Abstract:
:3 out of 24 patients with mitral valve prolapse (MVP), mean age 25.7 +/- 3.1 displayed markedly thickened redundant and shaggy mitral leaflets in the two-dimensional echocardiogram. The anterior leaflet appeared in the parasternal long axis plane club-shaped in diastole. These three female patients had a history of ischemic stroke, which could be verified by CT-scanning. Suggestion is made that MVP and thickening of the valve is correlated with a higher risk for cerebral infarction.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Zenker G,Boné G,Ladurner G,Lechner Hdoi
10.1159/000115766subject
Has Abstractpub_date
1985-01-01 00:00:00pages
82-4issue
1eissn
0014-3022issn
1421-9913journal_volume
24pub_type
杂志文章abstract::The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000075518
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Statins inhibit the production of 2,3-dimethoxy,5-methyl,6-polyisoprene parabenzoquinone also known as ubiquinone or coenzyme Q10 (CoQ10), which is required for mitochondrial electron transport. Idiopathic or primary CoQ10 deficiencies have been known to cause mitochondrial encephalomyopathy. METHODS:We pre...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000101287
更新日期:2007-01-01 00:00:00
abstract::Sixteen children with definite multiple sclerosis (MS; aged 6-17 years, mean 11.4 +/- 2.7; 8 boys, 8 girls) were reviewed. Cerebellar symptoms and signs were frequent at initial presentation. Among laboratory studies, the cerebrospinal fluid (CSF) IgG index or oligoclonal bands were informative in 75%, evoked potentia...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117213
更新日期:1996-01-01 00:00:00
abstract::A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115736
更新日期:1984-01-01 00:00:00
abstract::Median nerve somatosensory evoked potentials (SEPs) and jerk-locked EEG back-averaging (JLA) were performed in 2 patients with left-hand myoclonus. Both SEPs were characterized by a normal parietal N20 and an enhanced N27-P27 fronto-parietal complex, but the giant central N40 described by most authors was only observe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000119509
更新日期:1994-01-01 00:00:00
abstract::While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both star...
journal_title:European neurology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000325733
更新日期:2011-01-01 00:00:00
abstract::The serum concentration of S-100B is reported to reflect the severity of brain damage. The purpose of this study was to determine whether elevated serum S-100B concentrations were related to neuropsychological test performance of patients in the subacute phase of recovery from mild traumatic brain injury (TBI). S-100B...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000083678
更新日期:2005-01-01 00:00:00
abstract::Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms u...
journal_title:European neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000058050
更新日期:2001-01-01 00:00:00
abstract::Reviewing the angiograms of 100 patients with RIA or stroke we found intracranial lesions in 67%, extracranial lesions in 64%, and normal angiograms in 13% of the cases. Risk factors occurred more often as the angiographic lesions were more extensive. These findings confirm the importance of angiographic examination o...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115177
更新日期:1980-01-01 00:00:00
abstract::In order to examine the plasminogen activator (PA) induction involved in the pathogenesis of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS), PA activity in peripheral blood lymphocytes derived from 5 ADEM and 3 MS patients was investigated. There was no PA induction in any ADEM, MS or control ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116971
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Mor...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000456003
更新日期:2017-01-01 00:00:00
abstract::The urinary clearance of pyridostigmine was studied in six patients with myasthenia gravis. In three patients on pyridostigmine alone, renal clearance ranged from 349 to 481 ml/min, corresponding to a pyridostigmine:creatinine clearance ratio of 2.64 to 3.46. In a patient on bendrofluazide as well as pyridostigmine, a...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114882
更新日期:1977-01-01 00:00:00
abstract::70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115267
更新日期:1981-01-01 00:00:00
abstract::We performed serial neurophysiological tests in 22 patients with confirmed Guillain Barré syndrome (GBS) for 12 months following onset of the disease. Twenty-five age- and sex-matched healthy controls were also tested. Tests included nerve conduction and automated quantitative thermal threshold measurements. The commo...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116841
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVES:We attempted to investigate changes of the pedunculopontine nucleus (PPN) according to walking ability in chronic stroke patients, using diffusion tensor imaging (DTI). METHODS:55 consecutive chronic stroke patients who were not able to walk due to injury of the corticospinal tract (CST) at stroke onset and...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000324152
