Management of subdivided populations in conservation programs: development of a novel dynamic system.

abstract：:New rudimentary (r) mutants have been isolated following mutagenesis with ethyl methanesulfonate (r(LE)), ICR-170 (r(LI)) and X rays (r(LX)). From wing phenotype measurements on homoallelic females, it has been shown that the r(LE) mutant series includes several leaky alleles, as well as alleles that produce moderate ...

journal_title：Genetics

authors： Rawls JM,Porter LA

更新日期：1979-09-01 00:00:00

abstract：:Dna2 is a nuclease and helicase that functions redundantly with other proteins in Okazaki fragment processing, double-strand break resection, and checkpoint kinase activation. Dna2 is an essential enzyme, required for yeast and mammalian cell viability. Here, we report that numerous mutations affecting the DNA damage ...

journal_title：Genetics

authors： Markiewicz-Potoczny M,Lisby M,Lydall D

更新日期：2018-05-01 00:00:00

abstract：:Mutations identified in zebrafish genetic screens allow the dissection of a wide array of problems in vertebrate biology. Most screens have examined mutations induced by treatment of spermatogonial (premeiotic) cells with the chemical mutagen N-ethyl-N-nitrosourea (ENU). Treatment of postmeiotic gametes with ENU induc...

journal_title：Genetics

authors： Imai Y,Feldman B,Schier AF,Talbot WS

更新日期：2000-05-01 00:00:00

abstract：:In the Brassicaceae, self-vs. nonself-recognition in self-incompatibility is controlled by sporophytic S-alleles. Haplotypes specifying both SRK (S-receptor kinase) and SLG (S-locus glycoprotein) are considered to play an important role in the recognition reactions. We compared the nucleotide sequences of SRK9(Bc) and...

journal_title：Genetics

authors： Hinata K,Watanabe M,Yamakawa S,Satta Y,Isogai A

更新日期：1995-07-01 00:00:00

abstract：:Three previously described genes, enhancer of yellow, 1, 2 and 3, are shown to cooperate with the zeste gene in the control of white gene expression. The mutations e(y)1u1, e(y)3u1, and to a lesser extent e(y)2u1, enhance the effect of the zeste null allele zv77h. Different combinations of e(y)1u1, e(y)2u1 and e(y)3u1...

journal_title：Genetics

authors： Georgiev PG

更新日期：1994-11-01 00:00:00

abstract：:Genetic study of the reproductive barriers between related species plays an essential role in understanding the process of speciation. We developed a new method for mapping all possible factors causing deviations from expected Mendelian segregation ratios in F(2) progeny, which substantially contribute to reproductive...

journal_title：Genetics

authors： Harushima Y,Nakagahra M,Yano M,Sasaki T,Kurata N

更新日期：2001-10-01 00:00:00

abstract：:Drosophila melanogaster males deficient for the crystal (cry) locus of the Y chromosome that carry between 15 and 60 copies of the X-linked Stellate (Ste) gene are semisterile, have elevated levels of nondisjunction, produce distorted sperm genotype ratios (meiotic drive), and evince hyperactive transcription of Ste i...

journal_title：Genetics

authors： Belloni M,Tritto P,Bozzetti MP,Palumbo G,Robbins LG

更新日期：2002-08-01 00:00:00

abstract：:Regulatory networks provide control over complex cell behavior in all kingdoms of life. Here we describe a statistical model, based on representing proteins as collections of domains or motifs, which predicts unknown molecular interactions within these biological networks. Using known protein-protein interactions of S...

journal_title：Genetics

authors： Gomez SM,Lo SH,Rzhetsky A

更新日期：2001-11-01 00:00:00

abstract：:The homeotic genes of the Drosophila bithorax complex are controlled by a large cis-regulatory region that ensures their segmentally restricted pattern of expression. A deletion that removes the Frontabdominal-7 cis-regulatory region (Fab-7') dominantly transforms parasegment 11 into parasegment 12. Previous studies s...

journal_title：Genetics

authors： Hagstrom K,Muller M,Schedl P

更新日期：1997-08-01 00:00:00

abstract：:Cell diversity in multicellular organisms relies on coordination between cell proliferation and the acquisition of cell identity. The equilibrium between these two processes is essential to assure the correct number of determined cells at a given time at a given place. Using genetic approaches and correlative microsco...

