Analysis of the inheritance, selection and evolution of growth trajectories.

abstract：:The African fish Nothobranchius furzeri is the shortest-lived vertebrate species that can reproduce in captivity, with a median life span of 9-11 weeks for the shortest-lived strain. Natural populations of N. furzeri display differences in life span, aging biomarkers, behavior, and color, which make N. furzeri a uniqu...

journal_title：Genetics

authors： Valenzano DR,Kirschner J,Kamber RA,Zhang E,Weber D,Cellerino A,Englert C,Platzer M,Reichwald K,Brunet A

更新日期：2009-12-01 00:00:00

abstract：:A consensus map for loblolly pine (Pinus taeda L.) was constructed from the integration of linkage data from two unrelated three-generation outbred pedigrees. The progeny segregation data from restriction fragment length polymorphism, random amplified polymorphic DNA, and isozyme genetic markers from each pedigree wer...

journal_title：Genetics

authors： Sewell MM,Sherman BK,Neale DB

更新日期：1999-01-01 00:00:00

abstract：:Vegetative incompatibility in fungi has long been known to reduce the transmission of viruses between individuals, but the barrier to transmission is incomplete. In replicated laboratory assays, we showed conclusively that the transmission of viruses between individuals of the chestnut blight fungus Cryphonectria para...

journal_title：Genetics

authors： Cortesi P,McCulloch CE,Song H,Lin H,Milgroom MG

更新日期：2001-09-01 00:00:00

abstract：:The heterochromatin of the third chromosome is the largest uncharacterized region of the Drosophila melanogaster genome, and the last major block of D. melanogaster heterochromatin to be thoroughly analyzed. In the present study, this region was genetically dissected by generating and analyzing a series of attached, d...

journal_title：Genetics

authors： Marchant GE,Holm DG

更新日期：1988-10-01 00:00:00

abstract：:I have studied nucleotide polymorphism and linkage disequilibrium using multilocus data from 77 fragments, with an average length of fragments of 550 bp, in the deciduous tree Populus tremula (Salicaceae). The frequency spectrum across loci showed a modest excess of mutations segregating at low frequency and a marked ...

journal_title：Genetics

authors： Ingvarsson PK

更新日期：2008-09-01 00:00:00

abstract：:Reproducing kernel Hilbert spaces regression procedures for prediction of total genetic value for quantitative traits, which make use of phenotypic and genomic data simultaneously, are discussed from a theoretical perspective. It is argued that a nonparametric treatment may be needed for capturing the multiple and com...

journal_title：Genetics

authors： Gianola D,van Kaam JB

更新日期：2008-04-01 00:00:00

abstract：:Many genes that affect axon pathfinding and cell migration have been identified. Mechanisms by which these genes and the molecules they encode interact with one another in pathways and networks to control developmental events are unclear. Rac GTPases, the cytoskeletal signaling molecule Enabled, and NIK kinase have al...

journal_title：Genetics

authors： Shakir MA,Gill JS,Lundquist EA

更新日期：2006-02-01 00:00:00

abstract：:LARK is an essential Drosophila RNA-binding protein of the RNA recognition motif (RRM) class that functions during embryonic development and for the circadian regulation of adult eclosion. LARK protein contains three consensus RNA-binding domains: two RRM domains and a retroviral-type zinc finger (RTZF). To show that ...

journal_title：Genetics

authors： McNeil GP,Schroeder AJ,Roberts MA,Jackson FR

更新日期：2001-09-01 00:00:00

abstract：:Isogenic lines, in which chromosomes sampled from natural populations of C. melanogaster are substituted into a common genetic background, were used to detect and partially characterize autosomal factors that affect the activities of the two pentose phosphate pathway enzymes, glucose 6-phosphate dehydrogenase (G6PD) a...

journal_title：Genetics

authors： Laurie-Ahlberg CC,Williamson JH,Cochrane BJ,Wilton AN,Chasalow FI

更新日期：1981-09-01 00:00:00

abstract：:Selective sweeps are typically associated with a local reduction of genetic diversity around the adaptive site. However, selective sweeps can also quickly carry neutral mutations to observable population frequencies if they arise early in a sweep and hitchhike with the adaptive allele. We show that the interplay betwe...

journal_title：Genetics

authors： Messer PW,Neher RA

更新日期：2012-06-01 00:00:00

abstract：:The prune gene of Drosophila melanogaster is predicted to encode a phosphodiesterase. Null alleles of prune are viable but cause an eye-color phenotype. The abnormal wing discs gene encodes a nucleoside diphosphate kinase. Killer of prune is a missense mutation in the abnormal wing discs gene. Although it has no pheno...

