Isolated so-called apraxia of eyelid opening: report of 10 cases and a review of the literature.

Abstract:

:So-called apraxia of eyelid opening (scAEO) has been described chiefly in the context of extrapyramidal disorders. We described 10 new patients with scAEO developing in the absence of any other CNS sign and reviewed the 11 cases with isolated scAEO reported in the literature. Combining our patients and those from the literature, peak age at onset was in the 6th decade and there was a female preponderance of 2:1. The characteristic inability to initiate lid elevation was frequently associated with failure to sustain lid elevation, thus suggesting that eyelid motor control may be abnormal in isolated scAEO. Antecedent events included ocular signs and symptoms consistent with diseases of eyes or face (4 cases in our series and 2 in the literature), chronic treatment with flunarizine (1 case), and family history of dystonia (1 case). Flunarizine discontinuation led to sustained remission of the eyelid disturbance. Overall, these clues suggest the involvement of the extrapyramidal system in the pathophysiology of isolated scAEO. Familial clustering of isolated scAEO in one of our patients may be in favor of a genetic contribution. In our series, botulinum toxin administration close to the pretarsal part of the orbicularis oculi muscle significantly improved scAEO in 8/10 cases, whereas orbital/preseptal injection had no effect. We conclude that the term 'apraxia' may not be the correct descriptive term even when the eyelid disturbance occurs without any other CNS disease.

journal_name

Eur Neurol

journal_title

European neurology

authors

Defazio G,Livrea P,Lamberti P,De Salvia R,Laddomada G,Giorelli M,Ferrari E

doi

10.1159/000007935

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

204-10

issue

4

eissn

0014-3022

issn

1421-9913

pii

ene39204

journal_volume

39

pub_type

杂志文章,评审
  • Motor disturbance and brain functional imaging in Parkinson's disease.

    abstract::18F-Dopa positron emission tomography (PET) provides a sensitive means of quantitating the loss of nigrostriatal dopaminergic fibres in Parkinson's disease and so can be used to diagnose its presence and to objectively follow the rate of disease progression. It can also be used, in principle, to determine the efficacy...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000113473

    authors: Brooks DJ

    更新日期:1997-01-01 00:00:00

  • Central neuroblastic tumour associated with smooth muscle fibers. A study in the optic and electron microscopes.

    abstract::The present paper is a study of a microcystic intraspinal tumour that developed in a 4-year-old child. The histologic examination showed the presence of neuroblastic elements developing next to smooth muscle fibers. The tumour had diffusely invaded the meninges, presenting a marked collagen reaction. Ultrastructurally...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114682

    authors: Vuia O,Hager H

    更新日期:1975-01-01 00:00:00

  • Autosomal dominant familial Parkinson disease: older onset of age, and good response to levodopa therapy.

    abstract::Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000113460

    authors: Hasegawa K,Kowa H

    更新日期:1997-01-01 00:00:00

  • The Development of Sayk's Cell Sedimentation Chamber: A Historical View on Clinical Cerebrospinal Fluid Diagnostics.

    abstract:OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Mor...

    journal_title:European neurology

    pub_type: 历史文章,杂志文章

    doi:10.1159/000456003

    authors: Dahlmann N,Zettl UK,Kumbier E

    更新日期:2017-01-01 00:00:00

  • The Efficacy of High-Frequency Repetitive Transcranial Magnetic Stimulation for Improving Apathy in Chronic Stroke Patients.

    abstract::Although repetitive transcranial magnetic stimulation (rTMS) for hemiparesis is beneficial, so far no study has examined the usefulness of rTMS for apathy. Thirteen patients with chronic stroke were assigned randomly to 2 groups: rTMS group (n = 7) and sham stimulation group (n = 6). The patients received 5 sessions o...

    journal_title:European neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000477440

    authors: Sasaki N,Hara T,Yamada N,Niimi M,Kakuda W,Abo M

    更新日期:2017-01-01 00:00:00

  • Continuous muscle activity and distal spinal muscular atrophy.

