Abstract:
:Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms under therapy may limit the clinical use of levodopa, especially in severely affected patients. An open pilot study shows that the long-acting dopamine agonist cabergoline is a promising new tool in the treatment of RLS. Results of a double-blind, controlled trial are pending.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Stiasny Kdoi
10.1159/000058050keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
24-6eissn
0014-3022issn
1421-9913pii
ene6a024journal_volume
46 Suppl 1pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract::The effect of oral treatment with acyclovir (ACV) on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia (PHN) was studied in 105 patients with herpes zoster. Forty-seven patients were treated with ACV at a dose of 4 g/day in 5 doses for at least a week; the others did not undergo any kind of...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000117274
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND/AIMS:Whereas insomnia is frequent in restless legs syndrome (RLS), little is known about daytime sleepiness. We studied a series of 27 consecutive patients with idiopathic RLS in order to identify the characteristics and evolution of excessive daytime sleepiness (EDS) under dopaminergic treatment. METHODS:P...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000228261
更新日期:2009-01-01 00:00:00
abstract::We have recently observed a diffuse slowing of brain waves using serial quantitative electroencephalographic (qEEG) examinations in interferon (IFN)-alpha-treated chronic hepatitis C patients. However, it remains unclear how this alteration could be assessed. We evaluated the correlation between the qEEG changes and t...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000062997
更新日期:2002-01-01 00:00:00
abstract::The binding of the dopamine uptake inhibitor [3H]GBR-12935 to postmortem putamen from a control group and patients with Alzheimer's disease/senile dementia of Alzheimer type (AD/SDAT) or vascular dementia (VD) was studied. The binding density (Bmax) in AD/SDAT was significantly reduced to 50% of control. A reduction o...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117341
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000052116
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral infarction (CI) occurring soon after intracerebral hemorrhage (ICH) has been rarely reported. The purpose of the present study was to characterize this condition and discuss the possible pathophysiology. METHOD:We retrospectively studied 6 patients who developed CI within 10 days after ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000098465
更新日期:2007-01-01 00:00:00
abstract::The cerebral hemispheres show prominent involvement in hypertensive encephalopathy far more frequently than the brainstem. Two patients with severe paroxysmally accelerated hypertension associated with brainstem hyperintensity in T2-weighted magnetic resonance images are presented. Both present hyperintense lesions im...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000100015
更新日期:2007-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000345271
更新日期:2013-01-01 00:00:00
abstract::The present report evaluates the suppression of antiepileptic drugs in a group of 608 epileptics. Conditions for the suppression of antiepileptic treatment included a previous seizure-free period of 5 years under medication, and a careful evaluation of individual social and work-related circumstances. The reduction of...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116141
更新日期:1987-01-01 00:00:00
abstract:BACKGROUNDS:It is often difficult to diagnose stroke subtypes at admission, particularly in sinus rhythm cases. Vascular pedicle width (VPW) on chest X-ray (CXR) and maximal P-wave duration (P-max) on electrocardiogram (ECG) are again realized as useful parameters reflecting intravascular volume and atrial conduction s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000382127
更新日期:2015-01-01 00:00:00
abstract::Deficits in the cholinergic system are pronounced in dementia with Lewy bodies (DLB) and are more severe in patients with visual hallucinations (VHs). The aim is to identify the occipital glucose metabolism patterns by positron emission tomography (PET) and the changes following donepezil treatment. 13 DLB patients wi...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000322121
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:To examine the therapeutic effect of intravenous recombinant tissue plasminogen activator (rt-PA) therapy for stroke patients receiving maintenance hemodialysis (HD). methods: Of 600 stroke patients receiving intravenous rt-PA using 0.6 mg/kg alteplase who were enrolled in a multicenter observational study i...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000328792
更新日期:2011-01-01 00:00:00
abstract::Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116656
更新日期:1991-01-01 00:00:00
abstract::This study investigates the remote effects of botulinum toxin injections by examining the motor unit architecture of noninjected distant muscles. In 21 dystonia patients treated with botulinum toxin (n = 11, mean cumulative dose = 815 mU; n = 10, mean cumulative dose = 7,207 mU) and 10 control individuals, a blinded s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008222
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling. Management of MG exacerbations includes plasma exchange and intravenous immunoglobulin (IVI...
