Effectiveness of simplified dosage schedules on the management of ambulant epileptic patients.

abstract：:MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

journal_title：European neurology

authors： Nagatsu T,Hirata Y

更新日期：1987-01-01 00:00:00

abstract：:A 49-year-old alcoholic woman was admitted for convulsions. She died after a 4-week clinical course characterized by a persistent coma with diffuse muscular hypertonia. Post-mortem examination of the brain demonstrated a spongy degeneration and gliosis of the cerebral cortex, limited to the 3rd and the 4th layers. No ...

journal_title：European neurology

authors： Naeije R,Franken L,Jacobovitz D,Flament-Durand J

更新日期：1978-01-01 00:00:00

abstract：:In a 14-year follow-up the improvement of language functions and the decrease of EEG abnormalities are described in a girl with the Landau-Kleffner syndrome. In this case, the results of subsequent EEG recordings do not permit conclusions about the course of the aphasia. Disappearance of focal spike and waves, bilater...

journal_title：European neurology

authors： van Dongen HR,Meulstee J,Blauw-van Mourik M,van Harskamp F

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Patients with multiple sclerosis (MS) report sleep disturbances (SD) and excessive daytime sleepiness (EDS) more frequently than the general population. Our objectives were to evaluate SD and EDS in MS patients and to test the reliability of subjective sleep questionnaires. METHODS:Demographic and clinical ...

journal_title：European neurology

authors： Neau JP,Paquereau J,Auche V,Mathis S,Godeneche G,Ciron J,Moinot N,Bouche G

更新日期：2012-01-01 00:00:00

abstract：:Tardive dyskinesia (TD) induced by antipsychotic drugs represents a great concern for patients and psychiatrists. Considering its pathophysiological mechanisms, there exists a convergence towards the development of postsynaptic dopaminergic hypersensitivity as a possible cause of TD. Hypersensitivity following recepto...

journal_title：European neurology

authors： Mouret J,Khomais M,Lemoine P,Sebert P

更新日期：1991-01-01 00:00:00

abstract：:Direct evidence of the anatomical localization of brain function is provided by functional neurological changes during awake surgery combined with data from preoperative functional magnetic resonance imaging and diffusion tensor imaging studies. The goal of the present study was to analyze the etiology and mechanism o...

journal_title：European neurology

authors： Shinoura N,Yoshida M,Yamada R,Tabei Y,Saito K,Suzuki Y,Yagi K

更新日期：2010-01-01 00:00:00

abstract：:An 18-year-old mongoloid girl (trisomy 21) of Asian descent presented two symptoms rarely associated with mongolism (Down's syndrome). (1) Brain stem calcification; the first case diagnosed in vivo in mongolism on computerized axial tomography. (2) Hallucinatory psychotic depression; the first case successfully treate...

journal_title：European neurology

authors： Jakab I

更新日期：1978-01-01 00:00:00

abstract：:The neuropathological diagnosis of Alzheimer's disease relies on the presence of both neurofibrillary tangles and senile plaques. The number of neurofibrillary tangles is tightly linked to the degree of dementia, suggesting that the formation of neurofibrillary tangles more directly correlates with neuronal dysfunctio...

journal_title：European neurology

authors： Brion JP

更新日期：1998-10-01 00:00:00

abstract：:Fifteen chronic alcoholic male patients with impotence have been investigated with the electrophysiological method of sympathetic skin potentials recorded from the genital skin and with the electrically induced bulbocavernosus reflex. Both electrophysiological tests did not differ from those of normal controls. It was...

journal_title：European neurology

authors： Ertekin C,Almis S,Ertekin N

更新日期：1990-01-01 00:00:00

abstract：:Although multifocal motor neuropathy (MMN) is now recognized as a distinct, albeit rare, neurological condition, the path to its recognition was long and winding. This article provides an insight into the medical history of MMN "patient zero" and the first scientific publication that led to the recognition of MMN by t...

journal_title：European neurology

authors： Ochsner F,Tatu L

更新日期：2020-11-11 00:00:00

abstract：INTRODUCTION:Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. METHODS:An in-depth ...

journal_title：European neurology

authors： Xiao Y,Chen MJ,Shen X,Lin LR,Liu LL,Yang TC,Niu JJ

更新日期：2019-01-01 00:00:00

abstract：:Increased levels of lactic dehydrogenase (LDH) in cerebrospinal fluid (CSF) have been reported in association with several intracranial pathologies. We studied LDH isoenzymes in the CSF of children with infantile spasms. CSF samples collected from 12 patients (aged 4-9 months) with infantile spasms were analyzed for t...

journal_title：European neurology

authors： Nussinovitch M,Harel D,Eidlitz-Markus T,Amir J,Volovitz B

更新日期：2003-01-01 00:00:00

abstract：:After briefly evaluating the contraindications and indications of vasoactive and eumetabolic therapy of cerebral ischemia, the paper considers the main drugs at present in use in therapy of the syndrome induced by diffused cerebral arteriosclerosis. Among the drugs with a mainly vasoactive effect, consideration is giv...

journal_title：European neurology

authors： Strano A,Pinto A,Davì G,Novo S,Riolo F

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Endovascular mechanical thrombectomy is an important approach for acute ischemic stroke (AIS) treatment. Multimodal neuroimaging methods ideally provide the exact localization, extent, and metabolic activity of target tissues. Post-stroke cognitive impairment has recently been realized to be a...

journal_title：European neurology

authors： Xu G,Dong X,Niu X,Zheng G,Wang H,Zhang F,Li L,Lv P

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Central pontine myelinolysis (CPM)/extrapontine myelinolysis (EPM) is one of the most serious neurological complications that can occur after orthotopic liver transplantation (OLT). We analyzed the risk factors for CPM/EPM in OLT patients. METHODS:We retrospectively reviewed the records of 1,247 patients wh...