    abstract::A young man presented with myokymias, cramp-like difficulty in muscle relaxation and peroneal atrophy. EMG studies revealed continuous muscle activity (CMA) manifested as grouped potentials and high frequency discharges. Sensory nerve conduction studies and sural nerve biopsy gave normal results, and he was thought to...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116667

    authors: Castilla JM,Alberca R,Chinchon I,Gil-Neciga E,Rafel E

    更新日期:1991-01-01 00:00:00

  • Nocturnal complex partial seizures precipitated by REM sleep. A case report.

    abstract::A 16-year-old patient presenting with complex partial seizures occurring in the transition from a REM period to wakefulness is described. His baseline EEG showed generalized and symmetrical slow spike and wave complexes, on a normal background activity, activated by NREM sleep. Polygraphic and videotape recordings, ca...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116383

    authors: Silvestri R,De Domenico P,Musolino R,Mento G,Marabello L,Longo M,Di Perri R

    更新日期:1989-01-01 00:00:00

  • Therapies in muscular dystrophy: current concepts and future prospects.

    abstract::In the fast moving field of muscular dystrophy, therapeutic matters are now high on the agenda. Despite little progress made in the understanding of the exact pathogenesis, hopes have been raised with the advent of molecular medicine applied to such disorders. A constellation of techniques or therapeutic solutions are...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000008150

    authors: Urtizberea JA

    更新日期:2000-01-01 00:00:00

  • Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer's disease.

    abstract::Nicorandil, an ATP-sensitive potassium (KATP) channel opener, is known to have protective effects on ischemic injury in heart and brain. One of the most important protective mechanisms is the anti-apoptotic effect on cardiomyocytes and neurons. This study explored the anti-apoptotic effect of nicorandil against neurot...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000351247

    authors: Kong J,Ren G,Jia N,Wang Y,Zhang H,Zhang W,Chen B,Cao Y

    更新日期:2013-01-01 00:00:00

  • Three cases of focal embouchure dystonia: classifications and successful therapy using a dental splint.

    abstract:BACKGROUND:Focal embouchure dystonia (FED) is a type of task-specific dystonia affecting wind instrument players, and it frequently ends their professional careers. The results of the treatments of FED in the reported literature are disappointing. OBJECTIVE:We report 3 patients with FED who were brass instrument playe...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000329578

    authors: Satoh M,Narita M,Tomimoto H

    更新日期:2011-01-01 00:00:00

  • The clinical profile of sumatriptan: efficacy in migraine.

    abstract::The efficacy of the 5-HT1 receptor agonist sumatriptan in the acute treatment of migraine has been investigated in an extensive programme of controlled clinical trials. Sumatriptan provided rapid relief from migraine headache with onset of relief occurring within 10 min of a 6 mg subcutaneous injection and within 30 m...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000119529

    authors: Pilgrim AJ

    更新日期:1994-01-01 00:00:00

  • Location-dependent patterns in cardio-autonomic dysfunction in ischaemic stroke.

    abstract:BACKGROUND AND STUDY PURPOSE:Autonomic nervous system dysfunction is a common complication of acute cerebrovascular disorders. The aim of this study was to investigate a possible location-dependent difference in cardio-autonomic function in patients with ischaemic stroke. PATIENTS AND METHODS:Sympathetic function was ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000070856

    authors: Strittmatter M,Meyer S,Fischer C,Georg T,Schmitz B

    更新日期:2003-01-01 00:00:00

  • Amyotrophic lateral sclerosis and frontal lobe dementia in Alzheimer's disease. Case report and review of the literature.

    abstract::Clinicopathological data of a woman with a 3-year course of concurrent amyotrophic lateral sclerosis and dementia are presented. Dementia had occurred at time of onset of motor disturbances and presented as typical frontal lobe dementia. Pathology confirmed motor neuron disease of amyotrophic lateral sclerosis and fro...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000116962

    authors: Müller M,Vieregge P,Reusche E,Ogomori K

    更新日期:1993-01-01 00:00:00

  • Clinical and CSF findings in multiple sclerosis patients with or without IgG oligoclonal bands at isoelectric focusing examination of CSF and serum proteins.

