Abstract:
BACKGROUND:The aim of this study was to elucidate the influence of insular infarction on blood pressure (BP) variability and outcomes according to the region of the insular cortex affected. METHODS:A total of 90 patients diagnosed with acute unilateral ischemic stroke were registered. The BP variability was calculated over 24 h after admission (hyperacute) and for 2-3 days after admission (acute). Patients were classified into groups of right and left, and then right anterior, right posterior, left anterior, and left posterior insular infarction. RESULTS:Patients with insular infarction showed a significantly larger infarct volume, higher modified Rankin scale scores, and lower SD and coefficient of variation (CV) of -systolic BP in the hyperacute phase than shown by patients without insular infarction (p < 0.01, p < 0.01, p = 0.02, and p = 0.03, respectively). The SD and CV of systolic BP in the hyperacute phase showed significant differences among the 3 groups with right insular infarction, with left insular infarction, and without insular infarction (p < 0.05 and p < 0.05, respectively). There was a tendency for the systolic BP variability to be lower in patients with right anterior insular infarction than in patients with infarcts in other areas. CONCLUSION:The right insular cortex, especially the anterior part, might be a hub for autonomic nervous regulation.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Kitamura J,Ueno H,Nagai M,Hosomi N,Honjo K,Nakamori M,Mukai T,Imamura E,Nezu T,Aoki S,Ohshita T,Nomura E,Wakabayashi S,Maruyama H,Matsumoto Mdoi
10.1159/000486306subject
Has Abstractpub_date
2018-01-01 00:00:00pages
90-99issue
1-2eissn
0014-3022issn
1421-9913pii
000486306journal_volume
79pub_type
杂志文章abstract::QTc intervals were measured in 30 patients with Parkinson's disease and 30 healthy control subjects. The mean value of QTc intervals in patients with Parkinson's disease significantly exceeded that of healthy controls (418 +/- 14 ms vs. 403 +/- 18 ms). Prolongation of the QTc interval was unrelated to the administrati...
journal_title:European neurology
pub_type: 杂志文章
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更新日期:1997-01-01 00:00:00
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journal_title:European neurology
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journal_title:European neurology
pub_type: 杂志文章
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journal_title:European neurology
pub_type: 杂志文章,评审
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更新日期:1987-01-01 00:00:00
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journal_title:European neurology
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journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000116984
更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2000-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
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更新日期:2018-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114721
更新日期:1976-01-01 00:00:00
abstract::A 20-year-old woman with Kearns-Sayre syndrome (KSS) suddenly experienced two episodes of diabetic coma. She was studied to determine whether diabetes mellitus (DM) resulted from insulin resistance or from an insulin secretion abnormality, using the euglycemic glucose clamp technique and the glucagon tolerance test. S...
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pub_type: 杂志文章,评审
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更新日期:1988-01-01 00:00:00
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journal_title:European neurology
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更新日期:1982-01-01 00:00:00
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更新日期:1990-01-01 00:00:00
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更新日期:2019-01-01 00:00:00
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journal_title:European neurology
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00