Tetrahydrocannabinol:Cannabidiol Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice.

abstract：:A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...

journal_title：European neurology

authors： Mozes B,Pines A,Sayar Y,Kaplinsky N,Frankl O

更新日期：1984-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...

journal_title：European neurology

authors： Tohgi H,Takahashi S,Takahashi H,Tamura K,Yonezawa H

更新日期：1996-01-01 00:00:00

abstract：:This study assessed gender differences in diabetic patients with ischemic stroke with respect to vascular risk factors, clinical features and early outcome. Ischemic stroke was diagnosed in 261 diabetic women and 300 diabetic men of 2,446 ischemic stroke patients included in a prospective stroke registry over 17 years...

journal_title：European neurology

authors： Arboix A,Milian M,Oliveres M,García-Eroles L,Massons J

更新日期：2006-01-01 00:00:00

abstract：:The effect of dosage schedules on plasma drug levels was evaluated in two groups of ambulant epileptic patients, whose treatment with diphenylhydantoin (DPH) or phenobarbital (PB) had been simplified by reducing the daily frequency of the dosage regimens. Although the patients received the same milligram per kilogram ...

journal_title：European neurology

authors： Zaccara G,Galli A

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the clinical symptoms of Angelman syndrome (AS) in adults and to identify the neurological pathways affected in this disease. AS is a neurogenetic disorder resulting due to the deletion or inactivation of the ubiquitin-protein-ligase E3A gene on maternal chromosome 15. SUMMARY:A...

journal_title：European neurology

authors： Giroud M,Daubail B,Khayat N,Chouchane M,Berger E,Muzard E,Medeiros de Bustos E,Thauvin-Robinet C,Faivre L,Masurel A,Darmency-Stamboul V,Huet F,Béjot Y,Giroud M,Moulin T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Profound cellular and biochemical remodeling processes occur in the brain following an ischemic stroke, raising the possibility that we may be able to promote neurological recovery by harnessing the brain's endogenous recovery processes with pharmacological or cell-based therapies. There is a compelling body...

journal_title：European neurology

authors： Hermann DM,Chopp M

更新日期：2014-01-01 00:00:00

abstract：:In a group of 60 patients of which 30 were affected by myasthenia, we used the regional curare test. The results were evaluated from a critical point of view and were then compared with the results obtained by the repetitive stimulation of the circumflex nerve, deriving from deltoid muscle. We considered too the speci...

journal_title：European neurology

authors： Boiardi A,Bussone G,Negri S

更新日期：1977-01-01 00:00:00

abstract：:Anticonvulsant therapy was stopped in 191 epileptic children (109 males and 82 females) after a seizure-free period of at least 2 years, independent of EEG findings, followed up for a minimum of 2 years after withdrawal. Overall, 43 (22.5%) had recurrence of seizures; of these, 79% relapsed within the 1st year after d...

journal_title：European neurology

authors： Mastropaolo C,Tondi M,Carboni F,Manca S,Zoroddu F

更新日期：1992-01-01 00:00:00

abstract：:Embolism from the aneurysmal sac is a rare but possible manifestation of intracranial aneurysm; thrombus formation is probably related to the combined action of turbulent flow and a 'stagnant zone'. Three cases are presented: 2 with giant aneurysms (1 internal carotid and 1 sylvian) and 1 with a large aneurysm of the ...

journal_title：European neurology

authors： Parenti G,Fiori L,Marconi F

更新日期：1992-01-01 00:00:00

abstract：:The effect of phytohemagglutinin (PHA) and pokeweed mitogen (PWM) on blood lymphocytes was studied in multiple sclerosis, patients with acute CNS infections, and healthy controls. No significant differences in lymphocyte proliferation were registered between the group of MS patients and the two other groups, irrespect...

journal_title：European neurology

authors： Kinnman J,Link H,Frydén A

更新日期：1979-01-01 00:00:00

abstract：:Deficits in the cholinergic system are pronounced in dementia with Lewy bodies (DLB) and are more severe in patients with visual hallucinations (VHs). The aim is to identify the occipital glucose metabolism patterns by positron emission tomography (PET) and the changes following donepezil treatment. 13 DLB patients wi...

journal_title：European neurology

authors： Satoh M,Ishikawa H,Meguro K,Kasuya M,Ishii H,Yamaguchi S

更新日期：2010-01-01 00:00:00

abstract：:Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms u...

journal_title：European neurology

authors： Stiasny K

更新日期：2001-01-01 00:00:00

abstract：:We examined interleukin-2 (IL-2) production by phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMs) from 75 untreated myasthenia gravis (MG) patients and 48 control patients. Patients with MG consisted of those with elevated PBM IL-2 production (>1,250 pg/ml; mean + 2SD of the controls) (n = 2...

journal_title：European neurology

authors： Utsugisawa K,Nagane Y,Obara D,Kondoh R,Yonezawa H,Tohgi H

更新日期：2003-01-01 00:00:00

abstract：:Nicorandil, an ATP-sensitive potassium (KATP) channel opener, is known to have protective effects on ischemic injury in heart and brain. One of the most important protective mechanisms is the anti-apoptotic effect on cardiomyocytes and neurons. This study explored the anti-apoptotic effect of nicorandil against neurot...

journal_title：European neurology

authors： Kong J,Ren G,Jia N,Wang Y,Zhang H,Zhang W,Chen B,Cao Y

更新日期：2013-01-01 00:00:00

abstract：:Percussion of the skull dates from a time when there were virtually no radiological methods for examining the skull and brain. Three apparently independent contributions appeared within the years 1893-1895. The sound elicited, tenderness, and auscultatory percussion have each been employed for diagnostic purposes, but...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...

