Abstract:
BACKGROUND AND PURPOSE:Although ataxic hemiparesis is a common lacunar syndrome, the precise mechanism underlying hemiataxia is not clear. We attempted to identify ataxia-related, cerebral blood flow changes in patients presenting with ataxic hemiparesis after acute capsular infarct. METHODS:We used 99mTc-ECD brain perfusion single-photon emission computed tomography to evaluate regional cerebral blood flow in 12 patients with ataxic hemiparesis caused by capsular infarct, and we compared the regional blood flow of these patients with that of 11 patients with pure motor hemiparesis caused by similar lesions. RESULTS:The ipsilateral red nucleus blood flow was significantly decreased in the ataxic hemiparesis patients, whereas the ipsilateral red nucleus blood flow was increased in the pure motor hemiparesis patients. Crossed cerebellar diaschisis (decreased contralateral cerebellar blood flow) was seen in ataxic hemiparesis patients; similarly, it was seen in pure motor hemiparesis patients. CONCLUSIONS:Our findings suggest that ataxia in hemiparetic patients with capsular infarct can be caused by ipsilateral red nucleus dysfunction secondary to cortico-rubral pathway disruption at the internal capsule.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Yamamoto R,Johkura K,Nakae Y,Tanaka Fdoi
10.1159/000369009subject
Has Abstractpub_date
2015-01-01 00:00:00pages
106-11issue
1-2eissn
0014-3022issn
1421-9913pii
000369009journal_volume
73pub_type
杂志文章abstract::Diplopia, blurred vision and colour disturbances are well-known side effects associated with anti-epileptic drugs (AEDs). Farnsworth-Munsell 100-hue colour test (F-100) is an accepted and sensitive tool to detect changes in colour perception. To determine the impact of AEDs upon colour vision, we evaluated 37 consecut...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008051
更新日期:1999-01-01 00:00:00
abstract::There is good evidence that patients with Parkinson's disease have respiratory chain dysfunction in their substantia nigra. Since mitochondrial cytopathies due to enzyme defects in the respiratory chain are predominantly manifested in tissues with a high oxidative metabolism we analyzed oxidative energy metabolism in ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117053
更新日期:1994-01-01 00:00:00
abstract::The child prodigy Marie-Jean-Pierre Flourens received his medical degree at Montpellier when aged 19. As a young promising physician Flourens was asked to investigate Gall's controversial views on cerebral localization. To test Gall's assertions, Flourens developed ablation as a procedure to explore the workings of th...
journal_title:European neurology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000206858
更新日期:2009-01-01 00:00:00
abstract::A 48-year-old woman was referred from Zaire with suspected rabies encephalitis. Survival was 34 days after the onset of symptoms and the diagnosis of rabies was ultimately proven after brain autopsy. Serial neurophysiological investigations, including EEG and multimodality evoked potentials and radiological examinatio...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116939
更新日期:1993-01-01 00:00:00
abstract::Nocturnal sleep patterns were registered from 6 parkinsonian patients treated with bromocryptine, ("-Br-L-ergocryptine, C.B.-154) a dopamine-like agonist. No significant differences in their sleep patterns were found in comparison with patients treated with L-dopa. Since bromocryptine acts direct on the dopaminergic r...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114973
更新日期:1978-01-01 00:00:00
abstract::Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117353
更新日期:1990-01-01 00:00:00
abstract::Botulinum toxin type B (BT-B) therapy failure due to formation of botulinum toxin type B antibodies (BT-B-AB) has only been reported in patients with botulinum toxin type A antibodies (BT-A-AB). We are reporting BT-B-AB-induced therapy failure in 2 patients with no previous exposure to botulinum toxin. In patient 1 co...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000081463
更新日期:2004-01-01 00:00:00
abstract::Embolism from the aneurysmal sac is a rare but possible manifestation of intracranial aneurysm; thrombus formation is probably related to the combined action of turbulent flow and a 'stagnant zone'. Three cases are presented: 2 with giant aneurysms (1 internal carotid and 1 sylvian) and 1 with a large aneurysm of the ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116824
更新日期:1992-01-01 00:00:00
abstract::Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008187
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000479003
更新日期:2017-01-01 00:00:00
abstract::The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115534
更新日期:1983-01-01 00:00:00
abstract::Bilateral paramedian thalamic infarcts are characterised initially by the association of acute vigilance disorders and vertical gaze palsy, followed by persisting dementia with severe mnemic disturbance, global aspontaneity and apathy. We describe a patient with a dramatic neuropsychological recovery, confirmed by tes...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008239
更新日期:2000-01-01 00:00:00
abstract::An 18-year-old mongoloid girl (trisomy 21) of Asian descent presented two symptoms rarely associated with mongolism (Down's syndrome). (1) Brain stem calcification; the first case diagnosed in vivo in mongolism on computerized axial tomography. (2) Hallucinatory psychotic depression; the first case successfully treate...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114963
