Abstract:
:Petit mal absences in childhood are often followed by grand mal seizures in adolescence and a coexistence of both types of seizures is not uncommon at all. It is noteworthy, however, that such a coexistence does not imply immediate transition from one type of seizure into the other one. Hence, a grand mal attack may be prepared by all sorts of focal seizures, psychomotor automatisms or bilateral-synchronous myoclonus but immediately preceding petit mal (with generalized spike-wave discharges) is probably extremely rare. The presented case is characterized by unusually late onset of petit mal and grand mal seizures at age 32 and, following a mild head injury, a few episodes of petit mal status (ictal stupor) at age 52. At that time, a series of petit mal absences and eventually a smooth transition from petit mal to grand mal could be recorded. Uncommon frequency characteristics (especially some interspersed spiking at a rate of 9-15/sec) were found at the onset of the ictal spike-wave activity during the petit mal absences. This is regarded as the expression of failing inhibitory mechanisms which generally prevent the immediate development of a grand mal out of a petit mal absence.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Niedermeyer Edoi
10.1159/000114721subject
Has Abstractpub_date
1976-01-01 00:00:00pages
11-6issue
1eissn
0014-3022issn
1421-9913journal_volume
14pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000285165
更新日期:2010-01-01 00:00:00
abstract:AIM:To determine the frequency of epilepsies in the family members of epileptic patients. METHODS:The records of 4,851 patients with epilepsy were reviewed. The frequency and patterns of different epilepsies and epileptic syndromes in the patients, number of affected relatives and consanguinity were studied. RESULTS:...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000322125
更新日期:2011-01-01 00:00:00
abstract::Tardive dyskinesia (TD) induced by antipsychotic drugs represents a great concern for patients and psychiatrists. Considering its pathophysiological mechanisms, there exists a convergence towards the development of postsynaptic dopaminergic hypersensitivity as a possible cause of TD. Hypersensitivity following recepto...
journal_title:European neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000116678
更新日期:1991-01-01 00:00:00
abstract::3 out of 24 patients with mitral valve prolapse (MVP), mean age 25.7 +/- 3.1 displayed markedly thickened redundant and shaggy mitral leaflets in the two-dimensional echocardiogram. The anterior leaflet appeared in the parasternal long axis plane club-shaped in diastole. These three female patients had a history of is...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115766
更新日期:1985-01-01 00:00:00
abstract::The authors describe a case where a parkinsonian symptomatology is associated with pneumoencephalographic and RISA-cisternographic findings typical of an occult normal pressure hydrocephalus. They discuss their personal contribution in the light of what has been already reported in the literature on the same subject. ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114724
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Patients with multiple sclerosis (MS) report sleep disturbances (SD) and excessive daytime sleepiness (EDS) more frequently than the general population. Our objectives were to evaluate SD and EDS in MS patients and to test the reliability of subjective sleep questionnaires. METHODS:Demographic and clinical ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000335076
更新日期:2012-01-01 00:00:00
abstract::In a previous retrospective study, we demonstrated that falls are common and often injurious in dominant spinocerebellar ataxias (SCAs) and that nonataxia features play an important role in these falls. Retrospective surveys are plagued by recall bias for the presence and details of prior falls. We therefore sought to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000342907
更新日期:2013-01-01 00:00:00
abstract::Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116249
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:ANO10 mutations have recently been reported in autosomal recessive cerebellar ataxia type 3 (ARCA3). The objective of this study was to describe the phenotype of 2 siblings with compound heterozygous ANO10 mutations and progressive cerebellar ataxia, epilepsy, and cognitive impairment. A porencephalic cyst w...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000445109
更新日期:2016-01-01 00:00:00
abstract::A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116120
更新日期:1987-01-01 00:00:00
abstract::Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000113399
更新日期:1997-01-01 00:00:00
abstract::64 patients on hemodialysis were investigated. The mean duration of dialysis was 43 months. In all the patients, serum aluminium levels, systolic blood pressure (averaged over a period of 6 weeks) and the EEG were investigated. Psychological testing to assess the level of intelligence (IQ) was also performed. The seru...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115500
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND AND STUDY PURPOSE:Autonomic nervous system dysfunction is a common complication of acute cerebrovascular disorders. The aim of this study was to investigate a possible location-dependent difference in cardio-autonomic function in patients with ischaemic stroke. PATIENTS AND METHODS:Sympathetic function was ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000070856
更新日期:2003-01-01 00:00:00
abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116350
更新日期:1987-01-01 00:00:00