journal_title：European neurology

authors： Caspary EA

更新日期：1977-01-01 00:00:00

abstract：:The central motor pathways were studied with the technique of percutaneous electrical stimulation of the central nervous system in 40 normal volunteers. There were no significant differences between the right and left sides, or between males and females. A linear correlation between the cortical latency (Lcor) or the ...

journal_title：European neurology

authors： Ugawa Y,Genba K,Shimpo T,Mannen T

更新日期：1989-01-01 00:00:00

abstract：:Magnetic resonance imaging and angiography is the technique of choice in the diagnosis and follow-up of cerebral venous thrombosis: Thrombosis appears as an absence of flow void on spin echo images and lack of signal in angiographic techniques. The thrombus signal intensity is different on T1 and T2 spin echo weighted...

journal_title：European neurology

authors： Bianchi D,Maeder P,Bogousslavsky J,Schnyder P,Meuli RA

更新日期：1998-11-01 00:00:00

abstract：:We examined a 29-year-old woman who had language disturbances and memory impairment after a left thalamic infarction. MRI showed injury that was limited to the tuberothalamic artery territory. Beside reduced voice volume and verbal memory trouble, she presented with aspontaneity, loss of psychic self-activation and af...

journal_title：European neurology

authors： Lisovoski F,Koskas P,Dubard T,Dessarts I,Dehen H,Cambier J

更新日期：1993-01-01 00:00:00

abstract：:The pathogenesis of Parkinson's disease (PD) has been linked to oxidative-mediated events including increased monoamine oxidase (MAO) and free-radical generation. We are investigating the ability of the MAO inhibitor, selegiline (deprenyl), and of the free-radical scavenger, tocopherol, to delay the onset of disabilit...

journal_title：European neurology

authors： Shoulson I

更新日期：1992-01-01 00:00:00

abstract：:We examined 29 patients with chronic progressive ganglionopathy of different etiology. Neurophysiological abnormalities were dominated by a widespread decrease in sensory nerve action potential amplitudes, which involved both upper and lower limb nerves, even in patients with asymmetrical or patchy clinical presentati...

journal_title：European neurology

authors： Lauria G,Pareyson D,Sghirlanzoni A

更新日期：2003-01-01 00:00:00

abstract：:The aim of this study was to investigate whether there are clues for a correlation between tumor progression and serum anti-Hu antibody concentration in patients with anti-Hu-associated paraneoplastic neurological syndromes (PNS). 19 patients with anti-Hu-associated PNS were assigned to three groups according to the c...

journal_title：European neurology

authors： Rauer S,Andreou I

更新日期：2002-01-01 00:00:00

abstract：:We report on management strategies and clinical outcomes in 4 cases of acute symptomatic congestive intracranial hypertension associated with cerebral arteriovenous malformations (AVMs). Congestion resulted from high-volume shunts exhausting the drainage capacity of the cerebral venous system in 3 patients, and from s...

journal_title：European neurology

authors： Rosenkranz M,Regelsberger J,Zeumer H,Grzyska U

更新日期：2008-01-01 00:00:00

abstract：:Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...

journal_title：European neurology

authors： Reichmann H,Degoul F,Gold R,Meurers B,Ketelsen UP,Hartmann J,Marsac C,Lestienne P

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:Whereas insomnia is frequent in restless legs syndrome (RLS), little is known about daytime sleepiness. We studied a series of 27 consecutive patients with idiopathic RLS in order to identify the characteristics and evolution of excessive daytime sleepiness (EDS) under dopaminergic treatment. METHODS:P...

journal_title：European neurology

authors： Kallweit U,Siccoli MM,Poryazova R,Werth E,Bassetti CL

更新日期：2009-01-01 00:00:00

abstract：:A 39-year-old intravenous drug user presented with dysarthria and a syndrome of the left cerebellar hemisphere. While in hospital, he developed progressive brainstem findings. Repeated CT scans revealed a lucency in the white matter of the left cerebellar hemisphere. Brainstem auditory and short-latency somatosensory ...

journal_title：European neurology

authors： Lipton RB,Krupp L,Horoupian D,Hershkovitz S,Arezzo JC,Kurtzberg D

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...

journal_title：European neurology

authors： Constantinescu I,Korff CM,Vulliemoz S,Picard F,Seeck M

更新日期：2017-01-01 00:00:00

abstract：:Three patients with unusual presentations of basilar artery ectasia are described: subarachnoid hemorrhage was manifest in one and autonomic dysfunction developed in the other two. Aneurysmal rupture was the cause in the first patient, while compression of the brainstem and/or of the baroreceptor afferences of the IXt...

journal_title：European neurology

authors： Nogues M,Casas Parera I,Starkstein S,Micheli F

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Several treatments are available to treat the immune-mediated chronic inflammatory demyelinating polyneuropathy (CIDP). Among these treatments, intravenous immunoglobulins, corticosteroids and plasma exchanges are validated and widely used. A few immunosuppressive drugs have been tried, but they had little e...

journal_title：European neurology

authors： Vallat JM,Mathis S,Ghorab K,Milor MA,Richard L,Magy L

更新日期：2015-01-01 00:00:00

abstract：:Previous findings regarding the role of TNF-alpha-308 gene polymorphism in multiple sclerosis (MS) are contradictory. The aim of this study was to investigate the possible influence of TNF-alpha-308 polymorphism on MS susceptibility and the MS disease process in a Croatian and Slovenian population. Genotyping was perf...

journal_title：European neurology

authors： Ristić S,Lovrecić L,Starcević-Cizmarević N,Brajenović-Milić B,Sega Jazbec S,Sepcić J,Kapović M,Peterlin B

更新日期：2007-01-01 00:00:00