Abstract:
:A 21-year-old male developed back pain, fever, and rapidly progressive quadriparesis. Lumbar tap yielded frank pus which was confirmed on magnetic resonance imaging (MRI) to be located mainly in the cervical epidural space. Conservative antibiotic remedy was partially effective for restoration of the neurological deficits. A 82-year-old female noticed low-back pain which was rapidly accompanied with clouding of consciousness, paraplegia, and sphincter disturbances. Lumbar puncture revealed thick pus which was best depicted on MRI in the thoracolumbar subarachnoid space. At autopsy, spinal subarachnoid abscess or leptomeningitis was confirmed, and a spinal infarction previously unrecognized on MRI was found. Usefulness and shortcomings of MRI in the diagnosis of paraspinal infections are discussed.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Fukui T,Ichikawa H,Kawate N,Nozawa T,Sugita Kdoi
10.1159/000116855keywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
328-33issue
6eissn
0014-3022issn
1421-9913journal_volume
32pub_type
杂志文章abstract::Cavernomas are vascular malformations mostly observed in the central nervous system. They occur in sporadic and familial forms. Familial forms are characterized by the presence of multiple lesions, an autosomal dominant pattern of inheritance and possible de novo lesions. We report two sporadic cases whose follow-up s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000052100
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the influence of psychosocial variables on patients with multiple sclerosis (MS) and the relationship between these variables and the onset of MS. BACKGROUND:The current evidence indicates that many types of psychosocial factors are involved in the development and rel...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000226428
更新日期:2009-01-01 00:00:00
abstract::L-Dopa pioneered the symptomatic therapy of Parkinson's disease. While this treatment proved effective in the treatment of parkinsonian akinesia, rigidity and tremor, prolonged L-dopa treatment was often noted to result in dyskinesia, psychosis and 'on-off' phenomena. This increasing disability of L-Dopa-treated parki...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000119537
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in p...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000487717
更新日期:2018-01-01 00:00:00
abstract::The authors present 2 cases in which urinary retention was related to supratentorial cortical lesions. These cases support the presence and function of a supratentorial center involved in control of the voiding reflex loop and indicate that lesions affecting this center can result in urinary retention rather than the ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117199
更新日期:1996-01-01 00:00:00
abstract::The purpose of this study was to evaluate the contribution of the postsynaptic mechanism to the development of motor fluctuation in advanced Parkinson's disease (PD). We used 123I-iodobenzamide single-photon emission computed tomography to measure the striatal dopamine D2 receptor densities in early levodopa-naïve PD,...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000047962
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To study gender differences of coping with illness strategies in tension-type headaches. METHOD:We enrolled 89 subjects (50 women, 39 men) suffering from episodic (n = 37) and chronic (n = 52) tension-type headaches (TTH). Patients were required to answer a Freiburg Questionnaire of Coping with Illness (FQCI...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000072502
更新日期:2003-01-01 00:00:00
abstract::Bilateral choroid plexus papillomas, or villous hypertrophy of the choroid plexus, is a very rare entity that presents serious therapeutical problems in the management of secondary oversecretive hydrocephalus. The authors report the cases of 2 infants affected by this condition, and cured with removal of the lateral v...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117402
更新日期:1997-01-01 00:00:00
abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116350
更新日期:1987-01-01 00:00:00
abstract::The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008008
更新日期:1999-01-01 00:00:00
abstract::About one third of patients with newly diagnosed epilepsy do not achieve seizure control despite medical therapy and should be assessed in detail to confirm the diagnosis, to determine the epilepsy syndrome and to plan treatment strategy. Refractory epilepsy is established when there is inadequate seizure control desp...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000222775
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Statins inhibit the production of 2,3-dimethoxy,5-methyl,6-polyisoprene parabenzoquinone also known as ubiquinone or coenzyme Q10 (CoQ10), which is required for mitochondrial electron transport. Idiopathic or primary CoQ10 deficiencies have been known to cause mitochondrial encephalomyopathy. METHODS:We pre...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000101287
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To determine whether orbitofrontal cortex (OFC) function improves with blepharospasm (BSP) symptom remission using a verbal fluency task and near-infrared spectroscopy (NIRS). METHODS:Nineteen BSP patients and 9 healthy controls (HCs) matched by gender and education were examined using NIRS. The BSP patients...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000471850
