Cysts in the rat adenohypophysis: incidence and histology.

abstract：:The purpose of this study is to describe a case of concurrent medullary and papillary thyroid carcinoma (MTC and PTC) and cutaneous melanoma and to analyze BRAF(V600E) mutation in plasma and tissues. We report the clinical history and the laboratory, imaging, and histopathological findings of a 47-year-old man affecte...

journal_title：Endocrine pathology

authors： Fibbi B,Pinzani P,Salvianti F,Rossi M,Petrone L,De Feo ML,Panconesi R,Vezzosi V,Bianchi S,Simontacchi G,Mangoni M,Pertici M,Forti G,Pupilli C

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) is an uncommon tumor making up about 2% of all papillary thyroid carcinomas. Previous studies have not comprehensively evaluated these tumors in a large series of patients. DESIGN:Twenty-two cases of DSV-PTC diagnosed between 1970 and 2...

journal_title：Endocrine pathology

authors： Thompson LD,Wieneke JA,Heffess CS

更新日期：2005-01-01 00:00:00

abstract：:Approximately 90% of neoplasms found in the sellar region are adenoma of the pituitary gland. The use of frozen sections for the diagnosis of pituitary adenomas has an accuracy of 90% and is useful in evaluating complete tumor removal. However, it is sometimes difficult to diagnose pituitary adenomas using frozen sect...

journal_title：Endocrine pathology

authors： Noh S,Kim SH,Cho NH,Kim SH

更新日期：2015-05-01 00:00:00

abstract：:Neuroendocrine pancreatic tumors (PanNETs) are graded on the basis of their proliferative activity. Cytological samples are commonly the only samples available, but the determination of Ki-67 in cytology and its reliability as a measure of tumor mitotic activity is not well settled. We have retrospectively reviewed al...

journal_title：Endocrine pathology

authors： Díaz Del Arco C,Díaz Pérez JÁ,Ortega Medina L,Sastre Valera J,Fernández Aceñero MJ

更新日期：2016-12-01 00:00:00

abstract：:Various ultrasonographic characteristics of thyroid nodules have been associated with a higher likelihood of malignancy, and certain clinical features may also increase the likelihood of malignancy in patients. This study is designed to determine the ultrasonographic and clinical predictors of malignancy in the atypia...

journal_title：Endocrine pathology

authors： Carr R,Ustun B,Chhieng D,Schofield K,Theoharis C,Hammers L,Adeniran AJ

更新日期：2013-06-01 00:00:00

abstract：:Goblet cell carcinoid (GCC) of the appendix is a rare entity, of which both the histogenesis and biologic behavior remain controversial, and prognostic tools and therapeutic strategies for this unusual tumor have yet to be defined. The aim of this study was to analyze expression of E-cadherin and b-catenin in GCCs of ...

journal_title：Endocrine pathology

authors： Li CC,Hirowaka M,Qian ZR,Xu B,Sano T

更新日期：2002-04-01 00:00:00

abstract：:Synchronous occurrence of medullary and papillary carcinoma of the thyroid gland is very rare. We describe two cases of synchronous medullary and papillary carcinoma of the thyroid. In both cases, medullary carcinoma and papillary carcinoma were separate in the thyroid but mixed in some of the lymph node metastases. A...

journal_title：Endocrine pathology

authors： Seki T,Kameyama K,Hayashi H,Nagahama M,Masudo K,Fukunari N,Tanaka K,Sugino K,Ito K,Takami H

更新日期：2004-04-01 00:00:00

abstract：:In the majority of cases, Cushing's disease is the result of a small basophilic corticotroph microadenoma with an average size of less than 5 mm. Transsphenoidal microsurgery can cure patients with Cushing's disease; however, selective removal of the lesion requires precise preoperative localization. In this article, ...

journal_title：Endocrine pathology

authors： Booth GL,Smyth HS,Kovacs K,Horvath E,Asa SL,Ezzat S

更新日期：1999-06-01 00:00:00

abstract：:Objective. Information on angiogenesis in parathyroid pathology is scanty and in particular no data are available in parathyroid carcinomas. The aim of this study was to analyze angiogenesis as microvascular density (MVD) in parathyroid neoplastic progression from normal gland to adenoma and carcinoma. Methods. Sectio...

journal_title：Endocrine pathology

authors： Viacava P,Bocci G,Fanelli G,Cetani F,Marcocci C,Bevilacqua G,Naccarato AG

更新日期：2006-07-01 00:00:00

abstract：:Nodular corticotrope hyperplasia is a rare pathology causing Cushing's syndrome owing to a primary pituitary disease or ectopic CRH production. In this study, we evaluated the laboratory and pathological findings and results of transsphenoidal pituitary surgery in four patients with Cushing's disease. Dynamic tests of...

