Postganglionic cholinergic dysautonomia: report of muscle findings in 1 case.

Abstract:

:Heretofore unreported findings in skeletal muscle in a 4th case of pure postganglionic dysautonomia are described. They consist of variation in fiber size, Z line and myofilamentous disorganization, intracytoplasmic inclusions and honeycomb formations. The most striking alterations, however, was excess lipid accumulation without concomitant mitochondrial alterations. Sural nerve histology and cytology were normal. The mechanism of lipid accumulation in skeletal muscle of patients with dysautonomia remains unexplained.

journal_name

Eur Neurol

journal_title

European neurology

authors

Afifi AK,Harik SI,Bergman RA,Mire-Salman J,Bahuth NB

doi

10.1159/000115448

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

8-21

issue

1

eissn

0014-3022

issn

1421-9913

journal_volume

21

pub_type

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