Four loci on abnormal chromosome 10 contribute to meiotic drive in maize.

Abstract:

:We provide a genetic analysis of the meiotic drive system on maize abnormal chromosome 10 (Ab10) that causes preferential segregation of specific chromosomal regions to the reproductive megaspore. The data indicate that at least four chromosomal regions contribute to meiotic drive, each providing distinct functions that can be differentiated from each other genetically and/or phenotypically. Previous reports established that meiotic drive requires neocentromere activity at specific tandem repeat arrays (knobs) and that two regions on Ab10 are involved in trans-activating neocentromeres. Here we confirm and extend data suggesting that only one of the neocentromere-activating regions is sufficient to move many knobs. We also confirm the localization of a locus/loci on Ab10, thought to be a prerequisite for meiotic drive, which promotes recombination in structural heterozygotes. In addition, we identified two new and independent functions required for meiotic drive. One was identified through the characterization of a deletion derivative of Ab10 [Df(L)] and another as a newly identified meiotic drive mutation (suppressor of meiotic drive 3). In the absence of either function, meiotic drive is abolished but neocentromere activity and the recombination effect typical of Ab10 are unaffected. These results demonstrate that neocentromere activity and increased recombination are not the only events required for meiotic drive.

journal_name

Genetics

journal_title

Genetics

authors

Hiatt EN,Dawe RK

keywords:

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

699-709

issue

2

eissn

0016-6731

issn

1943-2631

journal_volume

164

pub_type

杂志文章

相关文献

GENETICS文献大全
  • Genome properties and prospects of genomic prediction of hybrid performance in a breeding program of maize.

    abstract::Maize (Zea mays L.) serves as model plant for heterosis research and is the crop where hybrid breeding was pioneered. We analyzed genomic and phenotypic data of 1254 hybrids of a typical maize hybrid breeding program based on the important Dent × Flint heterotic pattern. Our main objectives were to investigate genome ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.114.165860

    authors: Technow F,Schrag TA,Schipprack W,Bauer E,Simianer H,Melchinger AE

    更新日期:2014-08-01 00:00:00

  • Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences.

    abstract::Divergence of the hyperthermophilic Archaea, Pyrococcus furiosus and Pyrococcus horikoshii, was assessed by analysis of complete genomic sequences of both species. The average nucleotide identity between the genomic sequences is 70-75% within ORFs. The P. furiosus genome (1.908 mbp) is 170 kbp larger than the P. horik...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Maeder DL,Weiss RB,Dunn DM,Cherry JL,González JM,DiRuggiero J,Robb FT

    更新日期:1999-08-01 00:00:00

  • Sequence diversity, reproductive isolation and species concepts in Saccharomyces.

    abstract::Using the biological species definition, yeasts of the genus Saccharomyces sensu stricto comprise six species and one natural hybrid. Previous work has shown that reproductive isolation between the species is due primarily to sequence divergence acted upon by the mismatch repair system and not due to major gene differ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.106.062166

    authors: Liti G,Barton DB,Louis EJ

    更新日期:2006-10-01 00:00:00

  • Genome analysis of Chlamydomonas reinhardtii reveals the existence of multiple, compartmentalized iron-sulfur protein assembly machineries of different evolutionary origins.

    abstract::The unicellular green alga Chlamydomonas reinhardtii is used extensively as a model to study eukaryotic photosynthesis, flagellar functions, and more recently the production of hydrogen as biofuel. Two of these processes, photosynthesis and hydrogen production, are highly dependent on iron-sulfur (Fe-S) enzymes. To un...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.086033

    authors: Godman J,Balk J

    更新日期:2008-05-01 00:00:00

  • Isolation and gene expression analysis of Arabidopsis thaliana mutants with constitutive expression of ATL2, an early elicitor-response RING-H2 zinc-finger gene.

