Abstract:
:This study aimed at examining correlations between quantitative REM sleep EEG, regional cerebral blood flow measured by single photon emission computerized tomography (SPECT) and global cognitive functioning in nine patients with mild to moderate Alzheimer's disease. REM sleep EEG was not correlated with SPECT measures in any of the 6 regions studied. However, degrees of interhemispheric asymmetry calculated by both measures were concordant for the parieto-occipital region. Mini-mental state score correlated with REM sleep EEG slowing for left frontal, left and right parieto-occipital and left temporal regions but was not correlated with SPECT measures for any of the six regions. These results suggest that quantitative REM sleep EEG would be more useful than SPECT for evaluating cerebral dysfunctions in mild to moderate Alzheimer's disease.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Montplaisir J,Petit D,McNamara D,Gauthier Sdoi
10.1159/000117247subject
Has Abstractpub_date
1996-01-01 00:00:00pages
197-200issue
4eissn
0014-3022issn
1421-9913journal_volume
36pub_type
临床试验,杂志文章abstract:PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000050752
更新日期:2001-01-01 00:00:00
abstract::Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116249
更新日期:1988-01-01 00:00:00
abstract::Oxidative stress and generation of reactive oxygen species are believed to be implicated in Parkinson's disease (PD). Erythrocyte activity of superoxide dismutase (SOD) and catalase, the blood glutathione system, and plasma levels of thiobarbituric-acid-reactive substances (TBARS) were measured in 80 PD patients. Thes...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000103641
更新日期:2007-01-01 00:00:00
abstract::A 28-year-old man with negative family history for neuromuscular diseases showed a distal myopathy. Creatine kinase was slightly increased. Two muscle biopsies were performed. The first showed myopathic features, rimmed vacuoles in a limited area and increase of free glycogen; the second showed only nonspecific pathol...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116430
更新日期:1989-01-01 00:00:00
abstract::After briefly evaluating the contraindications and indications of vasoactive and eumetabolic therapy of cerebral ischemia, the paper considers the main drugs at present in use in therapy of the syndrome induced by diffused cerebral arteriosclerosis. Among the drugs with a mainly vasoactive effect, consideration is giv...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115018
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Focal embouchure dystonia (FED) is a type of task-specific dystonia affecting wind instrument players, and it frequently ends their professional careers. The results of the treatments of FED in the reported literature are disappointing. OBJECTIVE:We report 3 patients with FED who were brass instrument playe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000329578
更新日期:2011-01-01 00:00:00
abstract::In order to examine the plasminogen activator (PA) induction involved in the pathogenesis of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS), PA activity in peripheral blood lymphocytes derived from 5 ADEM and 3 MS patients was investigated. There was no PA induction in any ADEM, MS or control ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116971
更新日期:1993-01-01 00:00:00
abstract::Human slow wave sleep (hSWS) is an important form of sleep that seems to take priority over REM sleep. Although hSWS is commonly thought to be associated with enhanced tissue repair, evidence supporting this view is questioned. For example, total sleep deprivation and loss of hSWS have little or no adverse effect on b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116076
更新日期:1986-01-01 00:00:00
abstract::We describe a case presenting continuous muscle fiber activity syndrome, which was slightly reduced by the blocking of nerve conduction and abolished by ischemia. Clinical, electromyographical and bioptical evidence of marked abnormalities of peripheral motoneurons were observed. Association with central motoneuron le...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115508
更新日期:1982-01-01 00:00:00
abstract::Thirty-three headache-free patients (19 F/14 M) suffering from common (n = 9) and classic migraine (n = 19) as well as cluster headache (n = 5) were investigated using the flow tracer 99mTc-hexamethyl propylenamino oxime and single photon emmission computed tomography. A regional decrease of cerebral tracer uptake was...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117334
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke's encephalopathy with cortical abnormalities (WEc). METHODS:We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. RESULTS:Besides the cla...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000235596
更新日期:2009-01-01 00:00:00
abstract::In the last 2 years we have systematically treated 31 sleep apnea patients with 25-50 mg imipramine HCl given 30 min before bedtime. Imipramine treatment was attempted for nonoverweight patients with negative ear, nose and throat (ENT) findings and for patients who had not responded to weight reduction or ENT surgery ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115991
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:The association between edentulism and cerebral small vessel disease is controversial. We aimed to assess this relationship in community-dwelling older adults living in rural Ecuador. METHODS:MRI was performed in 311 (81%) of 385 individuals ≥60 years enrolled in the Atahualpa Project. Participants were cla...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000448839
更新日期:2016-01-01 00:00:00
abstract::197 cases of patients with CVI, subjected to surgery by carotid endarterectomy, are examined. The results were nearly always good and hence the technique is recommended. Particular interest is attached to the risk connected with carotid clamping, through intraoperative study of CBF with 133Xe, such a risk is practical...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115010
更新日期:1978-01-01 00:00:00
