Physiologic analysis of central motor pathways--simultaneous recording from multiple relaxed muscles.

abstract：:The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...

journal_title：European neurology

authors： Simuni T,Lyons KE,Pahwa R,Hauser RA,Comella C,Elmer L,Weintraub D

更新日期：2009-01-01 00:00:00

abstract：:We report a 60-year-old right-handed Japanese man who showed an isolated persistent typing impairment without aphasia, agraphia, apraxia or any other neuropsychological deficit. We coined the term 'dystypia' for this peculiar neuropsychological manifestation. The symptom was caused by an infarction in the left frontal...

journal_title：European neurology

authors： Otsuki M,Soma Y,Arihiro S,Watanabe Y,Moriwaki H,Naritomi H

更新日期：2002-01-01 00:00:00

abstract：:Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...

journal_title：European neurology

authors： Hasegawa K,Kowa H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Locked-in syndrome (LIS) is a condition characterized by quadriplegia and anarthria. The most common cause is a ventral pontine lesion due to atherosclerotic basilar artery disease. METHODS:Cases with LIS were prospectively identified among the patients with acute ischemic stroke over 3 years, between 2009 ...

journal_title：European neurology

authors： Nikić PM,Jovanović D,Paspalj D,Georgievski-Brkić B,Savić M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Antioxidant enzymes like copper/zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular diseases and acute stroke. We investigated the differences of antioxi...

journal_title：European neurology

authors： Zimmermann C,Winnefeld K,Streck S,Roskos M,Haberl RL

更新日期：2004-01-01 00:00:00

abstract：:The serum concentration of S-100B is reported to reflect the severity of brain damage. The purpose of this study was to determine whether elevated serum S-100B concentrations were related to neuropsychological test performance of patients in the subacute phase of recovery from mild traumatic brain injury (TBI). S-100B...

journal_title：European neurology

authors： Stapert S,de Kruijk J,Houx P,Menheere P,Twijnstra A,Jolles J

更新日期：2005-01-01 00:00:00

abstract：:QTc intervals were measured in 30 patients with Parkinson's disease and 30 healthy control subjects. The mean value of QTc intervals in patients with Parkinson's disease significantly exceeded that of healthy controls (418 +/- 14 ms vs. 403 +/- 18 ms). Prolongation of the QTc interval was unrelated to the administrati...

journal_title：European neurology

authors： Oka H,Mochio S,Sato H,Katayama K

更新日期：1997-01-01 00:00:00

abstract：:Previous findings regarding the role of TNF-alpha-308 gene polymorphism in multiple sclerosis (MS) are contradictory. The aim of this study was to investigate the possible influence of TNF-alpha-308 polymorphism on MS susceptibility and the MS disease process in a Croatian and Slovenian population. Genotyping was perf...

journal_title：European neurology

authors： Ristić S,Lovrecić L,Starcević-Cizmarević N,Brajenović-Milić B,Sega Jazbec S,Sepcić J,Kapović M,Peterlin B

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to elucidate the influence of insular infarction on blood pressure (BP) variability and outcomes according to the region of the insular cortex affected. METHODS:A total of 90 patients diagnosed with acute unilateral ischemic stroke were registered. The BP variability was calculated...

journal_title：European neurology

authors： Kitamura J,Ueno H,Nagai M,Hosomi N,Honjo K,Nakamori M,Mukai T,Imamura E,Nezu T,Aoki S,Ohshita T,Nomura E,Wakabayashi S,Maruyama H,Matsumoto M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Platelet counts (PCs) <100,000/µl are considered as a contraindication for intravenous thrombolysis (IVT). While US guidelines recommend IVT initiation before the availability of clotting tests, the guidelines of the European Stroke Organization give no such practical advice. We aimed to assess the incidence...

journal_title：European neurology

authors： Breuer L,Huttner HB,Kiphuth IC,Ringwald J,Hilz MJ,Schwab S,Köhrmann M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Several testing options are available to detect asymptomatic coronary artery disease (CAD). Dobutamine stress echocardiography (DSE) has been reported to increase the sensitivity and specificity of stress testing to detect CAD. Most studies concerned patients with known or suspected CAD who have a high prete...