journal_title：Endocrine pathology

authors： Salgado LR,Mendonca BB,Goldman J,Semer M,Knoepfelmacher M,Tsanaclis AM,Wajchenberg BL,Liberman B

更新日期：1995-04-01 00:00:00

abstract：:Metallothionein-3 (MT-3) is an intracellular, low molecular weight protein mainly distributed in the central nervous system but also in various peripheral organs and several types of human neoplasms. However, details of MT-3 expression have not been examined in human adrenal cortex and its disorders. The mRNA levels o...

journal_title：Endocrine pathology

authors： Felizola SJ,Nakamura Y,Arata Y,Ise K,Satoh F,Rainey WE,Midorikawa S,Suzuki S,Sasano H

更新日期：2014-09-01 00:00:00

abstract：:This study compared the expression profile of HBME-1 and claudin-1 in 90 papillary thyroid carcinomas (PTCs) with respect to the tumor architecture and invasive growth as reflected in 46 BRAF-like, 31 non-invasive RAS, and 13 invasive RAS-like phenotypes. Individual tumors were given an expression score (max 300) by m...

journal_title：Endocrine pathology

authors： Gucer H,Bagci P,Bedir R,Sehitoglu I,Mete O

更新日期：2016-09-01 00:00:00

abstract：:Extranodal extension (ENE) is a prognostic indicator of aggressiveness for papillary thyroid cancer (PTC). The association between the size of metastatic nodes and the prevalence of ENE has not been previously explored. However, there is a common belief that small lymph nodes with metastatic disease do not significant...

journal_title：Endocrine pathology

authors： Rowe ME,Ozbek U,Machado RA,Yue LE,Hernandez-Prera JC,Valentino A,Qazi M,Brandwein-Weber M,Liu X,Wenig BM,Urken ML

更新日期：2018-03-01 00:00:00

abstract：:Small cell carcinomas may occur in the thyroid gland. Infrequently, they are primary tumors, and have been interpreted as variants of medullary thyroid carcinoma. However, the vast majority of small cell carcinomas involving the thyroid gland are metastatic tumors. In some cases, demonstration of the primary tumor is ...

journal_title：Endocrine pathology

authors： Puente S,Velasco A,Gallel P,Pallares J,Perez-Ruiz L,Ros S,Maravall J,Matias-Guiu X

更新日期：2008-10-01 00:00:00

abstract：:The relationship between chronic lymphocytic thyroiditis (CLT) and papillary thyroid carcinoma (PTC) is a subject of controversy. Some investigators suggest a causal relationship, whereas others regard the two as only a coincidental occurrence. An additional complicating factor is the presence of atypical nuclei frequ...

journal_title：Endocrine pathology

authors： Hunt JL,Baloch ZW,Barnes L,Swalsky PA,Trusky CL,Sesatomi E,Finkelstein S,LiVolsi VA

更新日期：2002-01-01 00:00:00

abstract：:Granular cell tumours of the thyroid gland are rare, with only six previously reported cases in the English literature. Current histological, immunohistochemical and electron microscopic evidence favours a neural/Schwannian relationship. A case of a granular cell tumour of the thyroid gland in a healthy 36-year-old wo...

journal_title：Endocrine pathology

authors： Bowry M,Almeida B,Jeannon JP

更新日期：2011-03-01 00:00:00

abstract：:Oncocytic phaeochromocytomas are exceedingly rare tumours. To date, there are three reported cases in the literature. This report describes a case of adrenal oncocytic phaeochromocytoma with unique features and malignant potential in a 68-year-old man. The patient presented with an incidental non-functional mass disco...

journal_title：Endocrine pathology

authors： Kasem K,Lam AK

更新日期：2014-12-01 00:00:00

abstract：:Pleomorphic leiomyosarcoma (PLMS) of the adrenal gland is a rare tumor in an unusual location. A primary PLMS of the left adrenal gland is reported in a 59-yr-old Mexican woman who presented progressive flank pain and weight loss. The tumor measured 16 cm in diameter, showed markedly pleomorphic and osteoclast-like gi...

journal_title：Endocrine pathology

authors： Candanedo-González FA,Vela Chávez T,Cérbulo-Vázquez A

更新日期：2005-04-01 00:00:00

abstract：:Solitary fibrous tumor was initially thought to be a pleura-based tumor. However, over the last two decades, its involvement in a variety of extrapleural sites gained recognition. Nonetheless, a primary involvement of the endocrine organs is rare, and in this report, we detail an instance where the tumor affected the ...

journal_title：Endocrine pathology

authors： Ho YH,Yap WM,Chuah KL

更新日期：2010-06-01 00:00:00

abstract：:Twenty-four acromegalic patients were treated with octreotide subcutaneously for periods of 3 to 6 weeks (group I, 12 cases) or 6 months (group II, 12 cases) before transsphenoidal surgery. Radiological studies performed in 19 patients before and at the end of this treatment period revealed no changes in 8 cases. In 8...

