Binary Mixed Homopolymer Brushes Tethered to Cellulose Nanocrystals: A Step Towards Compatibilized Polyester Blends.

abstract：:In this study, generation 5 (G5) polyamidoamine (PAMAM) dendrimers with two different surface groups, G4.5-COOH and G5-OH, were investigated for their protective effects on pancreas injury in a caerulein-induced acute pancreatitis (AP) mouse model. Both dendrimers significantly decreased pathological changes in the pa...

journal_title：Biomacromolecules

authors： Tang Y,Han Y,Liu L,Shen W,Zhang H,Wang Y,Cui X,Wang Y,Liu G,Qi R

更新日期：2015-01-12 00:00:00

abstract：:The proteinaceous material present in beta-lactoglobulin fibrils formed after heating (20 h at 85 degrees C) at pH 2 was identified during this study. Fibrils were separated from the nonaggregated material, and the fibrils were dissociated using 8 M guanidine chloride and 0.1 M 1,4-dithiothreitol (pH 8). Characterizat...

journal_title：Biomacromolecules

authors： Akkermans C,Venema P,van der Goot AJ,Gruppen H,Bakx EJ,Boom RM,van der Linden E

更新日期：2008-05-01 00:00:00

abstract：:Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligome...

journal_title：Biomacromolecules

authors： Nallani M,de Hoog HP,Cornelissen JJ,Palmans AR,van Hest JC,Nolte RJ

更新日期：2007-12-01 00:00:00

abstract：:Degradation of fibrillar collagen is critical for tissue maintenance. Yet, understanding collagen catabolism has been challenging partly due to a lack of atomistic picture for its load-dependent conformational dynamics, as both mechanical load and local unfolding of collagen affect its cleavage by matrix metalloprotei...

journal_title：Biomacromolecules

authors： Teng X,Hwang W

更新日期：2014-08-11 00:00:00

abstract：:Fluorescence and circular dichroism spectroscopy were used to monitor the conformational transition of regenerated Bombyx mori silk fibroin (RSF) in aqueous solutions under different conditions. According to the analysis of fluorescence spectra using anilinonaphthalene-8-sulfonic acid magnesium salt (ANS) as an extern...

journal_title：Biomacromolecules

authors： Yang Y,Shao Z,Chen X,Zhou P

更新日期：2004-05-01 00:00:00

abstract：:This work demonstrates a versatile and environmentally friendly route for the development of new orthogonal monomers that can be used for postfunctionalizable polymer networks. A monomer containing both vinyl ether (VE) and cyclic disulfide moieties was synthesized via enzyme catalysis under benign reaction conditions...

journal_title：Biomacromolecules

authors： Brännström S,Johansson M,Malmström E

更新日期：2019-03-11 00:00:00

abstract：:Sulfated glycosaminoglycans (GAGs) can direct cellular processes by interacting with proteins of the extracellular matrix (ECM). In this study we characterize the interaction profiles of chemically sulfated hyaluronan (HA) and chondroitin sulfate (CS) derivatives with bone morphogenetic protein-2 (BMP-2) and investiga...

journal_title：Biomacromolecules

authors： Hintze V,Samsonov SA,Anselmi M,Moeller S,Becher J,Schnabelrauch M,Scharnweber D,Pisabarro MT

更新日期：2014-08-11 00:00:00

abstract：:Glycerol derivatives of cutin and suberin monomers were synthesized by acid catalysis. Their dispersion in an aqueous solution was examined by phase contrast microscopy, neutron scattering, and solid state NMR. It is shown that the phase behavior strongly depends on the nature of the derivatives forming either lumps o...

journal_title：Biomacromolecules

authors： Douliez JP,Barrault J,Jerome F,Heredia A,Navailles L,Nallet F

更新日期：2005-01-01 00:00:00

abstract：:Although doxorubicin (Dox) has been widely used in the treatment of different types of cancer, its insufficient cellular uptake and intracellular release is still a limitation. Herein, we report an easy process for the preparation of redox-sensitive nanogels that were shown to be highly efficient in the intracellular ...

journal_title：Biomacromolecules

authors： Maciel D,Figueira P,Xiao S,Hu D,Shi X,Rodrigues J,Tomás H,Li Y

更新日期：2013-09-09 00:00:00

abstract：:Effects of poly(ethylene glycol) (PEG) conjugation on peptide interactions with lipid membranes and lipopolysaccharide (LPS) were investigated for KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), an antimicrobial and anti-inflammatory peptide derived from human heparin cofactor II. In particular, effects of PEG length and locali...

