Xanthogranulomatous hypophysitis mimicking a pituitary neoplasm.

abstract：:The diagnosis of follicular-patterned carcinomas, including follicular thyroid carcinoma, oncocytic (Hürthle cell) carcinoma, and the encapsulated follicular variant of papillary thyroid carcinoma, requires evidence of capsular and/or vascular invasion. With minimally invasive carcinomas classified often within less t...

journal_title：Endocrine pathology

authors： Glomski K,Nosé V,Faquin WC,Sadow PM

更新日期：2017-06-01 00:00:00

abstract：:Aldosterone-producing adenoma (APA) consisting of pure zona glomerulosa (ZG)-type cells is extremely rare, and primary aldosteronism complicated by pregnancy is also rare. We report a case of APA discovered in a 32-year-old pregnant woman who visited our hospital for hypertension and hypokalemia at 26 weeks gestation....

journal_title：Endocrine pathology

authors： Shigematsu K,Nishida N,Sakai H,Igawa T,Suzuki S,Kawai K,Takahara O

更新日期：2009-04-01 00:00:00

abstract：:Pediatric adrenocortical carcinoma is extremely rare with a prevalence of 0.3 per million. Adrenocortical neoplasms in children usually present with one of the endocrine abnormalities. Adrenocortical neoplasms cannot be easily diagnosed on cytopathology; hence, the cytomorphological features posing diagnostic dilemmas...

journal_title：Endocrine pathology

authors： Agarwal S,Agarwal K

更新日期：2011-03-01 00:00:00

abstract：:The incidence and histology of cysts in the adenohypophysis of adult male Wistar rats are reported. Of sixty pituitaries studied 13 of them (21.6%) presented a single cyst located in the pars distalis. The cysts varied in shape and size and were usually multilocular. Two of them were connected with the subdural space ...

journal_title：Endocrine pathology

authors： Quintanar-Stephano A,Muñoz Fernández L,Quintanar JL,Kovacs K

更新日期：2001-04-01 00:00:00

abstract：:Thirteen cases of fatal sporadic medullary carcinoma of the thyroid (MCT) that killed the patient within 1 year after diagnosis were compared with 12 nonfatal MCTs with excellent prognosis. Males predominated in fatal cases whereas the reverse was true in MCTs with good prognosis. The two groups of tumors showed gener...

journal_title：Endocrine pathology

authors： Harach HR,Bergholm U

更新日期：1993-03-01 00:00:00

abstract：:Various ultrasonographic characteristics of thyroid nodules have been associated with a higher likelihood of malignancy, and certain clinical features may also increase the likelihood of malignancy in patients. This study is designed to determine the ultrasonographic and clinical predictors of malignancy in the atypia...

journal_title：Endocrine pathology

authors： Carr R,Ustun B,Chhieng D,Schofield K,Theoharis C,Hammers L,Adeniran AJ

更新日期：2013-06-01 00:00:00

abstract：:Somatostatin and its analogs have been included in experimental treatment protocols for advanced pancreatic adenocarcinoma based on their known antisecretory and antiproliferative properties. Somatostatin receptor type 2 (sstr2A) mediates antiproliferative actions of somatostatin and has the strongest affinity to the ...

journal_title：Endocrine pathology

authors： Pilichowska M,Kimura N,Schindler M,Kobari M

更新日期：2001-07-01 00:00:00

abstract：:The histological pattern and the cell proliferative activity (as detected by Ki-67 immunostaining) of a series of 50 parathyroid hyperplasias (PTHs) secondary to renal failure were studied to assess their value in predicting recurrence of hyperparathyrodism (HPT). On account of their clinical evolution, these cases we...

journal_title：Endocrine pathology

authors： Abbona G,Papotti M,Gasparri G,Bussolati G

更新日期：1996-04-01 00:00:00

abstract：:Efforts to understand the pathobiology of pheochromocytomas and extra-adrenal paragangliomas have been spurred by genetic and gene expression profiling studies showing genotype-phenotype correlations in familial pheochromocytoma/paraganglioma syndromes and in some sporadic tumors. The current challenge is to relate ca...

journal_title：Endocrine pathology

authors： Tischler AS

更新日期：2006-01-01 00:00:00

abstract：:Gain-of-function germline mutations of the RET proto-oncogene are responsible for initiation of carcinogenesis within the thyroid gland and development of hereditary form of medullary thyroid carcinoma and MEN2 syndrome. Genotype-phenotype correlations are established for most RET mutations, but the importance of the ...

journal_title：Endocrine pathology

authors： Sromek M,Czetwertyńska M,Tarasińska M,Janiec-Jankowska A,Zub R,Ćwikła M,Nowakowska D,Chechlińska M

