Unaltered respiratory chain enzyme activity and mitochondrial DNA in skeletal muscle from patients with idiopathic Parkinson's syndrome.

abstract：:The importance of patent foramen ovale (PFO) has long been discussed in the literature in relation to different coexisting medical conditions. Many researchers focused on the occurrence of PFO in ischemic stroke patients, especially in the subgroup of young patients with a recurrent event. Unfortunately, before establ...

journal_title：European neurology

authors： Piechowski-Jozwiak B,Bogousslavsky J

更新日期：2013-01-01 00:00:00

abstract：:Although multifocal motor neuropathy (MMN) is now recognized as a distinct, albeit rare, neurological condition, the path to its recognition was long and winding. This article provides an insight into the medical history of MMN "patient zero" and the first scientific publication that led to the recognition of MMN by t...

journal_title：European neurology

authors： Ochsner F,Tatu L

更新日期：2020-11-11 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now documented by several studies. A major breakthrough has been the discovery of two single-gene defects in familial PD. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein gene has been ...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu HC,Lee CC,Tsai CH,Chang JG

更新日期：2000-01-01 00:00:00

abstract：AIM:To determine the frequency of epilepsies in the family members of epileptic patients. METHODS:The records of 4,851 patients with epilepsy were reviewed. The frequency and patterns of different epilepsies and epileptic syndromes in the patients, number of affected relatives and consanguinity were studied. RESULTS:...

journal_title：European neurology

authors： Sozmen V,Baybas S,Dirican A,Koksal A,Ozturk M

更新日期：2011-01-01 00:00:00

abstract：:The effect of dosage schedules on plasma drug levels was evaluated in two groups of ambulant epileptic patients, whose treatment with diphenylhydantoin (DPH) or phenobarbital (PB) had been simplified by reducing the daily frequency of the dosage regimens. Although the patients received the same milligram per kilogram ...

journal_title：European neurology

authors： Zaccara G,Galli A

更新日期：1979-01-01 00:00:00

abstract：:Two cases of malignant tumours of the nerve sheaths are reported. In the first patient, who had von Recklinghausen's disease, light- and electron-microscopic investigations showed an undifferentiated mesenchymal tumour of the radial nerve with the property of producing collagen fibres, an aspect characteristic of sarc...

journal_title：European neurology

authors： Vuia O

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although ataxic hemiparesis is a common lacunar syndrome, the precise mechanism underlying hemiataxia is not clear. We attempted to identify ataxia-related, cerebral blood flow changes in patients presenting with ataxic hemiparesis after acute capsular infarct. METHODS:We used 99mTc-ECD brain pe...

journal_title：European neurology

authors： Yamamoto R,Johkura K,Nakae Y,Tanaka F

更新日期：2015-01-01 00:00:00

abstract：:Two cases of lithium neurotoxic effects are reported. Both cases are expressed by choreoathetotic movements and in both of them intoxication was caused by combined drug therapy. In our opinion caution is advised when lithium is administered in combination with drugs, especially in elderly patients. ...

journal_title：European neurology

authors： Walevski A,Radwan M

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:We assessed the, hitherto unknown, impact of intravenous methylprednisolone (ivMP) pulses during relapses of multiple sclerosis (MS) on the kinetics of anti-interferon-beta neutralizing antibodies (Nabs) and binding antibodies (Babs). METHODS:Babs (ELISA) and Nabs (antiviral cytopathic effect assay) ti...

journal_title：European neurology

authors： Giantzi V,Karapanayiotides T,Lagoudaki R,Poulatsidou KN,Lourbopoulos A,Daniilidis M,Taskos N,Milonas I,Grigoriadis N

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:To examine the therapeutic effect of intravenous recombinant tissue plasminogen activator (rt-PA) therapy for stroke patients receiving maintenance hemodialysis (HD). methods: Of 600 stroke patients receiving intravenous rt-PA using 0.6 mg/kg alteplase who were enrolled in a multicenter observational study i...

journal_title：European neurology

authors： Naganuma M,Mori M,Nezu T,Makihara N,Koga M,Okada Y,Minematsu K,Toyoda K,SAMURAI Study Investigators.