abstract::Seventy-eight asymptomatic HIV-seropositive (aHIV) subjects were examined by means of an extensive neuropsychological test battery in comparison with 32 HIV-seronegative controls. They were also tested with regard to CD4+ and serum p24 antigen. Fifty-six of them completed a clinical follow-up of 12 up to 36 months and...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117228
更新日期:1996-01-01 00:00:00
abstract::The efficacy of the 5-HT1 receptor agonist sumatriptan in the acute treatment of migraine has been investigated in an extensive programme of controlled clinical trials. Sumatriptan provided rapid relief from migraine headache with onset of relief occurring within 10 min of a 6 mg subcutaneous injection and within 30 m...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000119529
更新日期:1994-01-01 00:00:00
abstract::Automatic analysis of EMG (T/A analysis) and invasive muscle fiber conduction velocity in situ (MFCV) were performed in 15 patients after traumatic lesions of the knee and immobilization with quadriceps atrophy. T/A analysis showed transient reduced number of turns, consistent with inhibition of quadriceps motoneurons...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008145
更新日期:2000-01-01 00:00:00
abstract::Continuing the previously published clinical development of a case of adult metachromatic leukodystrophy (MLD), we now describe the terminal phase and death (at 46 years of age) of our patient. The final phase was characterized clinically by progression of generalized peripheral neuropathy, advanced extrapyramidal and...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115164
更新日期:1980-01-01 00:00:00
abstract::The European Association of Young Neurologists and Trainees (EAYNT) is a non-profit organization which acts on behalf of young neurologists in Europe and concertedly exerts influence on the formation of a new generation of neurologists [Struhal et al.: Eur J Neurol 2009;16:e146-e148]. This concerns particularly the Ge...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000327696
更新日期:2011-01-01 00:00:00
abstract::This study assessed gender differences in diabetic patients with ischemic stroke with respect to vascular risk factors, clinical features and early outcome. Ischemic stroke was diagnosed in 261 diabetic women and 300 diabetic men of 2,446 ischemic stroke patients included in a prospective stroke registry over 17 years...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000094249
更新日期:2006-01-01 00:00:00
abstract::In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116233
更新日期:1988-01-01 00:00:00
abstract::This lecture is mainly concerned with questions about how hemodynamic conditions in atherosclerotic arteries affect arriving platelets that aggregate there and about the chemical agents responsible for making the platelets reactive. The effects of hemodynamic conditions and the agents are known mainly from in vitro ex...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000115608
更新日期:1983-01-01 00:00:00
abstract::Previous findings regarding the role of TNF-alpha-308 gene polymorphism in multiple sclerosis (MS) are contradictory. The aim of this study was to investigate the possible influence of TNF-alpha-308 polymorphism on MS susceptibility and the MS disease process in a Croatian and Slovenian population. Genotyping was perf...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000099159
更新日期:2007-01-01 00:00:00
abstract::In order to consider the prognostic value of hyperdensity of the middle cerebral artery (MCA), we studied retrospectively the medical records of 80 consecutive patients with the diagnosis of ischemic stroke who underwent a non-enhanced computed tomography no longer than 24 h after the onset of the symptoms. To determi...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116949
更新日期:1993-01-01 00:00:00
abstract::A case of Fisher's syndrome associated with trigeminal herpes zoster is reported for the first time. Retrograde propagation of the virus to the brainstem through the trigeminal root was thought to be the most probable pathogenic mechanism. We provide additional evidence suggesting that the focus of Fisher's syndrome i...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115817
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000479003
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral infarction (CI) occurring soon after intracerebral hemorrhage (ICH) has been rarely reported. The purpose of the present study was to characterize this condition and discuss the possible pathophysiology. METHOD:We retrospectively studied 6 patients who developed CI within 10 days after ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000098465
更新日期:2007-01-01 00:00:00
abstract::A 9-year-old girl with huge, double arachnoid cysts at the cerebellopontine angle is reported. After a cyst-peritoneal shunt operation, she developed fine, high-frequency gaze nystagmus towards the lesion side combined with coarse, large amplitude nystagmus in the opposite direction, which is the reverse of the Bruns'...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116903
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000318171
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:We aimed to assess the prevalence of headache and migraine, along with comorbidities, in a large -Saudi sample. METHODS:Self-reported information was collected about headache, migraine and migraine comorbidities including depression, restless legs syndrome (RLS), syncope, bruxism, hypertension and ischaemic...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000487317
更新日期:2018-01-01 00:00:00