Age-associated T-lymphocyte activation through mitogens in patients with multiple sclerosis and blood donors.

abstract：:A 21-year-old male developed back pain, fever, and rapidly progressive quadriparesis. Lumbar tap yielded frank pus which was confirmed on magnetic resonance imaging (MRI) to be located mainly in the cervical epidural space. Conservative antibiotic remedy was partially effective for restoration of the neurological defi...

journal_title：European neurology

authors： Fukui T,Ichikawa H,Kawate N,Nozawa T,Sugita K

更新日期：1992-01-01 00:00:00

abstract：:Estrogen receptor (ER) analysis was performed with an enzyme immunoassay using monoclonal antibodies against human ER protein (estrophilin) in 70 meningiomas. [3H]methyltrienolone, a synthetic androgen, was used for concurrent determination of the androgen receptor (AR)-binding activity. Low levels of ER immunoreactiv...

journal_title：European neurology

authors： Lesch KP,Schott W,Engl HG,Gross S

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...

journal_title：European neurology

authors： Brouns R,Sheorajpanday R,Kunnen J,De Surgeloose D,De Deyn PP

更新日期：2009-01-01 00:00:00

abstract：AIM:To determine whether corpus callosum atrophy predicts future clinical deterioration in multiple sclerosis. METHODS:In 39 multiple sclerosis patients the area of corpus callosum in the sagittal plane, T2 and T1 lesion volumes, brain parenchymal fraction and brain atrophy were determined at baseline and 1 year after...

journal_title：European neurology

authors： Vaneckova M,Kalincik T,Krasensky J,Horakova D,Havrdova E,Hrebikova T,Seidl Z

更新日期：2012-01-01 00:00:00

abstract：:The central motor pathways were studied with the technique of percutaneous electrical stimulation of the central nervous system in 40 normal volunteers. There were no significant differences between the right and left sides, or between males and females. A linear correlation between the cortical latency (Lcor) or the ...

journal_title：European neurology

authors： Ugawa Y,Genba K,Shimpo T,Mannen T

更新日期：1989-01-01 00:00:00

abstract：:Cavernomas are vascular malformations mostly observed in the central nervous system. They occur in sporadic and familial forms. Familial forms are characterized by the presence of multiple lesions, an autosomal dominant pattern of inheritance and possible de novo lesions. We report two sporadic cases whose follow-up s...

journal_title：European neurology

authors： Labauge P,Brunereau L,Coubes P,Clanet M,Tannier C,Laberge S,Lévy C

更新日期：2001-01-01 00:00:00

abstract：:Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:Botulinum toxin type B (BT-B) therapy failure due to formation of botulinum toxin type B antibodies (BT-B-AB) has only been reported in patients with botulinum toxin type A antibodies (BT-A-AB). We are reporting BT-B-AB-induced therapy failure in 2 patients with no previous exposure to botulinum toxin. In patient 1 co...

journal_title：European neurology

authors： Dressler D,Bigalke H

更新日期：2004-01-01 00:00:00

abstract：PRIMARY OBJECTIVE:To determine whether the ipsilateral cortex surrounding the lesion or the non-injured contralateral cortex is important for motor recovery after brain damage in the photochemically initiated thrombosis (PIT) model. RESEARCH DESIGN:We induced PIT in the sensorimotor cortex in rats and examined the rec...

journal_title：European neurology

authors： Takata K,Yamauchi H,Tatsuno H,Hashimoto K,Abo M

更新日期：2006-01-01 00:00:00

abstract：:Fifteen chronic alcoholic male patients with impotence have been investigated with the electrophysiological method of sympathetic skin potentials recorded from the genital skin and with the electrically induced bulbocavernosus reflex. Both electrophysiological tests did not differ from those of normal controls. It was...

journal_title：European neurology

authors： Ertekin C,Almis S,Ertekin N

更新日期：1990-01-01 00:00:00

abstract：:Nicorandil, an ATP-sensitive potassium (KATP) channel opener, is known to have protective effects on ischemic injury in heart and brain. One of the most important protective mechanisms is the anti-apoptotic effect on cardiomyocytes and neurons. This study explored the anti-apoptotic effect of nicorandil against neurot...

journal_title：European neurology

authors： Kong J,Ren G,Jia N,Wang Y,Zhang H,Zhang W,Chen B,Cao Y

更新日期：2013-01-01 00:00:00

abstract：:The efficacy and safety of sumatriptan, a selective 5-HT1-like receptor agonist, were studied in a randomized, double-blind, placebo-controlled, parallel-group, multicentre, multinational clinical trial of 235 patients suffering a moderate to severe migraine attack. Patients were randomized to treat a single migraine ...

journal_title：European neurology

authors：

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:We assessed the, hitherto unknown, impact of intravenous methylprednisolone (ivMP) pulses during relapses of multiple sclerosis (MS) on the kinetics of anti-interferon-beta neutralizing antibodies (Nabs) and binding antibodies (Babs). METHODS:Babs (ELISA) and Nabs (antiviral cytopathic effect assay) ti...

journal_title：European neurology

authors： Giantzi V,Karapanayiotides T,Lagoudaki R,Poulatsidou KN,Lourbopoulos A,Daniilidis M,Taskos N,Milonas I,Grigoriadis N

更新日期：2016-01-01 00:00:00

abstract：:In order to quantitatively assess the motor performance characteristics of 14 patients with congenital myotonia, the reaction time, speed of movement, synergy of different muscle groups and accuracy were measured. The Human Performance Measurement/Basic Elements of Performance device was used for recordings. Warned si...

