Basal ganglia calcification and psychosis in mongolism.

Abstract:

:An 18-year-old mongoloid girl (trisomy 21) of Asian descent presented two symptoms rarely associated with mongolism (Down's syndrome). (1) Brain stem calcification; the first case diagnosed in vivo in mongolism on computerized axial tomography. (2) Hallucinatory psychotic depression; the first case successfully treated, to full recovery from the psychosis, in a mongoloid child with known brain stem calcification. The psychotic depression was related to moderate environmental stress. While being treated in her parent's home, in their native land, for more than 1 year, the psychosis remained unresponsive to tranquilizers. Following hospital admission in the USA, rapid improvement was obtained within a few weeks through intensive milieu therapy.

journal_name

Eur Neurol

journal_title

European neurology

authors

Jakab I

doi

10.1159/000114963

keywords:

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

300-14

issue

5

eissn

0014-3022

issn

1421-9913

journal_volume

17

pub_type

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