journal_title：Genetics

authors： Provost E,Hersperger G,Timmons L,Ho WQ,Hersperger E,Alcazar R,Shearn A

更新日期：2006-01-01 00:00:00

abstract：:Quantitative trait loci (QTL) affecting milk production and health of dairy cattle were mapped in a very large Holstein granddaughter design. The analysis included 1794 sons of 14 sires and 206 genetic markers distributed across all 29 autosomes and flanking an estimated 2497 autosomal cM using Kosambi's mapping funct...

journal_title：Genetics

authors： Zhang Q,Boichard D,Hoeschele I,Ernst C,Eggen A,Murkve B,Pfister-Genskow M,Witte LA,Grignola FE,Uimari P,Thaller G,Bishop MD

更新日期：1998-08-01 00:00:00

abstract：:Reproductive isolation that initiates speciation is likely caused by incompatibility among multiple loci in organisms belonging to genetically diverging populations. Laboratory C57BL/6J mice, which predominantly originated from Mus musculus domesticus, and a MSM/Ms strain derived from Japanese wild mice (M. m. molossi...

journal_title：Genetics

authors： Oka A,Aoto T,Totsuka Y,Takahashi R,Ueda M,Mita A,Sakurai-Yamatani N,Yamamoto H,Kuriki S,Takagi N,Moriwaki K,Shiroishi T

更新日期：2007-01-01 00:00:00

abstract：:Heterologous yeast artificial chromosomes (YACs) do not recombine with each other and missegregate in 25% of meiosis I events. Recombination hot spots in the yeast Saccharomyces cerevisiae have previously been shown to be associated with sites of meiosis-induced double-strand breaks (DSBs). A 6-kb fragment containing ...

journal_title：Genetics

authors： Sears DD,Hieter P,Simchen G

更新日期：1994-12-01 00:00:00

abstract：:An approximately 135-bp sequence called the A1/A2 repeat was isolated from the transcribed region of the 26-18S rDNA intergenic spacer (IGS) of Nicotiana tomentosiformis. Fluorescence in situ hybridization (FISH) and Southern blot analysis revealed its occurrence as an independent satellite (termed an A1/A2 satellite)...

journal_title：Genetics

authors： Lim KY,Skalicka K,Koukalova B,Volkov RA,Matyasek R,Hemleben V,Leitch AR,Kovarik A

更新日期：2004-04-01 00:00:00

abstract：:In a genetic screen for mutants showing modified splicing of an alternatively spliced GFP reporter gene in Arabidopsis thaliana, we identified mutations in genes encoding the putative U1 small nuclear ribonucleoprotein (snRNP) factors RBM25 and PRP39a. The latter has not yet been studied for its role in pre-messenger ...

journal_title：Genetics

authors： Kanno T,Lin WD,Fu JL,Chang CL,Matzke AJM,Matzke M

更新日期：2017-12-01 00:00:00

abstract：:Zymograms were analyzed of a number of Triticum aestivum derivatives which incorporated a segment of the Aegilops umbellulata chromosome bearing resistance to leaf rust. Evidence has been presented which suggests that genes involved in the production of two peroxidases and a single peptidase are located on the short a...

journal_title：Genetics

authors： Macdonald T,Smith HH

更新日期：1972-09-01 00:00:00

abstract：:A large offspring-number diploid biparental multilocus population model of Moran type is our object of study. At each time step, a pair of diploid individuals drawn uniformly at random contributes offspring to the population. The number of offspring can be large relative to the total population size. Similar "heavily ...

journal_title：Genetics

authors： Birkner M,Blath J,Eldon B

更新日期：2013-01-01 00:00:00

abstract：:We show how to incorporate fluctuations of the recombination rate along the chromosome into standard gene-genealogical models for the decorrelation of gene histories. This enables us to determine how small-scale fluctuations (Poissonian hot-spot model) and large-scale variations (Kong et al. 2002) of the recombination...

journal_title：Genetics

authors： Eriksson A,Mehlig B

更新日期：2005-02-01 00:00:00

abstract：:Position effect variegation results from chromosome rearrangements which translocate euchromatic genes close to the heterochromatin. The euchromatin-heterochromatin association is responsible for the inactivation of these genes in some cell clones. In Drosophila melanogaster the Y chromosome, which is entirely heteroc...

