Nomogram for the prediction of unbound phenytoin concentrations in patients on a combined treatment of phenytoin and valproic acid.

abstract：BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is associated with a risk of causing diabetes mellitus and ischemic stroke. However, the association between hs-CRP levels and functional outcome after small-artery occlusion (SAO) is unknown. METHODS:Data for 836 patients diagnosed with SAO were collected from t...

journal_title：European neurology

authors： Gao Y,Liu J,Wang W,Gao C,Yu C,Liu S,Wu J

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Cerebral arteriovenous malformations (AVMs) harbor a network of abnormal vasculatures, namely the nidus between arterial and venous components. The pressure gradient between these two components results in abnormal high-velocity arteriovenous shunts flowing through the nidus and alternate intracranial hemody...

journal_title：European neurology

authors： Chuang YM,Guo W,Lin CP

更新日期：2010-01-01 00:00:00

abstract：:In a 5-year follow-up of a case of adult metachromatic leukodystrophy, already diagnosed in the preclinical stage, the development of the symptoms of this disease could be studied in detail: initially, lack of drive, emotional lability and depressive mood. At the same time, pain in the arms and beginning gait disturba...

journal_title：European neurology

authors： Pilz H,Duensing I,Heipertz R,Seidel D,Lowitzsch K,Hopf HC,Goebel HH

更新日期：1977-01-01 00:00:00

abstract：:This study investigates the remote effects of botulinum toxin injections by examining the motor unit architecture of noninjected distant muscles. In 21 dystonia patients treated with botulinum toxin (n = 11, mean cumulative dose = 815 mU; n = 10, mean cumulative dose = 7,207 mU) and 10 control individuals, a blinded s...

journal_title：European neurology

authors： Fertl E,Schnider P,Schneider B,Auff E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:We aimed at measuring the positive predictive value (PPV) of data in the French Hospital Medical Information Database (FHD). SUMMARY:This retrospective multicenter study included 31 hospitals from where 56 hospital stays were randomly selected among all hospitalizations for the years 2009 and 2010 with at l...

journal_title：European neurology

authors： Giroud M,Hommel M,Benzenine E,Fauconnier J,Béjot Y,Quantin C,FRESCO Study.

更新日期：2015-01-01 00:00:00

abstract：:A 49-year-old alcoholic woman was admitted for convulsions. She died after a 4-week clinical course characterized by a persistent coma with diffuse muscular hypertonia. Post-mortem examination of the brain demonstrated a spongy degeneration and gliosis of the cerebral cortex, limited to the 3rd and the 4th layers. No ...

journal_title：European neurology

authors： Naeije R,Franken L,Jacobovitz D,Flament-Durand J

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Focal embouchure dystonia (FED) is a type of task-specific dystonia affecting wind instrument players, and it frequently ends their professional careers. The results of the treatments of FED in the reported literature are disappointing. OBJECTIVE:We report 3 patients with FED who were brass instrument playe...

journal_title：European neurology

authors： Satoh M,Narita M,Tomimoto H

更新日期：2011-01-01 00:00:00

abstract：:A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...

journal_title：European neurology

authors： Mozes B,Pines A,Sayar Y,Kaplinsky N,Frankl O

更新日期：1984-01-01 00:00:00

abstract：:A 48-year-old woman was referred from Zaire with suspected rabies encephalitis. Survival was 34 days after the onset of symptoms and the diagnosis of rabies was ultimately proven after brain autopsy. Serial neurophysiological investigations, including EEG and multimodality evoked potentials and radiological examinatio...

journal_title：European neurology

authors： Hantson P,Guérit JM,de Tourtchaninoff M,Deconinck B,Mahieu P,Dooms G,Aubert-Tulkens G,Brucher JM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Half of Parkinson's disease (PD) patients with mild cognitive impairment (MCI) develop dementia. We studied topographic distribution of cerebral hypometabolism in PD with different types of MCI. METHODS:This study included 61 nondemented PD patients and 14 age-matched controls. PD patients were grouped into...

