The Impact of Methylprednisolone Pulses during Relapses of Multiple Sclerosis on the Kinetics of Anti-Interferon-Beta Antibodies.

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now documented by several studies. A major breakthrough has been the discovery of two single-gene defects in familial PD. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein gene has been ...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu HC,Lee CC,Tsai CH,Chang JG

更新日期：2000-01-01 00:00:00

abstract：:It is generally believed that a homonymous defect of macular vision (HMV) is caused by a small lesion restricted to the occipital lobe tip and rarely results from ischemic stroke. The incidence of HMV was studied retrospectively in 54 patients with infarction of the posterior cerebral artery territory who underwent Go...

journal_title：European neurology

authors： Isa K,Miyashita K,Yanagimoto S,Nagatsuka K,Naritomi H

更新日期：2001-01-01 00:00:00

abstract：:Two cases of lithium neurotoxic effects are reported. Both cases are expressed by choreoathetotic movements and in both of them intoxication was caused by combined drug therapy. In our opinion caution is advised when lithium is administered in combination with drugs, especially in elderly patients. ...

journal_title：European neurology

authors： Walevski A,Radwan M

更新日期：1986-01-01 00:00:00

abstract：:The efficacy of the 5-HT1 receptor agonist sumatriptan in the acute treatment of migraine has been investigated in an extensive programme of controlled clinical trials. Sumatriptan provided rapid relief from migraine headache with onset of relief occurring within 10 min of a 6 mg subcutaneous injection and within 30 m...

journal_title：European neurology

authors： Pilgrim AJ

更新日期：1994-01-01 00:00:00

abstract：:70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...

journal_title：European neurology

authors： Zhao BX,Liu XQ,Guo YP,Yang YC,Huang HF

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND/AIMS:Whereas insomnia is frequent in restless legs syndrome (RLS), little is known about daytime sleepiness. We studied a series of 27 consecutive patients with idiopathic RLS in order to identify the characteristics and evolution of excessive daytime sleepiness (EDS) under dopaminergic treatment. METHODS:P...

journal_title：European neurology

authors： Kallweit U,Siccoli MM,Poryazova R,Werth E,Bassetti CL

更新日期：2009-01-01 00:00:00

abstract：:In recent years, the involvement of the immune system in acquired forms of cerebellar ataxia has been frequently demonstrated. In this study, we describe 6 out of 49 patients with subacute or chronic progressive cerebellar ataxia in whom antibodies against neuronal and non-neuronal antigens were identified. Two women ...

journal_title：European neurology

authors： Fancellu R,Pareyson D,Corsini E,Salsano E,Laurà M,Bernardi G,Antozzi C,Andreetta F,Colecchia M,Di Donato S,Mariotti C

更新日期：2009-01-01 00:00:00

abstract：:The clinical and biochemical data on 13 patients with Batten's syndrome are described. Clinically the disease was characterized by progressive maental and somatic deterioration. Initially, vision loss was found between the ages 4 and 8 years. This was associated with 1 or 2 years of normal school attendance followed b...

journal_title：European neurology

authors： Jensen GE,Clausen J,Melchior JC,Konat G

更新日期：1977-01-01 00:00:00

abstract：:The authors describe a case where a parkinsonian symptomatology is associated with pneumoencephalographic and RISA-cisternographic findings typical of an occult normal pressure hydrocephalus. They discuss their personal contribution in the light of what has been already reported in the literature on the same subject. ...

journal_title：European neurology

authors： Mazza S,Laudisio A,Bergonzi P

更新日期：1976-01-01 00:00:00

abstract：:The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...

journal_title：European neurology

authors： Houshmand M,Sanati MH,Rashedi I,Sharifpanah F,Asghari E,Lotfi J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Several treatments are available to treat the immune-mediated chronic inflammatory demyelinating polyneuropathy (CIDP). Among these treatments, intravenous immunoglobulins, corticosteroids and plasma exchanges are validated and widely used. A few immunosuppressive drugs have been tried, but they had little e...