journal_title：European neurology

authors： Nighoghossian N,Cakmak S,Derex L,Barthelet M,Thibault H,Finet G,Ovize M,Derumeaux G,Nemoz C,Chapuis F,Rioufol G

更新日期：2006-01-01 00:00:00

abstract：:Sixteen children with definite multiple sclerosis (MS; aged 6-17 years, mean 11.4 +/- 2.7; 8 boys, 8 girls) were reviewed. Cerebellar symptoms and signs were frequent at initial presentation. Among laboratory studies, the cerebrospinal fluid (CSF) IgG index or oligoclonal bands were informative in 75%, evoked potentia...

journal_title：European neurology

authors： Selcen D,Anlar B,Renda Y

更新日期：1996-01-01 00:00:00

abstract：:The aim of this study was to assess the impact of cardiac autonomic derangement on gender-associated functional outcome of patients with subacute ischemic stroke undergoing a hospital-based rehabilitation program. The study population included 126 consecutive first-ever stroke survivors (mean age 59.7 +/- 11.6 years)....

journal_title：European neurology

authors： Bassi A,Colivicchi F,Santini M,Caltagirone C

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between metabolic syndrome (MetS) and cognitive impairment in elderly patients with white matter lesions (WML). METHODS:From -January 2016 to June 2017, a cross-sectional study was conducted on the clinical data of 358 WML patients over 65 years old in the Department of Neurology ...

journal_title：European neurology

authors： Chen L,Hong W,Yang H,Dong S,Peng Z,Zhou H

更新日期：2019-01-01 00:00:00

abstract：:We report a patient who showed exaggerated responses to external cues (utilization behavior), motor impersistence, and a right-hand-predominant instinctive grasp reaction after right thalamic infarction. High-resolution computed tomography with stereotaxic lesion localization revealed almost complete destruction of th...

journal_title：European neurology

authors： Hashimoto R,Yoshida M,Tanaka Y

更新日期：1995-01-01 00:00:00

abstract：:The objective of this work was to precisely analyse the reduction of the antiparkinsonian treatment in 18 consecutive patients with Parkinson's disease (PD) operated on for bilateral subthalamic nucleus (STN) stimulation, first after 1 month of follow-up, then at 1 year postoperatively. Trihexyphenidyle, selegiline, e...

journal_title：European neurology

authors： Thobois S,Corvaisier S,Mertens P,Di Guardo C,Mollion H,Guenot M,Rochefort F,Chazot G,Sindou M,Broussolle E

更新日期：2003-01-01 00:00:00

abstract：:Increased levels of lactic dehydrogenase (LDH) in cerebrospinal fluid (CSF) have been reported in association with several intracranial pathologies. We studied LDH isoenzymes in the CSF of children with infantile spasms. CSF samples collected from 12 patients (aged 4-9 months) with infantile spasms were analyzed for t...

journal_title：European neurology

authors： Nussinovitch M,Harel D,Eidlitz-Markus T,Amir J,Volovitz B

更新日期：2003-01-01 00:00:00

abstract：INTRODUCTION:Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. METHODS:An in-depth ...

journal_title：European neurology

authors： Xiao Y,Chen MJ,Shen X,Lin LR,Liu LL,Yang TC,Niu JJ

更新日期：2019-01-01 00:00:00

abstract：:Automatic analysis of EMG (T/A analysis) and invasive muscle fiber conduction velocity in situ (MFCV) were performed in 15 patients after traumatic lesions of the knee and immobilization with quadriceps atrophy. T/A analysis showed transient reduced number of turns, consistent with inhibition of quadriceps motoneurons...

journal_title：European neurology

authors： Cruz-Martínez A,Ramírez A,Arpa J

更新日期：2000-01-01 00:00:00

abstract：:Although repetitive transcranial magnetic stimulation (rTMS) for hemiparesis is beneficial, so far no study has examined the usefulness of rTMS for apathy. Thirteen patients with chronic stroke were assigned randomly to 2 groups: rTMS group (n = 7) and sham stimulation group (n = 6). The patients received 5 sessions o...

