Primary aldosteronism with aldosterone-producing adenoma consisting of pure zona glomerulosa-type cells in a pregnant woman.

abstract：:Hypophysitis is an inflammatory disease of the pituitary gland that clinically and radiologically mimics pituitary tumors. We report here a case of xanthogranulomatous hypophysitis mimicking a pituitary neoplasm.A 65-yr-old woman presented with weight loss, fatigue, and visual disturbance. Computed tomography demonstr...

journal_title：Endocrine pathology

authors： Yokoyama S,Sano T,Tajitsu K,Kusumoto K

更新日期：2004-01-01 00:00:00

abstract：:The association between papillary thyroid carcinoma (PTC) and Hashimoto's thyroiditis (HT) is controversial. In this study, we aimed to compare preoperative thyroid functions, ultrasonography (US) features, fine-needle aspiration biopsy (FNAB) results, and histopathological characteristics of PTC in patients with and ...

journal_title：Endocrine pathology

authors： Baser H,Ozdemir D,Cuhaci N,Aydin C,Ersoy R,Kilicarslan A,Cakir B

更新日期：2015-12-01 00:00:00

abstract：:Congenital hyperinsulinism is clinically characterized by an inappropriate insulin secretion resulting in recurrent severe hypoglycemia. Nesidioblastosis, the proliferation of islets cells budding off from pancreatic ducts, has been considered for years as the histological lesion responsible for the syndrome. In our m...

journal_title：Endocrine pathology

authors： Sempoux C,Guiot Y,Jaubert F,Rahier J

更新日期：2004-10-01 00:00:00

abstract：:Non-coding (nc)RNAs are divided into small ncRNAs and long ncRNAs (lncRNAs). MicroRNAs (miRNAs) are small ncRNAS which are around 22 nucleotides in length that mediate post-transcriptional gene silencing. LncRNAs are greater than 200 bp in length. Each ncRNA can have multiple targets and can be regulated by multiple g...

journal_title：Endocrine pathology

authors： Zhang R,Hardin H,Chen J,Guo Z,Lloyd RV

更新日期：2016-03-01 00:00:00

abstract：:Although most papillary thyroid carcinomas behave as low-grade neoplasms and are generally associated with a good prognosis, some subgroups of these neoplasms represent more aggressive variants. In order to determine if differences in the behavior of these papillary carcinomas were related to expression of growth fact...

journal_title：Endocrine pathology

authors： Lloyd RV,Ferreiro JA,Jin L,Sebo TJ

更新日期：1997-01-01 00:00:00

abstract：:Twelve surgical specimens of adrenal tumors (3 mainly compact cell adenomas and 2 mainly spongiocytic adenomas of Cushing's syndrome, 4 adenomas of Conn's syndrome, 1 androgen-secreting adenoma, and 2 hormonally inactive tumors) were studied by ultrastructural morphometry, using the point-counting method. All groups w...

journal_title：Endocrine pathology

authors： Saeger W,Saager G,Schubert B,Caselitz J

更新日期：1991-03-01 00:00:00

abstract：:An adenoma resected from a 49-yr-old woman was clinically nonfunctioning but immunopositive for adrenocorticotropic hormone (ACTH) in a few cells. Electron microscopy demonstrated a vacuolar change in Golgi complexes known as "honeycomb Golgi." Recurrent adenoma resected 11 mo later was positive for ACTH in more cells...

journal_title：Endocrine pathology

authors： Sano T,Kovacs K,Asa SL,Yamada S,Sanno N,Yokoyama S,Takami H

更新日期：2002-07-01 00:00:00

abstract：:A case of pancreatic acinar cell tumor (ACC) is presented in a 10-year-old boy. The tumor manifested clinically with Cushing's syndrome, high serum adrenocorticotropic hormone (ACTH) and cortisol concentrations. In addition, excessive serum levels of alpha-fetoprotein (AFP) were detected. Surgical resection was not po...

journal_title：Endocrine pathology

authors： Illyés G,Luczay A,Benyó G,Kálmán A,Borka K,Köves K,Rácz K,Tulassay T,Schaff Z

更新日期：2007-07-01 00:00:00

abstract：:Deregulation of the Wnt pathway has been implicated in oncogenesis of numerous tissues including the pituitary gland. Immunohistochemical localization and quantification of β-catenin, Cyclin D1, c-MYC and Survivin expression in 47 pituitary adenomas (35 non-functioning, seven GH-secreting, three prolactinomas, two ACT...

journal_title：Endocrine pathology

authors： Formosa R,Gruppetta M,Falzon S,Santillo G,DeGaetano J,Xuereb-Anastasi A,Vassallo J

更新日期：2012-06-01 00:00:00

abstract：:Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein highly expressed in fetal tissue and malignant tumors but rarely found in adult benign tissues. In various tumors, IMP3 expression is correlated with increased tumor aggressiveness and reduced overall survival. To our knowledge, IMP3 e...