更新日期：2011-01-01 00:00:00

abstract：:In order to examine the plasminogen activator (PA) induction involved in the pathogenesis of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS), PA activity in peripheral blood lymphocytes derived from 5 ADEM and 3 MS patients was investigated. There was no PA induction in any ADEM, MS or control ...

journal_title：European neurology

authors： Sugita K,Suzuki N,Shimizu N,Takanashi J,Ishii M,Niimi N

更新日期：1993-01-01 00:00:00

abstract：:A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...

journal_title：European neurology

authors： Micheli F,Lehkuniec E,Giannaula R,Caputi E,Paradiso G

更新日期：1987-01-01 00:00:00

abstract：:In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

journal_title：European neurology

authors： Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

更新日期：1988-01-01 00:00:00

abstract：:In a 5-year follow-up of a case of adult metachromatic leukodystrophy, already diagnosed in the preclinical stage, the development of the symptoms of this disease could be studied in detail: initially, lack of drive, emotional lability and depressive mood. At the same time, pain in the arms and beginning gait disturba...

journal_title：European neurology

authors： Pilz H,Duensing I,Heipertz R,Seidel D,Lowitzsch K,Hopf HC,Goebel HH

更新日期：1977-01-01 00:00:00

abstract：:Percussion of the skull dates from a time when there were virtually no radiological methods for examining the skull and brain. Three apparently independent contributions appeared within the years 1893-1895. The sound elicited, tenderness, and auscultatory percussion have each been employed for diagnostic purposes, but...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:Sir William Gull coined the name 'anorexia nervosa'. Examples of self-starvation appeared in the Hellenistic era. Holy anorexics abused their bodies, rejected marriage and sought religious asylum where many perished and became saints. The condition then paled into obscurity until the 19th century. Louis-Victor Marce (...

journal_title：European neurology

authors： Pearce JM

更新日期：2004-01-01 00:00:00

abstract：:The aim of this work was to quantify the accumulation of iron in the basal ganglia in multiple sclerosis (MS) patients and in a control group, and to investigate the relationship between iron accumulation and other parameters assessed in MS, i.e. lesion load (LL) and brain parenchymal fraction (BPF). Magnetic resonanc...

journal_title：European neurology

authors： Burgetova A,Seidl Z,Krasensky J,Horakova D,Vaneckova M

更新日期：2010-01-01 00:00:00

abstract：:The biochemical process underlying Parkinson's disease is dopamine cell death of the nigrostriatal system. The age-dependent cell death is now proposed to be elicited by the formation of free hydroxy radicals which are formed from hydrogen peroxide, a product of oxidation of dopamine by monoamine oxidase, especially t...

journal_title：European neurology

authors： Naoi M,Maruyama W

更新日期：1993-01-01 00:00:00

abstract：:Embolism from the aneurysmal sac is a rare but possible manifestation of intracranial aneurysm; thrombus formation is probably related to the combined action of turbulent flow and a 'stagnant zone'. Three cases are presented: 2 with giant aneurysms (1 internal carotid and 1 sylvian) and 1 with a large aneurysm of the ...

journal_title：European neurology

authors： Parenti G,Fiori L,Marconi F

更新日期：1992-01-01 00:00:00

abstract：:Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...

journal_title：European neurology

authors： Kaido M,Fujimura H,Ono A,Toyooka K,Yoshikawa H,Nishimura T,Ozaki K,Narama I,Kuwajima M

更新日期：1997-01-01 00:00:00

abstract：:QTc intervals were measured in 30 patients with Parkinson's disease and 30 healthy control subjects. The mean value of QTc intervals in patients with Parkinson's disease significantly exceeded that of healthy controls (418 +/- 14 ms vs. 403 +/- 18 ms). Prolongation of the QTc interval was unrelated to the administrati...