journal_title：European neurology

authors： Sasaki N,Hara T,Yamada N,Niimi M,Kakuda W,Abo M

更新日期：2017-01-01 00:00:00

abstract：:Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...

journal_title：European neurology

authors： Kaido M,Fujimura H,Ono A,Toyooka K,Yoshikawa H,Nishimura T,Ozaki K,Narama I,Kuwajima M

更新日期：1997-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now documented by several studies. A major breakthrough has been the discovery of two single-gene defects in familial PD. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein gene has been ...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu HC,Lee CC,Tsai CH,Chang JG

更新日期：2000-01-01 00:00:00

abstract：:Changes in the maximal rate of some cerebral enzymatic activities related to 400ene transduction and neurotransmission (lactate dehydrogenase; citrate synthase and malate dehydrogenase; total NADH-cytochrome c reductase and cytochrome oxidase; glutamate dehydrogenase; acetylcholine esterase) were assayed both in the c...

journal_title：European neurology

authors： Villa RF

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Dysnatremia, which is associated with increased mortality in general intensive care units (ICU), has not been thoroughly studied in neurologic ICU (NICU). METHODS:Prevalence of dysnatremia was retrospectively assessed. The multivariable binary logistic regression model was used to determine the influence of...

journal_title：European neurology

authors： Zhang YZ,Qie JY,Zhang QH

更新日期：2015-01-01 00:00:00

abstract：AIM:To assess the safety and clinical efficacy of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with intensive speech therapy (ST) in poststroke patients with aphasia. SUBJECTS AND METHODS:Twenty-four patients with left-hemispheric stroke and aphasia were subjected. During 11-day hospit...

journal_title：European neurology

authors： Abo M,Kakuda W,Watanabe M,Morooka A,Kawakami K,Senoo A

更新日期：2012-01-01 00:00:00

abstract：:A 47-year-old woman presented with paralysis of upward gaze associated with Addison's pernicious anaemia. Administration of cyanocobalamin resulted in significant improvement of eye movements and haematological parameters. Isolated paralysis of upward gaze may be a feature of vitamin B12 deficiency. ...

journal_title：European neurology

authors： Sandyk R

更新日期：1984-01-01 00:00:00

abstract：:Bilateral paramedian thalamic infarcts are characterised initially by the association of acute vigilance disorders and vertical gaze palsy, followed by persisting dementia with severe mnemic disturbance, global aspontaneity and apathy. We describe a patient with a dramatic neuropsychological recovery, confirmed by tes...

journal_title：European neurology

authors： Krolak-Salmon P,Croisile B,Houzard C,Setiey A,Girard-Madoux P,Vighetto A

更新日期：2000-01-01 00:00:00

abstract：:Camptocormia (bent spine syndrome, cyphose hystérique) is an abnormality characterized by severe forward flexion of the thoracolumbar spine which typically increases during walking or standing and completely disappears in supine position. Camptocormia can be due to central nervous system diseases, such as Parkinson's ...

journal_title：European neurology

authors： Finsterer J,Strobl W

更新日期：2010-01-01 00:00:00

abstract：:The effects of biologically active light (BL) on subjective and objective quality of sleep and awakening, as well as circadian rhythms in cortisol, temperature and well-being were studied in 10 hospitalized normal female volunteers as compared with partial sleep deprivation (PSD). After 2 adaption days, three 24-hour ...

journal_title：European neurology

authors： Saletu B,Dietzel M,Lesch OM,Musalek M,Walter H,Grünberger J

更新日期：1986-01-01 00:00:00

abstract：:The aim of this work was to quantify the accumulation of iron in the basal ganglia in multiple sclerosis (MS) patients and in a control group, and to investigate the relationship between iron accumulation and other parameters assessed in MS, i.e. lesion load (LL) and brain parenchymal fraction (BPF). Magnetic resonanc...

journal_title：European neurology

authors： Burgetova A,Seidl Z,Krasensky J,Horakova D,Vaneckova M

更新日期：2010-01-01 00:00:00