journal_title：Genetics

authors： Dimitri P,Pisano C

更新日期：1989-08-01 00:00:00

abstract：:To understand gene function, the cre/loxP conditional system is the most powerful available for temporal and spatial control of expression in mouse. However, the research community requires more cre recombinase expressing transgenic mouse strains (cre-drivers) that restrict expression to specific cell types. To addres...

journal_title：Genetics

authors： Korecki AJ,Hickmott JW,Lam SL,Dreolini L,Mathelier A,Baker O,Kuehne C,Bonaguro RJ,Smith J,Tan CV,Zhou M,Goldowitz D,Deussing JM,Stewart AF,Wasserman WW,Holt RA,Simpson EM

更新日期：2019-04-01 00:00:00

abstract：:The distribution within anthers of maize plants of microsporocytes of differing crossover class was studied by application of the serial-sectioning technique to plants heterozygous for a paracentric inversion. In such material, cells with four-strand double crossovers within the inversion are distinguishable from cell...

journal_title：Genetics

authors： Maguire MP

更新日期：1980-05-01 00:00:00

abstract：:In the Brassicaceae, self-vs. nonself-recognition in self-incompatibility is controlled by sporophytic S-alleles. Haplotypes specifying both SRK (S-receptor kinase) and SLG (S-locus glycoprotein) are considered to play an important role in the recognition reactions. We compared the nucleotide sequences of SRK9(Bc) and...

journal_title：Genetics

authors： Hinata K,Watanabe M,Yamakawa S,Satta Y,Isogai A

更新日期：1995-07-01 00:00:00

abstract：:Mutations in the genealogy of the sequences in a random sample from a population can be classified as external and internal. External mutations are mutations that occurred in the external branches and internal mutations are mutations that occurred in the internal branches of the genealogy. Under the assumption of sele...

journal_title：Genetics

authors： Fu YX,Li WH

更新日期：1993-03-01 00:00:00

abstract：:Malaria control projects based on the introduction and spread of transgenes into mosquito populations depend on the extent of isolation between those populations. On the basis of the distribution of paracentric inversions, Anopheles gambiae has been subdivided into five subspecific chromosomal forms. Estimating gene f...

journal_title：Genetics

authors： Tripet F,Dolo G,Lanzaro GC

更新日期：2005-01-01 00:00:00

abstract：:Haploid Saccharomyces can change mating type through HO-endonuclease cleavage of an expressor locus, MAT, followed by gene conversion using one of two repository loci, HML or HMR, as donor. The mating type of a cell dictates which repository locus is used as donor, with a cells using HML and alpha cells using HMR. Thi...

journal_title：Genetics

authors： Houston P,Simon PJ,Broach JR

更新日期：2004-03-01 00:00:00

abstract：:Genetic divergence in the form of the mandible is examined in ten inbred strains of mice. Several univariate and multivariate genetic distance estimates are given for the morphological data and these estimates are compared to measures of genealogical and molecular divergence. Highly significant divergence occurs among...

journal_title：Genetics

authors： Atchley WR,Newman S,Cowley DE

更新日期：1988-09-01 00:00:00

abstract：:We have studied how a set of male-specific sensory neurons in Caenorhabditis elegans establish axonal connections during postembryonic development. In the adult male, 9 bilateral pairs of ray sensory neurons innervate an acellular fan that serves as a presumptive tactile and olfactory organ during copulation. We visua...

journal_title：Genetics

authors： Jia L,Emmons SW

更新日期：2006-07-01 00:00:00

abstract：:In most eukaryotes, crossovers are not independently distributed along the length of a chromosome. Instead, they appear to avoid close proximity to one another--a phenomenon known as crossover interference. Previously, for three of the five Arabidopsis chromosomes, we measured the strength of interference and suggeste...

journal_title：Genetics

authors： Lam SY,Horn SR,Radford SJ,Housworth EA,Stahl FW,Copenhaver GP

更新日期：2005-06-01 00:00:00

abstract：:The L1 family of single-pass transmembrane cell adhesion molecules (L1CAMs) is conserved from Caenorhabditis elegans and Drosophila to vertebrates and is required for axon guidance, neurite outgrowth, and maintenance of neuronal positions. The extracellular region of L1CAMs mediates cell adhesion via interactions with...

journal_title：Genetics

authors： Zhou S,Opperman K,Wang X,Chen L

更新日期：2008-11-01 00:00:00