journal_title：Endocrine pathology

authors： Righi A,Zhang S,Jin L,Scheithauer BW,Kovacs K,Kovacs G,Goth MI,Korbonits M,Lloyd RV

更新日期：2010-03-01 00:00:00

abstract：:Hyperparathyroidism is caused mainly by three different conditions: namely, secondary hyperplasia, primary hyperplasia, and adenoma with only a few cases due to carcinomas. Histological distinction among these diseases is still difficult. In an attempt to characterize the three conditions, 17 cases from patients with ...

journal_title：Endocrine pathology

authors： Shan L,Iwasaki A,Utsunomiya H,Kawano I,Matsuura N,Kobayashi A,Kuma K,Kakudo K

更新日期：1995-07-01 00:00:00

abstract：:Somatostatin type 2A receptor (sstr2A) has been shown to be directly involved in the transduction of antiproliferative effects and also to be the most predominant sstr subtype in human normal breast epithelium, as well as in human breast carcinoma. We investigated the immunoreactivity of sstr2A in 34 cases of human br...

journal_title：Endocrine pathology

authors： Pilichowska M,Kimura N,Schindler M,Suzuki A,Yoshida R,Nagura H

更新日期：2000-04-01 00:00:00

abstract：:Crohn's disease is one of the causes of secondary amyloidosis, which can lead to amyloid infiltration of the thyroid gland. It is essential to follow strict controls to prevent the appearance of a large amyloid goiter. Two patients with amyloid goiter secondary to Crohn's disease, with a large adipose tissue component...

journal_title：Endocrine pathology

authors： Febrero B,Ríos A,Rodríguez JM,Ferri B,Polo L,Parrilla P

更新日期：2012-12-01 00:00:00

abstract：:Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Some PTCs with classical papillae can be totally or partially encapsulated, and these tumors are called "encapsulated" (conventional) variant of papillary thyroid carcinoma. We aimed to investigate the clinicopathological features of this...

journal_title：Endocrine pathology

authors： Akbulut D,Kuz ED,Kursun N,Dizbay Sak S

更新日期：2021-01-04 00:00:00

abstract：:The objective of this study was to evaluate the risk of malignancy (ROM) associated with atypia of undetermined significance (AUS) and suspicious follicular neoplasm (SFN) core needle biopsy (CNB) categories after further sub-classification. Data from 2267 thyroid nodules evaluated by ultrasound-guided CNB, from Janua...

journal_title：Endocrine pathology

authors： Chung SR,Baek JH,Lee JH,Lee YM,Sung TY,Chung KW,Hong SJ,Jeon MJ,Kim TY,Shong YK,Kim WB,Kim WG,Song DE

更新日期：2019-06-01 00:00:00

abstract：:Alterations of the von Hippel-Lindau (VHL) gene, which is supposed to act as a tumor suppressor gene, can cause hereditary tumors associated with the VHL syndrome and are found in different sporadic cancers as well. While VHL protein is distinctly detectable in thyroid follicles, so far its expression in nonneoplastic...

journal_title：Endocrine pathology

authors： Hinze R,Boltze C,Meye A,Holzhausen HJ,Dralle H,Rath FW

更新日期：2000-07-01 00:00:00

abstract：:Collision tumors of the sella turcica are rare and consist mainly of more than one type of pituitary adenoma, usually a corticotropin- and a prolactin-producing adenoma. The association of a craniopharyngioma and a pituitary adenoma is rare. Herein, we report the first case of an association between craniopharyngioma ...

journal_title：Endocrine pathology

authors： Moshkin O,Scheithauer BW,Syro LV,Velasquez A,Horvath E,Kovacs K

更新日期：2009-04-01 00:00:00

abstract：:A 41-yr-old patient with a history of von Hippel-Lindau (VHL) disease with previously removed bilateral pheochromocytomas and renal cell carcinoma presented with progressive obstructive jaundice due to multiple lesions in the pancreas. The pancreatectomy specimen showed a range of endocrine lesions including islet hyp...

journal_title：Endocrine pathology

authors： Chetty R,Kennedy M,Ezzat S,Asa SL

更新日期：2004-07-01 00:00:00

abstract：:Chronic lymphocytic thyroiditis (CLT) has an epidemiological relationship to papillary thyroid carcinoma (PTC). The follicular epithelium in CLT can be markedly atypical, with cytologic changes ranging from oncocytic morphology to clearing and overlapping. At the molecular level, the association between CLT and PTC is...

journal_title：Endocrine pathology

authors： Sargent R,LiVolsi V,Murphy J,Mantha G,Hunt JL

更新日期：2006-10-01 00:00:00

abstract：:We describe a consistently present, previously unrecognized, population of monocytes in pheochromocytomas and paragangliomas. Although sustentacular cells are generally recognized as a common component of these tumors, differential immunohistochemical staining for CD163 and S100 shows that monocytes can in fact be mor...

