The Development of Sayk's Cell Sedimentation Chamber: A Historical View on Clinical Cerebrospinal Fluid Diagnostics.

Abstract:

OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Moreover, documents in the archives of the Universities of Rostock and Jena, the Brain Research Institute of Cécile and Oskar Vogt in Düsseldorf and the Centre for Neurology at Rostock University were used. RESULTS:The cell sedimentation chamber, developed by Johannes Sayk (1923-2005) at the beginning of the 1950s, enabled, for the first time, CSF cells to be presented with a quality comparable to the blood profile, with a low technological expenditure and using all staining methods suitable for haematological cells. The procedure could be performed quickly and cost efficiently, and therefore, it was easy to integrate it into clinical routine and it quickly became a widely used procedure. In Europe, it was considered the standard method for cytodiagnosis of CSF until the 1990s. CONCLUSIONS:The procedure revolutionised CSF diagnostics and paved the way for modern qualitative CSF cytology. In course of time, the cell sedimentation chamber was superseded by the cytocentrifuge.

journal_name

Eur Neurol

journal_title

European neurology

authors

Dahlmann N,Zettl UK,Kumbier E

doi

10.1159/000456003

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

162-167

issue

3-4

eissn

0014-3022

issn

1421-9913

pii

000456003

journal_volume

77

pub_type

历史文章,杂志文章
  • Positive Predictive Value of French Hospitalization Discharge Codes for Stroke and Transient Ischemic Attack.

    abstract:BACKGROUND:We aimed at measuring the positive predictive value (PPV) of data in the French Hospital Medical Information Database (FHD). SUMMARY:This retrospective multicenter study included 31 hospitals from where 56 hospital stays were randomly selected among all hospitalizations for the years 2009 and 2010 with at l...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000438859

    authors: Giroud M,Hommel M,Benzenine E,Fauconnier J,Béjot Y,Quantin C,FRESCO Study.

    更新日期:2015-01-01 00:00:00

  • Can oral 311C90, a novel 5-HT1D agonist, prevent migraine headache when taken during an aura?

    abstract::The purpose of this pilot study was to determine whether 20 mg oral 311C90 can prevent the development of migraine headache when taken during the aura phase of a migraine attack. The study also aimed to provide an initial safety profile for 311C90 when taken during the aura. Forty patients (31 females, 9 males) were e...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1159/000119101

    authors: Dowson A

    更新日期:1996-01-01 00:00:00

  • Evaluation of the carotid bifurcation by duplex ultrasound, intravenous and intra-arterial digital subtraction angiography.

    abstract::In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116233

    authors: Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

    更新日期:1988-01-01 00:00:00

  • Diagnosis of cerebral venous thrombosis with routine magnetic resonance: an update.

    abstract::Magnetic resonance imaging and angiography is the technique of choice in the diagnosis and follow-up of cerebral venous thrombosis: Thrombosis appears as an absence of flow void on spin echo images and lack of signal in angiographic techniques. The thrombus signal intensity is different on T1 and T2 spin echo weighted...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000007978

    authors: Bianchi D,Maeder P,Bogousslavsky J,Schnyder P,Meuli RA

    更新日期:1998-11-01 00:00:00

  • Diffusion tensor imaging findings of optic radiation in patients with putaminal hemorrhage.

    abstract:OBJECTIVES:Little is known about optic radiation (OR) injury in intracerebral hemorrhage (ICH). We attempted to investigate OR injury in patients with ICH by diffusion tensor imaging (DTI). METHODS:Forty-three consecutive patients with putaminal hemorrhage and 40 normal healthy control subjects were recruited. DTI dat...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000345271

    authors: Seo JP,Choi BY,Chang CH,Jung YJ,Byun WM,Kim SH,Kwon YH,Jang SH

    更新日期:2013-01-01 00:00:00

  • Postganglionic cholinergic dysautonomia: report of muscle findings in 1 case.