    abstract::The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115534

    authors: Rocchelli B,Poloni M,Mazzarello P,Delodovici M

    更新日期:1983-01-01 00:00:00

  • Immediate transition from a petit mal absence into a grand mal seizure. Case report.

    abstract::Petit mal absences in childhood are often followed by grand mal seizures in adolescence and a coexistence of both types of seizures is not uncommon at all. It is noteworthy, however, that such a coexistence does not imply immediate transition from one type of seizure into the other one. Hence, a grand mal attack may b...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114721

    authors: Niedermeyer E

    更新日期:1976-01-01 00:00:00

  • Impact of Rivastigmine on Cognitive Dysfunction and Falling in Parkinson's Disease Patients.

    abstract:BACKGROUND:The purpose of this study was to observe the incidence of falls in Parkinson's disease (PD) patients with different cognitive levels and to investigate the effect of the cholinesterase inhibitor Rivastigmine on cognitive dysfunction and falling in PD patients. SUBJECTS AND METHODS:Data from 176 PD patients ...

    journal_title:European neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000438824

    authors: Li Z,Yu Z,Zhang J,Wang J,Sun C,Wang P,Zhang J

    更新日期:2015-01-01 00:00:00

  • Chronic relapsing neuropathy associated with Castleman's disease (angiofollicular lymph node hyperplasia).

    abstract::We report a 17-year-old patient who presented a chronic relapsing sensorimotor demyelinating neuropathy with 6 relapses over a 7-year period, preceding by 4 years the diagnosis of a multicentric angiofollicular lymph node hyperplasia. A role for Epstein-Barr virus (EBV) as a trigger of the neuropathy may be suggested ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000117156

    authors: Vingerhoets F,Kuntzer T,Delacrétaz,Steck AJ,Knecht H,Bogousslavsky J,Meier C,Regli F

    更新日期:1995-01-01 00:00:00

  • Alfred Vulpian and Jean-Martin Charcot in each other's shadow? From Castor and Pollux at La Salpêtrière to neurology forever.

    abstract::While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both star...

    journal_title:European neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1159/000325733

    authors: Bogousslavsky J,Walusinski O,Moulin T

    更新日期:2011-01-01 00:00:00

  • Synaesthesia.

    abstract::Synaesthesia is the intriguing, involuntary experience of feeling one sensation in response to a different sensory stimulus. Recognised since described in 1890 by John Locke and clarified by Galton in the 1880s, it has been analysed in the last 50 years. Grapheme-colour synaesthesia is the commonest form, but many oth...

    journal_title:European neurology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000098101

    authors: Pearce JM

    更新日期:2007-01-01 00:00:00

  • HTLV-I-associated myelopathy and adult T-cell leukemia cases in a family.

    abstract::Familial cases of HTLV-I-associated myelopathy (HAM) and adult T-cell leukemia (ATL), developing in a daughter and father, respectively, are reported. The coexistence of both diseases in a family has not been reported before. This supports the recent findings that ATL and HAM may be brought about by an identical virus...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116373

    authors: Shoji H,Kuwasaki N,Natori H,Kaji M,Miyamoto Y,Usuku K,Sonoda S,Osame M

    更新日期:1989-01-01 00:00:00

  • Malpighi and the discovery of capillaries.

    abstract::Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...

    journal_title:European neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1159/000107974

    authors: Pearce JM

    更新日期:2007-01-01 00:00:00

  • Clinical predictors of late-onset seizures and epilepsy in patients with cerebrovascular disease.