journal_title：Endocrine pathology

authors： Farhat NA,Powers JF,Shepard-Barry A,Dahia P,Pacak K,Tischler AS

更新日期：2019-06-01 00:00:00

abstract：:Though most paragangliomas arise as sporadic tumors, the recent advantages in the genetic screening revealed that about 30 % of paragangliomas are linked to hereditary mutations, such as those involving SDH genes. A 22-year-old woman carrying a left main bronchus tumor underwent surgery in our institution. Her past me...

journal_title：Endocrine pathology

authors： Ghigna MR,Dorfmuller P,Crutu A,Fadel E,de Montpréville VT

更新日期：2016-12-01 00:00:00

abstract：:In order to characterize the pattern of expression of carbohydrate structures in several types of thyroid tissues and to evaluate the putative usefulness of the detection of such antigens in diagnostic surgical pathology, we undertook the immunohistochemical study of simple mucin type antigens (T, Tn, and sialyl Tn), ...

journal_title：Endocrine pathology

authors： Fonseca E,Castanhas S,Sobrinho-Simoes M

更新日期：1996-01-01 00:00:00

abstract：:A cell fine of human medullary carcinoma of the thyroid, abundantly producing calcitonin (Ct) and related hormones, has proved remarkably useful as an endocrine tumor model for the study of the secretion mechanism. This cell line (TT cell) was used in studies to elucidate the dynamics of the release of Ct and chromogr...

journal_title：Endocrine pathology

authors： Kameya T,Kadoya K,Iguchi H,Abe Y,Shimaoka K

更新日期：1991-03-01 00:00:00

abstract：:The recent increase in the detection of papillary thyroid carcinoma (PTC) has been influenced by the finding of incidental tumours. To this group, carcinomas measuring less than 1 cm (the so-called microcarcinomas) as well as those above 1 cm belong. Analyzing a case series from our own experience, this paper focuses ...

journal_title：Endocrine pathology

authors： Pagni F,Jaconi M,Delitala A,Garancini M,Maternini M,Bono F,Giani A,Smith A,San Gerardo Hospital collaborators group.

更新日期：2014-09-01 00:00:00

abstract：:This study compared the expression profile of HBME-1 and claudin-1 in 90 papillary thyroid carcinomas (PTCs) with respect to the tumor architecture and invasive growth as reflected in 46 BRAF-like, 31 non-invasive RAS, and 13 invasive RAS-like phenotypes. Individual tumors were given an expression score (max 300) by m...

journal_title：Endocrine pathology

authors： Gucer H,Bagci P,Bedir R,Sehitoglu I,Mete O

更新日期：2016-09-01 00:00:00

abstract：:C cell hyperplasia is considered a precursor lesion for hereditary forms of medullary thyroid carcinoma. It has therefore been suggested as a morphological marker to distinguish hereditary from sporadic medullary thyroid carcinoma and to triage genetic testing in resource poor settings. However, numerous definitions f...

journal_title：Endocrine pathology

authors： Fuchs TL,Bell SE,Chou A,Gill AJ

更新日期：2019-06-01 00:00:00

abstract：:The incidence and histology of cysts in the adenohypophysis of adult male Wistar rats are reported. Of sixty pituitaries studied 13 of them (21.6%) presented a single cyst located in the pars distalis. The cysts varied in shape and size and were usually multilocular. Two of them were connected with the subdural space ...

journal_title：Endocrine pathology

authors： Quintanar-Stephano A,Muñoz Fernández L,Quintanar JL,Kovacs K

更新日期：2001-04-01 00:00:00

abstract：:The histological pattern and the cell proliferative activity (as detected by Ki-67 immunostaining) of a series of 50 parathyroid hyperplasias (PTHs) secondary to renal failure were studied to assess their value in predicting recurrence of hyperparathyrodism (HPT). On account of their clinical evolution, these cases we...

journal_title：Endocrine pathology

authors： Abbona G,Papotti M,Gasparri G,Bussolati G

更新日期：1996-04-01 00:00:00

abstract：:The expression of programmed death-ligand 1 (PD-L1) is an established prerequisite for the administration of checkpoint inhibitor therapy and is of prognostic value in several cancer types. Data concerning the potential effect of PD-L1 on the prognosis of thyroid carcinoma are limited. Therefore, this study aimed to p...

journal_title：Endocrine pathology

authors： Girolami I,Pantanowitz L,Mete O,Brunelli M,Marletta S,Colato C,Trimboli P,Crescenzi A,Bongiovanni M,Barbareschi M,Eccher A

更新日期：2020-09-01 00:00:00

abstract：:Hyalinizing trabecular tumor (HTT) is a rare thyroid tumor of follicular cell origin with a trabecular pattern of growth and marked intratrabecular hyalinization. This tumor is known to share morphological and architectural similarities with paraganglioma and medullary thyroid carcinoma, as well as the nuclear feature...

journal_title：Endocrine pathology

authors： Nosé V,Volante M,Papotti M

更新日期：2008-04-01 00:00:00