Lack of association between Leber's hereditary optic neuropathy primary point mutations and multiple sclerosis in Iran.

abstract：:Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...

journal_title：European neurology

authors： Reichmann H,Degoul F,Gold R,Meurers B,Ketelsen UP,Hartmann J,Marsac C,Lestienne P

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...

journal_title：European neurology

authors： Steinhoff BJ,Hartmann R,Luy M,Rombach A,Ziegler G,Schulte-Mönting J,Gilliam FG

更新日期：2010-01-01 00:00:00

abstract：:This lecture is mainly concerned with questions about how hemodynamic conditions in atherosclerotic arteries affect arriving platelets that aggregate there and about the chemical agents responsible for making the platelets reactive. The effects of hemodynamic conditions and the agents are known mainly from in vitro ex...

journal_title：European neurology

authors： Born GV

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...

journal_title：European neurology

authors： Constantinescu I,Korff CM,Vulliemoz S,Picard F,Seeck M

更新日期：2017-01-01 00:00:00

abstract：:Nocturnal sleep patterns were registered from 6 parkinsonian patients treated with bromocryptine, ("-Br-L-ergocryptine, C.B.-154) a dopamine-like agonist. No significant differences in their sleep patterns were found in comparison with patients treated with L-dopa. Since bromocryptine acts direct on the dopaminergic r...

journal_title：European neurology

authors： Rabey J,Vardi J,Glaubman H,Streifler M

更新日期：1978-01-01 00:00:00

abstract：:Automatic analysis of EMG (T/A analysis) and invasive muscle fiber conduction velocity in situ (MFCV) were performed in 15 patients after traumatic lesions of the knee and immobilization with quadriceps atrophy. T/A analysis showed transient reduced number of turns, consistent with inhibition of quadriceps motoneurons...

journal_title：European neurology

authors： Cruz-Martínez A,Ramírez A,Arpa J

更新日期：2000-01-01 00:00:00

abstract：:Clinical evaluation, quantitative analysis of the EMG, and motor unit fiber density were carried out on 34 selected patients that suffered paralytic poliomyelitis. 50% of the subjects developed a late and slowly progressive weakness. Automatic analysis of the electromyogram showed a great increase in mean amplitude in...

journal_title：European neurology

authors： Cruz Martínez A,Pérez Conde MC,Ferrer MT

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Saccade may be abnormal in Parkinson's disease (PD), but there have been no systematic studies on directional asymmetries of horizontal saccades in early PD. The aims of this study were to determine the saccadic abnormalities and their directional asymmetries. METHODS:We recorded visually guided horizontal ...

journal_title：European neurology

authors： Choi SM,Lee SH,Choi KH,Nam TS,Kim JT,Park MS,Kim BC,Kim MK,Cho KH

更新日期：2011-01-01 00:00:00

abstract：:In a direct (door-to-door) epidemiological study, the prevalence rate of cerebrovascular disease in the rural population of northwest Peloponnese, Greece, was found to be 995 strokes per 100,000 inhabitants over 20 years of age. This number is considerably lower than the prevalence rate (1,417 strokes per 100,000 inha...

journal_title：European neurology

authors： Paschalis C,Polychronopoulos P,Makris N,Kondakis X,Papapetropoulos T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Statins inhibit the production of 2,3-dimethoxy,5-methyl,6-polyisoprene parabenzoquinone also known as ubiquinone or coenzyme Q10 (CoQ10), which is required for mitochondrial electron transport. Idiopathic or primary CoQ10 deficiencies have been known to cause mitochondrial encephalomyopathy. METHODS:We pre...

journal_title：European neurology

authors： Thomas JE,Lee N,Thompson PD

更新日期：2007-01-01 00:00:00

abstract：:The aim of this work was to quantify the accumulation of iron in the basal ganglia in multiple sclerosis (MS) patients and in a control group, and to investigate the relationship between iron accumulation and other parameters assessed in MS, i.e. lesion load (LL) and brain parenchymal fraction (BPF). Magnetic resonanc...

journal_title：European neurology

authors： Burgetova A,Seidl Z,Krasensky J,Horakova D,Vaneckova M

更新日期：2010-01-01 00:00:00

abstract：:The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...

journal_title：European neurology

authors： Simuni T,Lyons KE,Pahwa R,Hauser RA,Comella C,Elmer L,Weintraub D

更新日期：2009-01-01 00:00:00

abstract：:The effect of oral treatment with acyclovir (ACV) on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia (PHN) was studied in 105 patients with herpes zoster. Forty-seven patients were treated with ACV at a dose of 4 g/day in 5 doses for at least a week; the others did not undergo any kind of...

journal_title：European neurology

authors： Mondelli M,Romano C,Passero S,Porta PD,Rossi A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Large cavitary lesions are not typical for multiple sclerosis (MS). Cavitary white matter changes may be seen in megalencephalic leukoencephalopathy with subcortical cysts, Alexander disease, mitochondrial leukoencephalopathies, vanishing white matter disease, leukoencephalopathy with calcifications and cyst...

journal_title：European neurology

authors： Renard D,Brochet B,Vukusic S,Edan G,Deburghgraeve V,Goizet C,Dupuy D,Touze E,Deschamps R,Zephyr H,Creange A,Castelnovo G,Boespflug-Tanguy O,Labauge P

更新日期：2012-01-01 00:00:00

abstract：:Although many studies have been performed on nervous tissue pathology in Guillain-Barré syndrome (GBS), much less is known about pathological changes in skeletal muscle in this disorder. We have studied muscle biopsies from 5 patients with GBS, 5 patients with amyotrophic lateral sclerosis (control A), and 5 patients ...