    abstract::Genes with unstable transcripts often encode proteins that play important regulatory roles. ATL2 is a member of a multigene family coding highly related RING-H2 zinc-finger proteins that may function as E3 ubiquitin ligases. ATL2 mRNA accumulation occurs rapidly and transiently after incubation with elicitors of patho...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.104.028043

    authors: Serrano M,Guzmán P

    更新日期:2004-06-01 00:00:00

  • Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans.

    abstract::Biological robustness, the ability of an organism to maintain a steady-state output as genetic or environmental inputs change, is critical for proper development. MicroRNAs have been implicated in biological robustness mechanisms through their post-transcriptional regulation of genes and gene networks. Previous resear...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.115.179184

    authors: Burke SL,Hammell M,Ambros V

    更新日期:2015-08-01 00:00:00

  • A genome-wide departure from the standard neutral model in natural populations of Drosophila.

    abstract::We analyze nucleotide polymorphism data for a large number of loci in areas of normal to high recombination in Drosophila melanogaster and D. simulans (24 and 16 loci, respectively). We find a genome-wide, systematic departure from the neutral expectation for a panmictic population at equilibrium in natural population...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Andolfatto P,Przeworski M

    更新日期:2000-09-01 00:00:00

  • Inheritance during parthenogenesis in Daphnia magna.

    abstract::Natural populations of Daphnia magna have been found which are polymorphic for electrophoretic variants of supernatant malic dehydrogenase, esterase, and alkaline phosphatase. Using these enzyme variants as genetic markers it has been possible to demonstrate the absence of recombination during parthenogenetic reproduc...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Hebert PD,Ward RD

    更新日期:1972-08-01 00:00:00

  • Statistical tests of neutrality of mutations.

    abstract::Mutations in the genealogy of the sequences in a random sample from a population can be classified as external and internal. External mutations are mutations that occurred in the external branches and internal mutations are mutations that occurred in the internal branches of the genealogy. Under the assumption of sele...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Fu YX,Li WH

    更新日期:1993-03-01 00:00:00

  • Stochastic demography and the neutral substitution rate in class-structured populations.

    abstract::The neutral rate of allelic substitution is analyzed for a class-structured population subject to a stationary stochastic demographic process. The substitution rate is shown to be generally equal to the effective mutation rate, and under overlapping generations it can be expressed as the effective mutation rate in new...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.114.163345

    authors: Lehmann L

    更新日期:2014-05-01 00:00:00

  • On the effect of fluctuating recombination rates on the decorrelation of gene histories in the human genome.

    abstract::We show how to incorporate fluctuations of the recombination rate along the chromosome into standard gene-genealogical models for the decorrelation of gene histories. This enables us to determine how small-scale fluctuations (Poissonian hot-spot model) and large-scale variations (Kong et al. 2002) of the recombination...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.103.018002

    authors: Eriksson A,Mehlig B

    更新日期:2005-02-01 00:00:00

  • The inheritance of chemical phenotype in Cannabis sativa L.

    abstract::Four crosses were made between inbred Cannabis sativa plants with pure cannabidiol (CBD) and pure Delta-9-tetrahydrocannabinol (THC) chemotypes. All the plants belonging to the F(1)'s were analyzed by gas chromatography for cannabinoid composition and constantly found to have a mixed CBD-THC chemotype. Ten individual ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: de Meijer EP,Bagatta M,Carboni A,Crucitti P,Moliterni VM,Ranalli P,Mandolino G

    更新日期:2003-01-01 00:00:00

  • High intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity.

    abstract::Bisphenol A (BPA) is an organic compound to which human populations are ubiquitously exposed. Epidemiological data suggest BPA exposure might be associated with higher rates of diabetes and reproductive anomalies. Health concerns also include transgenerational consequences, but these mechanisms are crudely defined. Si...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.114.163170

    authors: Branco AT,Lemos B

    更新日期:2014-05-01 00:00:00

  • A molecular description of mutations affecting the pollen component of the Nicotiana alata S locus.

