Abstract:
:DNA sequence analysis and genetic mapping of loci from mating-type-specific chromosomes of the smut fungus Microbotryum violaceum demonstrated that the nonrecombining mating-type-specific region in this species comprises approximately 25% ( approximately 1 Mb) of the chromosome length. Divergence between homologous mating-type-linked genes in this region varies between 0 and 8.6%, resembling the evolutionary strata of vertebrate and plant sex chromosomes.
journal_name
Geneticsjournal_title
Geneticsauthors
Votintseva AA,Filatov DAdoi
10.1534/genetics.109.103192subject
Has Abstractpub_date
2009-08-01 00:00:00pages
1391-6issue
4eissn
0016-6731issn
1943-2631pii
genetics.109.103192journal_volume
182pub_type
杂志文章相关文献
GENETICS文献大全abstract::Chromatin insulators separate active from repressed chromatin domains. In yeast the RNA pol III transcription machinery bound to tRNA genes function with histone acetylases and chromatin remodelers to restrict the spread of heterochromatin. Our results collectively demonstrate that binding of TFIIIC is necessary for i...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.109.106203
更新日期:2009-09-01 00:00:00
abstract::Research on the genetics of natural populations was revolutionized in the 1990s by methods for genotyping noninvasively collected samples. However, these methods have remained largely unchanged for the past 20 years and lag far behind the genomics era. To close this gap, here we report an optimized laboratory protocol...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.116.187492
更新日期:2016-06-01 00:00:00
abstract::Zymograms were analyzed of a number of Triticum aestivum derivatives which incorporated a segment of the Aegilops umbellulata chromosome bearing resistance to leaf rust. Evidence has been presented which suggests that genes involved in the production of two peroxidases and a single peptidase are located on the short a...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1972-09-01 00:00:00
abstract::A spontaneously arising nuclear mutation, ss-1, has been identified in Chlamydomonas reinhardtii that decreases both streptomycin and spectinomycin resistance levels about 10-fold after its introduction into all wild-type, streptomycin-resistant and spectinomycin-resistant strains examined. The mutations for resistanc...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::Chromosomal double-strand breaks (DSBs) that have only one end with homology to a donor duplex undergo repair by strand invasion followed by replication to the chromosome terminus (break-induced replication, BIR). Using a transformation-based assay system, it was previously shown that BIR could occur by several rounds...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.114.162297
更新日期:2014-04-01 00:00:00
abstract::Conversion between duplicated genes limits their independent evolution. Models in which conversion frequencies decrease as genes diverge are examined to determine conditions under which genes can "escape" further conversion and hence escape from a gene family. A review of results from various recombination systems sug...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract::To further understand how the nematode Caenorhabditis elegans defends itself against pathogen attack, we analyzed enhanced pathogen resistance (epr) mutants obtained from a forward genetic screen. We also examined several well-characterized sterile mutants that exhibit an Epr phenotype. We found that sterility and pat...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.107.083923
更新日期:2008-02-01 00:00:00
abstract::Sequence divergence among the mitochondrial (mt) DNA of nine Lycopersicon and two closely related Solanum species was estimated using the shared fragment method. A portion of each mt genome was highlighted by probing total DNA with a series of plasmid clones containing mt-specific DNA fragments from Lycopersicon penne...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1986-03-01 00:00:00
abstract::Allorecognition is ubiquitous, or nearly so, amongst colonial invertebrates. Despite the prominent role that such phenomena have played both in evolutionary theory and in on the origin of the vertebrate immune system, unambiguous data on the transmission genetics of fusibility (i.e., the ability of two individuals to ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::Actin is a major component of the cytoskeleton and one of the most abundant proteins found in eukaryotic cells. Comparative sequence analysis shows that this essential gene has been highly conserved throughout eukaryotic evolution making it useful for phylogenetic analysis. Complete cDNA clones for the actin-encoding ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::It is well known that an allele causing increased recombination is expected to proliferate as a result of genetic drift in a finite population undergoing selection, without requiring other mechanisms. This is supported by recent simulations apparently demonstrating that, in small populations, drift is more important t...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::Evidence from many organisms indicates that the conserved RecQ helicases function in the maintenance of genomic stability. Mutation of SGS1 and WRN, which encode RecQ homologues in budding yeast and humans, respectively, results in phenotypes characteristic of premature aging. Mutation of SRS2, another DNA helicase, c...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::Microtubules are dynamic structures that must elongate, disassemble, and be cleaved into smaller pieces for proper neuronal development and function. The AAA ATPase Spastin severs microtubules along their lengths and is thought to regulate the balance between long, stable filaments and shorter fragments that seed exte...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.111.130831
更新日期:2011-09-01 00:00:00
abstract::Because some metabolic intermediates are involved in more than one pathway, crosstalk between pathways is crucial to maintaining homeostasis. AMP and histidine biosynthesis pathways are coregulated at the transcriptional level in response to adenine availability. 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole (AICAR...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.104.039396
更新日期:2005-05-01 00:00:00
