Magnetic resonance imaging and neuropathology findings in the goat nervous system following hyperbaric exposures.

Abstract:

:Divers may be at risk of long-term CNS damage from non-symptomatic hyperbaric exposure. We investigated the effect of severe, controlled hyperbaric exposure on a group of healthy goats with similar histories. Thirty goats were exposed to various dive profiles over a period of 5 years, with 17 experiencing decompression sickness (DCS). Brains were scanned using magnetic resonance (MR) imaging techniques. The animals were then culled and grossly examined, with the brain and spinal cord sent for neuropathological examination. No significant correlation was found between age, years diving, DCS or exposure to pressure with MR-detectable lesions in the brain, or with neuropathological lesions in the brain or spinal cord. However, spinal scarring was noted in 3 animals that had suffered from spinal DCS.

journal_name

Eur Neurol

journal_title

European neurology

authors

Blogg SL,Loveman GA,Seddon FM,Woodger N,Koch A,Reuter M,Gennser M,White MG

doi

10.1159/000079254

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

18-28

issue

1

eissn

0014-3022

issn

1421-9913

pii

79254

journal_volume

52

pub_type

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