Abstract:
:The cardiac and skeletal muscle isoforms of calsequestrin (CS), the low affinity, high capacity Ca2+ binding protein localized in the lumen of sarcoplasmic reticulum, are the products of two different genes (Fliegel, L., Leberer, E., Green, N.M. and MacLennan, D.H. (1982) FEBS Lett. 242, 297-300), and can be both purified from slow-twitch skeletal muscle of the rabbit (Damiani, E., Volpe, P. and Margreth, A. (1990) J. Muscle Res. Cell Motil. 11, 522-530). Here we show that both CS isoforms coexist in slow-twitch muscle fibers as indicated by indirect immunofluorescent staining of cryosections with affinity-purified antibodies specific for each CS isoform.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Biral D,Volpe P,Damiani E,Margreth Adoi
10.1016/0014-5793(92)80241-8keywords:
subject
Has Abstractpub_date
1992-03-09 00:00:00pages
175-8issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(92)80241-8journal_volume
299pub_type
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