abstract::Hybrid sterility is a common form of reproductive isolation between nascent species. Although hybrid sterility is routinely documented and genetically dissected in speciation studies, its developmental basis is rarely examined, especially in generations beyond the F1 generation. To identify phenotypic and genetic dete...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.118.301658
更新日期:2018-12-01 00:00:00
abstract::Orthologous positions of 55 genes associated with height in four human populations were located on the bovine genome. Single nucleotide polymorphisms close to eight of these genes were significantly associated with stature in cattle (Bos taurus and Bos indicus). This suggests that these genes may contribute to control...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.110.123943
更新日期:2011-03-01 00:00:00
abstract::The wild-type Salmonella typhimurium strain LT2 contains six copies of the insertion sequence element IS200 which is unique to Salmonella. We have determined the chromosomal locations of all six copies of IS200 in strain LT2. This was done by mapping the positions of Tn10 elements inserted near each copy of IS200. Suc...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::Rates of molecular evolution at some loci are more irregular than described by simple Poisson processes. Three situations under which molecular evolution would not follow simple Poisson processes are reevaluated from the viewpoint of the neutrality hypothesis: concomitant or multiple substitutions in a gene, fluctuati...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::R1 and R2 elements are non-LTR retrotransposons that insert specifically into the 28S rRNA genes of arthropods. The process of concerted evolution of the rDNA locus should give rise to rapid turnover of these mobile elements compared to elements that insert at sites throughout a genome. To estimate the rate of R1 and ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::Paramecium has long been a model eukaryote. The sequence of the Paramecium tetraurelia genome reveals a history of three successive whole-genome duplications (WGDs), and the sequences of P. biaurelia and P. sexaurelia suggest that these WGDs are shared by all members of the aurelia species complex. Here, we present th...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.114.163287
更新日期:2014-08-01 00:00:00
abstract::Epistasis contributes significantly to intrapopulation variation in floral morphology, development time, and male fitness components of Mimulus guttatus. This is demonstrated with a replicated line-cross experiment involving slightly over 7000 plants. The line-cross methodology is based on estimates for means. It thus...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.105.041525
更新日期:2005-12-01 00:00:00
abstract::Polyploidy has occurred throughout the evolutionary history of all eukaryotes and is extremely common in plants. Reunification of the evolutionarily divergent genomes in allopolyploids creates regulatory incompatibilities that must be reconciled. Here we report genomewide gene expression analysis of Arabidopsis synthe...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.105.047894
更新日期:2006-01-01 00:00:00
abstract::Life-history traits or "fitness components"-such as age and size at maturity, fecundity and fertility, age-specific rates of survival, and life span-are the major phenotypic determinants of Darwinian fitness. Analyzing the evolution and genetics of these phenotypic targets of selection is central to our understanding ...
journal_title:Genetics
pub_type: 杂志文章,评审
doi:10.1534/genetics.119.300160
更新日期:2020-01-01 00:00:00
abstract::A method for estimating the average level of gene flow among populations is introduced. The method provides an estimate of Nm, where N is the size of each local population in an island model and m is the migration rate. This method depends on knowing the phylogeny of the nonrecombining segments of DNA that are sampled...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::A correlation between diversity levels and rates of recombination is predicted both by models of positive selection, such as hitchhiking associated with the rapid fixation of advantageous mutations, and by models of purifying selection against strongly deleterious mutations (commonly referred to as "background selecti...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::The three-dimensional (3D) organization of chromosomes can influence transcription. However, the frequency and magnitude of these effects remain debated. To determine how changes in chromosome positioning affect transcription across thousands of genes with minimal perturbation, we characterized nuclear organization an...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.119.302978
更新日期:2020-03-01 00:00:00
abstract::We present methods for estimating the parameters of inheritance and selection that appear in a quantitative genetic model for the evolution growth trajectories and other "infinite-dimensional" traits that we recently introduced. Two methods for estimating the additive genetic covariance function are developed, a "full...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::The Dissociation (Ds) mutant, Bz-wm, of the maize bronze-1 (bz) locus conditions a leaky phenotype. Plants carrying this mutant allele synthesize a low amount of an altered Bz gene product, which leads to reduced anthocyanin pigmentation in the seed. The molecular analysis reported here shows that the Bz-wm mutant has...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::X chromosome inactivation (XCI) is an epigenetic process that almost completely inactivates one of two X chromosomes in somatic cells of mammalian females. A few genes are known to escape XCI and the mechanism for this escape remains unclear. Here, using mouse trophoblast stem (TS) cells, we address whether particular...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.114.162800
更新日期:2014-06-01 00:00:00
abstract::Key steps of essential metabolic pathways are housed in plant peroxisomes. We conducted a microscopy-based screen for anomalous distribution of peroxisomally targeted fluorescence in Arabidopsis thaliana This screen uncovered 34 novel alleles in 15 genes affecting oil body mobilization, fatty acid β-oxidation, the gly...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.116.193169
更新日期:2016-11-01 00:00:00