Autosomal dominant familial Parkinson disease: older onset of age, and good response to levodopa therapy.

Abstract:

:Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the number of neurons of the locus ceruleus was maintained. No Lewy bodies were detected at all from any region where Lewy bodies frequently appear in PD.

journal_name

Eur Neurol

journal_title

European neurology

authors

Hasegawa K,Kowa H

doi

10.1159/000113460

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

39-43

eissn

0014-3022

issn

1421-9913

journal_volume

38 Suppl 1

pub_type

杂志文章
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