journal_title：Biomacromolecules

authors： Singh S,Papareddy P,Mörgelin M,Schmidtchen A,Malmsten M

更新日期：2014-04-14 00:00:00

abstract：:Electrospinning for the formation of nanoscale diameter fibers has been explored for high-performance filters and biomaterial scaffolds for vascular grafts or wound dressings. Fibers with nanoscale diameters provide benefits due to high surface area. In the present study we explore electrospinning for protein-based bi...

journal_title：Biomacromolecules

authors： Jin HJ,Fridrikh SV,Rutledge GC,Kaplan DL

更新日期：2002-11-01 00:00:00

abstract：:In the present work, a novel synthetic methodology for the preparation of scaffold of biopolymeric nature is described. In particular, a porous gelatin scaffold was prepared by foam templating. The gas phase, nitrogen, was generated by means of the reaction between sulfamic acid and sodium nitrite in situ a concentrat...

journal_title：Biomacromolecules

authors： Barbetta A,Gumiero A,Pecci R,Bedini R,Dentini M

更新日期：2009-12-14 00:00:00

abstract：:Under the right conditions, some biological systems can maintain high viability after being frozen and thawed, but many others (e.g., organs and many mammalian cells) cannot. To increase the rates of post-thaw viability and widen the library of living cells and tissues that can be stored frozen, an improved understand...

journal_title：Biomacromolecules

authors： Burkey AA,Hillsley A,Harris DT,Baltzegar JR,Zhang DY,Sprague WW,Rosales AM,Lynd NA

更新日期：2020-08-10 00:00:00

abstract：:As an aim toward developing biologically mimetic and functional nanofiber-based tissue engineering scaffolds, we demonstrated the encapsulation of a model protein, fluorescein isothiocyanate-conjugated bovine serum albumin (fitcBSA), along with a water-soluble polymer, poly(ethylene glycol) (PEG), within the biodegrad...

journal_title：Biomacromolecules

authors： Zhang YZ,Wang X,Feng Y,Li J,Lim CT,Ramakrishna S

更新日期：2006-04-01 00:00:00

abstract：:Acrylic acid (AAc) has been utilized to introduce reactive carboxyl groups to a temperature-responsive polymer, poly(N-isopropylacrylamide) (PIPAAm). However, AAc introduction shifts the copolymer phase transition temperatures higher and dampens the steep homopolymer phase transition with increasing AAc content. We pr...

journal_title：Biomacromolecules

authors： Ebara M,Yamato M,Hirose M,Aoyagi T,Kikuchi A,Sakai K,Okano T

更新日期：2003-03-01 00:00:00

abstract：:Dynamic shear oscillation measurements at small strain were used to characterize the viscoelastic properties and related differences in the molecular structure of hydrogels based on gelatin methacrylamide. Gelatin was derivatized with methacrylamide side groups and was subsequently cross-linked by radical polymerizati...

journal_title：Biomacromolecules

authors： Van Den Bulcke AI,Bogdanov B,De Rooze N,Schacht EH,Cornelissen M,Berghmans H

更新日期：2000-04-01 00:00:00

abstract：:Relative to normal cells, tumor cells lack adequate capability of reactive oxygen scavenging. Thus, tumor cells can be selectively killed by increasing the concentration of reactive oxygen species in tumor tissue. In this report, we construct an integrated multifunctional polymeric nanoparticle which can selectively i...

journal_title：Biomacromolecules

authors： Wang Y,Yin W,Ke W,Chen W,He C,Ge Z

更新日期：2018-06-11 00:00:00

abstract：:The growing importance of biodegradable conducting polymers (CPs) have fueled the rapid development of this unique class of polymeric materials in recent years. Possessing both the electrical conductivity approaching those of metallic conductors and the biodegradability of biocompatible polymers, biodegradable CPs are...

journal_title：Biomacromolecules

authors： Kenry,Liu B

更新日期：2018-06-11 00:00:00

abstract：:A drying environment is always a proposition faced by dynamic living organisms using water, which are driven by biopolymer-based micro- and macrostructures. Here, we introduce a drying process for aqueous liquid crystalline (LC) solutions composed of biopolymer with extremely high molecular weight components such as p...

journal_title：Biomacromolecules

authors： Okeyoshi K,Okajima MK,Kaneko T

更新日期：2016-06-13 00:00:00

abstract：:Tumorigenic cell behaviors can be suppressed or enhanced by their physicochemical environment. As a first step toward developing materials that allow tumorigenic behaviors to be observed and manipulated, we cultured related MCF10 breast cell lines on fibers composed of the Drosophila protein Ultrabithorax (Ubx). These...

journal_title：Biomacromolecules

authors： Hsiao HC,Santos A,Howell DW,Patterson JL,Fuchs-Young RS,Bondos SE

更新日期：2016-11-14 00:00:00

abstract：:The ability to direct neurite growth into a close proximity of stimulating elements of a neural prosthesis, such as a retinal or cochlear implant (CI), may enhance device performance and overcome current spatial signal resolution barriers. In this work, spiral ganglion neurons (SGNs), which are the target neurons to b...