journal_title：Endocrine pathology

authors： Beckers A,Kovacs K,Horvath E,Abs R,Reznik M,Stevenaert A

更新日期：1991-09-01 00:00:00

abstract：:The diagnosis of follicular-patterned carcinomas, including follicular thyroid carcinoma, oncocytic (Hürthle cell) carcinoma, and the encapsulated follicular variant of papillary thyroid carcinoma, requires evidence of capsular and/or vascular invasion. With minimally invasive carcinomas classified often within less t...

journal_title：Endocrine pathology

authors： Glomski K,Nosé V,Faquin WC,Sadow PM

更新日期：2017-06-01 00:00:00

abstract：:The presence, distribution, and morphological appearance of S-100 protein-immunoreactive cells in the human hypophysis were studied by immunocytochemistry. One hundred and twelve nonadenomatous pituitaries from fetuses to adults and pituitaries affected by several lesions including metastases, acute infarcts, and lymp...

journal_title：Endocrine pathology

authors： Marin F,Kovacs K,Stefaneanu L,Horvath E,Cheng Z

更新日期：1992-03-01 00:00:00

abstract：:Activating mutations of GNAq protein in a hotspot at codon 209 have been recently described in uveal melanomas. Since these neoplasms share with thyroid carcinomas a high frequency of MAP kinase pathway-activating mutations, we hypothesized whether GNAq mutations could also play a role in the development of thyroid ca...

journal_title：Endocrine pathology

authors： Cassol CA,Guo M,Ezzat S,Asa SL

更新日期：2010-12-01 00:00:00

abstract：:Thyroperoxidase (TPO) is a thyroid-specific enzyme expressed by differentiated thyroid cells. Initial immunohistochemical studies claimed that TPO expression, detected by the monoclonal antibody mAb 47, may be a potentially important diagnostic tool in differentiating malignant from benign lesions. However, some recen...

journal_title：Endocrine pathology

authors： Savin S,Cvejic D,Isic T,Petrovic I,Paunovic I,Tatic S,Havelka M

更新日期：2006-04-01 00:00:00

abstract：:The recent increase in the detection of papillary thyroid carcinoma (PTC) has been influenced by the finding of incidental tumours. To this group, carcinomas measuring less than 1 cm (the so-called microcarcinomas) as well as those above 1 cm belong. Analyzing a case series from our own experience, this paper focuses ...

journal_title：Endocrine pathology

authors： Pagni F,Jaconi M,Delitala A,Garancini M,Maternini M,Bono F,Giani A,Smith A,San Gerardo Hospital collaborators group.

更新日期：2014-09-01 00:00:00

abstract：:The adrenal gland is the body's primary source for epinephrine production and release, and the chromaffin cells that comprise the adrenal medulla possess all of the catecholamine biosynthetic machinery, including phenylethanolamine N-methyltransferase (PNMT), the enzyme synthesizing epinephrine from norepinephrine. In...

journal_title：Endocrine pathology

authors： Wong DL

更新日期：2003-04-01 00:00:00

abstract：:Thyroid pathology encompasses a heterogenous group of clinicopathological entities including rare and diagnostically challenging neoplasms. The review is focused on morphological, immunohistochemical, and molecular features of rare thyroid neoplasms that can pose diagnostic problems. The tumors are organized based on ...

journal_title：Endocrine pathology

authors： Cameselle-Teijeiro JM,Eloy C,Sobrinho-Simões M

更新日期：2020-09-01 00:00:00

abstract：:The history of pituitary pathology is a long one that dates back to biblical times, but the last 25 years have represented an era of "coming of age." The role of the pituitary in health and disease was the subject of many studies over the last century. With the development of electron microscopy, immunoassays, and imm...

journal_title：Endocrine pathology

authors： Asa SL,Mete O

更新日期：2014-03-01 00:00:00

abstract：:Solitary metastasis from prostate adenocarcinoma to thyroid gland is very rare and usually associated with other distal metastasis. This report describes for the first time isolated multiple bilateral thyroid metastasis from prostatic adenocarcinoma. A 67-year-old man who is known as a case of prostatic adenocarcinoma...

journal_title：Endocrine pathology

authors： Albsoul NM,Obeidat FN,Hadidy AM,Alzoubi MN,Taib AA,Shahait AD

更新日期：2013-03-01 00:00:00

abstract：:The histological pattern and the cell proliferative activity (as detected by Ki-67 immunostaining) of a series of 50 parathyroid hyperplasias (PTHs) secondary to renal failure were studied to assess their value in predicting recurrence of hyperparathyrodism (HPT). On account of their clinical evolution, these cases we...

journal_title：Endocrine pathology

authors： Abbona G,Papotti M,Gasparri G,Bussolati G

更新日期：1996-04-01 00:00:00