journal_title：European neurology

authors： Lee EM,Kang JK,Yun SC,Kim KH,Kim SJ,Hwang KS,Lee SG

更新日期：2009-01-01 00:00:00

abstract：:Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...

journal_title：European neurology

authors： de Visser M,Ongerboer de Visser BW,Verbeeten B Jr

更新日期：1988-01-01 00:00:00

abstract：:Acid phosphatase staining is performed on cerebrospinal fluid cells of 365 samples from 105 patients with various types of meningitis. This enzyme activity is strongly positive in the early samples of bacterial meningitis, as far as the patients had not received a pretreatment with antibiotics for more than 24 h. It a...

journal_title：European neurology

authors： De Reuck JL,De Coster WJ,vander Eecken HM

更新日期：1986-01-01 00:00:00

abstract：:Sixteen children with definite multiple sclerosis (MS; aged 6-17 years, mean 11.4 +/- 2.7; 8 boys, 8 girls) were reviewed. Cerebellar symptoms and signs were frequent at initial presentation. Among laboratory studies, the cerebrospinal fluid (CSF) IgG index or oligoclonal bands were informative in 75%, evoked potentia...

journal_title：European neurology

authors： Selcen D,Anlar B,Renda Y

更新日期：1996-01-01 00:00:00

abstract：:We report a short-term double-blind, crossover study of CoQ10 in 8 patients with mitochondrial encephalomyopathies. Four patients had myoclonus epilepsy with ragged-red fibers syndrome, 3 had mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome, and 1 had chronic progressive extern...

journal_title：European neurology

authors： Chen RS,Huang CC,Chu NS

更新日期：1997-01-01 00:00:00

abstract：:A woman who had spontaneous pain, hyperpathia and wasting of her left hand due to a subcortical lesion in the right parietal lobe is reported. The presentation and evaluation of this most unusual case are discussed. ...

journal_title：European neurology

authors： Sandyk R

更新日期：1985-01-01 00:00:00

abstract：:Estrogen receptor (ER) analysis was performed with an enzyme immunoassay using monoclonal antibodies against human ER protein (estrophilin) in 70 meningiomas. [3H]methyltrienolone, a synthetic androgen, was used for concurrent determination of the androgen receptor (AR)-binding activity. Low levels of ER immunoreactiv...

journal_title：European neurology

authors： Lesch KP,Schott W,Engl HG,Gross S

更新日期：1987-01-01 00:00:00

abstract：:The pathogenesis of primary degenerative dementia is still unknown and current therapeutic approaches can aim only at ameliorating some of the symptoms associated with this brain disease. At present, most approaches, attempt to correct a cholinergic deficit. Although the therapeutic benefits obtained so far with curre...

journal_title：European neurology

authors： Markstein R

更新日期：1989-01-01 00:00:00

abstract：:While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both star...

journal_title：European neurology

authors： Bogousslavsky J,Walusinski O,Moulin T

更新日期：2011-01-01 00:00:00

abstract：:The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...

journal_title：European neurology

authors： Rocchelli B,Poloni M,Mazzarello P,Delodovici M

更新日期：1983-01-01 00:00:00

abstract：:In recent years, the involvement of the immune system in acquired forms of cerebellar ataxia has been frequently demonstrated. In this study, we describe 6 out of 49 patients with subacute or chronic progressive cerebellar ataxia in whom antibodies against neuronal and non-neuronal antigens were identified. Two women ...

journal_title：European neurology

authors： Fancellu R,Pareyson D,Corsini E,Salsano E,Laurà M,Bernardi G,Antozzi C,Andreetta F,Colecchia M,Di Donato S,Mariotti C

更新日期：2009-01-01 00:00:00

abstract：:We present a long-term follow-up examination concerning patients with isolated extra-ocular muscle involvement in thyroid-related orbitopathy. Within the previous 13 years we observed 7 patients with endocrine orbitopathy and marked myopathy of the extra-ocular muscles. Five of these patients had no detectable proptos...

journal_title：European neurology

authors： Gerlach M,Ferbert A

更新日期：2008-01-01 00:00:00

abstract：:Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...

journal_title：European neurology

authors： Hasegawa K,Kowa H

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the diagnostic yield of nerve biopsy in patients with peripheral neuropathy of undetermined cause despite extensive diagnostic workup. METHODS:From November 2001 through January 2004, 38 patients underwent nerve biopsy because of unclassified neuropathy. RESULTS:The etiology of the neuropathies...

journal_title：European neurology

authors： Schweikert K,Fuhr P,Probst A,Tolnay M,Renaud S,Steck AJ

更新日期：2007-01-01 00:00:00

abstract：:The effect of thoracic duct lymph drainage (5-34 days) in 12 patients with myasthenia gravis on muscular function has been followed for 5-43 months. Among the results obtained were: (1) During the drainage the myasthenic symptoms decreased markedly after 1-4 days and remained so during the drainage. (2) The doses of c...

journal_title：European neurology

authors： Bergström K,Franksson C,Matell G,Nilsson BY,Persson A,von Reis G,Stensman R

更新日期：1975-01-01 00:00:00

abstract：:SJL/J mice have been studied as the model animals for autoimmunological diseases. Recently it was clarified that SJL/J mice have a defect of dysferlin. Human limb girdle muscular dystrophy 2B and Miyoshi myopathy also have a defect of dysferlin. In this study we present the histological and immunohistological changes ...

journal_title：European neurology

authors： Nemoto H,Konno S,Nakazora H,Miura H,Kurihara T

更新日期：2007-01-01 00:00:00