journal_title：Biomacromolecules

authors： Tuft BW,Zhang L,Xu L,Hangartner A,Leigh B,Hansen MR,Guymon CA

更新日期：2014-10-13 00:00:00

abstract：:Enzymatic ring-opening copolymerization of 5-benzyloxy-trimethylene carbonate (BTMC) and 1,4-dioxan-2-one (DON) was investigated for the first time. Immobilized porcine pancreas lipase (IPPL) on silica particles was selected to perform the copolymerization. A series of novel biodegradable copolymers with different com...

journal_title：Biomacromolecules

authors： He F,Jia HL,Liu G,Wang YP,Feng J,Zhuo RX

更新日期：2006-08-01 00:00:00

abstract：:The positive interaction of materials with tissues is an important step in regenerative medicine strategies. Hydrogels that are obtained from polysaccharides and proteins are expected to mimic the natural cartilage environment and thus provide an optimum milleu for tissue growth and regeneration. In this work, novel h...

journal_title：Biomacromolecules

authors： Silva SS,Motta A,Rodrigues MT,Pinheiro AF,Gomes ME,Mano JF,Reis RL,Migliaresi C

更新日期：2008-10-01 00:00:00

abstract：:We investigate lysozyme-lysozyme and lysozyme-salt interactions in electrolyte solutions using a molecular-thermodynamic model. An equation of state based on the statistical mechanical perturbation theory is applied to describe the interactions. The perturbation term includes a new square-well potential of mean force,...

journal_title：Biomacromolecules

authors： Chang BH,Bae YC

更新日期：2003-11-01 00:00:00

abstract：:This paper presents the formation of a novel biomimetic interface consisting of an electrolessly deposited gold film overlaid with a tethered bilayer lipid membrane (tBLM). Self-assembly of colloidal gold particles was used to create an electrolessly deposited gold film on a glass slide. The properties of the film wer...

journal_title：Biomacromolecules

authors： Kohli N,Hassler BL,Parthasarathy L,Richardson RJ,Ofoli RY,Worden RM,Lee I

更新日期：2006-12-01 00:00:00

abstract：:Coniferyl alcohol was polymerized in pectin solution in order to mimic the lignification that is the final step of biosynthesis of plant cell wall. Dehydrogenated polymers (DHP = coniferyl alcohol polymers = synthetic lignin) interact with pectin to form hydrophobic clusters as monitored by pyrene fluorescence spectro...

journal_title：Biomacromolecules

authors： Lairez D,Cathala B,Monties B,Bedos-Belval F,Duran H,Gorrichon L

更新日期：2005-03-01 00:00:00

abstract：:Bioprinting has become an important tool for fabricating regenerative implants and in vitro cell culture platforms. However, until today, extrusion-based bioprinting processes are limited to resolutions of hundreds of micrometers, which hamper the reproduction of intrinsic functions and morphologies of living tissues....

journal_title：Biomacromolecules

authors： Castilho M,Levato R,Bernal PN,de Ruijter M,Sheng CY,van Duijn J,Piluso S,Ito K,Malda J

更新日期：2021-01-07 00:00:00

abstract：:A porous scaffold as a cell-compatible material was designed and prepared using a phospholipid copolymer composed of 2-methacryloyloxyethyl phosphorylcholine (MPC), n-butyl methacrylate, and enantiomeric macromonomers, the poly(L-lactic acid) (PLLA) macromonomer, and poly(D-lactic acid) (PDLA) macromonomer. On the bas...

journal_title：Biomacromolecules

authors： Watanabe J,Eriguchi T,Ishihara K

更新日期：2002-09-01 00:00:00

abstract：:Copolymers of (R)-3-hydroxybutyric acid (HB) and epsilon-caprolactone (CL) with a composition ranging from 28 to 81 mol % of HB were synthesized by transesterification of the corresponding homopolymers in solution in the presence of 4-toluenesulfonic acid. The copolyesters were characterized with regard to their molec...

journal_title：Biomacromolecules

authors： Impallomeni G,Giuffrida M,Barbuzzi T,Musumarra G,Ballistreri A

更新日期：2002-07-01 00:00:00

abstract：:One of the major drawbacks found in most bone tissue engineering approaches developed so far consists in the lack of strategies to promote vascularisation. Some studies have addressed different issues that may enhance vascularisation in tissue engineered constructs, most of them involving the use of growth factors (GF...

journal_title：Biomacromolecules

authors： Santo VE,Frias AM,Carida M,Cancedda R,Gomes ME,Mano JF,Reis RL

更新日期：2009-06-08 00:00:00