    abstract::Heretofore unreported findings in skeletal muscle in a 4th case of pure postganglionic dysautonomia are described. They consist of variation in fiber size, Z line and myofilamentous disorganization, intracytoplasmic inclusions and honeycomb formations. The most striking alterations, however, was excess lipid accumulat...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115448

    authors: Afifi AK,Harik SI,Bergman RA,Mire-Salman J,Bahuth NB

    更新日期:1982-01-01 00:00:00

  • Calcified cerebral hydatid cyst.

    abstract::A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116120

    authors: Micheli F,Lehkuniec E,Giannaula R,Caputi E,Paradiso G

    更新日期:1987-01-01 00:00:00

  • Thalamic infarcts in young adults: relationship between clinical-topographic features and pathogenesis.

    abstract:BACKGROUND:Most reports on thalamic infarcts have focused on clinicoanatomical correlations while the mechanisms of stroke have rarely been investigated. Moreover, most series have included mainly elderly stroke patients, whereas scarce information is available about the etiology of thalamic infarcts in the young. OBJ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000047944

    authors: Pezzini A,Del Zotto E,Archetti S,Albertini A,Gasparotti R,Magoni M,Vignolo LA,Padovani A

    更新日期:2002-01-01 00:00:00

  • Paralysis of upward gaze as a presenting symptom of vitamin B12 deficiency.

    abstract::A 47-year-old woman presented with paralysis of upward gaze associated with Addison's pernicious anaemia. Administration of cyanocobalamin resulted in significant improvement of eye movements and haematological parameters. Isolated paralysis of upward gaze may be a feature of vitamin B12 deficiency. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115702

    authors: Sandyk R

    更新日期:1984-01-01 00:00:00

  • The Pivotal Role of the Parieto-Occipital Lobe in Card Game-Induced Reflex Epilepsy: A Voxel-Based Morphometry Study.

    abstract:BACKGROUND:The pathogenesis of card game-induced reflex epilepsy has not been determined so far. The aim of this study was to evaluate structural abnormalities using voxel-based morphometry (VBM) analysis, which may give some clue about the pathogenesis in card game-induced reflex epilepsy. METHODS:The 3 subjects were...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000447537

    authors: Park KM,Kim SE,Lee BI

    更新日期:2016-01-01 00:00:00

  • Edgar Adrian (1889-1977) and Shell Shock Electrotherapy: A Forgotten History?

    abstract::The English electrophysiologist Edgar Adrian (1889-1977) was the recipient of the Nobel Prize for physiology in 1932 for his research on the functions of neurons. During World War I, at Queen Square in London, he devised an intensive electrotherapeutic treatment for shell-shocked soldiers. The procedure, developed wit...

    journal_title:European neurology

    pub_type: 历史文章,杂志文章

    doi:10.1159/000486762

    authors: Tatu L

    更新日期:2018-01-01 00:00:00

  • Improvement of Orbitofrontal Cortex Function Associated with Blephrospasm Symptom Remission.

    abstract:OBJECTIVE:To determine whether orbitofrontal cortex (OFC) function improves with blepharospasm (BSP) symptom remission using a verbal fluency task and near-infrared spectroscopy (NIRS). METHODS:Nineteen BSP patients and 9 healthy controls (HCs) matched by gender and education were examined using NIRS. The BSP patients...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000471850

    authors: Shen CY,Wang YJ,Liu XM,Zhang XQ,Ren XJ,Ma XY,Sun JJ,Feng K,Sun GX,Xu B,Liu PZ

    更新日期:2017-01-01 00:00:00

  • Spontaneous pain, hyperpathia and wasting of the hand due to parietal lobe haemorrhage.

    abstract::A woman who had spontaneous pain, hyperpathia and wasting of her left hand due to a subcortical lesion in the right parietal lobe is reported. The presentation and evaluation of this most unusual case are discussed. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115753

    authors: Sandyk R

    更新日期:1985-01-01 00:00:00

  • Long-term follow-up EEG studies in patients with traumatic apallic syndrome.

    abstract::The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116316

    authors: Strnad P,Strnadová V

    更新日期:1987-01-01 00:00:00

  • Hypertension with Hyperhomocysteinemia Increases the Risk of Early Cognitive Impairment after First-Ever Ischemic Stroke.