journal_title：European neurology

authors： Oka H,Mochio S,Sato H,Katayama K

更新日期：1997-01-01 00:00:00

abstract：AIMS:We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer's disease (AD) patients and the interaction between MTA and WMH. METHODS:From 13 centers, a total of 216 AD patients were consecutivel...

journal_title：European neurology

authors： Shim YS,Youn YC,Na DL,Kim SY,Cheong HK,Moon SY,Park KW,Ku BD,Lee JY,Jeong JH,Kang H,Kim EJ,Lee JS,Go SM,Kim SH,Cha KR,Seo SW

更新日期：2011-01-01 00:00:00

abstract：:We report on management strategies and clinical outcomes in 4 cases of acute symptomatic congestive intracranial hypertension associated with cerebral arteriovenous malformations (AVMs). Congestion resulted from high-volume shunts exhausting the drainage capacity of the cerebral venous system in 3 patients, and from s...

journal_title：European neurology

authors： Rosenkranz M,Regelsberger J,Zeumer H,Grzyska U

更新日期：2008-01-01 00:00:00

abstract：:A case of Fisher's syndrome associated with trigeminal herpes zoster is reported for the first time. Retrograde propagation of the virus to the brainstem through the trigeminal root was thought to be the most probable pathogenic mechanism. We provide additional evidence suggesting that the focus of Fisher's syndrome i...

journal_title：European neurology

authors： Uematsu D,Satoh T,Tanahashi N,Koto A,Gotoh F

更新日期：1985-01-01 00:00:00

abstract：:The clinical and biochemical data on 13 patients with Batten's syndrome are described. Clinically the disease was characterized by progressive maental and somatic deterioration. Initially, vision loss was found between the ages 4 and 8 years. This was associated with 1 or 2 years of normal school attendance followed b...

journal_title：European neurology

authors： Jensen GE,Clausen J,Melchior JC,Konat G

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Cerebral cavernous malformations (CCMs) are intracranial vascular malformations that can exist as a single lesion or mixed vascular lesions. The most common mixed form is the coexistence of CCM with an associated developmental venous anomaly (DVA). In this paper, we aim to give a comprehensive review of CCM,...

journal_title：European neurology

authors： Idiculla PS,Gurala D,Philipose J,Rajdev K,Patibandla P

更新日期：2020-01-01 00:00:00

abstract：:In order to consider the prognostic value of hyperdensity of the middle cerebral artery (MCA), we studied retrospectively the medical records of 80 consecutive patients with the diagnosis of ischemic stroke who underwent a non-enhanced computed tomography no longer than 24 h after the onset of the symptoms. To determi...

journal_title：European neurology

authors： Zorzon M,Masè G,Pozzi-Mucelli F,Biasutti E,Antonutti L,Iona L,Cazzato G

更新日期：1993-01-01 00:00:00

abstract：:Cavernomas are vascular malformations mostly observed in the central nervous system. They occur in sporadic and familial forms. Familial forms are characterized by the presence of multiple lesions, an autosomal dominant pattern of inheritance and possible de novo lesions. We report two sporadic cases whose follow-up s...

journal_title：European neurology

authors： Labauge P,Brunereau L,Coubes P,Clanet M,Tannier C,Laberge S,Lévy C

更新日期：2001-01-01 00:00:00

abstract：:Reviewing the angiograms of 100 patients with RIA or stroke we found intracranial lesions in 67%, extracranial lesions in 64%, and normal angiograms in 13% of the cases. Risk factors occurred more often as the angiographic lesions were more extensive. These findings confirm the importance of angiographic examination o...

journal_title：European neurology

authors： van Oudenaarden WF,Tans JT,Hoogland PH

更新日期：1980-01-01 00:00:00