Variable female preferences drive complex male displays.

abstract：:The basolateral amygdala (BLA) has a crucial role in emotional learning irrespective of valence. The BLA projection to the nucleus accumbens (NAc) is thought to modulate cue-triggered motivated behaviours, but our understanding of the interaction between these two brain regions has been limited by the inability to man...

journal_title：Nature

authors： Stuber GD,Sparta DR,Stamatakis AM,van Leeuwen WA,Hardjoprajitno JE,Cho S,Tye KM,Kempadoo KA,Zhang F,Deisseroth K,Bonci A

更新日期：2011-06-29 00:00:00

abstract：:The 2.2 A crystal structure of activated rod transducin, Gt alpha.GTP gamma S, shows the bound GTP gamma S molecule occluded deep in a cleft between a domain structurally homologous to small GTPases and a helical domain unique to heterotrimeric G proteins. The structure, when combined with biochemical and genetic stud...

journal_title：Nature

authors： Noel JP,Hamm HE,Sigler PB

更新日期：1993-12-16 00:00:00

abstract：:In fission yeast, meiosis is initiated by transcriptional activation of the mei3+ gene, under the combined influence of the four mating-type genes. The product of the mei3+ gene acts as a critical meiotic inducer by binding non-covalently to a newly identified protein kinase encoded by the ran1+ gene and inhibiting it...

journal_title：Nature

authors： McLeod M,Beach D

更新日期：1988-04-07 00:00:00

abstract：:The complexity of ecosystems can cause subtle and chaotic responses to changes in external forcing. Although ecosystems may not normally behave chaotically, sensitivity to external influences associated with nonlinearity can lead to amplification of climatic signals. Strong correlations between an El Niño index and ra...

journal_title：Nature

authors： Taylor AH,Allen JI,Clark PA

更新日期：2002-04-11 00:00:00

abstract：:Excitatory amino acids induce both acute membrane depolarization and latent cellular toxicity, which often leads to apoptosis in many neurological disorders. Recent studies indicate that glutamate toxicity may involve the c-Jun amino-terminal kinase (JNK) group of mitogen-activated protein (MAP) kinases. One member of...

journal_title：Nature

authors： Yang DD,Kuan CY,Whitmarsh AJ,Rincón M,Zheng TS,Davis RJ,Rakic P,Flavell RA

更新日期：1997-10-23 00:00:00

abstract：:The evolution of snakes involved major changes in vertebrate body plan organization, but the developmental basis of those changes is unknown. The python axial skeleton consists of hundreds of similar vertebrae, forelimbs are absent and hindlimbs are severely reduced. Combined limb loss and trunk elongation is found in...

journal_title：Nature

authors： Cohn MJ,Tickle C

更新日期：1999-06-03 00:00:00

abstract：:Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality. Studies of rare human disorders of puberty and animal models point to a compl...

journal_title：Nature

authors： Perry JR,Day F,Elks CE,Sulem P,Thompson DJ,Ferreira T,He C,Chasman DI,Esko T,Thorleifsson G,Albrecht E,Ang WQ,Corre T,Cousminer DL,Feenstra B,Franceschini N,Ganna A,Johnson AD,Kjellqvist S,Lunetta KL,McMahon G,N

更新日期：2014-10-02 00:00:00

abstract：:Jets of highly energized plasma with relativistic velocities are associated with black holes ranging in mass from a few times that of the Sun to the billion-solar-mass black holes at the centres of galaxies. A popular but unconfirmed hypothesis to explain how the plasma is energized is the 'internal shock model', in w...

journal_title：Nature

authors： Meyer ET,Georganopoulos M,Sparks WB,Perlman E,van der Marel RP,Anderson J,Sohn ST,Biretta J,Norman C,Chiaberge M

更新日期：2015-05-28 00:00:00

abstract：:Innate immune responses are important in combating various microbes during the early phases of infection. Natural killer (NK) cells are innate lymphocytes that, unlike T and B lymphocytes, do not express antigen receptors but rapidly exhibit cytotoxic activities against virus-infected cells and produce various cytokin...

journal_title：Nature

authors： Moro K,Yamada T,Tanabe M,Takeuchi T,Ikawa T,Kawamoto H,Furusawa J,Ohtani M,Fujii H,Koyasu S

