Excursions along the Interface between Disruptive and Stabilizing Selection.

Abstract:

:When a polygenic character is exposed to natural selection in which the curve giving fitness as a function of phenotype is a mixture of two Gaussian (normal) curves, the population may respond either by evolving to a specialized phenotype near one of the two optimum phenotypes, or by evolving to a generalized phenotype between them. Using approximate multivariate normal distribution methods, it is demonstrated that the condition for selection to result in a specialized phenotype is that the curve of fitness as a function of breeding value be bimodal. This implies that a specialized phenotype is more likely to result the higher is the heritability of the character. Numerical iterations of four-locus models and algebraic analysis of a symmetric two-locus model generally support the conclusions of the normal approximation.

journal_name

Genetics

journal_title

Genetics

authors

Felsenstein J

subject

Has Abstract

pub_date

1979-11-01 00:00:00

pages

773-95

issue

3

eissn

0016-6731

issn

1943-2631

journal_volume

93

pub_type

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