Abstract:
:Properties of Klebsiella pneumoniae respiratory chain enzymes catalyzing NADH oxidation have been studied. Using constructed K. pneumoniae mutant strains, it was shown that three enzymes belonging to different families of NADH:quinone oxidoreductases operate in this bacterium. The NDH-2-type enzyme is not coupled with energy conservation, the NDH-1-type enzyme is a primary proton pump, and the NQR-type enzyme is homologous to the sodium-motive NADH dehydrogenase of Vibrio and is shown to be a primary Na(+) pump. It is concluded that the NQR-type enzyme, not the NDH-1-type enzyme, catalyzes sodium-dependent NADH oxidation in K. pneumoniae.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Bertsova YV,Bogachev AVdoi
10.1016/S0014-5793(04)00312-6keywords:
subject
Has Abstractpub_date
2004-04-09 00:00:00pages
207-12issue
1-3eissn
0014-5793issn
1873-3468pii
S0014579304003126journal_volume
563pub_type
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