Abstract:
:Comparison of population differentiation in neutral marker genes and in genes coding quantitative traits by means of F(ST) and Q(ST) indexes has become commonplace practice. While the properties and estimation of F(ST) have been the subject of much interest, little is known about the precision and possible bias in Q(ST) estimates. Using both simulated and real data, we investigated the precision and bias in Q(ST) estimates and various methods of estimating the precision. We found that precision of Q(ST) estimates for typical data sets (i.e., with <20 populations) was poor. Of the methods for estimating the precision, a simulation method, a parametric bootstrap, and the Bayesian approach returned the most precise estimates of the confidence intervals.
journal_name
Geneticsjournal_title
Geneticsauthors
O'Hara RB,Merilä Jdoi
10.1534/genetics.105.044545keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1331-9issue
3eissn
0016-6731issn
1943-2631pii
genetics.105.044545journal_volume
171pub_type
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