Single photon emission computed tomography with technetium-99m hexamethyl propylenamino oxime in the pain-free interval of migraine and cluster headache.

Abstract:

:Thirty-three headache-free patients (19 F/14 M) suffering from common (n = 9) and classic migraine (n = 19) as well as cluster headache (n = 5) were investigated using the flow tracer 99mTc-hexamethyl propylenamino oxime and single photon emmission computed tomography. A regional decrease of cerebral tracer uptake was observed in 16 patients with common migraine, but only in 3 patients with classic migraine and in no patient with cluster headache. In 10 of 15 cases with hemiplegic symptoms during migraine attack the areas of decreased tracer uptake showed a topographic relationship to neurological deficits. It appears that migraine attacks occur in connection with exacerbations of preexisting changes of neuronal activities, cerebral perfusion and metabolism.

journal_name

Eur Neurol

journal_title

European neurology

authors

Schlake HP,Böttger IG,Grotemeyer KH,Husstedt IW,Vollet B,Schober O,Brune GG

doi

10.1159/000117334

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

153-6

issue

3

eissn

0014-3022

issn

1421-9913

journal_volume

30

pub_type

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