Levodopa-responsive parkinsonism in a patient with Down's syndrome.

Abstract:

:We report a patient with Down's syndrome (DS) who developed progressive parkinsonian symptomatology at the age of 43 years. His parkinsonism was responsive to levodopa/carbidopa, but he developed end of dose wearing off. We discuss basal ganglia and dopamine abnormalities in DS and suggest that DS may be associated with parkinsonism.

journal_name

Eur Neurol

journal_title

European neurology

authors

Singer C,Sanchez-Ramos J,Weiner WJ

doi

10.1159/000117355

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

247-8

issue

5

eissn

0014-3022

issn

1421-9913

journal_volume

30

pub_type

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