    abstract:BACKGROUND:Seizures and epilepsy are harmful and worsen the disability of stroke patients. There are currently no good clinical predictors of late-onset seizures and epilepsy in patients with cerebrovascular disease (CVD). PATIENTS AND METHODS:110 patients with delayed seizures after an ischaemic or a haemorrhagic str...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000087715

    authors: De Reuck J,Goethals M,Vonck K,Van Maele G

    更新日期:2005-01-01 00:00:00

  • Association between renal function and clinical outcome in patients with acute stroke.

    abstract:BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000285165

    authors: Hao Z,Wu B,Lin S,Kong FY,Tao WD,Wang DR,Liu M

    更新日期:2010-01-01 00:00:00

  • Angelman syndrome: a case series assessing neurological issues in adulthood.

    abstract:BACKGROUND:This study aimed to evaluate the clinical symptoms of Angelman syndrome (AS) in adults and to identify the neurological pathways affected in this disease. AS is a neurogenetic disorder resulting due to the deletion or inactivation of the ubiquitin-protein-ligase E3A gene on maternal chromosome 15. SUMMARY:A...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000369454

    authors: Giroud M,Daubail B,Khayat N,Chouchane M,Berger E,Muzard E,Medeiros de Bustos E,Thauvin-Robinet C,Faivre L,Masurel A,Darmency-Stamboul V,Huet F,Béjot Y,Giroud M,Moulin T

    更新日期:2015-01-01 00:00:00

  • Clinical, biochemical and neuroimaging parameters after thrombolytic therapy predict long-term stroke outcome.

    abstract:INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000215876

    authors: Brouns R,Sheorajpanday R,Kunnen J,De Surgeloose D,De Deyn PP

    更新日期:2009-01-01 00:00:00

  • Wernicke's encephalopathy with cortical abnormalities: clinicoradiological features: report of 3 new cases and review of the literature.

    abstract:OBJECTIVE:To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke's encephalopathy with cortical abnormalities (WEc). METHODS:We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. RESULTS:Besides the cla...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000235596

    authors: Sakurai K,Sasaki S,Hara M,Yamawaki T,Shibamoto Y

    更新日期:2009-01-01 00:00:00

  • Lack of association between Leber's hereditary optic neuropathy primary point mutations and multiple sclerosis in Iran.

    abstract::The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000075518

    authors: Houshmand M,Sanati MH,Rashedi I,Sharifpanah F,Asghari E,Lotfi J

    更新日期:2004-01-01 00:00:00

  • European Association of Young Neurologists and Trainees: position paper on teaching courses for Generation Y.

    abstract::The European Association of Young Neurologists and Trainees (EAYNT) is a non-profit organization which acts on behalf of young neurologists in Europe and concertedly exerts influence on the formation of a new generation of neurologists [Struhal et al.: Eur J Neurol 2009;16:e146-e148]. This concerns particularly the Ge...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000327696

    authors: Struhal W,Falup-Pecurariu C,Sztriha LK,Grisold W,Sellner J

    更新日期:2011-01-01 00:00:00

  • Correlations between clinical and magnetic resonance imaging findings in multiple sclerosis.

    abstract::40 patients with multiple sclerosis were investigated by magnetic resonance imaging (MRI) and computer tomography (CT). Additionally, cerebrospinal fluid (CSF) findings and evoked potentials (EPs; visual, brainstem) were evaluated. MRI findings were abnormal in 85% of the patients, whilst CT scan showed pathological c...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116269

    authors: Boné G,Ladurner G,Artmann W,Bsteh C

    更新日期:1988-01-01 00:00:00

  • Clinical and myopathological characteristics of desminopathy caused by a mutation in desmin tail domain.

    abstract:BACKGROUND:Most of the previously described pathogenic mutations in desmin are located in highly conserved α-helical domains that play an important role in intermediate filament assembly. The role of the C-terminus non-α-helical 'tail' domain is much less investigated and until recently mutations in this domain have be...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000341617

    authors: Maddison P,Damian MS,Sewry C,McGorrian C,Winer JB,Odgerel Z,Shatunov A,Lee HS,Goldfarb LG

    更新日期:2012-01-01 00:00:00