Genetic divergence in mandible form in relation to molecular divergence in inbred mouse strains.

abstract：:Yip1p is the first identified Rab-interacting membrane protein and the founder member of the YIP1 family, with both orthologs and paralogs found in all eukaryotic genomes. The exact role of Yip1p is unclear; YIP1 is an essential gene and defective alleles severely disrupt membrane transport and inhibit ER vesicle budd...

journal_title：Genetics

authors： Chen CZ,Calero M,DeRegis CJ,Heidtman M,Barlowe C,Collins RN

更新日期：2004-12-01 00:00:00

abstract：:The presence of large genomic regions with suppressed recombination (SR) is a key shared property of some sex- and mating-type determining (mat) chromosomes identified to date in animals, plants, and fungi. Why such regions form and how they evolve remain central questions in evolutionary genetics. The smut fungus Mic...

journal_title：Genetics

authors： Whittle CA,Votintseva A,Ridout K,Filatov DA

更新日期：2015-03-01 00:00:00

abstract：:Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variati...

journal_title：Genetics

authors： Berger EM,Weber L

更新日期：1974-12-01 00:00:00

abstract：:To inquire whether the loci identified by recombination-defective and disjunction-defective meiotic mutants in Drosophila are also utilized during mitotic cell division, the effects of 18 meiotic mutants (representing 13 loci) on mitotic chromosome stability have been examined genetically. To do this, meiotic-mutant-b...

journal_title：Genetics

authors： Baker BS,Carpenter AT,Ripoll P

更新日期：1978-11-01 00:00:00

abstract：:Meiosis and spore formation in the yeast Saccharomyces cerevisiae are associated with increased expression of sporulation-specific genes. One of these genes, IME2, encodes a putative protein kinase that is a positive regulator of other sporulation-specific genes. We have isolated mutations that cause reduced expressio...

journal_title：Genetics

authors： Su SS,Mitchell AP

更新日期：1993-01-01 00:00:00

abstract：:The transmission of transposed Ac elements in progeny derived by self-pollination of ten transformed tomato plants has been examined by Southern hybridization analysis. We show that six of these primary transformants have transmitted a transposed Ac to at least one progeny. One of the families was segregating for at l...

journal_title：Genetics

authors： Belzile F,Lassner MW,Tong Y,Khush R,Yoder JI

更新日期：1989-09-01 00:00:00

abstract：:Gain or loss of chromosomes resulting in aneuploidy can be important factors in cancer and adaptive evolution. Although chromosome gain is a frequent event in eukaryotes, there is limited information on its genetic control. Here we measured the rates of chromosome gain in wild-type yeast and sister chromatid cohesion ...

journal_title：Genetics

authors： Covo S,Puccia CM,Argueso JL,Gordenin DA,Resnick MA

更新日期：2014-02-01 00:00:00

abstract：:RecQ helicases function in the maintenance of genome stability in many organisms. The filamentous fungus Neurospora crassa has two RecQ homologs, QDE3 and RECQ2. We found that the qde-3 recQ2 double mutant showed a severe growth defect. The growth defect was alleviated by mutation in mei-3, the homolog of yeast RAD51,...

journal_title：Genetics

authors： Kato A,Inoue H

更新日期：2006-01-01 00:00:00

abstract：:137Cs-gamma irradiation of bacteriophage T4 induces large deletions plus a variety of types of point mutations. All mutations arise with single-hit kinetics, and all by a misrepair process. The estimated point mutation rate is 1.5 X 10(-9) per locus per rad. ...

journal_title：Genetics

authors： Conkling MA,Grunau JA,Drake JW

更新日期：1976-04-01 00:00:00

abstract：:Obtaining accurate estimates of the genetic covariance matrix Sigma(G) for multivariate data is a fundamental task in quantitative genetics and important for both evolutionary biologists and plant or animal breeders. Classical methods for estimating Sigma(G) are well known to suffer from substantial sampling errors; i...

journal_title：Genetics

authors： Meyer K,Kirkpatrick M

更新日期：2010-07-01 00:00:00

abstract：:There are two common alleles at the Amylase-2 locus in populations of Gammarus palustris, the salt marsh amphipod. Intensive sampling of individuals from two localities at Jamaica Bay revealed a consistent pattern of heterozygote deficiency.-Five possible sources of heterozygote deficiency were examined in this study....