    abstract:BACKGROUND:Hypertension and hyperhomocysteinemia (HHcy) are independent risk factors of stroke and are associated with each other. Although evidence suggests that they are related to cognitive impairment, the relationship between hypertension accompanied with HHcy and poststroke cognitive impairment (PSCI) is unclear. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000504704

    authors: Lu ZH,Li J,Li XL,Ding M,Mao CJ,Zhu XY,Liu CF

    更新日期:2019-01-01 00:00:00

  • Effects of medial temporal atrophy and white matter hyperintensities on the cognitive functions in patients with Alzheimer's disease.

    abstract:AIMS:We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer's disease (AD) patients and the interaction between MTA and WMH. METHODS:From 13 centers, a total of 216 AD patients were consecutivel...

    journal_title:European neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000329277

    authors: Shim YS,Youn YC,Na DL,Kim SY,Cheong HK,Moon SY,Park KW,Ku BD,Lee JY,Jeong JH,Kang H,Kim EJ,Lee JS,Go SM,Kim SH,Cha KR,Seo SW

    更新日期:2011-01-01 00:00:00

  • Adult tuberculous meningitis in Qatar: a descriptive retrospective study from its referral center.

    abstract:BACKGROUND:Tuberculous meningitis is the severest and commonest form of central nervous system tuberculosis causing high mortality and morbidity. We aim to study the clinical, biochemical, and radiological characteristics of tuberculous meningitis in adult patients in Qatar and to calculate the incidence. METHODS:A de...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000368894

    authors: Imam YZ,Ahmedullah HS,Akhtar N,Chacko KC,Kamran S,Al Alousi F,Alsuwaidi Z,Almaslmani M,Al Khal AL,Deleu D

    更新日期:2015-01-01 00:00:00

  • Histological and immunohistological changes of the skeletal muscles in older SJL/J mice.

    abstract::SJL/J mice have been studied as the model animals for autoimmunological diseases. Recently it was clarified that SJL/J mice have a defect of dysferlin. Human limb girdle muscular dystrophy 2B and Miyoshi myopathy also have a defect of dysferlin. In this study we present the histological and immunohistological changes ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000097005

    authors: Nemoto H,Konno S,Nakazora H,Miura H,Kurihara T

    更新日期:2007-01-01 00:00:00

  • Multifocal Motor Neuropathy with Persistent Conduction Block: The Seminal Case.

    abstract::Although multifocal motor neuropathy (MMN) is now recognized as a distinct, albeit rare, neurological condition, the path to its recognition was long and winding. This article provides an insight into the medical history of MMN "patient zero" and the first scientific publication that led to the recognition of MMN by t...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000511732

    authors: Ochsner F,Tatu L

    更新日期:2020-11-11 00:00:00

  • Cerebral venous angioma, cutaneous angioma, facial asymmetry and recurrent stroke. A case report.

    abstract::The case of an 8-year-old boy presenting diffuse, prevalently right-sided nevus flammeus, venous angioma of the right cerebral hemisphere, right-sided facial hyperplasia, lef-handedness and recurring strokes is reported together with the clinical, angiographic and CT features. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115201

    authors: Tomaccini D,Venturi C,Scarfò GB

    更新日期:1981-01-01 00:00:00

  • Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo.

    abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116350

    authors: Nagatsu T,Hirata Y

    更新日期:1987-01-01 00:00:00

  • Highly sensitive troponin T in patients with acute ischemic stroke.

    abstract:BACKGROUND:Newly developed troponin assays have superior diagnostic and prognostic performance in acute coronary syndrome (ACS), when compared to conventional troponin assays; however, highly sensitive troponin has not been evaluated in patients with acute ischemic stroke. METHODS:Highly sensitive troponin T (hsTnT) w...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000341340

    authors: Jensen JK,Ueland T,Aukrust P,Antonsen L,Kristensen SR,Januzzi JL,Ravkilde J