更新日期：2010-01-28 00:00:00

abstract：:Phelan-McDermid syndrome (PMDS) is a complex neurodevelopmental disorder characterized by global developmental delay, severely impaired speech, intellectual disability, and an increased risk of autism spectrum disorders (ASDs). PMDS is caused by heterozygous deletions of chromosome 22q13.3. Among the genes in the dele...

journal_title：Nature

authors： Shcheglovitov A,Shcheglovitova O,Yazawa M,Portmann T,Shu R,Sebastiano V,Krawisz A,Froehlich W,Bernstein JA,Hallmayer JF,Dolmetsch RE

更新日期：2013-11-14 00:00:00

abstract：:Mammal-like reptiles of the order Therapsida document the emergence of mammals from more primitive synapsids and are of unique zoological and palaeontological interest on that account. Therapsids, first appearing in the Early Permian, were thought to become extinct in the Middle Jurassic, soon after the Late Triassic ...

journal_title：Nature

authors： Fox RC,Youzwyshyn GP,Krause DW

更新日期：1992-07-16 00:00:00

abstract：:In information processing, as in physics, our classical world view provides an incomplete approximation to an underlying quantum reality. Quantum effects like interference and entanglement play no direct role in conventional information processing, but they can--in principle now, but probably eventually in practice--b...

journal_title：Nature

authors： Bennett CH,DiVincenzo DP

更新日期：2000-03-16 00:00:00

abstract：:Combined analyses of gene networks and DNA sequence variation can provide new insights into the aetiology of common diseases that may not be apparent from genome-wide association studies alone. Recent advances in rat genomics are facilitating systems-genetics approaches. Here we report the use of integrated genome-wid...

journal_title：Nature

authors： Heinig M,Petretto E,Wallace C,Bottolo L,Rotival M,Lu H,Li Y,Sarwar R,Langley SR,Bauerfeind A,Hummel O,Lee YA,Paskas S,Rintisch C,Saar K,Cooper J,Buchan R,Gray EE,Cyster JG,Cardiogenics Consortium.,Erdmann J,Heng

更新日期：2010-09-23 00:00:00

abstract：:The flow of terrestrial groundwater to the sea is an important natural component of the hydrological cycle. This process, however, does not explain the large volumes of low-salinity groundwater that are found below continental shelves. There is mounting evidence for the global occurrence of offshore fresh and brackish...

journal_title：Nature

authors： Post VE,Groen J,Kooi H,Person M,Ge S,Edmunds WM

更新日期：2013-12-05 00:00:00

abstract：:Mutation of the XRCC4 gene in mammalian cells prevents the formation of the signal and coding joints in the V(D)J recombination reaction, which is necessary for production of a functional immunoglobulin gene, and renders the cells highly sensitive to ionizing radiation. However, XRCC4 shares no sequence homology with ...

journal_title：Nature

authors： Grawunder U,Wilm M,Wu X,Kulesza P,Wilson TE,Mann M,Lieber MR

更新日期：1997-07-31 00:00:00

abstract：:Following the introduction of hydrochlorofluorocarbon (HCFCs) and hydrofluorocarbon (HFCs) gases as replacements for the ozone-destroying chlorofluorocarbons (CFCs), it has been discovered that HCFCs/HFCs can degrade in the atmosphere to produce trifluoroacetic acid, a compound with no known loss mechanisms in the env...

journal_title：Nature

authors： Ellis DA,Mabury SA,Martin JW,Muir DC

更新日期：2001-07-19 00:00:00

abstract：:All synaptically-based neuropsychological theories of learning postulate that there are changes resulting from neural activity which are long-lasting and confined to specific sets of synapses. In the past decade a form of synaptic strengthening known as long-term potentiation (LTP) has been found which results from hi...

journal_title：Nature

authors： Abraham WC,Goddard GV

更新日期：1983-10-20 00:00:00

abstract：:Transcription initiation factor TFIID is a multisubunit complex containing a TATA-box-binding factor (TFIID tau/TBP) and associated polypeptide factors (TAFs) with sizes ranging from M(r) approximately 20,000 to > 200,000. As a result of direct promoter interactions, TFIID nucleates the assembly of RNA polymerase II a...

