Abstract:
:A method is described to relate brain morphology and neuropsychological disturbances such as aphasia. By mapping lesions with computerized tomography onto a grid model of five brain slices, it is possible to compare aphasiological information and lesion site by data processing, allowing the quantitative and qualitative manipulation of a large number of data. The soundness of the method is investigated in a pilot study on the localization of aphasic disturbances. Data processing was performed on a preliminary group of 70 patients with different aphasic syndromes (Broca, Wernicke, and global aphasics with and without recurring utterances). The results confirmed the findings of older studies, with the typical locus of Wernicke's aphasia being Wernicke's area. In conformity to more recent studies, the main lesion for Broca aphasics was found to be in the insular cortex, with a relatively important participation of the frontal white matter. The implications of this refined method for more vigorous aphasiological and neuropsychological research are briefly indicated.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Blunk R,De Bleser R,Willmes K,Zeumer Hdoi
10.1159/000115210subject
Has Abstractpub_date
1981-01-01 00:00:00pages
69-79issue
2eissn
0014-3022issn
1421-9913journal_volume
20pub_type
杂志文章abstract::Divers may be at risk of long-term CNS damage from non-symptomatic hyperbaric exposure. We investigated the effect of severe, controlled hyperbaric exposure on a group of healthy goats with similar histories. Thirty goats were exposed to various dive profiles over a period of 5 years, with 17 experiencing decompressio...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000079254
更新日期:2004-01-01 00:00:00
abstract::This study investigates the remote effects of botulinum toxin injections by examining the motor unit architecture of noninjected distant muscles. In 21 dystonia patients treated with botulinum toxin (n = 11, mean cumulative dose = 815 mU; n = 10, mean cumulative dose = 7,207 mU) and 10 control individuals, a blinded s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008222
更新日期:2000-01-01 00:00:00
abstract::Of 150 new cases of nasopharyngeal carcinoma diagnosed in Israel during a 9-year period (nationwide study 1960--1968), 74 patients developed neurological complications. In 92% of the cases, neurologic deficits were confined exclusively to cranial nerves. The majority of these patients presented general symptoms of dis...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114938
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Saccade may be abnormal in Parkinson's disease (PD), but there have been no systematic studies on directional asymmetries of horizontal saccades in early PD. The aims of this study were to determine the saccadic abnormalities and their directional asymmetries. METHODS:We recorded visually guided horizontal ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000330671
更新日期:2011-01-01 00:00:00
abstract::Tardive dyskinesia (TD) induced by antipsychotic drugs represents a great concern for patients and psychiatrists. Considering its pathophysiological mechanisms, there exists a convergence towards the development of postsynaptic dopaminergic hypersensitivity as a possible cause of TD. Hypersensitivity following recepto...
journal_title:European neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000116678
更新日期:1991-01-01 00:00:00
abstract::A young man presented with myokymias, cramp-like difficulty in muscle relaxation and peroneal atrophy. EMG studies revealed continuous muscle activity (CMA) manifested as grouped potentials and high frequency discharges. Sensory nerve conduction studies and sural nerve biopsy gave normal results, and he was thought to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116667
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the plasma levels of factor VIII (FVIII), von Willebrand factor (vWF) and their association in patients with cerebral venous sinus thrombosis (CVST). METHODS:We prospectively included 25 CVST patients admitted to the university hospital and 53 voluntary subjects as a cont...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000331048
更新日期:2011-01-01 00:00:00
abstract::This retrospective study aims to assess cognitive involvement in pre-AIDS, not drug abuser subjects and to determine whether CD4 status or disease stage best correlates with cognitive changes that may portend development of ADC. 328 cases were analyzed. No differences in psychometric performance in relation to CDC sta...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008112
更新日期:1999-01-01 00:00:00
abstract::Reduction in caeruloplasmin (Cp) levels is sometimes found in other sporadic movement disorders, not limited to Wilson's disease (WD). Serum levels of Cp, copper, iron and gamma-glutamyl transpeptidase were measured in 71 patients with various diagnoses of movement disorders, including Parkinson's disease (PD), atypic...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000330538
更新日期:2011-01-01 00:00:00
abstract::Nerve conduction of single impulses and the ability to transmit frequent trains of stimuli were studied in sensory median and in sural nerves of controls and patients with diabetes mellitus. Decrease of relative amplitudes and increase of relative latencies were more marked in the diabetics as compared with normal con...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115123
更新日期:1980-01-01 00:00:00
abstract::L-Dopa pioneered the symptomatic therapy of Parkinson's disease. While this treatment proved effective in the treatment of parkinsonian akinesia, rigidity and tremor, prolonged L-dopa treatment was often noted to result in dyskinesia, psychosis and 'on-off' phenomena. This increasing disability of L-Dopa-treated parki...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000119537