更新日期:2011-01-01 00:00:00
abstract::Missed cerebral aneurysms in CT-negative patients can have serious implications. We set out to determine the usefulness of cerebrospinal fluid (CSF) spectrophotometry and the individual significance of CSF oxyhaemoglobin, bilirubin and methaemoglobin in 463 CT scan-negative patients with suspected subarachnoid haemorr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000082162
更新日期:2004-01-01 00:00:00
abstract::A case of Fisher's syndrome associated with trigeminal herpes zoster is reported for the first time. Retrograde propagation of the virus to the brainstem through the trigeminal root was thought to be the most probable pathogenic mechanism. We provide additional evidence suggesting that the focus of Fisher's syndrome i...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115817
更新日期:1985-01-01 00:00:00
abstract::The frontal lobe is the largest lobe of the brain, and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas. This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkabl...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000117068
更新日期:1994-01-01 00:00:00
abstract::We report a patient who showed exaggerated responses to external cues (utilization behavior), motor impersistence, and a right-hand-predominant instinctive grasp reaction after right thalamic infarction. High-resolution computed tomography with stereotaxic lesion localization revealed almost complete destruction of th...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117092
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:Little is known about optic radiation (OR) injury in intracerebral hemorrhage (ICH). We attempted to investigate OR injury in patients with ICH by diffusion tensor imaging (DTI). METHODS:Forty-three consecutive patients with putaminal hemorrhage and 40 normal healthy control subjects were recruited. DTI dat...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000345271
更新日期:2013-01-01 00:00:00
abstract::In the fast moving field of muscular dystrophy, therapeutic matters are now high on the agenda. Despite little progress made in the understanding of the exact pathogenesis, hopes have been raised with the advent of molecular medicine applied to such disorders. A constellation of techniques or therapeutic solutions are...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000008150
更新日期:2000-01-01 00:00:00
abstract::In a direct (door-to-door) epidemiological study, the prevalence rate of cerebrovascular disease in the rural population of northwest Peloponnese, Greece, was found to be 995 strokes per 100,000 inhabitants over 20 years of age. This number is considerably lower than the prevalence rate (1,417 strokes per 100,000 inha...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116408
更新日期:1989-01-01 00:00:00
abstract::The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114898
更新日期:1977-01-01 00:00:00
abstract::The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000117290
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Thalamic lesion due to deep cerebral venous thrombosis (DCVT) is an uncommon cause of stroke. Until now, only a few case reports have been published. The aim of the study is to report the clinical and radiological findings of thalamic lesion with DCVT. METHODS:We reviewed our computerized stroke database of...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000439167
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:We assessed the, hitherto unknown, impact of intravenous methylprednisolone (ivMP) pulses during relapses of multiple sclerosis (MS) on the kinetics of anti-interferon-beta neutralizing antibodies (Nabs) and binding antibodies (Babs). METHODS:Babs (ELISA) and Nabs (antiviral cytopathic effect assay) ti...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000444319
更新日期:2016-01-01 00:00:00
abstract::Acid phosphatase staining is performed on cerebrospinal fluid cells of 365 samples from 105 patients with various types of meningitis. This enzyme activity is strongly positive in the early samples of bacterial meningitis, as far as the patients had not received a pretreatment with antibiotics for more than 24 h. It a...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116035
更新日期:1986-01-01 00:00:00
abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116350
更新日期:1987-01-01 00:00:00
abstract::Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000113460
更新日期:1997-01-01 00:00:00
abstract::A Norwegian family with asymmetrical scapuloperoneal atrophy is described. Chronic, aching shoulder pain, slight proximal and distal sensory dysfunction, and atrophy of the extensor digitorum brevis muscle occurred in some individuals. The proband had slightly impaired sensory conduction velocity, and his father exhib...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115834
更新日期:1985-01-01 00:00:00