journal_title：Genetics

authors： Borowsky R,Borowsky B,Milani H,Greenberg P

更新日期：1985-10-01 00:00:00

abstract：:Genomic integrity is threatened by multiple sources of DNA damage. DNA double-strand breaks (DSBs) are among the most dangerous types of DNA lesions and can be generated by endogenous or exogenous agents, but they can arise also during DNA replication. Sister chromatid recombination (SCR) is a key mechanism for the re...

journal_title：Genetics

authors： Conde F,Refolio E,Cordón-Preciado V,Cortés-Ledesma F,Aragón L,Aguilera A,San-Segundo PA

更新日期：2009-06-01 00:00:00

abstract：:Mitotic interconversion of the mating-type locus (mat1) of the fission yeast Schizosaccharomyces pombe is initiated by a double-strand break at mat1. The mat2 and mat3 loci act as nonrandom donors of genetic information for mat1 switching such that switches occur primarily (or only) to the opposite mat1 allele. Locati...

journal_title：Genetics

authors： Klar AJ,Bonaduce MJ

更新日期：1991-12-01 00:00:00

abstract：:THE FOLLOWING MODELS ARE CONSIDERED FOR THE GENETIC DETERMINATION OF QUANTITATIVE TRAITS: segregation at one locus, at two linked loci, at any number of equal and additive unlinked loci, and at one major locus and an indefinite number of equal and additive loci. In each case an appropriate likelihood is given for data...

journal_title：Genetics

authors： Elston RC,Stewart J

更新日期：1973-04-01 00:00:00

abstract：:A lethal locus (l(2)br7;35B6-10), near Adh on chromosome arm 2L of D. melanogaster, is identified with Plunkett's dominant suppressor of Hairless (H). Of eight new alleles, seven act as dominant suppressors of H, the eighth is a dominant enhancer of H. One of the suppressor alleles is both a leaky lethal and a weak s...

journal_title：Genetics

authors： Ashburner M

更新日期：1982-07-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. While many AMD susceptibility variants have been identified, their influence on AMD progression has not been elucidated. Using data from two large clinical trials, Age-Related Eye Disease Study (AREDS) and AREDS2, we evaluat...

journal_title：Genetics

authors： Ding Y,Liu Y,Yan Q,Fritsche LG,Cook RJ,Clemons T,Ratnapriya R,Klein ML,Abecasis GR,Swaroop A,Chew EY,Weeks DE,Chen W,AREDS2 Research Group.

更新日期：2017-05-01 00:00:00

abstract：:The long-term population genetics of multigene families is influenced by several biased and unbiased mechanisms of nonreciprocal exchanges (gene conversion, unequal exchanges, transposition) between member genes, often distributed on several chromosomes. These mechanisms cause fluctuations in the copy number of varian...

journal_title：Genetics

authors： Ohta T,Dover GA

更新日期：1984-10-01 00:00:00

abstract：:Two sets of overlapping experiments were conducted to examine recombination and spontaneous mutation events within clusters of resistance genes in lettuce. Multiple generations were screened for recombinants using PCR-based markers flanking Dm3. The Dm3 region is not highly recombinagenic, exhibiting a recombination f...

journal_title：Genetics

authors： Chin DB,Arroyo-Garcia R,Ochoa OE,Kesseli RV,Lavelle DO,Michelmore RW

更新日期：2001-02-01 00:00:00

abstract：:The larval body wall muscles of Drosophila melanogaster arise by fusion of founder myoblasts (FMs) and fusion-competent myoblasts (FCMs). Sticks-and-Stones (SNS) is expressed on the surface of all FCMs and mediates adhesion with FMs and developing syncytia. Intracellular components essential for myoblast fusion are th...

journal_title：Genetics

authors： Kocherlakota KS,Wu JM,McDermott J,Abmayr SM

更新日期：2008-03-01 00:00:00

abstract：:Mutants of Paramecium caudatum with abnormal swimming behavior or responses to cations were obtained by mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. Some of the mutants, like pawn in P. tetraurelia, cannot swim backward and are called CNR. Seven independently obtained CNR mutants belonged to three complement...