更新日期：2017-09-01 00:00:00

abstract：:In the majority of cases, Cushing's disease is the result of a small basophilic corticotroph microadenoma with an average size of less than 5 mm. Transsphenoidal microsurgery can cure patients with Cushing's disease; however, selective removal of the lesion requires precise preoperative localization. In this article, ...

journal_title：Endocrine pathology

authors： Booth GL,Smyth HS,Kovacs K,Horvath E,Asa SL,Ezzat S

更新日期：1999-06-01 00:00:00

abstract：:The expression of programmed death-ligand 1 (PD-L1) is an established prerequisite for the administration of checkpoint inhibitor therapy and is of prognostic value in several cancer types. Data concerning the potential effect of PD-L1 on the prognosis of thyroid carcinoma are limited. Therefore, this study aimed to p...

journal_title：Endocrine pathology

authors： Girolami I,Pantanowitz L,Mete O,Brunelli M,Marletta S,Colato C,Trimboli P,Crescenzi A,Bongiovanni M,Barbareschi M,Eccher A

更新日期：2020-09-01 00:00:00

abstract：:Neuroendocrine pancreatic tumors (PanNETs) are graded on the basis of their proliferative activity. Cytological samples are commonly the only samples available, but the determination of Ki-67 in cytology and its reliability as a measure of tumor mitotic activity is not well settled. We have retrospectively reviewed al...

journal_title：Endocrine pathology

authors： Díaz Del Arco C,Díaz Pérez JÁ,Ortega Medina L,Sastre Valera J,Fernández Aceñero MJ

更新日期：2016-12-01 00:00:00

abstract：:Immunohistochemical staining for parathyroid hormone-related protein (PTHrp) was investigated on cryosections of 17 normal-sized human parathyroid glands, 47 adenomatous and hyperplastic glands of hypercalcemic patients with primary or uremic hyperparathyroidism, and 5 metastases of parathyroid carcinoma. Utilizing a ...

journal_title：Endocrine pathology

authors： Hellman P,Bjerneroth G,Juhlin C,Ridefelt P,Rastad J,Åkerström G,Jüppner H

更新日期：1990-09-01 00:00:00

abstract：:This study compared the expression profile of HBME-1 and claudin-1 in 90 papillary thyroid carcinomas (PTCs) with respect to the tumor architecture and invasive growth as reflected in 46 BRAF-like, 31 non-invasive RAS, and 13 invasive RAS-like phenotypes. Individual tumors were given an expression score (max 300) by m...

journal_title：Endocrine pathology

authors： Gucer H,Bagci P,Bedir R,Sehitoglu I,Mete O

更新日期：2016-09-01 00:00:00

abstract：:Goblet cell carcinoid (GCC) of the appendix is a rare entity, of which both the histogenesis and biologic behavior remain controversial, and prognostic tools and therapeutic strategies for this unusual tumor have yet to be defined. The aim of this study was to analyze expression of E-cadherin and b-catenin in GCCs of ...

journal_title：Endocrine pathology

authors： Li CC,Hirowaka M,Qian ZR,Xu B,Sano T

更新日期：2002-04-01 00:00:00

abstract：:Oncocytic phaeochromocytomas are exceedingly rare tumours. To date, there are three reported cases in the literature. This report describes a case of adrenal oncocytic phaeochromocytoma with unique features and malignant potential in a 68-year-old man. The patient presented with an incidental non-functional mass disco...

journal_title：Endocrine pathology

authors： Kasem K,Lam AK

更新日期：2014-12-01 00:00:00

abstract：:Thyroid carcinoma is the most common malignancy of the endocrine system worldwide, but its molecular mechanisms remain unclear. Some diseases are associated with TEKT4 gene. However, its role in thyroid carcinoma has yet to be fully examined. This study was designed to investigate the function of TEKT4 in papillary th...

journal_title：Endocrine pathology

authors： Zheng Z,Zhou X,Cai Y,Chen E,Zhang X,Wang O,Wang Q,Liu H

更新日期：2018-12-01 00:00:00

abstract：:Nonradioisotopic electron microscopic (EM) in situ hybridization (ISH) (EM-SH) with biotinylated oligonucleotide probes is utilized for the ultrastructural visualization of pituitary hormone mRNA in rat pituitary cells. EMISH is an important tool for clarifying the intracellular localization of mRNA and the exact site...

journal_title：Endocrine pathology

authors： Matsuno A,Itoh J,Osamura RY,Watanabe K,Nagashima T

更新日期：1999-10-01 00:00:00

abstract：:Neoplastic plasma cell involvement of thyroid is an uncommon condition, and it may involve thyroid in multiple myeloma or solitary plasmacytoma. Its clinical and pathological features are not well understood. We present a rare case of synchronous thyroid involvement in plasma cell leukemia presenting as thyroid nodule...

