Development of cerebral infarction shortly after intracerebral hemorrhage.

Abstract:

BACKGROUND AND PURPOSE:Cerebral infarction (CI) occurring soon after intracerebral hemorrhage (ICH) has been rarely reported. The purpose of the present study was to characterize this condition and discuss the possible pathophysiology. METHOD:We retrospectively studied 6 patients who developed CI within 10 days after the onset of ICH. RESULTS:The initial ICHs were located in the putamen (n=3), thalamus (n=2) and cerebellum (n=1), and were considered to be caused by hypertension in all of the patients. They showed sudden worsening (n=4) or change in neurologic symptoms (n=2) within 10 days after the initial ICH. Follow-up imaging revealed corresponding lacunar (n=2) and territorial (n=4) infarcts. Possible factors related to the development of new CIs included mechanical compression of cerebral vessels (n=2), dehydration (n=4), hypotension (n=2), infection (n=2) and concomitant small-vessel pathology (n=2). CONCLUSIONS:ICH may predispose certain patients to the development of infarcts through a combination of mechanisms, including mechanical compression of cerebral vessels, hemodynamic instability, inflammation and concomitant small-vessel pathology.

journal_name

Eur Neurol

journal_title

European neurology

authors

Kim CH,Kim JS

doi

10.1159/000098465

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

145-9

issue

3

eissn

0014-3022

issn

1421-9913

pii

000098465

journal_volume

57

pub_type

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