journal_title：Genetics

authors： Simon F,Ramat A,Louvet-Vallée S,Lacoste J,Burg A,Audibert A,Gho M

更新日期：2019-07-01 00:00:00

abstract：:Our understanding of the cellular mechanisms by which animals regulate their response to starvation is limited, despite the strong relevance of the problem to major human health issues. The L1 diapause of Caenorhabditis elegans, where first-stage larvae arrest in response to a food-less environment, is an excellent sy...

journal_title：Genetics

authors： Cui M,Wang Y,Cavaleri J,Kelson T,Teng Y,Han M

更新日期：2017-02-01 00:00:00

abstract：:We describe a fast hierarchical Bayesian method for mapping quantitative trait loci by haplotype-based association, applicable when haplotypes are not observed directly but are inferred from multiple marker genotypes. The method avoids the use of a Monte Carlo Markov chain by employing priors for which the likelihood ...

journal_title：Genetics

authors： Durrant C,Mott R

更新日期：2010-03-01 00:00:00

abstract：:Cornell Control White Leghorn chicks were grown in a common environment to five weeks of age and selected for fast and slow gain in body weight from five to nine weeks of age at two temperatures, 21.1 degrees (cold) and 32.2 degrees (hot), during which time a constant 50% relative humidity was maintained. All lines we...

journal_title：Genetics

authors： Bohren BB,Carson JR,Rogler JC

更新日期：1981-02-01 00:00:00

abstract：:Hotspots regulate the position and frequency of Spo11 (Rec12)-initiated meiotic recombination, but paradoxically they are suicidal and are somehow resurrected elsewhere in the genome. After the DNA sequence-dependent activation of hotspots was discovered in fission yeast, nearly two decades elapsed before the key real...

journal_title：Genetics

authors： Wahls WP,Davidson MK

更新日期：2011-11-01 00:00:00

abstract：:A number of fundamental processes comprise the cell division cycle, including spindle formation, chromosome segregation, and cytokinesis. Our current understanding of these processes has benefited from the isolation and analysis of mutants, with the meiotic divisions in the male germline of Drosophila being particular...

journal_title：Genetics

authors： Afshar K,Gönczy P,DiNardo S,Wasserman SA

更新日期：2001-03-01 00:00:00

abstract：:Selection during evolution, whether natural or artificial, acts through the phenotype. For multifaceted phenotypes such as plant and inflorescence architecture, the underlying genetic architecture is comprised of a complex network of interacting genes rather than single genes that act independently to determine the tr...

journal_title：Genetics

authors： Studer AJ,Wang H,Doebley JF

更新日期：2017-10-01 00:00:00

abstract：:As a genetic mutation is passed down across generations, it distinguishes those genomes that have inherited it from those that have not, providing a glimpse of the genealogical tree relating the genomes to each other at that site. Statistical summaries of genetic variation therefore also describe the underlying geneal...

journal_title：Genetics

authors： Ralph P,Thornton K,Kelleher J

更新日期：2020-07-01 00:00:00

abstract：:USING A NEWLY DEVELOPED PLATING SYSTEM, WE HAVE MEASURED CELL SURVIVAL AND THE FREQUENCIES OF VARIATION IN AN INHERITED TRAIT AFTER TREATMENT OF SOYBEAN CELL SUSPENSIONS WITH DIFFERENT MUTAGENS: ethyl methanesulfonate (EMS), methyl methanesulfonate (MMS), N-Methyl-N'-nitro-N-nitroso-guanidine (MNNG), hycanthone (1-{[2...

journal_title：Genetics

authors： Weber G,Lark KG

更新日期：1980-09-01 00:00:00

abstract：:The size of the genome in the opportunistic fungus Candida albicans is 15.6 Mb. Whole-genome shotgun sequencing was carried out at Stanford University where the sequences were assembled into 412 contigs. C. albicans is a diploid basically, and analysis of the sequence is complicated due to repeated sequences and to se...

journal_title：Genetics

authors： Chibana H,Oka N,Nakayama H,Aoyama T,Magee BB,Magee PT,Mikami Y

更新日期：2005-08-01 00:00:00

abstract：:Magnesium (Mg) is an essential enzyme cofactor and a key structural component of biological molecules, but relatively little is known about the molecular components required for Mg homeostasis in eukaryotic cells. The yeast genome encodes four characterized members of the CorA Mg transporter superfamily located in the...