journal_title：Endocrine pathology

authors： Tandon A,Paul TR,Singh R,Narendra AM

更新日期：2015-12-01 00:00:00

abstract：:The diagnosis of pituitary corticotroph adenoma relies on the demonstration of a loss of the normal feedback control of adrenocorticotropic hormone (ACTH) biosynthesis by cortisol. The marked variability in the degree of ACTH suppression by glucocorticoids in these tumors, however, greatly enhances the difficulty in d...

journal_title：Endocrine pathology

authors： Franscella S,Favrod-Coune CA,Pizzolato G,Asa SL,Gaillard R,Berney J,Philippe J

更新日期：1991-06-01 00:00:00

abstract：:The question of whether thyroxine (T(4)) and thyrotropin-releasing hormone (TRH) affect mitoses in pituitary thyrotrophs (Tt) and somatotrophs (St) of hypothyroid rats was investigated. Fifteen day thyroidectomized (Tx) rats were used. Groups of Tx animals received T(4) or TRH or both. Except 6 and 24 h TRH groups, th...

journal_title：Endocrine pathology

authors： Quintanar-Stephano A,Valverde-R C,Kovacs K

更新日期：1999-01-01 00:00:00

abstract：:Pheochromocytoma is a catecholamine (CA)-producing tumor that is classified into two types: the norepinephrine (NE) and the mixed NE and epinephrine type (E-type) from plasma CA levels. Phenylethanolamine N-methyltransferase (PNMT) is the terminal enzyme in CA synthesis; it catalyzes the synthesis of E from NE. It is ...

journal_title：Endocrine pathology

authors： Kimura N,Togo A,Sugimoto T,Nata K,Okamoto H,Nagatsu I,Nagura H

更新日期：1996-07-01 00:00:00

abstract：:Tissue sections from 50 cases with thyroid tumors, composed of 11 follicular adenomas, 10 follicular carcinomas, 14 papillary carcinomas, 10 anaplastic carcinomas, and 5 medullary carcinomas, were immunohistochemically analyzed for representative neuroendocrine markers. Immunoexpression ratios of these neuroendocrine ...

journal_title：Endocrine pathology

authors： Satoh F,Umemura S,Yasuda M,Osamura RY

更新日期：2001-10-01 00:00:00

abstract：:A case of localized adiposity of the thyroid in a 35-year-old woman with a long history of steroid therapy for nephrotic syndrome is reported. A well-demarcated yellowish mass measuring 2 cm in diameter was found in the upper portion of the right lobe of the thyroid. Microscopically, this lesion was composed of mature...

journal_title：Endocrine pathology

authors： Morizumi H,Sano T,Tsuyuguchi M,Yoshinarl T,Morimoto S

更新日期：1991-12-01 00:00:00

abstract：:The history of pituitary pathology is a long one that dates back to biblical times, but the last 25 years have represented an era of "coming of age." The role of the pituitary in health and disease was the subject of many studies over the last century. With the development of electron microscopy, immunoassays, and imm...

journal_title：Endocrine pathology

authors： Asa SL,Mete O

更新日期：2014-03-01 00:00:00

abstract：:The relationship between chronic lymphocytic thyroiditis (CLT) and papillary thyroid carcinoma (PTC) is a subject of controversy. Some investigators suggest a causal relationship, whereas others regard the two as only a coincidental occurrence. An additional complicating factor is the presence of atypical nuclei frequ...

journal_title：Endocrine pathology

authors： Hunt JL,Baloch ZW,Barnes L,Swalsky PA,Trusky CL,Sesatomi E,Finkelstein S,LiVolsi VA

更新日期：2002-01-01 00:00:00

abstract：:Molecular tests and mutational panels such as Afirma Gene Expression Classifier (GEC) and ThyroSeq, respectively, have been used to help risk stratify cytologically indeterminate thyroid nodules with the aim to reduce unnecessary surgeries. We studied the effect of molecular testing on the rate of surgical resection i...

journal_title：Endocrine pathology

authors： Jug R,Parajuli S,Ahmadi S,Jiang XS

更新日期：2019-06-01 00:00:00

abstract：:Folliculostellate (FS) cells are present in the anterior pituitary and have important regulatory functions including controlling hormone release from other anterior pituitary cells. FS cells do not usually express neuroendocrine genes such as chromogranin A (CgA). We analyzed transcriptional regulation and gene expres...

journal_title：Endocrine pathology

authors： Stilling GA,Bayliss JM,Jin L,Zhang H,Lloyd RV

更新日期：2005-10-01 00:00:00

abstract：:Twenty-four acromegalic patients were treated with octreotide subcutaneously for periods of 3 to 6 weeks (group I, 12 cases) or 6 months (group II, 12 cases) before transsphenoidal surgery. Radiological studies performed in 19 patients before and at the end of this treatment period revealed no changes in 8 cases. In 8...

journal_title：Endocrine pathology

authors： Beckers A,Kovacs K,Horvath E,Abs R,Reznik M,Stevenaert A

更新日期：1991-09-01 00:00:00