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Mood disorder is a frequent complication of stroke. Comorbid depressive and anxiety disorders are very common, indicating that it is advisable to assess both disorders at the same time. The aim of the present study was to examine the prevalence of post-stroke depression (PSD) and poststroke anxiety (PSA) at ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000332585
更新日期:2011-01-01 00:00:00
abstract::Local cerebral glucose utilization (LCGU) was determined in 2- to 8-day-old beagle dogs by the quantitative 14C-deoxyglucose autoradiographic method. In physiologically controlled puppies (BP 66 +/- 3 mm Hg; paO2 71 +/- 2 mm Hg; paCO2 35 mm Hg, pH 7.39 +/- 0.04; hematocrit 39 +/- 2%), the 2-deoxyglucose (2-DG) autorad...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115226
更新日期:1981-01-01 00:00:00
abstract::The effect of phytohemagglutinin (PHA) and pokeweed mitogen (PWM) on blood lymphocytes was studied in multiple sclerosis, patients with acute CNS infections, and healthy controls. No significant differences in lymphocyte proliferation were registered between the group of MS patients and the two other groups, irrespect...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115075
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000285165
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Tuberculous meningitis is the severest and commonest form of central nervous system tuberculosis causing high mortality and morbidity. We aim to study the clinical, biochemical, and radiological characteristics of tuberculous meningitis in adult patients in Qatar and to calculate the incidence. METHODS:A de...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000368894
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000050752
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Cerebral arteriovenous malformations (AVMs) harbor a network of abnormal vasculatures, namely the nidus between arterial and venous components. The pressure gradient between these two components results in abnormal high-velocity arteriovenous shunts flowing through the nidus and alternate intracranial hemody...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000292431
更新日期:2010-01-01 00:00:00
abstract::In this open study patients with advanced Parkinson's disease, who experienced pronounced fluctuations in symptoms while on standard L-dopa, were switched from Madopar/Sinemet to Madopar HBS. The dosage was adjusted until optimal response was obtained. The effect was unsatisfactory in 4 cases and side effects interven...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116195
更新日期:1987-01-01 00:00:00
abstract::Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000113460
更新日期:1997-01-01 00:00:00
abstract::The authors report a case of a giant aneurysm of the distal portion of the posterior inferior cerebellar artery presenting the classical picture of a tumor of the posterior fossa. CT scan of a giant aneurysm reveals the clear margin and high density area of aneurysm wall, and the homogeneous and high density area of t...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115108
更新日期:1979-01-01 00:00:00
abstract::Seventy-eight asymptomatic HIV-seropositive (aHIV) subjects were examined by means of an extensive neuropsychological test battery in comparison with 32 HIV-seronegative controls. They were also tested with regard to CD4+ and serum p24 antigen. Fifty-six of them completed a clinical follow-up of 12 up to 36 months and...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117228
更新日期:1996-01-01 00:00:00
abstract::The association of anaemia and gastro-intestinal abnormalities with disorders of the brain, spinal cord, and peripheral nerves has been recognized since the mid 19th century. In early reports interpretable as subacute combined degeneration, anaemia was overlooked, and conversely in Addison's and other early reports of...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000131715
更新日期:2008-01-01 00:00:00
abstract::A case of peripheral neuropathy due to styrene is described. The diagnosis of peripheral neuropathy was confirmed by a motor-nerve conduction study and sural nerve biopsy. ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116046
更新日期:1986-01-01 00:00:00
abstract::A critical analysis of cases of systemic lupus erythematosus (SLE) and chorea is presented. Choreatic movements occurred early in the course of the disease in most cases; the duration varied from several days to 3 years. No sex predominance was found and no relationship could be demonstrated between chorea and other n...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115743
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease. METHODS:One hundred and thirty-three women with...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000165349
更新日期:2009-01-01 00:00:00
abstract::20 patients who had clinical symptoms and/or signs of compression of the 7th and/or 6th cervical roots were examined. Motor and sensory nerve conduction velocities, velocities in the proximal segment of the median nerve determined by measuring F-wave latencies, cervical somatosensory evoked potentials, and needle elec...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115592
更新日期:1983-01-01 00:00:00
abstract::Concentrations of carbamazepine (CBZ) and its metabolite carbamazepine-10, 11-epoxide (CE) were determined in serum (free and total), brain tumors and paratumorous cortex from 37 epileptic patients. Tumor biopsies were available from 25 different gliomas, 5 hamartomas and 1 angioma. The free serum concentrations of CB...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117041
更新日期:1994-01-01 00:00:00