journal_title：European neurology

authors： Lyoo CH,Jeong Y,Ryu YH,Rinne JO,Lee MS

更新日期：2010-01-01 00:00:00

abstract：:Electrophysiological findings in 10 patients with polyneuropathy and nonmalignant IgMk plasma cell dyscrasia are reported. The amplitude of sensory action potentials and maximum conduction velocity along the sural and median nerves are related to the structural changes found at the biopsy and to the immunologic result...

journal_title：European neurology

authors： Galassi G,Nemni R

更新日期：1986-01-01 00:00:00

abstract：:In a 14-year follow-up the improvement of language functions and the decrease of EEG abnormalities are described in a girl with the Landau-Kleffner syndrome. In this case, the results of subsequent EEG recordings do not permit conclusions about the course of the aphasia. Disappearance of focal spike and waves, bilater...

journal_title：European neurology

authors： van Dongen HR,Meulstee J,Blauw-van Mourik M,van Harskamp F

更新日期：1989-01-01 00:00:00

abstract：:Cerebrospinal fluid metabolites of dopamine, norepinephrine and serotonin were studied in two groups of left temporal lobe epileptic patients, the only difference between the two groups being that one group had paranoid schizophrenic symptomatology. Homovanillic acid accumulation was decreased in this group. This find...

journal_title：European neurology

authors： Peters JG

更新日期：1979-01-01 00:00:00

abstract：:Since the advent of whole-body CT scanning in 1974, many studies have been made in its application to all parts of the body. One of the most fruitful areas has been CT of the spinal cord. The only limitation appears to be the technique used; there is no substitute for a good technique. We shall first review standard C...

journal_title：European neurology

authors： Ledley RS

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling. Management of MG exacerbations includes plasma exchange and intravenous immunoglobulin (IVI...

journal_title：European neurology

authors： Karelis G,Balasa R,De Bleecker JL,Stuchevskaya T,Villa A,Van Damme P,Lagrange E,Heckmann JM,Nicolle M,Vilciu C,Bril V,Mondou E,Griffin R,Chen J,Henriquez W,Garcia B,Camprubi S,Ayguasanosa J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to ascertain the clinical manifestations of granulomatosis with polyangiitis (Wegener's) (GPA) with the involvement of the peripheral nervous system (PNS) and central nervous system (CNS). SUMMARY:All neurologic inpatients in a hospital over a 12-year period were reviewed. Nine pat...

journal_title：European neurology

authors： Huang YH,Ro LS,Lyu RK,Chang HS,Wu YR,Chang KH,Kuo HC

更新日期：2015-01-01 00:00:00

abstract：:Two cases are presented with a long clinical history of multiple sclerosis (MS) before the diagnosis of an intracranial brain tumor. In the subsequent brain autopsy, however, both cases presented a diffusely growing anaplastic astrocytoma, only, and no changes similar to MS were seen. Diffuse tumor growth was noted in...

journal_title：European neurology

authors： Röyttä M,Latvala M

更新日期：1986-01-01 00:00:00

abstract：:This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later. ...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:The effect of dosage schedules on plasma drug levels was evaluated in two groups of ambulant epileptic patients, whose treatment with diphenylhydantoin (DPH) or phenobarbital (PB) had been simplified by reducing the daily frequency of the dosage regimens. Although the patients received the same milligram per kilogram ...

journal_title：European neurology

authors： Zaccara G,Galli A

更新日期：1979-01-01 00:00:00

abstract：:The gradual intraneuronal accumulation of an insoluble fibrous material which partly consists of abnormally phosphorylated tau protein (neurofibrillary change) represents an important neuropathological hallmark of Alzheimer's disease. Neurofibrillary tangles and neuropil threads formed from this material develop in on...