更新日期:2017-01-01 00:00:00
abstract::A method is described to relate brain morphology and neuropsychological disturbances such as aphasia. By mapping lesions with computerized tomography onto a grid model of five brain slices, it is possible to compare aphasiological information and lesion site by data processing, allowing the quantitative and qualitativ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115210
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Large cavitary lesions are not typical for multiple sclerosis (MS). Cavitary white matter changes may be seen in megalencephalic leukoencephalopathy with subcortical cysts, Alexander disease, mitochondrial leukoencephalopathies, vanishing white matter disease, leukoencephalopathy with calcifications and cyst...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000338476
更新日期:2012-01-01 00:00:00
abstract::There is good evidence that patients with Parkinson's disease have respiratory chain dysfunction in their substantia nigra. Since mitochondrial cytopathies due to enzyme defects in the respiratory chain are predominantly manifested in tissues with a high oxidative metabolism we analyzed oxidative energy metabolism in ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117053
更新日期:1994-01-01 00:00:00
abstract::40 patients with multiple sclerosis were investigated by magnetic resonance imaging (MRI) and computer tomography (CT). Additionally, cerebrospinal fluid (CSF) findings and evoked potentials (EPs; visual, brainstem) were evaluated. MRI findings were abnormal in 85% of the patients, whilst CT scan showed pathological c...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116269
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND/AIMS:Newer Scandinavian data on intracerebral hemorrhage (ICH) are scarce. We aimed at providing updated community-based data on the incidence, characteristics and outcome of ICH leading to hospitalization in the southernmost region in Norway. METHODS:We analyzed data from all consecutive patients hospitali...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000336299
更新日期:2012-01-01 00:00:00
abstract::The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000075518
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Tuberculous meningitis is the severest and commonest form of central nervous system tuberculosis causing high mortality and morbidity. We aim to study the clinical, biochemical, and radiological characteristics of tuberculous meningitis in adult patients in Qatar and to calculate the incidence. METHODS:A de...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000368894
更新日期:2015-01-01 00:00:00
abstract::The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000197103
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000215876
更新日期:2009-01-01 00:00:00
abstract::We have recently observed a diffuse slowing of brain waves using serial quantitative electroencephalographic (qEEG) examinations in interferon (IFN)-alpha-treated chronic hepatitis C patients. However, it remains unclear how this alteration could be assessed. We evaluated the correlation between the qEEG changes and t...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000062997
更新日期:2002-01-01 00:00:00
abstract:AIM:To determine the association between interleukin-6 (IL-6) and soluble E-selectin (sE-selectin) levels with the electrodiagnostic abnormalities in patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). METHODS:Serum HbA1c, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), f...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000444661
更新日期:2016-01-01 00:00:00
abstract::The purpose of this pilot study was to determine whether 20 mg oral 311C90 can prevent the development of migraine headache when taken during the aura phase of a migraine attack. The study also aimed to provide an initial safety profile for 311C90 when taken during the aura. Forty patients (31 females, 9 males) were e...
journal_title:European neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000119101
更新日期:1996-01-01 00:00:00
abstract::In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116233
更新日期:1988-01-01 00:00:00
abstract::Of 150 new cases of nasopharyngeal carcinoma diagnosed in Israel during a 9-year period (nationwide study 1960--1968), 74 patients developed neurological complications. In 92% of the cases, neurologic deficits were confined exclusively to cranial nerves. The majority of these patients presented general symptoms of dis...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114938
更新日期:1978-01-01 00:00:00
abstract::Heretofore unreported findings in skeletal muscle in a 4th case of pure postganglionic dysautonomia are described. They consist of variation in fiber size, Z line and myofilamentous disorganization, intracytoplasmic inclusions and honeycomb formations. The most striking alterations, however, was excess lipid accumulat...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115448
更新日期:1982-01-01 00:00:00
abstract::A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115736
更新日期:1984-01-01 00:00:00
abstract::The consequences of cerebral infarcts involving the left hemisphere differ from those of the right homologue areas. Data of 337 consecutive, unselected patients with acute ischaemic stroke in the territory of the right or left middle cerebral artery were analysed. Furthermore, lesion locations of 77 stroke patients wi...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000065515
更新日期:2002-01-01 00:00:00