Abstract:
:The two subunits of gamma-glutamyl transpeptidase (EC 2.3.2.2) are derived from a single-chain glycosylated precursor. A small fraction of the propeptide survives proteolytic processing in the rat kidney and has been purified by an immunoaffinity technique. The propeptide contains determinants for both the subunits and its amino acid composition resembles that of the dimeric enzyme. However, the propeptide exhibits less than 2% of the transpeptidase activity shown by the dimeric enzyme.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Tate SSdoi
10.1016/0014-5793(86)80046-1subject
Has Abstractpub_date
1986-01-01 00:00:00pages
33-8issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(86)80046-1journal_volume
194pub_type
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