journal_title：European neurology

authors： Vallat JM,Mathis S,Ghorab K,Milor MA,Richard L,Magy L

更新日期：2015-01-01 00:00:00

abstract：:We report a laser microprobe mass analysis of aluminum and iron content in the hippocampus and in the inferior temporal cortex in 2 cases of dementia pugilistica (DP), 4 cases of Alzheimer's disease (AD), and 3 controls. There was a predominant accumulation of Al and Fe within neurofibrillary tangles (NFT) in both DP ...

journal_title：European neurology

authors： Bouras C,Giannakopoulos P,Good PF,Hsu A,Hof PR,Perl DP

更新日期：1997-01-01 00:00:00

abstract：:Continuing the previously published clinical development of a case of adult metachromatic leukodystrophy (MLD), we now describe the terminal phase and death (at 46 years of age) of our patient. The final phase was characterized clinically by progression of generalized peripheral neuropathy, advanced extrapyramidal and...

journal_title：European neurology

authors： Seidel D,Heipertz R,Goebel HH,Duensing I,Pilz H

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex®) is an add-on therapy for moderate-to-severe multiple sclerosis (MS)-related drug-resistant spasticity (MSS). AIM:The MOVE-2 EU study collected data from everyday clinical practice concerning the effectiveness and tolerability of THC:CBD....

journal_title：European neurology

authors： Vermersch P,Trojano M

更新日期：2016-01-01 00:00:00

abstract：:To clarify the function of human atrial natriuretic peptide (hANP) in the cerebrospinal fluid (CSF), we examined hANP levels in the CSF of patients with various neurological diseases. The subjects were 16 controls without neurological disease and 45 patients with neurological disease. The 45 patients with neurological...

journal_title：European neurology

authors： Yamasaki H,Sugino M,Ohsawa N

更新日期：1997-01-01 00:00:00

abstract：:Reviewing the angiograms of 100 patients with RIA or stroke we found intracranial lesions in 67%, extracranial lesions in 64%, and normal angiograms in 13% of the cases. Risk factors occurred more often as the angiographic lesions were more extensive. These findings confirm the importance of angiographic examination o...

journal_title：European neurology

authors： van Oudenaarden WF,Tans JT,Hoogland PH

更新日期：1980-01-01 00:00:00

abstract：:The importance of patent foramen ovale (PFO) has long been discussed in the literature in relation to different coexisting medical conditions. Many researchers focused on the occurrence of PFO in ischemic stroke patients, especially in the subgroup of young patients with a recurrent event. Unfortunately, before establ...

journal_title：European neurology

authors： Piechowski-Jozwiak B,Bogousslavsky J

更新日期：2013-01-01 00:00:00

abstract：:SJL/J mice have been studied as the model animals for autoimmunological diseases. Recently it was clarified that SJL/J mice have a defect of dysferlin. Human limb girdle muscular dystrophy 2B and Miyoshi myopathy also have a defect of dysferlin. In this study we present the histological and immunohistological changes ...

journal_title：European neurology

authors： Nemoto H,Konno S,Nakazora H,Miura H,Kurihara T

更新日期：2007-01-01 00:00:00

abstract：:64 patients on hemodialysis were investigated. The mean duration of dialysis was 43 months. In all the patients, serum aluminium levels, systolic blood pressure (averaged over a period of 6 weeks) and the EEG were investigated. Psychological testing to assess the level of intelligence (IQ) was also performed. The seru...

journal_title：European neurology

authors： Ladurner G,Wawschinek O,Pogglitsch H,Petek W,Urlesberger H,Holzer H

更新日期：1982-01-01 00:00:00

abstract：:A patient who on presentation fulfilled diagnostic criteria for benign intracranial hypertension subsequently developed a lymphocytic meningitis. A final diagnosis of neurosarcoidosis was made and the patient responded well to oral steroids. ...