更新日期:1994-01-01 00:00:00
abstract::The gradual intraneuronal accumulation of an insoluble fibrous material which partly consists of abnormally phosphorylated tau protein (neurofibrillary change) represents an important neuropathological hallmark of Alzheimer's disease. Neurofibrillary tangles and neuropil threads formed from this material develop in on...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000116984
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease. METHODS:One hundred and thirty-three women with...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000165349
更新日期:2009-01-01 00:00:00
abstract::A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116120
更新日期:1987-01-01 00:00:00
abstract::The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000445540
更新日期:2016-01-01 00:00:00
abstract::The authors present 2 cases in which urinary retention was related to supratentorial cortical lesions. These cases support the presence and function of a supratentorial center involved in control of the voiding reflex loop and indicate that lesions affecting this center can result in urinary retention rather than the ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117199
更新日期:1996-01-01 00:00:00
abstract::Long-term development of psychological deficits in disability-free early multiple sclerosis (MS) was evaluated in 27 female patients over a period of 7 years and compared with healthy controls. Physical and cognitive parameters deteriorated significantly but not depression scores. In particular, the self-assessed soma...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000079937
更新日期:2004-01-01 00:00:00
abstract::2 patients with hypoparathyroidism, one idiopathic and the other pseudoform, were studied by overnight polygraphic recording of the sleep EEG and related activities before and after start of treatment to investigate their sleep EEG patterns and states, with the results as follows. (1) Conspicuous abnormalities were no...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115052
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000479003
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Intravenous thrombolysis (IVT) with urokinase is the standard reperfusion therapy for acute cerebral infarction (ACI) in China. Only about 30% patients who use urokinase for IVT can recanalize. Therefore, this study aimed to analyze the influencing factors of recanalization after IVT using urokinase in ACI p...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000507288
更新日期:2020-01-01 00:00:00
abstract::This study assessed gender differences in diabetic patients with ischemic stroke with respect to vascular risk factors, clinical features and early outcome. Ischemic stroke was diagnosed in 261 diabetic women and 300 diabetic men of 2,446 ischemic stroke patients included in a prospective stroke registry over 17 years...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000094249
更新日期:2006-01-01 00:00:00
abstract::Ten patients with left-sided visuospatial neglect due to cerebrovascular accident were monitored using the Behavioural Inattention Test (BIT) at weekly intervals, on a long-term basis. The novel finding was that some patients showed occasional but transitory marked improvement in their visuospatial neglect at times pr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117028
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in p...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000487717
更新日期:2018-01-01 00:00:00
abstract::Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000113399
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. METHODS:An in-depth ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000503626
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the diagnostic yield of nerve biopsy in patients with peripheral neuropathy of undetermined cause despite extensive diagnostic workup. METHODS:From November 2001 through January 2004, 38 patients underwent nerve biopsy because of unclassified neuropathy. RESULTS:The etiology of the neuropathies...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000098057
更新日期:2007-01-01 00:00:00
abstract::Many gadolinium-enhanced magnetic resonance imaging (MRI) studies focusing on the anatomy and pathology of the 7th cranial nerve have already been published. However, only scattered cases of herpes zoster oticus (HZO) have been described and only the MRI appearance of the soft temporal bone structures has been reporte...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000007900
更新日期:1998-01-01 00:00:00
abstract::Anticonvulsant therapy was stopped in 191 epileptic children (109 males and 82 females) after a seizure-free period of at least 2 years, independent of EEG findings, followed up for a minimum of 2 years after withdrawal. Overall, 43 (22.5%) had recurrence of seizures; of these, 79% relapsed within the 1st year after d...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116811
更新日期:1992-01-01 00:00:00
abstract::Although many studies have been performed on nervous tissue pathology in Guillain-Barré syndrome (GBS), much less is known about pathological changes in skeletal muscle in this disorder. We have studied muscle biopsies from 5 patients with GBS, 5 patients with amyotrophic lateral sclerosis (control A), and 5 patients ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000007924
更新日期:1998-01-01 00:00:00
abstract::This study aimed at examining correlations between quantitative REM sleep EEG, regional cerebral blood flow measured by single photon emission computerized tomography (SPECT) and global cognitive functioning in nine patients with mild to moderate Alzheimer's disease. REM sleep EEG was not correlated with SPECT measure...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000117247
更新日期:1996-01-01 00:00:00