    abstract::Mutations affecting the self-incompatibility response of Nicotiana alata were generated by irradiation. Mutants in the M1 generation were selected on the basis of pollen tube growth through an otherwise incompatible pistil. Twelve of the 18 M1 plants obtained from the mutagenesis screen were self-compatible. Eleven se...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Golz JF,Su V,Clarke AE,Newbigin E

    更新日期:1999-07-01 00:00:00

  • The effect of nonhomologous DNA sequences on interplasmidic recombination.

    abstract::The effect of nonhomologous DNA sequences at one or both sides of short genetic intervals on recombination within that interval was investigated, using an interplasmidic recombination system in Escherichia coli K-12. The recombining plasmids were derivatives of pBR322 and pACYC184, which share a 1330-nucleotide sequen...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Laban A,Silberstein Z,Cohen A

    更新日期:1984-09-01 00:00:00

  • Spontaneous mutational effects on reproductive traits of arabidopsis thaliana.

    abstract::A study of spontaneous mutation in Arabidopsis thaliana was initiated from a single inbred Columbia founder; 120 lines were established and advanced 17 generations by single-seed descent. Here, we report an assay of reproductive traits in a random set of 40 lines from generations 8 and 17, grown together at the same t...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Shaw RG,Byers DL,Darmo E

    更新日期:2000-05-01 00:00:00

  • Allele-specific interactions between ttg and gl1 during trichome development in Arabidopsis thaliana.

    abstract::Trichome development in Arabidopsis thaliana is a well-characterized model for the study of plant cell differentiation. Two genes that play an essential role in the initiation of trichome development are GL1 and TTG. Mutations in either gene prevent the initiation of most trichomes. The GL1 gene encodes a myb-related ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Larkin JC,Walker JD,Bolognesi-Winfield AC,Gray JC,Walker AR

    更新日期:1999-04-01 00:00:00

  • Persistence time of loss-of-function mutations at nonessential loci affecting eye color in Drosophila melanogaster.

    abstract::Persistence time of a mutant allele, the expected number of generations before its elimination from the population, can be estimated as the ratio of the number of segregating mutations per individual over the mutation rate per generation. We screened two natural populations of Drosophila melanogaster for mutations cau...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.105.046094

    authors: Yampolsky LY,Allen C,Shabalina SA,Kondrashov AS

    更新日期:2005-12-01 00:00:00

  • Postprocessing of genealogical trees.

    abstract::We consider inference for demographic models and parameters based upon postprocessing the output of an MCMC method that generates samples of genealogical trees (from the posterior distribution for a specific prior distribution of the genealogy). This approach has the advantage of taking account of the uncertainty in t...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.071910

    authors: Meligkotsidou L,Fearnhead P

    更新日期:2007-09-01 00:00:00

  • Point mutation rate of bacteriophage PhiX174.

    abstract::The point mutation rate of phage PhiX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0x10(-6) substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per roun...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.109.106005

    authors: Cuevas JM,Duffy S,Sanjuán R

    更新日期:2009-10-01 00:00:00

  • Pre-Meiotic DNA Synthesis and Recombination in CHLAMYDOMONAS REINHARDI.

    abstract::The time of the pre-meiotic S-period was determined by (32)P incorporation in synchronously germinating zygospores of Chlamydomonas reinhardi at six and one-half to seven hours after the beginning of germination. Phenethyl alcohol treatment caused death of zygospores at a period one hour before the S-period, and also ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Chiu SM,Hastings PJ

    更新日期:1973-01-01 00:00:00

  • P-Element insertion at the polyhomeotic gene leads to formation of a novel chimeric protein that negatively regulates yellow gene expression in P-element-induced alleles of Drosophila melanogaster.

    abstract::Polyhomeotic is a member of the Polycomb group (Pc-G) of homeotic repressors. The proteins encoded by the Pc-G genes form repressive complexes on the polycomb group response element sites. The phP1 mutation was induced by insertion of a 1.2-kb P element into the 5' transcribed nontranslated region of the proximal poly...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Belenkaya T,Soldatov A,Nabirochkina E,Biryukova I,Georgieva S,Georgiev P