journal_title：European neurology

authors： Redwood MD,Winer JB,Rossor M

更新日期：1990-01-01 00:00:00

abstract：:Magnetic resonance imaging and angiography is the technique of choice in the diagnosis and follow-up of cerebral venous thrombosis: Thrombosis appears as an absence of flow void on spin echo images and lack of signal in angiographic techniques. The thrombus signal intensity is different on T1 and T2 spin echo weighted...

journal_title：European neurology

authors： Bianchi D,Maeder P,Bogousslavsky J,Schnyder P,Meuli RA

更新日期：1998-11-01 00:00:00

abstract：AIMS:To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy in a European country. METHODS:A cross-sectional questionnaire survey. The questionnaire was distributed by the medical staff in different outpatient waiting rooms (obstetrics and gynecology department of the univ...

journal_title：European neurology

authors： Neau JP,Porcheron A,Mathis S,Julian A,Meurice JC,Paquereau J,Godeneche G,Ciron J,Bouche G

更新日期：2010-01-01 00:00:00

abstract：:We report a 17-year-old patient who presented a chronic relapsing sensorimotor demyelinating neuropathy with 6 relapses over a 7-year period, preceding by 4 years the diagnosis of a multicentric angiofollicular lymph node hyperplasia. A role for Epstein-Barr virus (EBV) as a trigger of the neuropathy may be suggested ...

journal_title：European neurology

authors： Vingerhoets F,Kuntzer T,Delacrétaz,Steck AJ,Knecht H,Bogousslavsky J,Meier C,Regli F

更新日期：1995-01-01 00:00:00

abstract：:This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later. ...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:Neurodegenerative tauopathies may be inherited as autosomal-dominant disorders with variable clinicopathological phenotypes, and causative mutations in the microtubule-associated protein tau (MAPT) gene are not regularly seen. Herein, we describe a patient with clinically typical and autopsy-proven corticobasal degene...

journal_title：European neurology

authors： Jung HH,Bremer J,Streffer J,Virdee K,Spillantini MG,Crowther RA,Brugger P,Van Broeckhoven C,Aguzzi A,Tolnay M

更新日期：2012-01-01 00:00:00

abstract：:The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...

journal_title：European neurology

authors： Rocchelli B,Poloni M,Mazzarello P,Delodovici M

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. METHODS:We ...

journal_title：European neurology

authors： Jin J,Hu F,Qin X,Liu X,Li M,Dang Y,Dang J

更新日期：2018-01-01 00:00:00

abstract：:A case of Fisher's syndrome which recurred 10 years apart was reported. Laterality of cranial nerve findings in the initial episode was replicated in the recurrence. Some kind of localized immune sensitization is supposed to play a role in replicating such a laterality. Increased CD4/CD8 ratio and elevated IgE were no...

journal_title：European neurology

authors： Uchihara T,Ikeda M,Tsukagoshi H

更新日期：1991-01-01 00:00:00

abstract：:Although repetitive transcranial magnetic stimulation (rTMS) for hemiparesis is beneficial, so far no study has examined the usefulness of rTMS for apathy. Thirteen patients with chronic stroke were assigned randomly to 2 groups: rTMS group (n = 7) and sham stimulation group (n = 6). The patients received 5 sessions o...

journal_title：European neurology

authors： Sasaki N,Hara T,Yamada N,Niimi M,Kakuda W,Abo M

更新日期：2017-01-01 00:00:00

abstract：:So-called apraxia of eyelid opening (scAEO) has been described chiefly in the context of extrapyramidal disorders. We described 10 new patients with scAEO developing in the absence of any other CNS sign and reviewed the 11 cases with isolated scAEO reported in the literature. Combining our patients and those from the ...

journal_title：European neurology

authors： Defazio G,Livrea P,Lamberti P,De Salvia R,Laddomada G,Giorelli M,Ferrari E

更新日期：1998-01-01 00:00:00