Acid phosphatase activity of cerebrospinal fluid cells in bacterial and abacterial meningitis.

Abstract:

:Acid phosphatase staining is performed on cerebrospinal fluid cells of 365 samples from 105 patients with various types of meningitis. This enzyme activity is strongly positive in the early samples of bacterial meningitis, as far as the patients had not received a pretreatment with antibiotics for more than 24 h. It allows monitoring the response to therapy in subsequent samples. Acid phosphatase activity is positive in 2 cases of cryptococcus meningitis. It is negative in all cases of aseptic and Mycoplasma pneumoniae meningitis. The results in herpes encephalitis are variable, depending on the clinical state and the degree of brain destruction. Acid phosphatase staining is a useful and rapid cytological technique for determination of the nature of the meningitis and for monitoring the therapeutical response.

journal_name

Eur Neurol

journal_title

European neurology

authors

De Reuck JL,De Coster WJ,vander Eecken HM

doi

10.1159/000116035

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

362-8

issue

5

eissn

0014-3022

issn

1421-9913

journal_volume

25

pub_type

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