journal_title：European neurology

authors： Braak H,Braak E,Bohl J

更新日期：1993-01-01 00:00:00

abstract：:In order to examine the plasminogen activator (PA) induction involved in the pathogenesis of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS), PA activity in peripheral blood lymphocytes derived from 5 ADEM and 3 MS patients was investigated. There was no PA induction in any ADEM, MS or control ...

journal_title：European neurology

authors： Sugita K,Suzuki N,Shimizu N,Takanashi J,Ishii M,Niimi N

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Dizziness and vertigo are frequent complaints of outpatients in the neurological department. Our objective was to explore the epidemiological category and clinical features of patients with dizziness or vertigo in the neurological outpatient department of a tertiary hospital. METHODS:We consecutively recrui...

journal_title：European neurology

authors： Pan Q,Zhang Y,Long T,He W,Zhang S,Fan Y,Zhou J

更新日期：2018-01-01 00:00:00

abstract：:The effect of oral treatment with acyclovir (ACV) on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia (PHN) was studied in 105 patients with herpes zoster. Forty-seven patients were treated with ACV at a dose of 4 g/day in 5 doses for at least a week; the others did not undergo any kind of...

journal_title：European neurology

authors： Mondelli M,Romano C,Passero S,Porta PD,Rossi A

更新日期：1996-01-01 00:00:00

abstract：:Fatigue is one of the most frequent and most disabling symptoms in multiple sclerosis (MS). We investigated the possible association of the MS-related fatigue syndrome with the available disease-modifying therapies and the main disease characteristics in a cross-sectional study on 320 consecutive patients. The prevale...

journal_title：European neurology

authors： Putzki N,Katsarava Z,Vago S,Diener HC,Limmroth V

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Seizures and epilepsy are harmful and worsen the disability of stroke patients. There are currently no good clinical predictors of late-onset seizures and epilepsy in patients with cerebrovascular disease (CVD). PATIENTS AND METHODS:110 patients with delayed seizures after an ischaemic or a haemorrhagic str...

journal_title：European neurology

authors： De Reuck J,Goethals M,Vonck K,Van Maele G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to elucidate the influence of insular infarction on blood pressure (BP) variability and outcomes according to the region of the insular cortex affected. METHODS:A total of 90 patients diagnosed with acute unilateral ischemic stroke were registered. The BP variability was calculated...

journal_title：European neurology

authors： Kitamura J,Ueno H,Nagai M,Hosomi N,Honjo K,Nakamori M,Mukai T,Imamura E,Nezu T,Aoki S,Ohshita T,Nomura E,Wakabayashi S,Maruyama H,Matsumoto M

更新日期：2018-01-01 00:00:00

abstract：:In a previous retrospective study, we demonstrated that falls are common and often injurious in dominant spinocerebellar ataxias (SCAs) and that nonataxia features play an important role in these falls. Retrospective surveys are plagued by recall bias for the presence and details of prior falls. We therefore sought to...

journal_title：European neurology

authors： Fonteyn EM,Schmitz-Hübsch T,Verstappen CC,Baliko L,Bloem BR,Boesch S,Bunn L,Giunti P,Globas C,Klockgether T,Melegh B,Pandolfo M,Schöls L,Timmann D,van de Warrenburg BP

更新日期：2013-01-01 00:00:00

abstract：:The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...

journal_title：European neurology

authors： Rocchelli B,Poloni M,Mazzarello P,Delodovici M

更新日期：1983-01-01 00:00:00

abstract：:20 patients who had clinical symptoms and/or signs of compression of the 7th and/or 6th cervical roots were examined. Motor and sensory nerve conduction velocities, velocities in the proximal segment of the median nerve determined by measuring F-wave latencies, cervical somatosensory evoked potentials, and needle elec...

journal_title：European neurology

authors： Tackmann W,Radü EW

更新日期：1983-01-01 00:00:00

abstract：:The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...

journal_title：European neurology

authors： Caspary EA

更新日期：1977-01-01 00:00:00