journal_title：Genetics

authors： Takahashi M

更新日期：1979-03-01 00:00:00

abstract：:Trichome development in Arabidopsis thaliana is a well-characterized model for the study of plant cell differentiation. Two genes that play an essential role in the initiation of trichome development are GL1 and TTG. Mutations in either gene prevent the initiation of most trichomes. The GL1 gene encodes a myb-related ...

journal_title：Genetics

authors： Larkin JC,Walker JD,Bolognesi-Winfield AC,Gray JC,Walker AR

更新日期：1999-04-01 00:00:00

abstract：:Samples of mtDNA isolated from each of 92 lizards representing all color pattern classes of Cnemidophorus tesselatus and two populations of C. tigris marmoratus were digested with the restriction endonucleases MboI, TaqI, RsaI and MspI. The mtDNA fragment sizes were compared after radioactive labeling and gel electrop...

journal_title：Genetics

authors： Densmore LD,Wright JW,Brown WM

更新日期：1985-08-01 00:00:00

abstract：:The parasitoid wasp Nasonia vitripennis is an emerging model organism for developmental and behavioral genetics. It reproduces by haplodiploidy; males typically develop parthenogenetically from haploid eggs and females from fertilized diploid eggs. A polyploid mutant strain is available in which females are triploid a...

journal_title：Genetics

authors： Beukeboom LW,Kamping A

更新日期：2006-02-01 00:00:00

abstract：:Wolbachia-induced cytoplasmic incompatibility (CI) is expressed when infected males are crossed with either uninfected females or females infected with Wolbachia of different CI specificity. In diploid insects, CI results in embryonic mortality, apparently due to the the loss of the paternal set of chromosomes, usuall...

journal_title：Genetics

authors： Zabalou S,Apostolaki A,Pattas S,Veneti Z,Paraskevopoulos C,Livadaras I,Markakis G,Brissac T,Merçot H,Bourtzis K

更新日期：2008-04-01 00:00:00

abstract：:A number of fundamental processes comprise the cell division cycle, including spindle formation, chromosome segregation, and cytokinesis. Our current understanding of these processes has benefited from the isolation and analysis of mutants, with the meiotic divisions in the male germline of Drosophila being particular...

journal_title：Genetics

authors： Afshar K,Gönczy P,DiNardo S,Wasserman SA

更新日期：2001-03-01 00:00:00

abstract：:Samples of Rhynchosporium secalis were collected from two experimental barley populations known to carry a diverse array of alleles for resistance to this fungal pathogen. Classification of 163 isolates for four putative isozyme systems, a colony color dimorphism and 20 ribosomal DNA restriction fragment length varian...

journal_title：Genetics

authors： McDermott JM,McDonald BA,Allard RW,Webster RK

更新日期：1989-07-01 00:00:00

abstract：:Though much has been learned about the process of ovarian follicle maturation through studies of oogenesis in both vertebrate and invertebrate systems, less is known about how follicles form initially. In Drosophila, two somatic follicle stem cells (FSCs) in each ovariole give rise to all polar cells, stalk cells, and...

journal_title：Genetics

authors： Nystul T,Spradling A

更新日期：2010-02-01 00:00:00

abstract：:The small heat-shock proteins have undergone a tremendous diversification in plants; whereas only a single small heat-shock protein is found in fungi and many animals, over 20 different small heat-shock proteins are found in higher plants. The small heat-shock proteins in plants have diversified in both sequence and c...

journal_title：Genetics

authors： Waters ER

更新日期：1995-10-01 00:00:00

abstract：:The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis. Kinetochore orientation is generated in part by a process of resolving kinetochores at the centromere (centromere resolution) prior to spindle interactions. Because few of the genes required for ce...

journal_title：Genetics

authors： Stanvitch G,Moore LL

更新日期：2008-01-01 00:00:00

abstract：:A novel method of RNA secondary structure prediction based on a comparison of nucleotide sequences is described. This method correctly predicts nearly all evolutionarily conserved secondary structures of five different RNAs: tRNA, 5S rRNA, bacterial ribonuclease P (RNase P) RNA, eukaryotic small subunit rRNA, and the ...

journal_title：Genetics

authors： Parsch J,Braverman JM,Stephan W

更新日期：2000-02-01 00:00:00