journal_title：Genetics

authors： Pisat NP,Pandey A,Macdiarmid CW

更新日期：2009-11-01 00:00:00

abstract：:The interval mapping method is widely used for the mapping of quantitative trait loci (QTLs) in segregating generations derived from crosses between inbred lines. The efficiency of detecting and the accuracy of mapping multiple QTLs by using genetic markers are much increased by employing multiple QTL models instead o...

journal_title：Genetics

authors： Jansen RC

更新日期：1993-09-01 00:00:00

abstract：:In California, Drosophila simulans females from some populations (type W) produce relatively few adult progeny when crossed to males from some other populations (type R), but the productivity of the reciprocal cross is comparable to within-population controls. These two incompatibility types are widespread in North Am...

journal_title：Genetics

authors： Hoffmann AA,Turelli M

更新日期：1988-06-01 00:00:00

abstract：:Rare genetic variants have recently been studied for genome-wide associations with human complex diseases. Existing rare variant methods are based on the hypothesis-testing framework that predefined variant sets need to be tested separately. The power of those methods is contingent upon accurate selection of variants ...

journal_title：Genetics

authors： Zhang Y,Ghosh S,Hakonarson H

更新日期：2014-11-01 00:00:00

abstract：:A semi-lethal, sterile allele of the smooth locus (2-91.5), sm3, was discovered in an artificial selection line for low abdominal bristle number that had been started from a P-M dysgenic cross. The fitness effects and extremely low bristle number phenotype of the allele could not be separated by recombination from a P...

journal_title：Genetics

authors： zur Lage P,Shrimpton AD,Flavell AJ,Mackay TF,Brown AJ

更新日期：1997-06-01 00:00:00

abstract：:Sex differences occur in most species and affect a variety of biological traits including morphology, behavior, and life history. The nematode Caenorhabditis elegans exists as a population of self-fertile hermaphrodites with occasional males, which differ anatomically and behaviorally from hermaphrodites. Here we show...

journal_title：Genetics

authors： van den Berg MC,Woerlee JZ,Ma H,May RC

更新日期：2006-06-01 00:00:00

abstract：:The third hypervariable (V3) region of the HIV-1 gp120 protein is responsible for many aspects of viral infectivity. The tertiary structure of the V3 loop seems to influence the coreceptor usage of the virus, which is an important determinant of HIV pathogenesis. Hence, the information about preferred conformations of...

journal_title：Genetics

authors： Watabe T,Kishino H,Okuhara Y,Kitazoe Y

更新日期：2006-03-01 00:00:00

abstract：:Mating behavior in adult male nematodes can be assayed by mating efficiency, i.e., the number of cross progeny sired by males under standard conditions. Mutant males from 220 strains, representing most of the known complementation groups of C. elegans, have been examined for mating efficiency and for anatomical abnorm...

journal_title：Genetics

authors： Hodgkin J

更新日期：1983-01-01 00:00:00

abstract：:Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In Caenorhabditis elegans, a specialized condensin, which forms the core of the dosage compensation complex (DCC), binds to and represses X chromosome t...

journal_title：Genetics

authors： Street LA,Morao AK,Winterkorn LH,Jiao CY,Albritton SE,Sadic M,Kramer M,Ercan S

更新日期：2019-07-01 00:00:00

abstract：:In Drosophila and other insects egg production is related to the nutrients available. Somehow the nutritional status of the environment is translated into hormonal signs that can be "read" by each individual egg chamber, influencing the decision to either develop into an egg or die. We have shown that BR-C is a contro...

journal_title：Genetics

authors： Terashima J,Bownes M

更新日期：2004-08-01 00:00:00

abstract：:This study attempted to assay the zygotic contribution of X chromosome genes to the genetic control of embryonic morphogenesis in Drosophila melanogaster. A systematic screen for X-linked genes which affect the morphology of the embryo was undertaken, employing the phenotype of whole mount embryos as the major screeni...

journal_title：Genetics

authors： Eberl DF,Hilliker AJ

更新日期：1988-01-01 00:00:00