journal_title：European neurology

authors： Ono S,Inoue K,Munakata S,Nagao K,Shimizu N

更新日期：1998-01-01 00:00:00

abstract：:Dopamine uptake sites, labelled by 3 nM [3H]GBR 12935, were reduced by 28-34% in post-mortem Parkinson's diseased striata (n = 22) compared to control striata (n = 28). There was no significant difference between post-mortem striata from schizophrenics (n = 16) and controls. Both dopamine D1 and D2 receptors are consi...

journal_title：European neurology

authors： Pearce RK,Seeman P,Jellinger K,Tourtellotte WW

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Mor...

journal_title：European neurology

authors： Dahlmann N,Zettl UK,Kumbier E

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To assess the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) in patients with clinically isolated syndrome (CIS). METHODS:130 European CIS patients and 60 relatives completed the MSNQ. RESULTS:The mean (SD) MSNQ score for CIS patients was 15.5 (10.8) and for their informants 11.3 (9.6). Neither ...

journal_title：European neurology

authors： Langdon DW,Benedict RH,Wicklein EM,Beckmann K,Fredrikson S

更新日期：2013-01-01 00:00:00

abstract：:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...

journal_title：European neurology

authors： Terzano MG,Parrino L,Spaggiari MC

更新日期：1990-01-01 00:00:00

abstract：:We wish to retract the paper entitled "Hypovitaminosis D and Decreased Bone Mineral Density in Amyotrophic Lateral Sclerosis" [Eur Neurol 1997; 37: 225-229] by Y. Sato, Y. Honda, T. Asoh, M. Kikuyama, K. Oizumi as a -result of concerns about data integrity and scientific misconduct which have been brought to our atten...

journal_title：European neurology

authors：

更新日期：2018-01-01 00:00:00

abstract：:In a 5-year follow-up of a case of adult metachromatic leukodystrophy, already diagnosed in the preclinical stage, the development of the symptoms of this disease could be studied in detail: initially, lack of drive, emotional lability and depressive mood. At the same time, pain in the arms and beginning gait disturba...

journal_title：European neurology

authors： Pilz H,Duensing I,Heipertz R,Seidel D,Lowitzsch K,Hopf HC,Goebel HH

更新日期：1977-01-01 00:00:00

abstract：:There is good evidence that patients with Parkinson's disease have respiratory chain dysfunction in their substantia nigra. Since mitochondrial cytopathies due to enzyme defects in the respiratory chain are predominantly manifested in tissues with a high oxidative metabolism we analyzed oxidative energy metabolism in ...

journal_title：European neurology

authors： Reichmann H,Janetzky B,Bischof F,Seibel P,Schöls L,Kuhn W,Przuntek H

更新日期：1994-01-01 00:00:00

abstract：:Temporal arteritis (TA) is a vasculitis involving mainly cranial branches of the aorta that can lead to ischemic complications such as amaurosis or ischemic stroke. Increment in the platelet count has been described in the acute period of the disease. We studied retrospectively the platelet count in patients with TA, ...

journal_title：European neurology

authors： Gonzalez-Alegre P,Ruiz-Lopez AD,Abarca-Costalago M,Gonzalez-Santos P

更新日期：2001-01-01 00:00:00

abstract：:A double-blind controlled trial was performed on 6 patients affected with Steinert's disease in order to evaluate the efficacy of two different dosages of diphenylhydantoin (PHT, 200 and 300 mg/day) and carbamazepine (CBZ, 600 and 800 mg/day) on the myotonic afterdischarge. Both dosages of PHT and CBZ induced a signif...

journal_title：European neurology

authors： Sechi GP,Traccis S,Durelli L,Monaco F,Mutani R

更新日期：1983-01-01 00:00:00

abstract：:Embolism from the aneurysmal sac is a rare but possible manifestation of intracranial aneurysm; thrombus formation is probably related to the combined action of turbulent flow and a 'stagnant zone'. Three cases are presented: 2 with giant aneurysms (1 internal carotid and 1 sylvian) and 1 with a large aneurysm of the ...

journal_title：European neurology

authors： Parenti G,Fiori L,Marconi F

更新日期：1992-01-01 00:00:00

abstract：:Calcium ions play a major role in the regulation of cell functions. Minor alterations of the cellular calcium ion homeostasis lead to major functional aberrations. Alterations of the calcium homeostasis occur under conditions of hypoxia, the major cause being an extracellular increase of potassium ions which gate volt...

journal_title：European neurology

authors： Peters T

更新日期：1986-01-01 00:00:00

abstract：:We report a patient who showed exaggerated responses to external cues (utilization behavior), motor impersistence, and a right-hand-predominant instinctive grasp reaction after right thalamic infarction. High-resolution computed tomography with stereotaxic lesion localization revealed almost complete destruction of th...

journal_title：European neurology

authors： Hashimoto R,Yoshida M,Tanaka Y

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...

journal_title：European neurology

authors： Hao Z,Wu B,Lin S,Kong FY,Tao WD,Wang DR,Liu M

更新日期：2010-01-01 00:00:00

abstract：:The blink reflex and its equivalent glabella tap reflex are behavioural motor responses normally found in neonates and in the physiological startle reflex. Historically, it was described by Overend in 1896 and soon afterwards by McCarthy and by Bekhterev who disputed its origins. Kugelberg in 1952 recorded the early-l...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00