journal_title：European neurology

authors： Baumann P,Vanharanta H,Kauranen K,Myllylä V

更新日期：1995-01-01 00:00:00

abstract：:SJL/J mice have been studied as the model animals for autoimmunological diseases. Recently it was clarified that SJL/J mice have a defect of dysferlin. Human limb girdle muscular dystrophy 2B and Miyoshi myopathy also have a defect of dysferlin. In this study we present the histological and immunohistological changes ...

journal_title：European neurology

authors： Nemoto H,Konno S,Nakazora H,Miura H,Kurihara T

更新日期：2007-01-01 00:00:00

abstract：:Calcium ions play a major role in the regulation of cell functions. Minor alterations of the cellular calcium ion homeostasis lead to major functional aberrations. Alterations of the calcium homeostasis occur under conditions of hypoxia, the major cause being an extracellular increase of potassium ions which gate volt...

journal_title：European neurology

authors： Peters T

更新日期：1986-01-01 00:00:00

abstract：:The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...

journal_title：European neurology

authors： Caspary EA

更新日期：1977-01-01 00:00:00

abstract：:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...

journal_title：European neurology

authors： Terzano MG,Parrino L,Spaggiari MC

更新日期：1990-01-01 00:00:00

abstract：:A catamnestic study of 50 patients with Wernicke's disease showed that nearly all patients retained residual symptoms and that the prognosis as to life expectancy and social functioning was poor, even after early institution of vitamin B-complex medication. It is advisable to give vitamin B-complex prophylactically in...

journal_title：European neurology

authors： Groen RH,Hoff HC

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To assess the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) in patients with clinically isolated syndrome (CIS). METHODS:130 European CIS patients and 60 relatives completed the MSNQ. RESULTS:The mean (SD) MSNQ score for CIS patients was 15.5 (10.8) and for their informants 11.3 (9.6). Neither ...

journal_title：European neurology

authors： Langdon DW,Benedict RH,Wicklein EM,Beckmann K,Fredrikson S

更新日期：2013-01-01 00:00:00

abstract：:Don Quixote de la Mancha, which is considered one of the most important and influential works of Western modern prose, contains many references of interest for almost all of the medical specialties. In this regard, numerous references to neurology can be found in Cervantes' immortal work. In this study, we aimed to re...

journal_title：European neurology

authors： Palma JA,Palma F

更新日期：2012-01-01 00:00:00

abstract：:Bilateral paramedian thalamic infarcts are characterised initially by the association of acute vigilance disorders and vertical gaze palsy, followed by persisting dementia with severe mnemic disturbance, global aspontaneity and apathy. We describe a patient with a dramatic neuropsychological recovery, confirmed by tes...

journal_title：European neurology

authors： Krolak-Salmon P,Croisile B,Houzard C,Setiey A,Girard-Madoux P,Vighetto A

更新日期：2000-01-01 00:00:00

abstract：:Percussion of the skull dates from a time when there were virtually no radiological methods for examining the skull and brain. Three apparently independent contributions appeared within the years 1893-1895. The sound elicited, tenderness, and auscultatory percussion have each been employed for diagnostic purposes, but...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:This study aimed at examining correlations between quantitative REM sleep EEG, regional cerebral blood flow measured by single photon emission computerized tomography (SPECT) and global cognitive functioning in nine patients with mild to moderate Alzheimer's disease. REM sleep EEG was not correlated with SPECT measure...

journal_title：European neurology

authors： Montplaisir J,Petit D,McNamara D,Gauthier S

更新日期：1996-01-01 00:00:00

abstract：:About one third of patients with newly diagnosed epilepsy do not achieve seizure control despite medical therapy and should be assessed in detail to confirm the diagnosis, to determine the epilepsy syndrome and to plan treatment strategy. Refractory epilepsy is established when there is inadequate seizure control desp...

journal_title：European neurology

authors： Beleza P

更新日期：2009-01-01 00:00:00

abstract：:13 patients with spinal dural arteriovenous fistulas (DAVF) diagnosed in our Institution have been the object of this study. The necessity to include the disease in the differential diagnosis with other pathologies affecting the lower thoracic cord, particularly in middle-aged and old males, is emphasized. Involvement...

journal_title：European neurology

authors： Bradac GB,Daniele D,Riva A,Bracchi M,Stura G,Riccio A,Pagni CA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:It is generally assumed that silent brain infarction (SBI) and symptomatic lacunar infarction (sLAC) share common vascular risk factors and their pathogeneses are known to be similar. However, few studies have conducted a risk factor profile analysis of the two diseases in a single study design. METHOD...

journal_title：European neurology

authors： Kim MH,Moon JS,Park SY,An SA,Kim OJ,Kim NK,Oh SH

更新日期：2011-01-01 00:00:00

abstract：:The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...

journal_title：European neurology

authors： Strnad P,Strnadová V

更新日期：1987-01-01 00:00:00

abstract：:The production of novel, motivated or useful material defines creativity, which appears to be one of the higher, specific, human brain functions. While creativity can express itself in virtually any domain, art might particularly well illustrate how creativity may be modulated by the normal or pathological brain. Evid...

journal_title：European neurology

authors： Bogousslavsky J

更新日期：2005-01-01 00:00:00

abstract：:Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

journal_title：European neurology

authors： Lutte I,Laterre C,Bodart JM,De Volder A

更新日期：2000-01-01 00:00:00