Myoglobin RIA in detecting carriers of Duchenne's muscular dystrophy.

abstract：:The aim of this work was to quantify the accumulation of iron in the basal ganglia in multiple sclerosis (MS) patients and in a control group, and to investigate the relationship between iron accumulation and other parameters assessed in MS, i.e. lesion load (LL) and brain parenchymal fraction (BPF). Magnetic resonanc...

journal_title：European neurology

authors： Burgetova A,Seidl Z,Krasensky J,Horakova D,Vaneckova M

更新日期：2010-01-01 00:00:00

abstract：:Heretofore unreported findings in skeletal muscle in a 4th case of pure postganglionic dysautonomia are described. They consist of variation in fiber size, Z line and myofilamentous disorganization, intracytoplasmic inclusions and honeycomb formations. The most striking alterations, however, was excess lipid accumulat...

journal_title：European neurology

authors： Afifi AK,Harik SI,Bergman RA,Mire-Salman J,Bahuth NB

更新日期：1982-01-01 00:00:00

abstract：:The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...

journal_title：European neurology

authors： Houshmand M,Sanati MH,Rashedi I,Sharifpanah F,Asghari E,Lotfi J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Patients with multiple sclerosis (MS) report sleep disturbances (SD) and excessive daytime sleepiness (EDS) more frequently than the general population. Our objectives were to evaluate SD and EDS in MS patients and to test the reliability of subjective sleep questionnaires. METHODS:Demographic and clinical ...

journal_title：European neurology

authors： Neau JP,Paquereau J,Auche V,Mathis S,Godeneche G,Ciron J,Moinot N,Bouche G

更新日期：2012-01-01 00:00:00

abstract：:The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...

journal_title：European neurology

authors： Caspary EA

更新日期：1977-01-01 00:00:00

abstract：:The gradual intraneuronal accumulation of an insoluble fibrous material which partly consists of abnormally phosphorylated tau protein (neurofibrillary change) represents an important neuropathological hallmark of Alzheimer's disease. Neurofibrillary tangles and neuropil threads formed from this material develop in on...

journal_title：European neurology

authors： Braak H,Braak E,Bohl J

更新日期：1993-01-01 00:00:00

abstract：:Positron emission tomography (PET) has opened new fields of investigation on clinicometabolic correlations in subcortical infarcts. Functional changes occurring in structurally unaffected brain regions represent one of the most interesting aspects of PET application. So far, the only one PET study on lacunar infarcts ...

journal_title：European neurology

authors： Di Piero V,Lenzi GL,Fieschi C

更新日期：1989-01-01 00:00:00

abstract：:A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...

journal_title：European neurology

authors： Micheli F,Lehkuniec E,Giannaula R,Caputi E,Paradiso G

更新日期：1987-01-01 00:00:00

abstract：:About one third of patients with newly diagnosed epilepsy do not achieve seizure control despite medical therapy and should be assessed in detail to confirm the diagnosis, to determine the epilepsy syndrome and to plan treatment strategy. Refractory epilepsy is established when there is inadequate seizure control desp...

journal_title：European neurology

authors： Beleza P

更新日期：2009-01-01 00:00:00

abstract：:Henri Duret (1849-1921) was a surgeon whose training started in the laboratory of Jean-Martin Charcot and Alfred Vulpian at La Salpêtrière in 1874. Using injections of colored gelatine, Duret was the first to describe the distribution of supply arteries in the brainstem and then in the cortex. His descriptions correla...

journal_title：European neurology

authors： Walusinski O,Courrivaud P

更新日期：2014-01-01 00:00:00

abstract：:The serum concentration of S-100B is reported to reflect the severity of brain damage. The purpose of this study was to determine whether elevated serum S-100B concentrations were related to neuropsychological test performance of patients in the subacute phase of recovery from mild traumatic brain injury (TBI). S-100B...

journal_title：European neurology

authors： Stapert S,de Kruijk J,Houx P,Menheere P,Twijnstra A,Jolles J

更新日期：2005-01-01 00:00:00

abstract：:The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...

journal_title：European neurology

authors： Cardaioli G,Di Filippo M,Bianchi A,Eusebi P,Di Gregorio M,Gaetani L,Gallina A,Calabresi P,Sarchielli P

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although ataxic hemiparesis is a common lacunar syndrome, the precise mechanism underlying hemiataxia is not clear. We attempted to identify ataxia-related, cerebral blood flow changes in patients presenting with ataxic hemiparesis after acute capsular infarct. METHODS:We used 99mTc-ECD brain pe...

journal_title：European neurology

authors： Yamamoto R,Johkura K,Nakae Y,Tanaka F

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...

journal_title：European neurology

authors： Tohgi H,Takahashi S,Takahashi H,Tamura K,Yonezawa H

更新日期：1996-01-01 00:00:00

abstract：:Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...

journal_title：European neurology

authors： Hanihara T,Amano N,Takahashi T,Itoh Y,Yagishita S

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The profile and degree of cognitive impairment in Multiple System Atrophy (MSA) and the impact of sleep disorders, REM sleep behavior disorder (RBD) in particular, in parkinsonism-related cognitive deficits are currently being debated. SUMMARY:We reviewed the cognitive, affective and sleep findings in MSA a...

journal_title：European neurology

authors： Stanzani-Maserati M,Gallassi R,Calandra-Buonaura G,Alessandria M,Oppi F,Poda R,Sambati L,Provini F,Cortelli P