    更新日期:2012-01-01 00:00:00

  • Restless legs syndrome and pregnancy: a questionnaire study in the Poitiers District, France.

    abstract:AIMS:To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy in a European country. METHODS:A cross-sectional questionnaire survey. The questionnaire was distributed by the medical staff in different outpatient waiting rooms (obstetrics and gynecology department of the univ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000321413

    authors: Neau JP,Porcheron A,Mathis S,Julian A,Meurice JC,Paquereau J,Godeneche G,Ciron J,Bouche G

    更新日期:2010-01-01 00:00:00

  • A nation-wide collaborative study on the long-term effects of bromocriptine in patients with Parkinson's disease. First interim report in Japan.

    abstract::Two prospective projects were started in May 1985 to evaluate the long-term effects of bromocriptine in patients with Parkinson's disease. One of the projects is to see if combination therapy with levodopa and bromocriptine is superior to levodopa alone with regard to the prevention of late side effects of levodopa th...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Nakanishi T,Mizuno Y,Goto I,Iwata M,Kanazawa I,Kowa H,Mannen T,Nishitani H,Ogawa N,Takahashi A

    更新日期:1988-01-01 00:00:00

  • Drug-induced headache: long-term follow-up of withdrawal therapy and persistence of drug misuse.

    abstract::Patients suffering from migraine, tension-type headache (TTH), or combined headache (CH) are at risk of developing drug-induced headache (DIH) due to regular use of analgesics, ergot alkaloids, and triptans. The aim of our study was to determine (1) the clinical features of DIH, (2) the outcome of withdrawal therapy u...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000052134

    authors: Fritsche G,Eberl A,Katsarava Z,Limmroth V,Diener HC

    更新日期:2001-01-01 00:00:00

  • Possible regulation of intracranial pressure by human atrial natriuretic peptide in cerebrospinal fluid.

    abstract::To clarify the function of human atrial natriuretic peptide (hANP) in the cerebrospinal fluid (CSF), we examined hANP levels in the CSF of patients with various neurological diseases. The subjects were 16 controls without neurological disease and 45 patients with neurological disease. The 45 patients with neurological...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000113166

    authors: Yamasaki H,Sugino M,Ohsawa N

    更新日期:1997-01-01 00:00:00

  • The myxomatous mitral valve. A risk factor for ischemic stroke in young patients?

    abstract::3 out of 24 patients with mitral valve prolapse (MVP), mean age 25.7 +/- 3.1 displayed markedly thickened redundant and shaggy mitral leaflets in the two-dimensional echocardiogram. The anterior leaflet appeared in the parasternal long axis plane club-shaped in diastole. These three female patients had a history of is...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115766

    authors: Zenker G,Boné G,Ladurner G,Lechner H

    更新日期:1985-01-01 00:00:00

  • Characteristics and outcomes of patients with seizures according to the time of onset in relation to stroke.

    abstract:BACKGROUND/AIM:Although most late-onset seizures (LS) appear within 2 years after stroke, some of them occur later and their characteristics are unknown. The aim of this study was to compare the characteristics of patients with very-late-onset seizures (VLS) to those with early-onset seizures (ES) and those with LS. P...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115635

    authors: De Reuck J,Sieben A,Van Maele G

    更新日期:2008-01-01 00:00:00

  • Brain enzymes and ischemia.

    abstract::Changes in the maximal rate of some cerebral enzymatic activities related to 400ene transduction and neurotransmission (lactate dehydrogenase; citrate synthase and malate dehydrogenase; total NADH-cytochrome c reductase and cytochrome oxidase; glutamate dehydrogenase; acetylcholine esterase) were assayed both in the c...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115242

    authors: Villa RF

    更新日期:1981-01-01 00:00:00

  • The side and somatotopical location of single small infarcts in the corona radiata and pontine base in relation to contralateral limb paresis and dysarthria.

    abstract::The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000117290

    authors: Tohgi H,Takahashi S,Takahashi H,Tamura K,Yonezawa H

    更新日期:1996-01-01 00:00:00