journal_title:European neurology
pub_type: 杂志文章,多中心研究
doi:10.1159/000502818
更新日期:2019-01-01 00:00:00
abstract::4 cases with an identical neuromuscular disorder are presented. The disorder was characterized by slowly progressive weakness and wasting of the proximal muscles together with either ocular or bulbar symptoms, fatigability, positive tensilon test, myasthenic response on repetitive nerve stimulations, elevated serum cr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115454
更新日期:1982-01-01 00:00:00
abstract::The effect of thoracic duct lymph drainage (5-34 days) in 12 patients with myasthenia gravis on muscular function has been followed for 5-43 months. Among the results obtained were: (1) During the drainage the myasthenic symptoms decreased markedly after 1-4 days and remained so during the drainage. (2) The doses of c...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114659
更新日期:1975-01-01 00:00:00
abstract::A 28-year-old man with negative family history for neuromuscular diseases showed a distal myopathy. Creatine kinase was slightly increased. Two muscle biopsies were performed. The first showed myopathic features, rimmed vacuoles in a limited area and increase of free glycogen; the second showed only nonspecific pathol...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116430
更新日期:1989-01-01 00:00:00
abstract::Clinical evaluation, quantitative analysis of the EMG, and motor unit fiber density were carried out on 34 selected patients that suffered paralytic poliomyelitis. 50% of the subjects developed a late and slowly progressive weakness. Automatic analysis of the electromyogram showed a great increase in mean amplitude in...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115578
更新日期:1983-01-01 00:00:00
abstract::Three patients with cerebral tumor involving diencephalic midline structures (2 malignant gliomas, 1 craniopharyngioma) and no metabolic abnormalities developed disorientation in time and place or coma with triphasic waves (TW) seen on electroencephalograms. Serial EEG recordings showed persistence or disappearance of...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116614
更新日期:1990-01-01 00:00:00
abstract::This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later. ...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000098474
更新日期:2007-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115635
更新日期:2008-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000007924
更新日期:1998-01-01 00:00:00
abstract::Bilateral choroid plexus papillomas, or villous hypertrophy of the choroid plexus, is a very rare entity that presents serious therapeutical problems in the management of secondary oversecretive hydrocephalus. The authors report the cases of 2 infants affected by this condition, and cured with removal of the lateral v...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117402
更新日期:1997-01-01 00:00:00
abstract::A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115736
更新日期:1984-01-01 00:00:00
abstract::We present a long-term follow-up examination concerning patients with isolated extra-ocular muscle involvement in thyroid-related orbitopathy. Within the previous 13 years we observed 7 patients with endocrine orbitopathy and marked myopathy of the extra-ocular muscles. Five of these patients had no detectable proptos...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000131894
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:We aimed at measuring the positive predictive value (PPV) of data in the French Hospital Medical Information Database (FHD). SUMMARY:This retrospective multicenter study included 31 hospitals from where 56 hospital stays were randomly selected among all hospitalizations for the years 2009 and 2010 with at l...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000438859
更新日期:2015-01-01 00:00:00
abstract::Two prospective projects were started in May 1985 to evaluate the long-term effects of bromocriptine in patients with Parkinson's disease. One of the projects is to see if combination therapy with levodopa and bromocriptine is superior to levodopa alone with regard to the prevention of late side effects of levodopa th...
journal_title:European neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1988-01-01 00:00:00
abstract::Superior orbital fissure syndrome is a symptomatologic complex, consisting of retroorbital pain, paralysis of extraocular muscles, impairment of first trigeminal branches and frequent involvement of the optic nerve. From a review of 130 published cases including two personal observations, it appears that the clinical ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114876
更新日期:1977-01-01 00:00:00
abstract::31 children aged between 6 weeks and 15 years, who had suffered a stroke, were investigated by computer tomography (CT). 8 patients had suffered transient ischemic attacks (TIA), 17 had completed ischemic strokes and 6 had hemorrhagic strokes. The mean interval between the stroke and the first CT investigation was 5 d...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115486
更新日期:1982-01-01 00:00:00