Modifications of cyclic alternating pattern in sleep apnea syndrome.

Abstract:

:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a relative stability of arousal and vegetative activities. In a 62-year-old overweight and heavily snoring man, complaining of excessive daytime sleepiness, three consecutive polysomnograms displayed a highly frequent occurrence of nocturnal apneas (apnea index: 15), mostly obstructive and mixed, limited to non-rapid eye movement sleep stages 1 and 2. The apneic episodes, that never occurred during non-CAP, exclusively appeared during the inhibitory phase B of CAP, whereas the following breathing resumption was mainly induced by an activating phase A pattern. The crucial effect of arousal instability on respiratory control is emphasized.

journal_name

Eur Neurol

journal_title

European neurology

authors

Terzano MG,Parrino L,Spaggiari MC

doi

10.1159/000117353

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

235-40

issue

4

eissn

0014-3022

issn

1421-9913

journal_volume

30

pub_type

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