Abstract:
BACKGROUND:Cerebral cavernous malformations (CCMs) are intracranial vascular malformations that can exist as a single lesion or mixed vascular lesions. The most common mixed form is the coexistence of CCM with an associated developmental venous anomaly (DVA). In this paper, we aim to give a comprehensive review of CCM, DVA, and their coexistence as mixed lesions. A PubMed search using the keywords "Cerebral cavernous malformations, Developmental venous anomaly, Mixed Cerebral cavernous malformations with Developmental venous anomaly" was done. All studies in the English language in the past 10 years were analyzed descriptively for this review. SUMMARY:The search yielded 1,249 results for "Cerebral cavernous malformations," 271 results for "Developmental venous anomaly," and 5 results for "Mixed Cerebral cavernous malformations with Developmental venous anomaly." DVA is the most common intracranial vascular malformation, followed by CCM. CCM can have a wide array of clinical presentations like hemorrhage, seizures, or focal neurological deficits or can also be an incidental finding on brain imaging. DVAs are benign lesions by nature; however, venous infarction can occur in a few patients due to acute thrombosis. Mixed CCM with DVA has a higher risk of hemorrhage. CCMs are angiographically occult lesion, and cerebral digital subtraction angiography is the gold standard for the diagnosis of DVA. Mixed lesions, on the other hand, are best diagnosed with magnetic resonance imaging, which has also been effective in detecting specific abnormalities. Asymptomatic lesions are treated through a conservative approach, while clinically symptomatic lesions need surgical management. CONCLUSION:Individual CCM or DVA lesions have a benign course; however, when they coexist in the same individual, the hemorrhagic risk is increased, which prompts for rapid diagnosis and treatment.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Idiculla PS,Gurala D,Philipose J,Rajdev K,Patibandla Pdoi
10.1159/000508748subject
Has Abstractpub_date
2020-01-01 00:00:00pages
360-368issue
4eissn
0014-3022issn
1421-9913pii
000508748journal_volume
83pub_type
杂志文章,评审abstract:OBJECTIVE:To determine whether orbitofrontal cortex (OFC) function improves with blepharospasm (BSP) symptom remission using a verbal fluency task and near-infrared spectroscopy (NIRS). METHODS:Nineteen BSP patients and 9 healthy controls (HCs) matched by gender and education were examined using NIRS. The BSP patients...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000471850
更新日期:2017-01-01 00:00:00
abstract::Positron emission tomography (PET) has opened new fields of investigation on clinicometabolic correlations in subcortical infarcts. Functional changes occurring in structurally unaffected brain regions represent one of the most interesting aspects of PET application. So far, the only one PET study on lacunar infarcts ...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000116466
更新日期:1989-01-01 00:00:00
abstract::A double-blind controlled trial was performed on 6 patients affected with Steinert's disease in order to evaluate the efficacy of two different dosages of diphenylhydantoin (PHT, 200 and 300 mg/day) and carbamazepine (CBZ, 600 and 800 mg/day) on the myotonic afterdischarge. Both dosages of PHT and CBZ induced a signif...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000115546
更新日期:1983-01-01 00:00:00
abstract::197 cases of patients with CVI, subjected to surgery by carotid endarterectomy, are examined. The results were nearly always good and hence the technique is recommended. Particular interest is attached to the risk connected with carotid clamping, through intraoperative study of CBF with 133Xe, such a risk is practical...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115010
更新日期:1978-01-01 00:00:00
abstract::Two cases are presented with a long clinical history of multiple sclerosis (MS) before the diagnosis of an intracranial brain tumor. In the subsequent brain autopsy, however, both cases presented a diffusely growing anaplastic astrocytoma, only, and no changes similar to MS were seen. Diffuse tumor growth was noted in...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116009
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Hypertension and hyperhomocysteinemia (HHcy) are independent risk factors of stroke and are associated with each other. Although evidence suggests that they are related to cognitive impairment, the relationship between hypertension accompanied with HHcy and poststroke cognitive impairment (PSCI) is unclear. ...
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更新日期:2019-01-01 00:00:00
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pub_type: 历史文章,杂志文章
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journal_title:European neurology
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journal_title:European neurology
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journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000096488
更新日期:2006-01-01 00:00:00
abstract::In a group of 60 patients of which 30 were affected by myasthenia, we used the regional curare test. The results were evaluated from a critical point of view and were then compared with the results obtained by the repetitive stimulation of the circumflex nerve, deriving from deltoid muscle. We considered too the speci...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114813
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in p...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000487717
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Central pontine myelinolysis (CPM)/extrapontine myelinolysis (EPM) is one of the most serious neurological complications that can occur after orthotopic liver transplantation (OLT). We analyzed the risk factors for CPM/EPM in OLT patients. METHODS:We retrospectively reviewed the records of 1,247 patients wh...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000242426
更新日期:2009-01-01 00:00:00
abstract::The frontal lobe is the largest lobe of the brain, and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas. This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkabl...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000117068
更新日期:1994-01-01 00:00:00
abstract::Trials of pharmacological intervention for acute stroke show several points of similarity with legal trials by jury. The relationships between sponsoring organisation and regulatory authorities and the roles of the many other participants are described. Only through a partnership can the common aim of developing impro...
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pub_type: 杂志文章
doi:10.1159/000068509
更新日期:2003-01-01 00:00:00
abstract::Machado-Joseph disease (MJD) is a dominantly inherited cerebellar ataxia associated with spasticity, ophthalmoplegia, dystonia and peripheral neuropathy. Presented here are 5 MJD cases. A morphometric analysis of the histopathology of their sural nerves was carried out to know the relationship between axon size and my...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000066169
更新日期:2002-01-01 00:00:00
abstract::Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116656
更新日期:1991-01-01 00:00:00
abstract::About one third of patients with newly diagnosed epilepsy do not achieve seizure control despite medical therapy and should be assessed in detail to confirm the diagnosis, to determine the epilepsy syndrome and to plan treatment strategy. Refractory epilepsy is established when there is inadequate seizure control desp...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000222775
更新日期:2009-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115164
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pub_type: 杂志文章
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journal_title:European neurology
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更新日期:1979-01-01 00:00:00
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journal_title:European neurology
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更新日期:2014-01-01 00:00:00
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journal_title:European neurology
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更新日期:1989-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116120
更新日期:1987-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116035
更新日期:1986-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114682
更新日期:1975-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115486
更新日期:1982-01-01 00:00:00