    更新日期:1998-10-01 00:00:00

  • Conditions under which genome-wide association studies will be positively misleading.

    abstract::Genome-wide association mapping is a popular method for using natural variation within a species to generate a genotype-phenotype map. Statistical association between an allele at a locus and the trait in question is used as evidence that variation at the locus is responsible for variation of the trait. Indirect assoc...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.110.121665

    authors: Platt A,Vilhjálmsson BJ,Nordborg M

    更新日期:2010-11-01 00:00:00

  • Genome reduction promotes increase in protein functional complexity in bacteria.

    abstract::Obligate pathogenic and endosymbiotic bacteria typically experience gene loss due to functional redundancy, asexuality, and genetic drift. We hypothesize that reduced genomes increase their functional complexity through protein multitasking, in which many genes adopt new roles to counteract gene loss. Comparisons of i...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.112.145656

    authors: Kelkar YD,Ochman H

    更新日期:2013-01-01 00:00:00

  • Correcting the bias of Wright's estimates of the number of genes affecting a quantitative character: a further improved method.

    abstract::Wright's method of estimating the number of genes contributing to the difference in a quantitative character between two populations involves observing the means and variances of the two parental populations and their hybrid populations. Although simple, Wright's method provides seriously biased estimates, largely due...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Zeng ZB

    更新日期:1992-08-01 00:00:00

  • Analysis of chromosomal rearrangements induced by postmeiotic mutagenesis with ethylnitrosourea in zebrafish.

    abstract::Mutations identified in zebrafish genetic screens allow the dissection of a wide array of problems in vertebrate biology. Most screens have examined mutations induced by treatment of spermatogonial (premeiotic) cells with the chemical mutagen N-ethyl-N-nitrosourea (ENU). Treatment of postmeiotic gametes with ENU induc...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Imai Y,Feldman B,Schier AF,Talbot WS

    更新日期:2000-05-01 00:00:00

  • Thermal rescue of UV-irradiated bacteriophage T4 and biphasic mode of action of the WXY system.

    abstract::When ultraviolet-irradiated bacteriophage T4 is assayed at plating temperatures ranging from 20 degrees to 40 degrees, its survival increases at the higher temperatures. This "thermal rescue" requires an intact WXY system but not the denV pyrimidine dimer excision system. Mutation rates decrease with increasing temper...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Conkling MA,Drake JW

    更新日期:1984-08-01 00:00:00

  • An Extension of a Model for the Evolution of Multigene Families by Unequal Crossing over.

    abstract::Evolution of a multigene family is studied from the standpoint of population genetics. It is assumed that the multigene family is undergoing continuous interchromosomal unequal crossing over, mutation and random frequency drift. The equilibrium properties of the probability of gene identity (clonality) are investigate...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Ohta T

    更新日期:1979-03-01 00:00:00

  • Recovery of heritable, transposon-induced, mutant alleles of the rf 2 nuclear restorer of T-cytoplasm maize.

    abstract::T (Texas) cytoplasm is associated with a mitochondrial disruption that is phenotypically expressed during microsporogenesis resulting in male sterility. Restoration of pollen fertility in T-cytoplasm maize is controlled by dominant alleles at two unlinked, complementary, nuclear-encoded genes, rf1 and rf2. As a first ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Schnable PS,Wise RP

    更新日期:1994-03-01 00:00:00

  • The promotion of gonadal cell divisions by the Caenorhabditis elegans TRPM cation channel GON-2 is antagonized by GEM-4 copine.

    abstract::The initiation of postembryonic cell divisions by the gonadal precursors of C. elegans requires the activity of gon-2. gon-2 encodes a predicted cation channel (GON-2) of the TRPM subfamily of TRP proteins and is likely to mediate the influx of Ca(2+) and/or Mg(2+). We report here that mutations in gem-4 (gon-2 extrag...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Church DL,Lambie EJ

    更新日期:2003-10-01 00:00:00