更新日期：2014-01-01 00:00:00

abstract：:Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

journal_title：European neurology

authors： Lutte I,Laterre C,Bodart JM,De Volder A

更新日期：2000-01-01 00:00:00

abstract：:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...

journal_title：European neurology

authors： Terzano MG,Parrino L,Spaggiari MC

更新日期：1990-01-01 00:00:00

abstract：:Changes in the maximal rate of some cerebral enzymatic activities related to 400ene transduction and neurotransmission (lactate dehydrogenase; citrate synthase and malate dehydrogenase; total NADH-cytochrome c reductase and cytochrome oxidase; glutamate dehydrogenase; acetylcholine esterase) were assayed both in the c...

journal_title：European neurology

authors： Villa RF

更新日期：1981-01-01 00:00:00

abstract：:Two cases are presented with a long clinical history of multiple sclerosis (MS) before the diagnosis of an intracranial brain tumor. In the subsequent brain autopsy, however, both cases presented a diffusely growing anaplastic astrocytoma, only, and no changes similar to MS were seen. Diffuse tumor growth was noted in...

journal_title：European neurology

authors： Röyttä M,Latvala M

更新日期：1986-01-01 00:00:00

abstract：:The biochemical process underlying Parkinson's disease is dopamine cell death of the nigrostriatal system. The age-dependent cell death is now proposed to be elicited by the formation of free hydroxy radicals which are formed from hydrogen peroxide, a product of oxidation of dopamine by monoamine oxidase, especially t...

journal_title：European neurology

authors： Naoi M,Maruyama W

更新日期：1993-01-01 00:00:00

abstract：:Reviewing the angiograms of 100 patients with RIA or stroke we found intracranial lesions in 67%, extracranial lesions in 64%, and normal angiograms in 13% of the cases. Risk factors occurred more often as the angiographic lesions were more extensive. These findings confirm the importance of angiographic examination o...

journal_title：European neurology

authors： van Oudenaarden WF,Tans JT,Hoogland PH

更新日期：1980-01-01 00:00:00

abstract：:Dopamine uptake sites, labelled by 3 nM [3H]GBR 12935, were reduced by 28-34% in post-mortem Parkinson's diseased striata (n = 22) compared to control striata (n = 28). There was no significant difference between post-mortem striata from schizophrenics (n = 16) and controls. Both dopamine D1 and D2 receptors are consi...

journal_title：European neurology

authors： Pearce RK,Seeman P,Jellinger K,Tourtellotte WW

更新日期：1990-01-01 00:00:00

abstract：BACKGROUNDS:It is often difficult to diagnose stroke subtypes at admission, particularly in sinus rhythm cases. Vascular pedicle width (VPW) on chest X-ray (CXR) and maximal P-wave duration (P-max) on electrocardiogram (ECG) are again realized as useful parameters reflecting intravascular volume and atrial conduction s...

journal_title：European neurology

authors： Sugie M,Kamiya Y,Iizuka N,Murakami H,Kawamura M,Ichikawa H

更新日期：2015-01-01 00:00:00

abstract：:Although many studies have been performed on nervous tissue pathology in Guillain-Barré syndrome (GBS), much less is known about pathological changes in skeletal muscle in this disorder. We have studied muscle biopsies from 5 patients with GBS, 5 patients with amyotrophic lateral sclerosis (control A), and 5 patients ...

journal_title：European neurology

authors： Ono S,Inoue K,Munakata S,Nagao K,Shimizu N

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS:Conse...

journal_title：European neurology

authors： Kim SJ,Noh HJ,Yoon CW,Kim KH,Jeon P,Bang OY,Kim GM,Chung CS,Lee KH

更新日期：2012-01-01 00:00:00

abstract：:Continuing the previously published clinical development of a case of adult metachromatic leukodystrophy (MLD), we now describe the terminal phase and death (at 46 years of age) of our patient. The final phase was characterized clinically by progression of generalized peripheral neuropathy, advanced extrapyramidal and...

journal_title：European neurology

authors： Seidel D,Heipertz R,Goebel HH,Duensing I,Pilz H

更新日期：1980-01-01 00:00:00

abstract：:40 patients with multiple sclerosis were investigated by magnetic resonance imaging (MRI) and computer tomography (CT). Additionally, cerebrospinal fluid (CSF) findings and evoked potentials (EPs; visual, brainstem) were evaluated. MRI findings were abnormal in 85% of the patients, whilst CT scan showed pathological c...

journal_title：European neurology

authors： Boné G,Ladurner G,Artmann W,Bsteh C

更新日期：1988-01-01 00:00:00

abstract：:The cerebral hemispheres show prominent involvement in hypertensive encephalopathy far more frequently than the brainstem. Two patients with severe paroxysmally accelerated hypertension associated with brainstem hyperintensity in T2-weighted magnetic resonance images are presented. Both present hyperintense lesions im...

journal_title：European neurology

authors： Uchino M,Haga D,Nomoto J,Mito T,Kuramitsu T

更新日期：2007-01-01 00:00:00

abstract：:We have recently observed a diffuse slowing of brain waves using serial quantitative electroencephalographic (qEEG) examinations in interferon (IFN)-alpha-treated chronic hepatitis C patients. However, it remains unclear how this alteration could be assessed. We evaluated the correlation between the qEEG changes and t...

journal_title：European neurology

authors： Kamei S,Sakai T,Matsuura M,Tanaka N,Kojima T,Arakawa Y,Matsukawa Y,Mizutani T,Oga K,Ohkubo H,Matsumura H,Hirayanagi K

更新日期：2002-01-01 00:00:00