journal_title：Nature

authors： Kokubo T,Gong DW,Wootton JC,Horikoshi M,Roeder RG,Nakatani Y

更新日期：1994-02-03 00:00:00

abstract：:There is compelling evidence that sleep contributes to the long-term consolidation of new memories. This function of sleep has been linked to slow (<1 Hz) potential oscillations, which predominantly arise from the prefrontal neocortex and characterize slow wave sleep. However, oscillations in brain potentials are comm...

journal_title：Nature

authors： Marshall L,Helgadóttir H,Mölle M,Born J

更新日期：2006-11-30 00:00:00

abstract：:Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery and annotation are pre-requisites for understanding how the regulation of transcription, splicing and...

journal_title：Nature

authors： Graveley BR,Brooks AN,Carlson JW,Duff MO,Landolin JM,Yang L,Artieri CG,van Baren MJ,Boley N,Booth BW,Brown JB,Cherbas L,Davis CA,Dobin A,Li R,Lin W,Malone JH,Mattiuzzo NR,Miller D,Sturgill D,Tuch BB,Zaleski C,

更新日期：2011-03-24 00:00:00

abstract：:Introduced in its contemporary form in 1946 (ref. 1), but with roots that go back to the eighteenth century, the gravity law is the prevailing framework with which to predict population movement, cargo shipping volume and inter-city phone calls, as well as bilateral trade flows between nations. Despite its widespread ...

journal_title：Nature

authors： Simini F,González MC,Maritan A,Barabási AL

更新日期：2012-02-26 00:00:00

abstract：:The antigen receptors on mature B lymphocytes are membrane-bound immunoglobulins of the IgM and IgD classes whose cross-linking by polyvalent antigens results in B-cell proliferation and differentiation. How these membrane-bound immunoglobulin chains, which lack a cytoplasmic tail, generate a cell activation signal is...

journal_title：Nature

authors： Hombach J,Tsubata T,Leclercq L,Stappert H,Reth M

更新日期：1990-02-22 00:00:00

abstract：: ...

journal_title：Nature

authors： Chiao M

更新日期：2018-11-01 00:00:00

abstract：:The high-resolution seismic imaging of subducted oceanic slabs has become a powerful tool for reconstructing palaeogeography. The images can now be interpreted quantitatively by comparison with models of the general circulation of the Earth's mantle. Here we use a three-dimensional spherical computer model of mantle c...

journal_title：Nature

authors： Bunge HP,Grand SP

更新日期：2000-05-18 00:00:00

abstract：:Ionic currents from individual K+ channels in squid axon membrane have been recorded. At hyperpolarizing membrane voltages, unit events occur as widely spaced rectangular pulses with short interruptions. The frequency of occurrence of the units increases strongly when the membrane is depolarized. ...

journal_title：Nature

authors： Conti F,Neher E

更新日期：1980-05-15 00:00:00

abstract：:Intracellular responses recorded in vitro from the cochleas of anaesthetized mammals have shown that the mechanoreceptive inner and outer hair cells are sharply tuned, accounting for many of the properties of the afferent fibres in the auditory nerve. However, in vivo it has not been possible to measure directly the e...

journal_title：Nature

authors： Russell IJ,Richardson GP,Cody AR

更新日期：1986-05-29 00:00:00

abstract：:Stimulation of transient increases in intracellular calcium (Cai2+) activates protein kinases, regulates transcription and influences motility and morphology. Developing neurons generate spontaneous Cai2+ transients, but their role in directing neuronal differentiation and the way in which they encode information are ...

journal_title：Nature

authors： Gu X,Spitzer NC

更新日期：1995-06-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature

authors： Grishin E,Malamud U,Perets HB,Wandel O,Schäfer CM

更新日期：2020-06-01 00:00:00

abstract：:Growing concern about how loss of biodiversity will affect ecosystems has stimulated numerous studies. Although most studies have assumed that species go extinct randomly, species often go extinct in order of their sensitivity to a stress that intensifies through time (such as climate change). Here we show that the co...

journal_title：Nature

authors： Ives AR,Cardinale BJ

更新日期：2004-05-13 00:00:00

abstract：:The terrestrial sediment record indicates that the Earth's climate varied drastically in the Precambrian era (before 550 million years ago), ranging from surface temperatures similar to or higher than today's to global glaciation events. The most continuous record of sea surface temperatures of that time has been deri...

journal_title：Nature

authors： Robert F,Chaussidon M

更新日期：2006-10-26 00:00:00