abstract::In a direct (door-to-door) epidemiological study, the prevalence rate of cerebrovascular disease in the rural population of northwest Peloponnese, Greece, was found to be 995 strokes per 100,000 inhabitants over 20 years of age. This number is considerably lower than the prevalence rate (1,417 strokes per 100,000 inha...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116408
更新日期:1989-01-01 00:00:00
abstract::The lupus anticoagulant, an immunoglobulin of the IgG or IgM class, is one of a group of antiphospholipid antibodies. Although an anticoagulant in vitro, its action in vivo is that of a procoagulant. This procoagulant activity may involve many organ systems including the nervous system. Thus far cerebral thrombosis, s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115836
更新日期:1985-01-01 00:00:00
abstract::70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115267
更新日期:1981-01-01 00:00:00
abstract::An 18-year-old mongoloid girl (trisomy 21) of Asian descent presented two symptoms rarely associated with mongolism (Down's syndrome). (1) Brain stem calcification; the first case diagnosed in vivo in mongolism on computerized axial tomography. (2) Hallucinatory psychotic depression; the first case successfully treate...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114963
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Patients with multiple sclerosis (MS) report sleep disturbances (SD) and excessive daytime sleepiness (EDS) more frequently than the general population. Our objectives were to evaluate SD and EDS in MS patients and to test the reliability of subjective sleep questionnaires. METHODS:Demographic and clinical ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000335076
更新日期:2012-01-01 00:00:00
abstract::This retrospective study aims to assess cognitive involvement in pre-AIDS, not drug abuser subjects and to determine whether CD4 status or disease stage best correlates with cognitive changes that may portend development of ADC. 328 cases were analyzed. No differences in psychometric performance in relation to CDC sta...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008112
更新日期:1999-01-01 00:00:00
abstract::In a 5-year follow-up of a case of adult metachromatic leukodystrophy, already diagnosed in the preclinical stage, the development of the symptoms of this disease could be studied in detail: initially, lack of drive, emotional lability and depressive mood. At the same time, pain in the arms and beginning gait disturba...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114818
更新日期:1977-01-01 00:00:00
abstract::The efficacy and safety of sumatriptan, a selective 5-HT1-like receptor agonist, were studied in a randomized, double-blind, placebo-controlled, parallel-group, multicentre, multinational clinical trial of 235 patients suffering a moderate to severe migraine attack. Patients were randomized to treat a single migraine ...
journal_title:European neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000116760
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:Newer Scandinavian data on intracerebral hemorrhage (ICH) are scarce. We aimed at providing updated community-based data on the incidence, characteristics and outcome of ICH leading to hospitalization in the southernmost region in Norway. METHODS:We analyzed data from all consecutive patients hospitali...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000336299
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to ascertain the clinical manifestations of granulomatosis with polyangiitis (Wegener's) (GPA) with the involvement of the peripheral nervous system (PNS) and central nervous system (CNS). SUMMARY:All neurologic inpatients in a hospital over a 12-year period were reviewed. Nine pat...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000375492
更新日期:2015-01-01 00:00:00
abstract::Although many studies have been performed on nervous tissue pathology in Guillain-Barré syndrome (GBS), much less is known about pathological changes in skeletal muscle in this disorder. We have studied muscle biopsies from 5 patients with GBS, 5 patients with amyotrophic lateral sclerosis (control A), and 5 patients ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000007924
更新日期:1998-01-01 00:00:00
abstract::Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...
journal_title:European neurology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000107974
更新日期:2007-01-01 00:00:00
abstract::The pathogenesis of Parkinson's disease (PD) has been linked to oxidative-mediated events including increased monoamine oxidase (MAO) and free-radical generation. We are investigating the ability of the MAO inhibitor, selegiline (deprenyl), and of the free-radical scavenger, tocopherol, to delay the onset of disabilit...
journal_title:European neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000116869
更新日期:1992-01-01 00:00:00
abstract::Synaesthesia is the intriguing, involuntary experience of feeling one sensation in response to a different sensory stimulus. Recognised since described in 1890 by John Locke and clarified by Galton in the 1880s, it has been analysed in the last 50 years. Grapheme-colour synaesthesia is the commonest form, but many oth...
journal_title:European neurology
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000098101
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex®) is an add-on therapy for moderate-to-severe multiple sclerosis (MS)-related drug-resistant spasticity (MSS). AIM:The MOVE-2 EU study collected data from everyday clinical practice concerning the effectiveness and tolerability of THC:CBD....
journal_title:European neurology
pub_type: 杂志文章,多中心研究
doi:10.1159/000449413
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study aimed at assessing the feasibility of diffusion tensor imaging (DTI) in multilevel cervical spondylotic myelopathy (MCSM) and quantifying the association between DTI parameters and neuronal status as a whole. METHODS:Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were ob...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000443270
更新日期:2016-01-01 00:00:00