I,Cai M,Vollrath F,Schniepp HC

更新日期：2012-03-12 00:00:00

abstract：:The extracellular matrix is an environment rich with structural, mechanical, and molecular signals that can impact cell biology. Traditional approaches in hydrogel biomaterial design often rely on modifying the concentration of cross-linking groups to adjust mechanical properties. However, this strategy provides limit...

journal_title：Biomacromolecules

authors： Pedron S,Pritchard AM,Vincil GA,Andrade B,Zimmerman SC,Harley BA

更新日期：2017-04-10 00:00:00

abstract：:Many biological processes are regulated by reversible binding events, with these interactions between macromolecules representing the core of dynamic chemistry. As such, any attempt to gain a better understanding of such interactions, which would pave the way to the extrapolation of natural designs to create new advan...

journal_title：Biomacromolecules

authors： Fernández-Colino A,Arias FJ,Alonso M,Rodríguez-Cabello JC

更新日期：2015-10-12 00:00:00

abstract：:The nature of the hydration of proteins and the subsequent implications for functionality is a matter of importance in both pharmaceutical and food applications. Most published studies rely on the use of one technique and attempt to characterize the system. Few studies have used combinations of techniques. In this pap...

journal_title：Biomacromolecules

authors： Almutawah A,Barker SA,Belton PS

更新日期：2007-05-01 00:00:00

abstract：:In this work, we have analyzed the structural, topographical, and surface dilatational characteristics of pure beta-lactoglobulin adsorbed films and the effect of the self-assembly of monoglycerides (monopalmitin or monoolein) in beta-lactoglobulin films at the air-water interface. Measurements were performed in a sin...

journal_title：Biomacromolecules

authors： Rodríguez Patino JM,Fernandez MC,Rodríguez Niño MR,Sanchez CC

更新日期：2006-09-01 00:00:00

abstract：:This paper describes the synthesis and characterization of a novel organic polymer coating for the prevention of the growth of Pseudomonas aeruginosa on the solid surface of three-dimensional objects. Substrata were encapsulated with polyterpenol thin films prepared from terpinen-4-ol using radio frequency plasma enha...

journal_title：Biomacromolecules

authors： Bazaka K,Jacob MV,Truong VK,Wang F,Pushpamali WA,Wang JY,Ellis AV,Berndt CC,Crawford RJ,Ivanova EP

更新日期：2010-08-09 00:00:00

abstract：:In biomedicine, PEGylation is one of the most successful strategies to modify the physicochemical and biological properties of peptides, proteins, and other biomacromolecules. Because of the polydisperse nature of regular PEGs and limited PEGylation strategies, it is challenging to quantitatively fine-tune and accurat...

journal_title：Biomacromolecules

authors： Wang X,Li Y,Wu T,Yang Z,Zheng X,Chen S,Zhou X,Jiang ZX

更新日期：2020-02-10 00:00:00

abstract：:In tissue engineering, incorporation of bone morphogenetic protein-2 (BMP-2) into biomaterial scaffolds is an attractive strategy to stimulate bone repair. However, suboptimal release of BMP-2 remains a great concern, which may cause unfavorable bone formation as well as severe inflammation. In this study, genipin-cro...

journal_title：Biomacromolecules

authors： Zhang Q,Tan K,Zhang Y,Ye Z,Tan WS,Lang M

更新日期：2014-01-13 00:00:00

abstract：:Enzymatic adsorption and degradation of three types of aliphatic polyester films and two types of polyolefin films by the extracellular PHB depolymerase from Alcaligenes faecalis T1 have been studied by using a quartz crystal microbalance (QCM) technique. Hydrolysis of poly[(R)-3-hydroxybutyrate] was quantitatively fo...

journal_title：Biomacromolecules

authors： Yamashita K,Aoyagi Y,Abe H,Doi Y

更新日期：2001-04-01 00:00:00

abstract：:The interaction of iron with water-soluble polymer chitosan and monomer d-glucosamine is investigated by Mössbauer spectroscopy. The 4.2 K Mössbauer spectrum of Fe-water-soluble chitosan complex indicates the presence of a magnetic pattern and a quadrupole doublet, and analysis of the spectral data leads to the conclu...

journal_title：Biomacromolecules

authors： Bhatia SC,Ravi N

更新日期：2003-05-01 00:00:00